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Case Report
A Case of Chronic Pancreatitis with Pancreatic Stones in Childhood
Young Kyoo Shin, Chan Wook Woo, Kee Hyoung Lee, Young Chang Tockgo, Chang Duck Kim
Clin Exp Pediatr. 1995;38(7):1012-1017.   Published online July 15, 1995
Chronic pancreatitis is a rare problem in childhood and sometimes shows pancreatic calcif-ication. The most common symptom is chronic recurrent upper abdominal pain, with waves of crampy pain that increase in severity, with or without associated nausea or vomiting. Although the diagnosis is made or considered infrequently hereditary or other metabolic factors, the cau-se remains largely idiopathic. Endoscopic retrograde cholangiopancreatography(ERCP)...
Original Article
Evaluation of Culture Proved Tuberculosis Patients
Eun Kyung Lee, Jae Yoon Kim, Young Jin Hong, Don Hee Ahn
Clin Exp Pediatr. 1995;38(5):633-640.   Published online May 15, 1995
Purpose : Childhood tuberculosis is often asymptomatic with low culture rate, but it may res-ult in serious complications via hematogenous spread. Therefore, this study was done to evalu-ate clinical features, laboratory findings in tuberculosis patients proved by culture. Methods : We reviewed retrospectively the medical records of 48 cases of proved tubercul-sosis at the department of Pediatrics, National Medical Center, during...
Case Report
A Case of Chronic Pancreatitis Complicated by Hemobilia
Sang Ook Nam, Jeong Kee Seo, Je Geun Chi, Kyung Mo Yeon
Clin Exp Pediatr. 1995;38(3):422-427.   Published online March 15, 1995
Hemobilia caused by pancreatic disease is very rare. The most common cause is a splenic artery pseudoaneurysm caused by acute and chronic inflammation of the pancreas. We experienced a case regarding as hemobilia as a complication of chronic relapsing pancreatitis in a 14 year-old boy. He was admitted with chief complaints of abdominal pain and hematemesis. Two years prior to admission,...
Original Article
Results of Chemotherapy of Hepatoblastoma and Hepatocellular Carcinoma in Children
Kyung Duk Park, Gi Woong Seong, Jae Kyung Lee, Hong Hoe Koo, Hee Young Shin, Hyo Seop Ahn
Clin Exp Pediatr. 1995;38(2):195-206.   Published online February 15, 1995
Purpose : Surgical excision has been the primary treatment for hepatoblastoma and hepatocellular carcinoma. However, at presentation, only one third of such tumors are surgically resectable. Without operation, the disease is fatal. Therefore, neoadjuvant chemotherapy has been introduced for conversion of the unresectable tumors into the resectable ones. We studied th e effects of chemotherapy for hepatic malignancy in children. Methods...
A Clinical Study on Childhood Leukemia
Joo Huh, Jong Bum Shin, Soon Yong Lee
Clin Exp Pediatr. 1994;37(5):655-665.   Published online May 15, 1994
Clinical analysis of 170 patients with childhood leukemia was made, who were admitted to the department o Pediatrics, Pusan Paik Hospital, Inje University, College of Medicine during 10 years from 1981 to 1990. The results were as follows: 1) The annual number of the patients with childhood leukemia was in the range of 6~25 cases. And the annual rate of the...
Case Report
A Case of Childhood Adenocarcinoma
Mi Jung Park, Moon Sung Psrk, Seunng Hwang Oh, Chuhl Joo Lyu, Ki Sup Chung, Byung Soo Kim
Clin Exp Pediatr. 1994;37(1):109-114.   Published online January 15, 1994
Gastric adenocarcinoma in childhood is an extremely rare disease with poor prognosis. We experienced a case in which a 14 year old female patient who was admitted with complaints of abdominal pain, indigestion and obstipation. Her physical examination revealed positive Blumer's rectal shelf, positive ascitic fluid cytology and typical radiologic and endoscopic findings suggesting gartric adenocarcinoma. She showed symptomatic improvement...
