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Case Report
Massive pulmonary hemorrhage in enterovirus 71-infected hand, foot, and mouth disease
Dong Seong Lee, Young Il Lee, Jeong Bae Ahn, Mi Jin Kim, Jae Hyun Kim, Nam Hee Kim, Jong Hee Hwang, Dong Wook Kim, Chong Guk Lee, Tae Won Song
Clin Exp Pediatr. 2015;58(3):112-115.   Published online March 20, 2015

Hand, foot, and mouth disease (HFMD) is an acute, mostly self-limiting infection. Patients usually recover without any sequelae. However, a few cases are life threatening, especially those caused by enterovirus 71 (EV71). A 12-month-old boy was admitted to a primary hospital with high fever and vesicular lesions of the mouth, hands, and feet. After 3 days, he experienced 3 seizure...

Original Article
Study on the neurodevelopmental predictors for the results of the Bayley Scales of Infant Development II in high-risk neonates
Mi Kyeong Woo, Dong Wook Kim, Kyoung Huh, Gyu Hong Shim, Myoung Jae Chey
Clin Exp Pediatr. 2009;52(11):1221-1227.   Published online November 15, 2009
Purpose : To identify the risk factors for poor neurodevelopmental outcomes in high-risk neonates. Methods : We studied 94 infants admitted to the neonatal intensive care unit at the Sanggye Paik Hospital between January 2002 and November 2005 and evaluated the follow-up data. The following events were considered as risk factors: ≤32 weeks of gestation, very low birth weight, Apgar scores...
Mediating effect of perceived stigma against epilepsy on quality of life among parents with epileptic child
Nho Eun Kim, Sung Min Cho, Dong Wook Kim
Clin Exp Pediatr. 2009;52(9):1005-1014.   Published online September 15, 2009

Purpose:Epilepsy of child may cause high level of psychosocial difficulties for parents including stigmatization and stress and therefore worsen their quality of life (QOL). The purpose of this study was to evaluate the mediating effect of perceived stigma against epilepsy on QOL among parents with epileptic child. Methods:Two hundred and sixty parents of epileptic child recruited from five separated university...
Complex febrile convulsions: A clinical study
Jeong Sic Kang, Sa-Ra Kim, Dong Wook Kim, Tae Won Song, Nam Hee Kim, Jong Hee Hwang, Jin Soo Moon, Chong Guk Lee
Clin Exp Pediatr. 2009;52(1):81-86.   Published online January 15, 2009
Purpose : Febrile convulsions are classified into simple or complex types, the latter being characterized by increased risk of recurrence and progression to epilepsy. This study aimed to delineate the clinical characteristics of complex febrile convulsions. Methods : Between January 2003 and December 2006, 550 children were diagnosed with febrile convulsions at the Department of Pediatrics, Ilsan Paik Hospital. Their...
Case Report
Steroid and enalapril therapy - possible cause of toxic epidermal necrolysis
Dong Wook Kim, Da Eun Jung, Ja Wook Koo
Clin Exp Pediatr. 2006;49(3):332-336.   Published online March 15, 2006
Toxic epidermal necrolysis (TEN) is a rare, acute and life-threatening cutaneous drug reaction. TEN is characterized by the sudden onset of extensive necrosis in the epidermis and frequent mucous membrane involvement. The pathogenesis has not yet been elucidated. In addition, no particular treatment for TEN has been established. We report a case of TEN in a 14-year-old-boy, which might have...
Original Article
Usefulness of serum procalcitonin test for the diagnosis of upper urinary tract infection in children
Dong Wook Kim, Ju Young Chung, Ja Wook Koo, Sang Woo Kim, Tae Hee Han
Clin Exp Pediatr. 2006;49(1):87-92.   Published online January 15, 2006
Purpose : It is difficult to make a distinction between lower urinary tract infection(UTI) and acute pyelonephritis(APN) during the acute phase of febrile UTI due to nonspecific clinical symptoms and laboratory findings, especially among young children. We measured the serum procalcitonin(PCT) in children with UTI to distinguish between acute pyelonephritis and lower UTI, and to determine the accuracy of PCT...
