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Original Article
The Study of Distribution of HI Antibody Titers Aganist Japanese Encephalitis Virus Among Children in Seoul
Jin A Kim, Tae Sung Ko, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Hae Wol Cho
Clin Exp Pediatr. 1996;39(2):230-237.   Published online February 15, 1996
Purpose : Incidence of Japanese encephalitis has been markedly decreased, but this disease is known to be high and lethal in the young age group. This study was designed to find out the HI antibody titers and associated factors of Japanese encephalitis of children in Seoul, and to establish the plan of vaccination. Methods : The survey was conducted from the...
Prevalence and Its Changes of Hepatitis B Viral Markers from 1988 to 1993 in Korean Children
Jae Geon Sim, Jeong Kee Seo, Seong Jae Suh
Clin Exp Pediatr. 1995;38(11):1535-1539.   Published online November 15, 1995
Purpose : Hepatitis B infection is prevalent in Korea and active immunization of Hepatitis B has been proceeded intensively during the last decade. This study was designed to evaluate the changes of the prevalence of hepatitis B surface antigen (HBsAg) and that of antibody (HBsAb) in Korean children from 1988 to 1993. We can estimate the prevalence and tendency of...
Antibody Response to Capsular Polysaccharide Vaccine of Streptococcal Pneumonia in Patients with Nephrotic Syndrom
Ji Young Choi, Jae Ho Lee
Clin Exp Pediatr. 1995;38(8):1107-1115.   Published online August 15, 1995
Purpose : Although the etiology and pathogenesis of child with nephrotic syndrome remains uncertain, it has been suggested from indirect evidence that this syndrome may represent deficiency in T-cell function and abnormal humoral immune response to antigens or immynoglobulin. Children with nephrotic syndrome are susceptible to pneumococcal infection. Now, we performed this study to evaluate pneumococcal anticapsular antibody concentration and...
Clinical Studies of Measles in Infancy - Emphasizing on Measles Specific IgG Antibody -
Jae Ho Lee, Shin Hye Moon
Clin Exp Pediatr. 1995;38(7):907-913.   Published online July 15, 1995
Purpose : This study was investigated the efficacy of maternal measles specific IgG antibody and the optimal age for measles vaccination in susceptable infant during epidemics Methods : We evaluated the clinical manifestations and complications of 50 measles infants who were clinically and serologically diagnosed as measles and had not been vaccinated acco-rding to the presense of measles specific IgG antibody...
Epidemiology and Vaccine Efficacy of Measles During the 1993 measles Epidemic
Soon Ki Kim, Jong Woon Choi, Byong Kwan Son, Seung Nam Park, Churl Young Chung, Young Min Ahn, Chong Young Park, Ki Yang Ryoo, Woo Kap Chung, Hoan Jong Lee
Clin Exp Pediatr. 1995;38(6):778-785.   Published online June 15, 1995
Purpose : Because of increased measles incidence in Korea during 1993 and the recent finding of genomic differences between vaccine virus and contemporary wild measles viruses, we conducted a measles vaccine efficacy study involving children ages 1 to 5 yeark, with the demographic analysis of patients brought to the hospitals during measles outbreak that had occurred 1993 in Seoul and...
The Values of Tetanus Toxoid Specific IgG Immunoglobulins in Children
Young Kwan Kim, Young Mo Son
Clin Exp Pediatr. 1995;38(3):306-310.   Published online March 15, 1995
Purpose : Tetanus toxoid specific IgG titers were measured in 76 cases on children ranging from neonates to 18 yr old adolescents according to the frequency of DPT vaccination. Methods : The Enzyquick tetanus Kit was used to measure tetanus toxoid specific IgG titers by the ELISA method. Results : 1) In infants less than 2 months-olg, the mean tetanus toxoid specific...
Tuberculin Skin Test and Measles Vaccination
Mi Sung Chung, Young Mi Kim, Hyung Ja Park, Shinna Kim
Clin Exp Pediatr. 1993;36(4):537-542.   Published online April 15, 1993
Although the incidence of tuberculosis in Korea in general has declined in recent years, it remains an important health problem, especially in children. Inspite of the recent controversy over the necessity of tuberculin skin test prior to measles vaccination, this brief report shows 13.8% of positive skin test at 9 and 15 months of age at the time of measles...
Serological study to determine the optimum age for measles vaccination in Korea.
Gum Ja Lee, Kon Hee Lee, Hae Sun Yoon
Clin Exp Pediatr. 1991;34(9):1201-1210.   Published online September 30, 1991
In recent years, measles outbreak has involved a great population of cases in younger children. For this reason, we reevaluated the conventional vaccination schedule by measuring measles antibody level. Two groups totalling 244 children were included in the study. The non-measles group consisted of 133 children who visited or were admitted to our hospital during the 7 month period from Jan. 1990 through July 1990...
A study on current immunization status attending an above-middle from class primary school in Seoul.
