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Case Report
Neurology
Complete occlusion of the right middle cerebral artery associated with Mycoplasma pneumoniae pneumonia
Ben Kang, Dong Hyun Kim, Young Jin Hong, Byong Kwan Son, Myung Kwan Lim, Yon Ho Choe, Young Se Kwon
Clin Exp Pediatr. 2016;59(3):149-152.   Published online March 31, 2016

We report a case of a 5-year-old girl who developed left hemiparesis and left facial palsy, 6 days after the initiation of fever and respiratory symptoms due to pneumonia. Chest radiography, conducted upon admission, showed pneumonic infiltration and pleural effusion in the left lung field. Brain magnetic resonance imaging showed acute ischemic infarction in the right middle cerebral artery territory....

Original Article
Sensitization rates of airborne pollen and mold in children
So Hyun Park, Dae Hyun Lim, Byong Kwan Son, Jeong Hee Kim, Young Eun Song, In Bo Oh, Yang Ho Kim, Keun Hwa Lee, Su Young Kim, Sung Chul Hong
Clin Exp Pediatr. 2012;55(9):322-329.   Published online September 14, 2012
Purpose

Aeroallergens are important causative factors of allergic diseases. Previous studies on aeroallergen sensitization rates investigated patients groups that had visited pediatric allergy clinics. In contrast, we investigated sensitization rates in a general population group of elementary school to teenage students in Incheon, Jeju, and Ulsan.

Methods

After obtaining parental consent, skin-prick tests were performed on 5,094 students between March and June 2010....

Comparison of air pollution and the prevalence of allergy-related diseases in Incheon and Jeju City
Su Ho Jeong, Jeong Hee Kim, Byong Kwan Son, Seong Chul Hong, Su Young Kim, Geun Hwa Lee, Dae Hyun Lim
Clin Exp Pediatr. 2011;54(12):501-506.   Published online December 31, 2011
Purpose

A high level of air pollutants can increase the number of patients with allergy-related diseases such as asthma and allergic rhinitis (AR). To analyze the association between air pollution and allergic disease, we investigated 2 areas in Korea: Incheon, an industrial area, and Jeju, a non-industrialized area.

Methods

Second grade students at elementary schools (11 schools in Incheon and 45 schools in...