Etiology of Community-acquired Bacteremia in Healthy Children
Hyung Tae Kim, Hyun Oh Jang, Jin Soo Moon, Seung Yeon Nam, Dong Wook Kim, Chong Guk Lee, Chong Rae Cho
Clin Exp Pediatr. 2005;48(7):716-722.   Published online July 15, 2005
Purpose : A full view of the spectrum of all bacterial diseases in healthy children is essential to the establishment of public health priorities. Accurate information on the relative importance of the various pathogens in terms of the age of the affected patients, the site of infection and the case fatality rate are valuable to the clinician in choosing antimicrobial...
A Clinical Study on the Etiologies of Acute Seizures in Children Who Visited Emergency Department
Jung Il Cho, Dong Wook Kim, Hyun Oh Jang, Jin Soo Moon, Seung Yeon Nam, Seung Yeon Nam
Clin Exp Pediatr. 2004;47(12):1312-1318.   Published online December 15, 2004
Purpose : Although it is important to know the etiologies of childhood seizures according to age, clinical studies on this topic have been few. The present study was therefore designed to investigate the causes of acute childhood seizures. We hope this study will be helpful in the diagnosis and management of children with seizures. Methods : This study was retrospectively undertaken...
A Clinical Study on Benign Convulsions with Mild Gastroenteritis
Jung Il Cho, Dong Wook Kim, Hyun Oh Jang, Jin Soo Moon, Seung Yeon Nam, Chong Guk Lee
Clin Exp Pediatr. 2004;47(12):1306-1311.   Published online December 15, 2004
Purpose : 'Benign convulsions with mild gastroenteritis(BCwMG)' is afebrile seizures associated with gastroenteritis without dehydration or electrolyte imbalance in young children aged almost 6 months to 3 years. Because seizures can occur repeatedly, patients can be misdiagnosed with epilepsy. Therefore, understanding the characteristics of this disease is thought to be important. This study was carried out to investigate the clinical...
Medical Lecture Course
Antiepileptic Mechanisms of the Ketogenic Diet
Dong Wook Kim
Clin Exp Pediatr. 2001;44(3):297-302.   Published online March 15, 2001
Original Article
Cardiovascular Effects of Growth Hormone Treatment in Idiopathic Short Stature
Hyang Ok Woo, Dong Wook Kim
Clin Exp Pediatr. 1997;40(8):1149-1155.   Published online August 15, 1997
Purpose : An excess of GH causes various problems within the cardiovascular system including cardiac hypertrophy and abnormalities of left ventricle(LV) function. To evaluate the cardiovascular effects due to GH treatment in idiopathic short stature (ISS), we measured the cardiovascular function. Methods : Twenty-two echocardiographic studies were performed in ISS who were admitted from Jan. 1994 through Jul. 1996, and they were divided into two...
Case Report
Departments of Neurosurgery, Gyeongsang National University, College of Medicine, Chinju, Korea
Jae Young Lim, Young Kyu Park, Eun Sang Kim, Dong Wook Kim
Clin Exp Pediatr. 1997;40(4):555-558.   Published online April 15, 1997
Spinal-cord astrocytomas are rare, comprising only 1% of all primary central nervous system tumors. Malignant astrocytomas grade III and IV account for only 7.5% of intramedullary spinal gliomas occurring in all age groups and for as few as 1.2% of primary intramedullary tumors in children. The frequency of primary intramedullary with intracranial metastasis is relatively rare in childhood and such...
Original Article
A Study on thePredisposing Factors to Complex Febrile Convulsion
Ge Woo Yi, Dong Wook Kim
Clin Exp Pediatr. 1997;40(2):225-232.   Published online February 15, 1997
Purpose : Febrile convulsion is classified as simple or complex type, the latter being characterized by frequent recurrence of febrile convulsion itself and progression to epilepsy. This study was performed to seek the predisposing factors to complex febrile convulsion. Methods : This study was retrospectively undertaken to review medicalrecords of 472 children under 15 years of age with febrile convulsions, who were...
