Purpose : Childhood tuberculosis is often asymptomatic with low culture rate, but it may res-ult in serious complications via hematogenous spread. Therefore, this study was done to evalu-ate clinical features, laboratory findings in tuberculosis patients proved by culture. Methods : We reviewed retrospectively the medical records of 48 cases of proved tubercul-sosis at the department of Pediatrics, National Medical Center, during... |
Hemobilia caused by pancreatic disease is very rare. The most common cause is a splenic artery pseudoaneurysm caused by acute and chronic inflammation of the pancreas. We experienced a case regarding as hemobilia as a complication of chronic relapsing pancreatitis in a 14 year-old boy. He was admitted with chief complaints of abdominal pain and hematemesis. Two years prior to admission,... |
Purpose : Surgical excision has been the primary treatment for hepatoblastoma and hepatocellular carcinoma. However, at presentation, only one third of such tumors are surgically resectable. Without operation, the disease is fatal. Therefore, neoadjuvant chemotherapy has been introduced for conversion of the unresectable tumors into the resectable ones. We studied th e effects of chemotherapy for hepatic malignancy in children. Methods... |
Clinical analysis of 170 patients with childhood leukemia was made, who were admitted to the department o Pediatrics, Pusan Paik Hospital, Inje University, College of Medicine during 10 years from 1981 to 1990. The results were as follows: 1) The annual number of the patients with childhood leukemia was in the range of 6~25 cases. And the annual rate of the... |
Gastric adenocarcinoma in childhood is an extremely rare disease with poor prognosis. We experienced a case in which a 14 year old female patient who was admitted with complaints of abdominal pain, indigestion and obstipation. Her physical examination revealed positive Blumer's rectal shelf, positive ascitic fluid cytology and typical radiologic and endoscopic findings suggesting gartric adenocarcinoma. She showed symptomatic improvement... |
We report a cases of solid and papillary neoplasm of the pancreas, which is a rare pancreatic tumor. We described clinical characteristics, sonographic, computed tomographic and pathologic finding. The tumors had a smooth, enhanced capsule and variable internal architecture. The tumor was distributed tail of pancreas without local invasion. The origin of the tumor is probably from a multipotential stem... |
Medicine, Seoul, Korea Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea To study the clinical characteristics and treatment results of childhood soft tissue sarcoma, the retrospective study was performed on 67 patients with soft tissue sarcoma, experienced at the Department of Pediatrics, Seoul National University Hospital from January, 1982 to July, 1990. The... |
From January 1984 to June 1991, we studied testicular relapsed patients among 105 cases of acute lymphocytic leukemia in children who were admitted to the Department of Pediatrics and Yonse Cancer Center, Yonsei University Severance Hospital. The results were as follows: 1) 15 out of 105(14.4%) cases of acute lymphocytic leukemia were diagnosed as testicular relapse. According to the prevalence by the... |
Myelodysplastic syndrome is a heterogeneous disease complex which is basically a clonal disorder and has characteristics of cytopenia of one or more cell series in peripheral blood and of dyspoiesis of precurosirs in bone marrow. Since the nature of this disease in childhooh is very different from that in adults, retrospective clinical study was performed with 17 confirmed patients who... |
Rhabdomyosarcoma is a relatively common solid tumor in infants, children and adolescents, according for 4% to 8% of malignant disease in children less than 15 years old. Use of a multimodal approach to treatment has resulted in a dramatic improvement. Yonsei Cancer Center in Korea, since it's establishment in 1975, has been a state of multimodal approach. Thirty-seven cases of childhood... |
Carcinomas in childhood differ from those in adults in their frequency, histologic type, and distribution of primary sites. In children, carcinomas are rare and few series have been published containing sufficient mumbers of cases to permit a reliable account of the incidence and survival of children with carcinoma. During a 10-year period, 1982-1991, we observed 40 patients less than 16... |
The 18 cases of primary gastrointestinal lymphoma patients admitted to the Department of Pediatrics and Yonsei Cancer Center, College of Medicine, Yonsei University, during 15 years from January, 1975 to December, 1989 were reviewed on the bases of clinical characteristics, treatment, and survival rates. The results were summarized as follows; 1) The age of patients ranged from 3 years to 14 years,... |
This study was designed to evaluate the prevalence and significant features of 3,234 pediatric accidental patients who visited emergency room during 6 years period from January 1982 to December 1987. 1) The accidental pediatric patients were 26.7% of total pediatric patients who visited emergency room The frequency of Childhood accidents was increased in later 2 years period(34.7%) compared with the early... |
We have experienced a case of transient erythroblastopenia of childhood in a 7 years old male patient who was diagnosed by bone marrow aspiration. His hematologic improvement occurred spontaneously. A brief review of related literature was done. |
Leukemia is a neoplasm arising from the malignant transformation of hematopoietic cells. The incidence data of leukemia have not been available for Korean as a whole. The present study was therefore undertaken in order to estimate the incidence of childhood leukemia among Korean. The study population of this investigation was the beneficiaries of the Korea Medical Insurance Corporation(KMIC) during the period... |