Comparison between adverse effects of low and usual doses of intravenous aminophylline
Bok Ki Kim, Dae Hyun Lim, So Hyun Ahn, Jong Hoon Kwa, Jeong Hee Kim, Byong Kwan Son
Clin Exp Pediatr. 2009;52(4):441-445.   Published online April 15, 2009
Purpose : Some patients develop side effects from theophylline even at low serum concentrations. We designed a prospective study to evaluate the side effects of theophylline. Methods : A Prospective, controlled trial study was conducted. The low-dose group received an intravenous continuous aminophylline dose of 5 mg/kg/day on the first day and subsequently 10 mg/kg/day on the following two days....
A study of mothers knowledge of weaning of infants with iron-deficiency anemia
Sung Jin Kim, Dong Hyun Kim, Joo Hee Chang, Yong Hun Jun, Young Jin Hong, Byong Kwan Son, Soon Ki Kim
Clin Exp Pediatr. 2008;51(5):468-473.   Published online May 15, 2008
Purpose : Iron-deficiency anemia (IDA) is still one of the most common nutrient deficiency disorders, despite improvements in general health and nutrition. This study was designed to investigate the diagnostic values of hematological profiles, including the level of ferritin, and to evaluate the knowledge of mothers on weaning practices for infants and young children with IDA. Methods : This study...
Subclinical rickets in breastfed infants
Sin Young Park, Sung Woo Park, Sung Kil Kang, Yong Hoon Jun, Soon Ki Kim, Byong Kwan Son, Jee Eun Lee
Clin Exp Pediatr. 2007;50(12):1188-1193.   Published online December 15, 2007
Purpose : The prevalence of rickets in the world is on the rise not only in developing but also in developed countries. In Korea, breastfeeding has increased. There have been few studies on the possible association of rickets with breastfeeding. The purpose of this study was to identify the development and the clinical presentation of subclinical rickets in breastfed infants. Methods...
Review Article
Allergic skin test
Byong Kwan Son, Dae Hyun Lim
Clin Exp Pediatr. 2007;50(5):409-415.   Published online May 15, 2007
Allergy skin prick test and intradermal test represent one of the major tools in the diagnosis of IgE- mediated diseases like as atopic asthma, allergic rhinitis, atopic dermatitis, food and drug allergy, and insect bite when properly performed. Skin tests are of particular importance in fields such as allergen standardization, pharmacology, and epidemiology. Even if skin tests seem easy to...
Case Report
A case of acquired acrodermatitis enteropathica with a normal serum zinc level but a low level in the hair
Kyung Il Oh, Jung Hee Kim, Ji Eun Lee, Dae Hyun Lim, Byong Kwan Son
Clin Exp Pediatr. 2007;50(2):209-212.   Published online February 15, 2007
Acrodermatitis enteropathica (AE) is a rare autosomal recessive disorder of early infancy, and is characterized by periorificial dermatitis, alopecia, and intractable diarrhea. Serum zinc levels are usually low in untreated patients and the oral administration of zinc sulfate can clear skin lesions and other symptoms. Although premature and cow`s milk-fed infants are at particular risk of developing AE, there have...
Original Article
Severe hypernatremic dehydration in a breast-fed neonate
Yun Jung Oh, Ji Eun Lee, So Hyun An, Yang Kyong Kim, Sung Kil Kang, Ja Kyoung Kim, Byong Kwan Son, Yong Hoon Jun
Clin Exp Pediatr. 2007;50(1):85-88.   Published online January 15, 2007
Although it is a rare condition, breast-feeding may result in hypernatremic dehydration. However, incidences might be increasing with more mothers breast-feeding. Although the early detection and management of hypernatremic dehydration from breast-feeding is important, its prevention is even more important on account of its serious complications. In order to prevent hypernatremic dehydration secondary to breast-feeding, it is essential to educate...
The iron status and the relationship between iron deficiency and body mass index in middle school girls
Hee Youn Han, Chang Joo Hee, Hae Sun Shim, Young Jin Hong, Byong Kwan Son, Hwan Cheol Kim, Soon Ki Kim
Clin Exp Pediatr. 2006;49(11):1174-1179.   Published online November 15, 2006
Purpose : Obesity and iron deficiency are common nutritional problems. Obese children are known to have iron deficiencies, but one presented opposite opinion in Korea. This study investigated the prevalence of obesity and iron deficiency in Incheon and the relationship between iron deficiency and obesity. Methods : Physical measurement and hematologic examinations were done a 764 healthy female students aged 14...