A Clinical Study on the Causes of Childhood Seizures According to the Age
Dong Wook Kim
Clin Exp Pediatr. 1996;39(12):1745-1752.   Published online December 15, 1996
Purpose : Although it is important to know the causes of childhood seizures according to the age, the clinical studies on this topic are rare in Korea. So, I would like to perform this clinical study to evaluate the frequencies of the age-related seizure causes in children. Methods : This study was retrospectively undertaken to evaluate the age and sex distribution,...
Clinical Study on Chronic Granulomatous Disease (CGD) -Occurrence in Siblings-
Yong Hoon Jun, Sung Won Yang, Dong Wook Kim, Hoan Jong Lee, Joong Gon Kim
Clin Exp Pediatr. 1994;37(6):794-803.   Published online June 15, 1994
To analyse the age of onset, etiologic microorgnisms, clinical manifestations, managements and genetic variation of chronic granulomatous disease, the authors reviewed four patients who were diagnosed as CGD at Department of Pediatrics, Seoul National Univesity Children's Hospital. They were siblings in relationship-two of them were brothers, the others wete brother-sister. The results were as follows; 1) Initial manifestations developed within 1...
Neurologic Complications after Open-Heart Surgery in Children
Tae Sung Ko, Ki Joong Kim, Dong Wook Kim, Yong Seung Hwang, Yong Jin Kim, Joon Ryang Rho
Clin Exp Pediatr. 1993;36(9):1245-1257.   Published online September 15, 1993
Neurologic complications after open-heart surgery are not only relatively common but also often fatal. In order to know the clinical characteristics and carsative risk factors, we carried out the retrospective study on 655 patients who had been admitted and undergone OHS at Seoul National University Children's Hospital during 2-year period from July 1990 to June 1992. The results...
The Effectf Zonisamide in Children with Refractory Epilepsies
Ki Joong Kim, Soo Ahn Chae, Tae Sung Ko, Dong Wook Kim, Yong Seung Hwang
Clin Exp Pediatr. 1993;36(8):1139-1145.   Published online August 15, 1993
Zonisamide was amministered to 20 patients with refractory epileptic seizures. The mean duration of the administration was 6 months, and the mean dosage was 7.2mg/kg/day. The efficacy of zonisamide was rated remarkable in 15% of the cases, improvement in 40%, and no change in 45%. The response rates of zonisamide were 62.5% for myoclonic seizures, 50% for tonic-clonic seizures, 80% for...
Case Report
Three Cases of Post-transfusion Hepatitis C
Kyung Un No, Ho Seong Kim, Ji Won Choi, Dong Wook Kim, Cheol Ho Jang, Beom Su Park, Jeong Kee Seo, Gyeong Hoon Kang, Je Geun Chi
Clin Exp Pediatr. 1992;35(9):1255-1262.   Published online September 15, 1992
Hepatitis C virus has been known to be the main cause of post-transfusion non-A, non-B hepatitis. The authors experienced three cases of hepatitis C. All were associated with blood transfusions. They had no specific symptoms, and the levels of aminotransferases were markedly elevated and showed severe fluctuations in two cases. Anti-HCV tested two or three times were all positive, and...
A Case of Hypomelanosis of Ito Accompanying Turner Syndrome
Kyung Un No, Dong Wook Kim, Dong Joo Shin, Hyung Ro Moon
Clin Exp Pediatr. 1992;35(8):1157-1163.   Published online August 15, 1992
Hypomelanosis of Ito has been known to show the characteristic hypopigmentation of the skin over the trunk and the extremities following Blaschko lines, and to accompany abnormalities of the central nervous system, the skeletal system, the eye and so on. Lately, a variety of chromosomal anomalies, especially mosaicism, have been reported in association with hypomelanosis of Ito, which is believed...
