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Original Article
Analysis of Etiology and Prognosis of Pulmonary Complications in Children with Hematological or Oncological Disorders in Pediatric Intensive Care Unit
Jin Young Jung, Soo-Jong Hong, Young Jun An, Ja Hyung Kim, Jong Jin Seo, Hyung Nam Moon, Thad Ghim
Clin Exp Pediatr. 2002;45(8):1000-1006.   Published online August 15, 2002
Purpose : In the course of treatment, patients with hematological or oncological disorders often develop pulmonary complication. The patients who develop a severe pulmonary complication have a poor outlook. The causes of pulmonary complication are either infectious or non-infectious in origin. We have analyzed the etiology and outcome of these patients admitted to the pediatric intensive care unit of Asan...
Case Report
Malignant Ectomesenchymoma in a Two-Month-Old Boy
Ji Young Hwang, Ji Hyoun Seo, Jeum-Su Kim, Young-Suk Kim, Sue-Jin Lee, Chan-Hoo Park, Yoo Kyung Kim, Sun Hoo Park, Jung Hee Lee, In Oak Ahn, Ki Hyun Chung, Byung-Kiu Park
Clin Exp Pediatr. 2001;44(8):959-964.   Published online August 15, 2001
Malignant ectomesenchymoma is a rare tumor originating from remnants of migratory neural crest(ectomesenchyme) and composed of neuroectodermal as well as mesenchymal components. Neuroblasts and ganglion cells constitute the neuroectodermal components and rhabdomyosarcoma is the most frequently encountered mesenchymal components. We report a case of malignant ectomesenchymoma in a two-month-old boy who was presented with abdominal pain and urinary difficulty. The...
Original Article
Immunohistochemical Studies on Neuroendocrine Markers in Malignant Neuronal Tumors (Neuroblastoma and Ganglioneuroblastoma) in Children
Woo Yeong Chung, Sun Kyung Lee
Clin Exp Pediatr. 1992;35(10):1377-1388.   Published online October 15, 1992
The authors studied 24 cases of malignant neuronal tumors, 14 neuroblastomas and 10 ganglioneuroblastomas, immunohistochemically, using antibodies to neuroendocrine markers including neuron specific enolase (NSE), somatostatin, chromogranin, β-endorphin, and adrenocorticotrophic hormone (ACTH). The tissue specimens were obtained by biopsy or autopsy at Pusan National University Hopital and Pusan Paik Hospital from 1980 to 1989. The positive reactivity of markers in...
A case of malignant atrophic papulosis (Degos' disease).
Sung Ku Lee, In Seok Lim, Chul Ha Kim, Dong Keun Lee, Eung Sang Choi, Byoung Hoon Yoo, Gae Yong Song
Clin Exp Pediatr. 1991;34(12):1724-1729.   Published online December 31, 1991
Malignant atrophic papulosis (Degos’ disease) is characterized by porcelain-white skin lesions. It has unknown etiology and bad prognosis. Death usually occurs from multiple intestinal perforations weeks to years after onset. We experienced a case of Degos’ disease in a 12-year-old male patient who had porcelain white papules on face, trunk and extremities. Histopathologic studies showed broad epidermal necrobiosis with thrombotic arteriolar occlusion. A brief review of...
A case of acute lymphoblastic leukemia complicating neuroblastoma in remission.
Dong Woo Son, Bum Soo Park, Jun Jae Kim, Hong Hoe Koo, Hee Young Shin, Hyo Seop Ahn
Clin Exp Pediatr. 1991;34(5):720-729.   Published online May 31, 1991
As childhood cancer survivors are now increasing in number owing to the improvements in diagnosis, staging, and treatment, concerns have been raised regarding the quality of survival of these patients. One of the limitation to quality and length of survival has been the development of second malignant neoplasm (SMN). In Korea, only one case of SMN has been reported. However, one can expect that...
Osteogenic Sarcoma as Second Malignant Neoplasm After Treatment of Retinoblastoma.
Ja Young Kim, Moon Whan Lee, Ju Hyung Kim, Pyoung Han Hwang, Jung Soo Kim
Clin Exp Pediatr. 1990;33(12):1735-1740.   Published online December 31, 1990
The improvement in survival for childhood cancer has been achieved through the use of multiple- agent chemotherapy and radiotherapy. However, one of the limitations to quality and length of survival has been the development of second malignant neoplasm. We exprienced a case of second malignant neoplasm in 13-year-old boy who developed osteogenic sarcoma after successful treatment of retinoblastoma. At 3 years of his age,...
A case of Endobronchial Metastatic Malignant Melanoma.