Fine needle aspiration cytology of enlarged lymph nodes in children and adolescents
Seung Min Lee, Yoon Jung Oh, Yong Hoon Jun, Young Jin Hong, Byong Kwan Son, Soon Ki Kim, Jee Young Han, Young Chae Chu
Clin Exp Pediatr. 2006;49(2):167-172.   Published online February 15, 2006
Purpose : Palpable lymph nodes are common in the pediatric population, and most of them are either inflammatory or congenital. As the diagnostic evaluation, fine needle aspiration cytology (FNAC) is known to be more convenient and economical than tissue biopsy. We evaluated the usefulness of FNAC in children and adolescents. Methods : Four hundred and thirteen FNAC samples(M : F=1...
Clinical features of children's brain tumors according to location
Seung Jeong Han, Yun Hee Kim, Young Se Kwon, Yong Hoon Jun, Soon Ki Kim, Byong Kwan Son
Clin Exp Pediatr. 2006;49(1):76-81.   Published online January 15, 2006
Purpose : This study evaluated the clinical characteristics of brain tumors in children according to their location, the parental delay and the doctor's delay between the onset of symptoms and the diagnosis of a pediatric brain tumor. In addition, this study compared the relationship between the pre-diagnostic symptomatic interval and the tumor location. Methods : A retrospective study was undertaken of...
Clinical Characteristics of Neonatal Status Epilepticus
Kyeong Hun Jung, Yun Hee Kim, Young Se Kwon, Yong Hoon Jun, Soon Ki Kim, Byong Kwan Son
Clin Exp Pediatr. 2005;48(12):1342-1347.   Published online December 15, 2005
Purpose : Among perinatal risk factors, neonatal seizures are one of the strongest independent discriminators of adverse outcome, representing high risks of mortality and neurologic morbidity. This study was undertaken to evaluate the neurologic outcome of neonatal status epilepticus according to underlying etiology, seizure pattern, onset time, and duration. Methods : We reviewed retrospectively 36 neonates(19 males, 17 females) with status...
Case Report
A Case of Atypical Teratoid/Rhabdoid Tumor Arising from the Supratentorial Area
Kyeong Hun Jung, Young Se Kwon, Yong Hun Jun, Soon Ki Kim, Young Jin Hong, Byong Kwan Son, Eun Young Kim, In Suh Park
Clin Exp Pediatr. 2005;48(2):228-231.   Published online February 15, 2005
Atypical teratoid/rhabdoid tumor may arise at any central nervous system location, but it is most commonly located in the cerebellum(60 percent). The incidence of this tumor remains unclear but it occurs most commonly in children less than 2 years of age. This highly malignant tumor shows a rapid progression and nonspecific radiologic findings. We report a case of primary intracranial...
A Case of Pyomyositis and Toxic Shock Syndrome Caused by Methicillin Resistant Staphylococcus aureus
Yang Kyong Kim, Dal Hyon Kim, Soon Ki Kim, Byong Kwan Son, Young Jin Hong
Clin Exp Pediatr. 2005;48(1):88-92.   Published online January 15, 2005
Pyomysitis is a primary acute bacterial infection of large skeletal muscule, usually occuring in the absence of specific cause of infection. Pyomyositis has been reported mainly in tropical countries and was rare in temperate climates. but it has been recognized with increasing frequency. Toxic shock syndrome(TSS) is an acute mutisystemic disease characterized by high fever, hypotension, multisystem dysfunction and erythematous...
Original Article
The Prevalence of Obesity, Serum Lipid Levels and Age at Menarche in Adolescent Female Athletes
Bo Young Kang, Yang Kyong Kim, Young Jin Hong, Byong Kwan Son, Kyung Ja Chang, Soon Ki Kim
Clin Exp Pediatr. 2005;48(1):21-26.   Published online January 15, 2005
Purpose : The aim of this study is to find the prevalence of obesity, the serum lipid levels and the age at menarche in adolescent female athletes and to examine the effects of exercise in adolescent stage. Methods : With a questionnaire regarding their age at menarche, physical measurement, body fat, and blood samples of the serum lipid levels to...
Case Report
A Case of Dieulafoy's Lesion Presenting Upper Gastrointestinal Bleeding in a Child in the Acute Phase of Kawasaki Disease
Seung Min Lee, Seok Woo Park, Yun Hee Kim, Ji Eun Lee, Young Jin Hong, Byong Kwan Son
Clin Exp Pediatr. 2004;47(10):1124-1127.   Published online October 15, 2004
Dieulafoy's lesion is an unusual cause of massive gastrointestinal bleeding resulting from the erosion of an abnormally large submucosal artery. Recently, improvement of endoscopic techniques has made effective hemostasis possible in most cases of Dieulafoy's lesion. Aspirin, which is an anti-inflammatory agent, increases the incidence of major upper gastrointestinal complications. Gastroduodenal mucosal injury associated with aspirin therapy in patients in...
