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Original Article
Carriage and Antimicrobial Susceptibility of Haemophilus influenzae Isolated from Oropharynges of Children
Kyung Hyo Kim, Kyoung Ah Lim, Il Tae Whang, Young Mi Hong, Eun Sook Kang, Ki Sook Hong
Clin Exp Pediatr. 2001;44(5):509-516.   Published online May 15, 2001
Purpose : Haemophilus influenzae, one of the normal flora of the upper respiratory tract, can cause such infections as otitis, sinusitis, pneumonia, and meningitis in children. The oropharyngeal flora has therefore mainly been analyzed as a reservoir for pathogens. This study was performed to reveal the colonization rate of H. influenzae in the upper respiratory tract, their biotypes, their antimicrobial...
Etiology and Clinical Features of Severe Acute Viral Lower Respiratory Tract Infections in Children
Noo Lee Jeon, Bong Seong Kim, Yoo Kyum Kim, Soo-Jong Hong
Clin Exp Pediatr. 2000;43(12):1558-1568.   Published online December 15, 2000
Purpose : The purpose of the study is to understand the etiology and clinical features of severe acute viral lower respiratory tract infection(LRI), especially in conjunction with the use of ventilator care and/or with bronchiolitis obliterans. Methods : Etiologic agents and clinical features of severe acute viral LRI were studied from July 1998 through June 1999 in children at Asan Medical...
Case Report
A Case of Septic Arthritis due to Haemophilus influenzae associated with Atypical Kawasaki Disease
Sun Mi Yang, Jun Yun, Hea Kyoung Lee, Young Hee Yu, Hyun Sook Lee
Clin Exp Pediatr. 1999;42(10):1441-1445.   Published online October 15, 1999
We report a case of septic arthritis due to H. influenzae associated with atypical Kawasaki disease. A 2-year-old boy was admitted to our orthopedic department due to limping gait of the right leg. CT finding of right hip joint revealed fluid collection. He was diagnosed as transient synovitis and septic arthritis. He was treated with antibiotics, but no incision nor...
Original Article
Immunogenicity of Haemophilus influenzae PRP-D Conjugate Vaccine in Korean Infants
Soo Young Choi, Hee Taek Kim, Yeon Woo Kim, Yun Jong Kang, Yeon Chung Chung, Jin Keun Chang, Hoan Jong Lee
Clin Exp Pediatr. 1999;42(6):771-777.   Published online June 15, 1999
Purpose : Infection by Haemophilus influenzae Type B(Hib) occurs most often in infants and children who are 5 years old and less. The incidence is highest around 6 months of age, and then decreases thereafter as infants gain natural immunity. Hi PRP-D conjugate vaccine is poorly immunogenic in infants. However, immunogenicity PRP-D vaccine in Korean infants is unknown. This...
A Clinical Analysis on Acute Lower Respiratory Tract Infections in Children Caused by Influenza Virus in Children
Kiehl Hyung Lee, Woo Kyung Kim, Mi Ran Kim, Dug Ha Kim, Hae Ran Lee, Chong Young Park, Kyu Man Lee
Clin Exp Pediatr. 1998;41(12):1623-1631.   Published online December 15, 1998
Purpose : Although annual epidemics occur, there are only a few clinical studies on influenza in Korea. We evaluated the epidemic and clinical features of acute lower respiratory tract infections in children by influenza virus. Methods : From Feb., 1995 to July, 1997, influenza virus isolations and clinical review were performed on hospitalized children with acute lower respiratory tract infections at...
Epidemiologic and Clinical Feature of Acute Lower Respiratory Tract Infections by Respiratory Syncytial Virus and Parainfluenza Virus in Children
Jeoung Jin Lee, Hyeon Seon Park, Mi Ran Kim, Dug Ha Kim, Hae Ran Lee, Chong Young Park, Woo Kap Chung, Kyu Man Lee
Clin Exp Pediatr. 1997;40(8):1071-1080.   Published online August 15, 1997
Purpose : This is to analyze epidemic and clinical features of acute respiratory tract infections(ALRTI) by respiratory syncytial virus(RSV) and parainfluenza virus(PIV), which are considered to be the major respiratory pathogens in children. Methods : Nasopharyngeal aspirates were collected from 515 patients with ALRTI hospitalized at Hangang Sacred Heart Hospital between Apr. ’94 and Oct. ’96. Nasopharyngeal aspirates were inoculated to...
