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Case Report
Chronic Epstein-Barr virus infection causing both benign and malignant lymphoproliferative disorders
Yoojin Kwun, Soo-Jong Hong, Jin Seong Lee, Da Hye Son, Jong Jin Seo
Clin Exp Pediatr. 2014;57(9):420-424.   Published online September 30, 2014

The Epstein-Barr virus (EBV) is oncogenic and can transform B cells from a benign to a malignant phenotype. EBV infection is also associated with lymphoid interstitial pneumonia (LIP). Here, we report the case of a 14-year-old boy who was diagnosed with a latent EBV infection and underlying LIP, without any associated immunodeficiency. He had been EBV-seropositive for 8 years. The...

Original Article
Nationwide surveillance of acute interstitial pneumonia in Korea
Byoung-Ju Kim, Han A Kim, Young-Hwa Song, Jinho Yu, Seonguk Kim, Seong Jong Park, Kyung Won Kim, Kyu-Earn Kim, Dong Soo Kim, June Dong Park, Kang Mo Ahn, Hyo-Bin Kim, Hyang-Min Jung, Chun Kang, Soo-Jong Hong
Clin Exp Pediatr. 2009;52(3):324-329.   Published online March 15, 2009
Purpose : Acute interstitial pneumonia (AIP) is a rare disease, but its prognosis is fatal because of lack of efficient treatment modality. Recently, it has been reported that there was epidemic AIP in Korea. This study aims to investigate the past and current status of AIP in Korea. Methods : We performed a nationwide survey and a prospective study. From August...
Epidemic acute interstitial pneumonia in children occurred during the early 2006s
Chong Kun Cheon, Hyun-Seung Jin, Eun Kyeong Kang, Hyo Bin Kim, Byoung-Joo Kim, Jinho Yu, Seong Jong Park, Soo-Jong Hong, June Dong Park
Clin Exp Pediatr. 2008;51(4):383-390.   Published online April 15, 2008
Purpose : This study was aimed to analyze the clinical characteristics of patients with acute interstitial pneumonia who had presented similar clinical patterns from March to June, 2006 and to describe our experience of treatment and to identify risk factors associated with prognosis. Methods : The clinical characteristics, radiologic and histopathologic findings and response to steroids of 15 patients (non-survival...
Case Report
A Case of Idiopathic Interstitial Pneumonia in Childhood
Su-Jin Lee, Eon-Woo Shin, Eun-Young Park, Phil-Soo Oh, Kon-Hee Lee, Kwang-Nam Kim, Ho-Seung Shin, Il-Seung Lee
Clin Exp Pediatr. 2005;48(3):327-332.   Published online March 15, 2005
Interstitial lung disease refers to a group of pulmonary disorders characterized by inflammation of the interstitium, derangements and loss of alveolar capillary units leading to disruption of alveolar gas exchange, which induces symptoms of restrictive lung disease. Cases of interstitial pneumonia in children are uncommon and mostly have unknown causes. We have experienced an 8-year old boy who had symptoms...
A Case of Nonspecific Interstitial Pneumonia in a Child
Tae Wan Kim, Dae-Hyun Lym, Jung Hee Kim, Byong Kwan Son, Hye-Seung Han, Young Kyu Shin
Clin Exp Pediatr. 2002;45(4):529-534.   Published online April 15, 2002
Department of Pediatrics†, College of Medicine, Korea University, Seoul, Korea Interstitial pneumonia is a heterogenous group of inflammatory and fibrosing lesions that manifest themselves as infiltrative lung disease. Of these, nonspecific interstitial pneumonia is characterized as a variable degree of interstitial inflammation with or without fibrosis and is distinguished from usual interstitial pneumonia and desquamative interstitial pneumonia, histologically. The influx of...
A Case of Lymphocytic Interstitial Pneumonia
Ho Young Lee, Hwang Min Kim, Mee Kyung Namgoong, Jong Soo Kim, Soon Hee Jung, Dong Jin Kim
Clin Exp Pediatr. 1997;40(4):572-577.   Published online April 15, 1997
Lymphoid interstitial pneumonia(LIP) is an uncommon process in childhood, and is characterized by interstitial accumulation of mature lymphocytes, plasma cells and reticuloendothelial cells. LIP is believed to have autoimmune or immunologic pathogenesis, because it is frequently associated with acquired immune deficiency syndrome, Epstein-Barr virus infection, common variable immunodeficiency. The patient described in this report had idiopathic thrombocytopenic purpura, Evans syndrome...
Original Article
A Case of Child Desquamative Interstitial Pneumonia.
Woo Taek Kim, Hyoung Doo Lee, Yung Tak Lim, Hee Joo Jeon, Hee Joo Park, Chan Yung Kim
Clin Exp Pediatr. 1989;32(1):92-100.   Published online January 31, 1989
Desquamative interstitial pneumonia (DIP) is a variant of idiopathic interstitial pneumonias, but characteristicalIy has massive desquamation and proliferation of alveolar cells into the distal air space with minimal fibrosis of the alveolar wall. DIP seems to have better response to corticosteroid and benign prognosis than idiopathic interstitial pneumonia. We experienced one case of 6-year old girl who showed typical picture of DIF on lung...
Clinical Studies on Interstitial Pneumonitis in Children.
Young Yull Ko, Kwang Wook Ko, Jw Geun Chi
Clin Exp Pediatr. 1985;28(7):663-673.   Published online July 31, 1985
Interstitial pneumonitis is a rare, diffuse lung disease characterized by varing combinations of two histological features: thickening of alveolar walls and the presence of large mononuclear cells in the alveolar spaces. 4 cases with interstitial pneumonitis, admitted to the Pediatric Department of Seoul National University Hospital during the period from Jan. 1979 through. May, 1985 were reviewed clinically. The results...
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