Jae Won Oh, Sung Lae Park, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 1991;34(9):1187-1200.   Published online September 30, 1991
1. Purpose and Methodology The purpose of this survey was to estimate the current immunization status of Korean children by the information gathered by questionnaire distibuted to the parents of all children attending an above-middle class private primary school in Seoul and thereby analizing various factors closely related to the vaccination program as currently administered in Korea. The survey has been conducted by obtaining written answers...
The Change of Anti-HBs Titer after Hepatitis B Vaccination in Newborn.
Ji Hye Kang, Young Mi Hong, Seung Joo Lee
Clin Exp Pediatr. 1990;33(5):598-605.   Published online May 31, 1990
Hepatitis B vaccination is an accepted preventive measure for all newborn as well as the risk group. However, there is some uncertainty about the persistence of anti-HBs and the timing of booster vaccination. We studied anti-HBs titer, positive rate and minimum protective rate in relation to time interval after the third vaccination in 102 infants bom to HBsAg negative mother (Group I) and 52...
Changes of Specific Immunogloblins Against Dihperia Toxoid After DPT Vaccination.
Byung Sook Park, Byung An Shim, Kyung Jin Shin, Soo Chul Cho, Jung Soo Kim
Clin Exp Pediatr. 1988;31(9):1126-1132.   Published online September 30, 1988
The present study was performed to define the humoral immune responses after DPT vaccination changes of diphteria specific IgG and IgM were evaluated suing ELISA method on 196 cases of 6 groups which were divided according to the frequency of DPT vaccination. Alum-precipitated diphtheria toxoid was used as antigen for ELISA. The results were as follows; 1) IgG was mainly involed in humoral immune responses against...
Specific Immunoglobulin Responses Against Tetanus Toxoid after DPT Vaccination.
Kyung Jin Shin, Sng Nam Chun, Heon Seob Song, Dae Yeal Lee, Jung Soo Kim
Clin Exp Pediatr. 1987;30(6):625-632.   Published online June 30, 1987
DPT vaccination has successfully been applied to the prevention of tetanus infection. Edsall (1949) reported the presence of serum tetanus antitoxin after tetanus toxoid immunization. Gill et al (1983) also demonstrated that the values of tetanus specific IgM were increased on neonates after maternal tetanus toxiod immunization. The present study was performed to define the humoral immune responses after DPT vaccination. Changes of tetanus specific...
Evaluation of Antibody Formation After Hepatitis B Vaccination in Children.
Pyung Kil Kim, Ho Taek Kim, Kyu Earn Kim, Kyung Soon Song
Clin Exp Pediatr. 1986;29(10):1072-1079.   Published online October 31, 1986
Hepatitis B virus infection is a serious problem in many countries, especially Africa, Southeast Asia and Korea. As we know, vaccination against hepatitis B virus is the most effective method to prevent hepatitis B and the rate of anti-HBs formation after hepatitis B vaccination is known to be 91 〜99%. We studied the titer of anti-HBs after 3 times of...
A Clinical Observation of Measles: Influence of measles Vaccination.
Jung Sue Suh
Clin Exp Pediatr. 1982;25(8):816-823.   Published online August 31, 1982
The clinical observations and comparative studies according to vaccination was performed on 237 cases of measles that were treated at the pediatric ward and out patient clinic of Busan National University Hospital during 5 year period from Jan. 1976 to Dec. 1980. The results were summarized as follows : 1.The incidence of measles was most frequently in 1977 and a...
A Clinical Study on Anaphylactoid Purpura.
T K Yoon, T H Lee, S M Shin, S J Lee
Clin Exp Pediatr. 1981;24(12):1185-1192.   Published online December 15, 1981
Anaphylactoid purpura is a common disease in childhood and manifests variable clinical features including hepatomegaly. We analyzed 35 children who were admitted and diagnosed as anaphylactoid purpura at Soon Chun Hyang hospital during the periods of 5 years from September, 1975 to August 1980. The results were as follows: 1)It more frequently affected male than female, in the ratio...
Clinical Review of Tuberculosis in Childhood.
Hye Ran Lee, Woon Sik Kim, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1981;24(4):319-328.   Published online April 15, 1981
A clinical review was made on 152 cases of tuberculosis who had been admitted at pediatric department, National Medical Center during the period of 10 years from January, 1969 to December, 1978. The following results were obtained. 1.There noted no difference of annual incidence throughout the study years. 2. The highest age incidence was in the group of 1 to 3 years...
A Clinical Study of Meales: in relation to measles vaccination.
Ra Lee, Kyu Youp Kim, Soo Jee Moon, Chang Moo Park
Clin Exp Pediatr. 1981;24(3):191-197.   Published online March 15, 1981
We made a clinical observation of 191 cases of measles at the pediatric department of Hanyang University Hospital during the period from May, 1972 to May, 1979. The results obtained were as follows: 1.The incidence of measles patients among the total pediatric patients was about 1% and the ratio of the unvaccinated and the vaccinated was 72 to 28. Recently, the...