Effect of Meconium Components on Haemophilus influenzae Growth by Surfactan
Min Hee Kim, Sang In Chung
Clin Exp Pediatr. 1997;40(3):327-335.   Published online March 15, 1997
Purpose : Meconium is a complex mixture with a potential variable composition, it is difficulty to determine which components of meconium are responsible for the surfactant inhibition. We previous reported that Surfactant-TA and Exosurf almost completely inhibited the growth of Haemophilus influenzae at the concentration of 100% without apparent difference in the efficiency.In this study, We have determined the effect of...
Changes of Anti-H.influenzae Type b IgG in the Sera of Korean Infants and Children after Birt
Jong Man Park, Keoung Hie Moon, Kyung Mee Lee, Sun Jun Kim, Soo Chul Cho, Jung Soo Kim
Clin Exp Pediatr. 1997;40(2):181-188.   Published online February 15, 1997
Purpose : Most of invasive Haemophilus influenzae diseases occur in children under 5 years of age, and are due almost exclusively to type b strain. Although antibodies to several surface antigens of H.influenzae play a role in conferring immunity, antibody to the type b capsular polysaccharide appeared to have the most important protective functions. However, the antibody response to vaccines or natural...
Etiology and Clinical Features of Acute Viral Lower Respiratory Tract Infection in Apparently Healthy children
Song Yi Nah, Jeong Yun Hong, Eun Hwa Choi, Hoan Jong Lee
Clin Exp Pediatr. 1996;39(12):1690-1699.   Published online December 15, 1996
Purpose : Acute lower respiratory tract infections(LRIs) are an important cause of pediatric morbidity and mortality. Causes of acute LRI in infants and children include bacteria, mycoplasma and respiratory viruses. Understanding of the epidemiology, etiology and clinical features of acute viral LRI is essential to improve the methods of prevention, diagnosis and management of these infections. Methods : Viral etiologic agents and clinical features of...
Case Report
A case of Neurologic Sequelae and a Case of Peripheral Gangrene of Extremities Associated with Haemophilus influenzae Type b Meningitis
Clin Exp Pediatr. 1995;38(10):1429.   Published online October 15, 1995
Haemophilus influenzae type b(Hib) is one of the most common organisms causing bacterial meningitis in children aged between 2 months and 6 years. Since introduction of Hib vaccination, the mortality from Hib meningitis has fallen, but major neurologic sequelae, ie, mental retardation, seizure, blindness, and persistent motor deficits, are serious problems. Cerebral infarction was rarely complicated during the course of meninigitis...
Original Article
Natural Anti-PRP Antibody Levels to Haemophilus Influenzae Type b(Hib) and Changes of Antibody Levels after Three Doses of Vacination
Eun Sun Yoo, Eun Ae Park, Gyoung Hee Kim
Clin Exp Pediatr. 1995;38(9):1201-1209.   Published online September 15, 1995
Purpose : The Haemophilus influenzae type b(Hib) was the most common cause of meningitis and invasive bacterial disease mainly in children 2 months to 5 years old in the United States. The conjugated Hib vaccines have recently been licensed by the US Food and Drug Administration for routine use in infants beginning at 2 months of age, and the Infectious...
Influenza Epidemic in the Pediatric Patients in Seoul 1991
Hyun Mi Kim, Se Ho Oh, Eun Young Cho, Ki Soo Kim, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Young Suhn Kim, Kee Duk Park
Clin Exp Pediatr. 1993;36(3):379-385.   Published online March 15, 1993
Influenza virus culture was performed in 149 patients with influenza-like illness who were admitted or visited to the Department of Pediatrics, Asan Medical Center from january 1991 to March,1991. The results were as follows : 1) Of the total 149 patients, influenza virus were isolated in the 15 cases. : 15 isolates were characterized by the WHO Collaborating Center for influenza : 7...
A Case of Subdural Empyema Complicating Hemophilus Influenzae Meningitis.
Myung Sun Oh, Nan Kyung Kim, Sae Yoo Jung, Soon Ung Kang, Jung Kyou Kim, Byong Kwan Son
Clin Exp Pediatr. 1990;33(8):1129-1133.   Published online August 31, 1990
We have experienced Hemophilus influenzae meningitis complicated by subdural empyema, which was confirmed by computerized tomography and subdural tapping. The patient was 5-month-old female who was admitted with high fever and generalized siezure. Hemophilus influenzae meningitis was confirmed by the culture of spinal fluid. The organism was sensitive to the ampicillin but the clinical course was not satisfactory with persisting high fever because of complication....
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