Sang Hee Kim, Young Kyoo Shin, Kwang Chul Lee, Chang Sung Son, Pyung Hwa Choe
Clin Exp Pediatr. 1990;33(4):573-578.   Published online April 30, 1990
Metastatic malignant melanoma is a rare neoplasm in child. We experienced a case of endobron- chial metastatic malignant melanoma developed in a 5 year-8month-old boy, who was admitted because of dyspnea and productive cough. Diagnosis was made by endobrochia 1 biopsy and histopathologic findings. He was treated with radiation as a palliative therapy. The result was good. Tumor size decreased and symptoms im- proved. The...
A case of Second Malignant Neoplasm Complicating Hodgkin's Disease in Remission.
Hong Hoe Koo, Jong Woon Choi, Sang Oh Na, Il Soo Ha, Hee Young Shin, Hyo Seop Ahn, Yeon Lim Suh, Chul Woo Kim, Je Geun Chi
Clin Exp Pediatr. 1990;33(4):564-572.   Published online April 30, 1990
Recent advances in the treatment of cancer have resulted in increased survival and possible cure for many malignant disorders, particularly childhood cancers. There has been a marked improvement in the treatment of childhood Hodgkin’s disease, and five-year survival rates for even advanced stages of Hodgkin’s disease approach or exceed more than 75% with modern treatment policies. However, successful therapy in childhood cancer is frequently...
A Case of Malignant Ependymoma.
Ja Wook Koo, Sun Ho Lee, In Joon Seol, Hahng Lee
Clin Exp Pediatr. 1989;32(1):130-136.   Published online January 31, 1989
Intracranial tumors presenting in the first year of life are uncommon. Brain tumors in infancy are predominantly supratentorial, whereas in older children the majority are infratentorial. Malignant ependymoma is a rare type of primitive ependymal tumor with clinically high malignancy. We experienced a malignant ependymoma in a 5 month old girl who had progressive enlargement of head circumference with vomiting. Brain computed tomography revealed...
A Case of the Malignant Mesenchymoma of the Liver in Childhood.
Byung An Shim, Nak Wan Choe, King Yeob Han, Dong Keun Lee
Clin Exp Pediatr. 1987;30(12):1433-1438.   Published online December 31, 1987
Malignant mesenchymoma of the liver is extremely rare in childhood. It is formed by 2 or more unrelated mesenchymal tissues, chacterized by rapid growth and poor responsiveness to all modes of therapy. We experienced a case of malignant mesenchymoma of the liver in a 11-year-old boy who was admitted because of abdominal pain, anorexia, nausea and vomiting. Radiographic examinations showed a space occupying lesion...
A Study of Frequency of Malignant Tumors in Children.
Yang Dong Park, Eun Sook Choi, Hyun Gi Jung, Jae Sun Park
Clin Exp Pediatr. 1986;29(10):1130-1137.   Published online October 31, 1986
315 cases of malignant tumors under 15 years of age who were admitted to the Gospel Hospital from January 1975 to December 1984 were analysed and following results were obtained. 1) The incidence of malignances in all admitted child patient was 3.39%. 2) Childhood malignant tumors were more frequently occured in the age group of 0〜5 years. The more prevalent tumors for the...
Case Report
Prednisolone-responsive Malignant Osteopetrosis: a case reveiw.
Chong Woo Bae, Hwan Sup Kang, Jeong Sik Min, Suk Chul Kang, Soo Woong Lee
Clin Exp Pediatr. 1982;25(5):512-517.   Published online May 31, 1982
The authors presented a 17 months old female with malignant osteopetrosis, who was admitted to the Pediatric Department of Kyung Hee University Hospital on May, 1981 because of epistaxis and growth retardation. Diagnosis was made by typical clinical manifestations, hematologic and radiologic findings, such as frontal bossing, opened anterior fontanel, exophalmoses, strabismus, optic atropy, marked hepatosplenomegaly, severe anemia, thrombocytopenia, reticulocytosis...
Original Article
Clinical Observation of Malignant Tumors in Children.
Jin Oh Chang, Won Ho Choi, In Kee Paick, Chin Moo Kang
Clin Exp Pediatr. 1981;24(1):63-69.   Published online January 15, 1981
A total 147 cases of malignant tumors in children under 15 years of age who admitted Presbyterian Medical Center, Keimyung University for 6 years from Jan. 1973 to Dec. 1978 were analyzed clinically and the following results were obtained. 1) The incidence of malignancies on all admitted cases was 1.7% and the annual incidence was 1.4~2.0% without any annual increase...