Original Article
Characteristics of Developmentally Delayed Infants and Young Children Who Demonstrated Normal Myelination by Brain MRI
Young Se Kwon, Yong Hoon Jun, Young Jin Hong, Byong Kwan Son, Kyoung Hee Lee
Clin Exp Pediatr. 2004;47(10):1081-1086.   Published online October 15, 2004
Purpose : To evaluate the clinical characteristics of infants and young children who had developmental delay without delayed myelination and dysmyelination. Methods : We retrospectively reviewed 59 cases of developmental disability between July 1996 and June 2001 at Inha University Hospital. Twenty-eight patients showed normal myelination(Group I), while thirty-one patients showed delayed myelination(Group II) by brain MRI. The following clinical records...
Iron Deficiency Anemia and Iron Nutrition in Adolescent Female Athletes
Yang Kyong Kim, Bo Young Kang, Young Jin Hong, Byong Kwan Son, Kwang Hoi Kim, Soon Ki Kim
Clin Exp Pediatr. 2004;47(10):1041-1046.   Published online October 15, 2004
Purpose : Iron deficiency, particularly iron deficiency anemia(IDA) often not only decreases athletic performance but also impairs immune function and leads to other physiologic dysfunctions. This study was designed to assess and compare iron status and the IDA prevalence in female adolescent athletes with those of general adolescent students. Methods : Physical measurements and hematologic examinations were performed for adolescent...
Case Report
A Case of Systemic Sclerosis in a Child
Ji Yeon Chang, Ja Kyoung Kim, Jeong Hee Kim, Dae Hyun Lim, Byong Kwan Son, Jung Soo Song
Clin Exp Pediatr. 2004;47(2):214-216.   Published online February 15, 2004
Systemic sclerosis is a connective tissue disease involving primarily the skin and subcutaneous tissue but may involve other organ systems such as the lungs, gastrointestinal tract, and heart. Systemic sclerosis is a rare childhood disease. The age of onset for patients with systemic sclerosis has its peak between 30 and 50 years of age. Only 1 to 2% of all...
Original Article
The Efficacy of Proximal Esophageal 24-hour pH Monitoring in Infants with Chronic Cough
Yun Hee Kim, Ja Kyoung Kim, Jung Hee Kim, Dae Hyun Lim, Byong Kwan Son
Clin Exp Pediatr. 2003;46(12):1242-1247.   Published online December 15, 2003
Purpose : Gastroesophageal reflux disease(GERD) is known as one of the most common causes of chronic cough, especially in children. The purpose of this study is to evaluate the efficacy of parameters from proximal esophageal 24-hr pH monitoring through its comparison with those of distal esophageal 24-hr pH monitoring that we generally use for diagnosis of GERD. Methods : We performed...
Relationship between Body Fat Distribution and Metabolic Risk Factors in Adolescents
Dal Hyun Kim, Tae Jung Seong, Young Jin Hong, Byong Kwan Son, Soon Ki Kim
Clin Exp Pediatr. 2003;46(4):326-334.   Published online April 15, 2003
Purpose : The objectives of this study were to estimate the prevalence of obesity in adolescents; to study the association between obesity, blood pressure, and dyslipidemia; and to evaluate the superiority of waist circumference to waist/hip ratio(WHR) in central obesity. Methods : We selected 1382 adolescents(M : F=690 : 692) aged from 11 to 18 years(mean age; boys 15.0, girls 15.4)...
Effective Screening Test for Obesity in Obese Adolescents and the Correlation Among Obesity Index, Body Mass Index and Serum Lipid Profile
Tae Jung Sung, Dal Hyun Kim, Young Jin Hong, Byong Kwan Son, Kyung Ja Chang, Jun Young Park, Soon Ki Kim
Clin Exp Pediatr. 2003;46(3):217-223.   Published online March 15, 2003
Purpose : Every year, there is a remarkable increase in the prevalence of children with excess body fat. The aim of this study is to find a useful screening method in assessing adolescent, obesity and to specify the predictable risk factors that are related to adult cardiovascular disease according to BMI and obesity index. Methods : From July to November in...
Case Report
A Case of Krabbe Disease with Infantile Spasm
Ja Kyoung Kim, Dal Hyun Kim, Bo Young Kang, Young Se Kwon, Young Jin Hong, Byong Kwan Son, Hye Ran Yoon
Clin Exp Pediatr. 2003;46(1):95-99.   Published online January 15, 2003