Renal biopsy is indicated in nephrotic syndrome when histopathologic types other than minimal change pattern or the secondary nephrotic syndrome are suspected. But renal biopsy in children has some limitation because of the technical problem. In order to assess the clinicopathologic correlation and to re-evaluate the biopsy indication, the clinical manifestations and histopathologic types were analyzed statisically on the 86 cases of childhood nephrotic syndrome... |
Six pediatric patients who were diagnosed as malignant Schwannoma and treated at Seoul National University Children’s Hospital from Aug. 1981 to Jun. 1990 were reviewed. Mean age was 11 years and 1 month and all cases except one were over 10 years old. Of six cases, three (50%) were associated with von Recklinghausen’s disease. Overall male to female ratio was 1 : 2. In... |
The diagnosis and management of gastrointestinal tract hemorrhage in infants and children have been changed dramatically over the past decade. Although previous reviews of this subject have suggested that the cause of gastrointestinal tract bleeding may remain obscure in many patients, recent experience indicates that this is now uncommon. This advance is largely a result of the widespread and now routine application of fiberoptic... |
Fourteen patients who had developed a chylothorax in childhood during a ten year period, from Jan. 1979 to July 1989, were reviewed by their hospital records. The chylothoraces occurred most frequently as complications of cardiothoracic surgeries in eight patients(57%). Four cases followed extrapericardial operations such as ligation of PDA and take-down of Blalock-Taussig shunt, and four cases followed intrapericardial operations such as corrective operations... |
Immunoglobulin (Ig) and T cell receptor 0 chain (TcR分) gene rearrangements can be used as ”genetic marker” of lineage and clonality in the study of lymphoproliferative disease. We analyzed genomic DNA of the bone marrow mononuclear cells from twenty six patients with acute leukemia in children. The patients were seventeen cases of acute lymphocytic leukmia (ALL), seven cases of acute nonlymphocytic leukemia (ANL) and... |
A clinical study was done on 96 cases of goiter in children which were diagnosed at pediatric department of Kwangju Christian Hospital during the period form January 1985 to December 1988. The observed clinical data were summarized as follows: 1) Preponderately femalels were affected with the sex ratio of 1:6.7. The majority of cases (78.2%) were around puberty. 2) On physical examination, 59 cases (85.5%) were found... |
35 childhood insulin-dependent (Typel) diabetes mellitus were typed for HLA and examined for presence of islet cell antibody and level of C-peptide. The following results were obtained: 1) HLA types were present as follows; HLA A24 (9) in 58%, DR3 in 38% and DR4 in 62%. This was slightly higher than the Korean population of 38%, 7% and 48% but there was no significant difference. 2) When... |
We carried out a stastical & clinical analysis on 2,593 cases of childhood accidents visiting emergancy room of National Medical Center during last 5 years, from Jan. 1, 1984 to Dec. 31, 1988. The results were as follows: 1) The total percent of accidents among EMR visitors showed 6% increase in 1988 compared to that of in 1984 2) The most common type of accidents was trauma... |
The one-hundred-twenty-seven asthmatic children who were diagnosed and treated either through admission or through clinic visits at the Department of Pediatrics, Hanyang University Hospital from July 1987 to March 1989, were investigated for clinical patterns and epidemiologic correlations. The diagnosis of asthma was made by typical clinical history, physical findings and laboratory examina- tion. The results were as follows: 1) Sixty-three percent of the total population at... |
There had been total 165 cases of urinary tract infection who had been admitted to the ward of pediatrics, National Medical Center from ]an. 1986 to Sept. 1987. Among these, 80 cases had indication of radiologic evaluation; they were the first-documented urinary tract infection in male patients, the first documented urinary tract infection in female patients younger than 6 years of age,... |
Trichobezoar is one of the rare diseases, which usually occurs in teen.aged girl who has an emotional disturbance and history of trichophagia. We experienced a case of gastric trichobezoar in a 8 year old girl, who had colicky abdominal pain and movable epigastric mass with the history of trichophagia. Diagnosis was suspected by the history of trichophagia and movable epigastric mass and confirmed by... |
A retrospective study was performed on twenty-nine children, who had experienced infection one or more times, among the thirty-eight children diagnosed as leukemia at the Department of Pediatrics, Seoul National University Hospital, between January, 1984 and June, 1985, and followed up for more than three years. The results were as follows; 1) The age of patients ranged from I year 5 months to 14 years... |
Presently, an increasing incidence of Bronchial asthma in children is of concern to medical professionals. Worldwide data from surveys indicate a wide range for the prevalence of childhood asthma, it has been estimated that 5-10% of the young population. An epidemiological approach was used to test the prevalence of bronchial asthma out of all pediatric cases referred to the emergency room. 248 cases were selected... |
Although many papers about peptic ulcer disease in childhood has stated that the condition is increasing in incidence during the past several years, still the condition is not frequently recognized in childhood compared with the incidence in adults. Authors carried out the clinical analysis on 35 patients with peptic ulcer under the age of 15 years who were admitted to pediatric department of Dong... |
From Jan,M 1983 to Dec., 1986, we studied total 2386 microorganisms which were isolated from various clinical specimens of admitted patients and out-patients in the department of pediatrics, NMC, and their antimicrobial susceptibilities were compared. The results were as follows; 1) The most frequently isolated stains from various specimens were S. aureus from throat, E. coli from urine, Shigella from stool, S. aureus from blood,... |