Four Cases of Massive Infiltrating Congenital Cystic Hygroma Managed by Bleomycin Sclerosing Therapy
Hyun Kwack, Dong Wook Kim, Kyung Woon No, Jun Heo, Sun Young Kim, Young Pyo Jang, Jung-Hwan Choi, Chong Ku Yun, Seong En Jung, Gui Won Park, Woo Gi Kim, In Won Kim, Kyung Mo Yeon
Clin Exp Pediatr. 1992;35(8):1148-1156.   Published online August 15, 1992
Cystic hygroma is a true, benign, congenital multi-cystic tumor. It is thought to be arised from failure of the lymphatic system to communicate with the venous system. Frequently it occurs at birth, and it is found most commonly in the neck as painless and fluctuant mass. For many years, surgical excision has been considered as the treatment of choice. However, excision...
Transfusion-Acquired Cytomegalovirus Infections in Two Premature Infants
Dong Wook Kim, Kyung Un No, Mi Jung Kim, Soon Mee Park, Hee Sup Kim, Young Pyo Chang, Hoan Jong Lee, Jung-Hwan Choi, Chong Ku Yun, Je Geun Chi
Clin Exp Pediatr. 1992;35(8):1141-1147.   Published online August 15, 1992
Transfusion-acquired perinatal cytomegalovirus (CMV) infection can cause significant morbidity and mortality, particularly in premature infants with a birth wight of less than 1,500 gm. This recognizable syndrome consisted of deterioration of respiratory function, hepatosplenogaly, unusual gray pallor with disturbing septic appearance, lymphocytosis, thrombocytopenia and hemolytic anemia. We experienced transfusion-acquired CMV infections in 2 premature infants with a birth weight of...
Original Article
Cytomegalovirus Infection in Children: The Significance of CMV Specific IgM Antibody Test and Virus Isolation in the Urine
Dong Wook Kim, Hyun Kwack, Seong Hee Jang, I Seok Kang, Hoan Jong Lee, Jung-Hwan Choi, Jeong Kee Seo, Chong Ku Yun
Clin Exp Pediatr. 1992;35(7):890-901.   Published online July 15, 1992
The clinical pictures of 44 children with IgM antibody to CMV (cytomegalovirus) by ELISA(enzyme linked immunosorbent assay) were reviewed retrospectively, and the significance of serum CMV specific IgM antibody and virus isolation in the urine was analyzed. Age of the patients with IgM antibody to CMV ranged from 23 days to 8 years 7 months, and median age was 2 months....
Case Report
A Case of Annular Pancreas.
Dong Wook Kim, Sang Taik Lee, Soo Yong Kim, Jeong Kwon Lee, Young Dae Kwon
Clin Exp Pediatr. 1986;29(10):1147-1151.   Published online October 31, 1986
Annular pancreas is unusual cause of duodenal obstruction in neonatal period in which, pancreatic tissue forms a partial obstruction or complete ring encircling the duodenum. It develops as a result of malrotation or overgrowth of ventral anlage of the embryonic pancreas and frequently associated with other congenital anomalies. Since the first description by Tiedman in 1818 and first sucessful (surgical treatmetn) by Vidal...
4 Cases of Progressive Muscular Dystrophy.
Jung Hee Kim, Dong Wook Kim, Dae Deok Ahn, Jung Kwon Lee, Yoon Ja Kim
Clin Exp Pediatr. 1985;28(12):1225-1230.   Published online December 31, 1985
Progressive muscular dystropy is a genetically determined disorder characterized by-progressive weakness and wasting of skeletal muscles. The etiology of muscular dystropy is unknown, and no form of phamacological treatment is considered effective. The authors report 4 cases of P.M.D., of which 2 cases occured in a family and 2 cases were developed sporadically. They were diagnosed by clinical findings, serum,...
Original Article
Lipid Composition of Serum HDL and Fatty Acid Composition of Serum Cholesteryl Esters in Newborn.
Jung Hee Kim, Dong Wook Kim, Dae Deok Ahn, Jung Kwon Lee, Yoon Ja Kim, Jung Chull Kim, Tai Ho Chung
Clin Exp Pediatr. 1985;28(12):1190-1195.   Published online December 31, 1985
Lipid consumption in early life has been implicated with atherosclerosis in later life. It has been also claimed that lipids contents of serum in early life would reflect coronary atherosclerosis in later life. Present study has undertaken to look for the composition of serum HDL and fatty acid composition of serum cholesteryl esters in newborns. Levels of high density lipoprotein...