Krabbe disease is a rare autosomal recessive disorder clinically characterized by retardation in motor development, prominent spasticity, seizures, and optic atrophy. Pathologically, there are many globoid cells in the white matter, in addition to the lack of myelin and the presence of severe gliosis. Hence Krabbe disease is known as globoid cell leukodystrophy. Biochemically, the primary enzymatic deficiency in Krabbe...
A Case of Centronuclear Myopathy
Yun Hee Kim, Yun Hee Kim, Young Se Kwon, Young Se Kwon, Dae Hyun Lim, Dae Hyun Lim, Yong Hun Jun, Yong Hun Jun, Soon Ki Kim, Soon Ki Kim, Young Jin Hong, Young Jin Hong, Byong Kwan Son, Byong Kwan Son, Hae Seung Han, Hea Seung Han
Clin Exp Pediatr. 2002;45(9):1170-1174.   Published online September 15, 2002
Centrinuclear myopathy, an uncommon condition, is one of the congenital myopathies. It is characterized by the presence of central nuclei of muscle cells which can be detected on electronmicroscopy. It is believed to arise as a result of maturational arrest with persistence of microtubes postnatally. We report a boy with generalized hypotonia and muscle weakness who was diagnosed as centrinuclear...
A Case of Nonspecific Interstitial Pneumonia in a Child
Tae Wan Kim, Dae-Hyun Lym, Jung Hee Kim, Byong Kwan Son, Hye-Seung Han, Young Kyu Shin
Clin Exp Pediatr. 2002;45(4):529-534.   Published online April 15, 2002
Department of Pediatrics†, College of Medicine, Korea University, Seoul, Korea Interstitial pneumonia is a heterogenous group of inflammatory and fibrosing lesions that manifest themselves as infiltrative lung disease. Of these, nonspecific interstitial pneumonia is characterized as a variable degree of interstitial inflammation with or without fibrosis and is distinguished from usual interstitial pneumonia and desquamative interstitial pneumonia, histologically. The influx of...
A Case of Partial DiGeorge Syndrome in Prematurity
Tae Jung Sung, Eun Young Ko, Dal Hyon Kim, Ji Eun Oh, Young Se Kwon, Dae Hyun Lim, Byong Kwan Son
Clin Exp Pediatr. 2002;45(3):383-389.   Published online March 15, 2002
We experienced a case of partial DiGeorge syndrome in a 35＋5 week premature female infant presented with micrognathia, fish-shaped mouth, beaked nose, nasal regurgitation, obstructive sleep apnea, velopharyngeal insufficiency and late onset hypocalcemic seizures. The chromosome 22q11 microdeletion was found by the FISH method. The lab findings showed serum calcium level of 4.4 mg/dL, ionized calcium level of 0.49 mg/dL,...
Original Article
Usefulness of Chest High-Resolution CT in Patients with Chronic Cough Below 2 Years of Age
Myung Hyun Kim, Jung Hee Kim, Dae Hyun Lim, Byong Kwan Son, Kyung-Hee Lee
Clin Exp Pediatr. 2002;45(3):339-345.   Published online March 15, 2002
Purpose : The purpose of this study was to evaluate the clinical usefulness of chest high-resolution computed tomography(HRCT) in patients with chronic coughs or persistent wheezing with normal chest X-ray finding. Methods : We reviewed the charts, chest X-rays, and HRCT findings of patients with chronic coughs or persistent wheezing of less than 2 years of age. The records were sourced...
The Prevalence of Obesity and Underweight in Adolescents in Incheon Area and the Relationship between Serum Cholesterol Level and Obesity
Myung Hyun Kim, Tae Wan Kim, Young Jin Hong, Byong Kwan Son, Soo Hwan Pai, Kyung Ja Chang, Soon Ki Kim
Clin Exp Pediatr. 2002;45(2):174-182.   Published online February 15, 2002
Purpose : The purpose of this study was to investigate the prevalence of obese and underweight adolescents in Incheon area and to examine the relationship between serum cholesterol level and obesity, then to assess the nutritional condition of adolescents. Methods : With a questionnaire regarding their demographic characteristics, blood samples were obtained from apparently healthy students aged 12 to 24 years...
Study on the Interrelationship of Air Pollution and Respiratory Diseases in Inchon City Via Children Who Visited the Emergency Room of Inha University Hospital
Hyun Choi, Dae Hyun Lim, Jung Hee Kim, Byong Kwan Son, Jong Whan Lim, Youn Chol Hong
Clin Exp Pediatr. 2000;43(10):1372-1379.   Published online October 15, 2000
Purpose : It is generally accepted that air pollution can cause acute respiratory diseases. This study assessed the relationship between air pollution and development of pediatric respiratory diseases in Inchon city. Methods : We studied a number of pediatric patients who developed respiratory diseases such as bronchial asthma, bronchiolitis, URI, bronchitis and pneumonia and visited the Inha University Hospital emergency room...
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