A Case of Solid and Papilary Tumor of Pancreas
Kyoung Bum Kim, Hae Won Cheon, Ji Hee Park, Kee Hyoung Lee, Kwang Chul Lee, Young Chang Tockgo
Clin Exp Pediatr. 1993;36(12):1765-1769.   Published online December 15, 1993
We report a cases of solid and papillary neoplasm of the pancreas, which is a rare pancreatic tumor. We described clinical characteristics, sonographic, computed tomographic and pathologic finding. The tumors had a smooth, enhanced capsule and variable internal architecture. The tumor was distributed tail of pancreas without local invasion. The origin of the tumor is probably from a multipotential stem...
Original Article
A Clinical Study of Childhood Soft Tissue Sarcoma
Hye Lim Jung, Hong Heo Koo, Hee Young Shin, Hyo Seop Ahn
Clin Exp Pediatr. 1993;36(9):1258-1270.   Published online September 15, 1993
Medicine, Seoul, Korea Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea To study the clinical characteristics and treatment results of childhood soft tissue sarcoma, the retrospective study was performed on 67 patients with soft tissue sarcoma, experienced at the Department of Pediatrics, Seoul National University Hospital from January, 1982 to July, 1990. The...
A Clinical Study of Testicular Relapse in Childhood Acute Lymphocytic Leukemia
Hye Ok Roh, Chuhl Joo Lyu, Seung Hwan Oh, Chang Hyun Yang, Kir Young Kim, Byung Soo Kim
Clin Exp Pediatr. 1993;36(5):680-686.   Published online May 15, 1993
From January 1984 to June 1991, we studied testicular relapsed patients among 105 cases of acute lymphocytic leukemia in children who were admitted to the Department of Pediatrics and Yonse Cancer Center, Yonsei University Severance Hospital. The results were as follows: 1) 15 out of 105(14.4%) cases of acute lymphocytic leukemia were diagnosed as testicular relapse. According to the prevalence by the...
A Study of Serum and Spinal Fluid Enzyme Such as CPK and LDH as Predictors of Neurologic Disability Following Perinatal Asphyxia
Min Hye Kim, Hye Jin Lee, Gyoung Hee Kim
Clin Exp Pediatr. 1993;36(5):664-670.   Published online May 15, 1993
Perinatal asphyxia is an insult to fetus or newborn due to lack of oxygen or perfusion to various organsm especially to brain, resulting in the important complication known as hypoxic inchemic encephalopathy. A clinical study was conducted on 30 newborns with perinatal asphyxia, who were admitted to Pediatric department of Ewha Women's University Hospital during 19 months period from Sep. 1990...
A Clinical Study of Myelodysplastic Syndrome in Children
Seong Hoon Hah, Hyo Seop Ahn
Clin Exp Pediatr. 1993;36(4):556-567.   Published online April 15, 1993
Myelodysplastic syndrome is a heterogeneous disease complex which is basically a clonal disorder and has characteristics of cytopenia of one or more cell series in peripheral blood and of dyspoiesis of precurosirs in bone marrow. Since the nature of this disease in childhooh is very different from that in adults, retrospective clinical study was performed with 17 confirmed patients who...
The Treatment Results of Childhood RhaMomyosarcoma
Chuhl-Joo Lyu, Byung Soo Kim, Eui Ho Hwang, Chang Ok Suh, Woo-Hee Cung
Clin Exp Pediatr. 1992;35(11):1520-1527.   Published online November 15, 1992
Rhabdomyosarcoma is a relatively common solid tumor in infants, children and adolescents, according for 4% to 8% of malignant disease in children less than 15 years old. Use of a multimodal approach to treatment has resulted in a dramatic improvement. Yonsei Cancer Center in Korea, since it's establishment in 1975, has been a state of multimodal approach. Thirty-seven cases of childhood...
Carcinomas in Childhood -A 10-Year Experience in Seoul National University Hospital-
Hong Hoe Koo, Kyung Duk Park, Hye Lim Jung, Sang Kyu Park, Hee Young Shin, Hyo Seop Ahn
Clin Exp Pediatr. 1992;35(10):1369-1376.   Published online October 15, 1992
Carcinomas in childhood differ from those in adults in their frequency, histologic type, and distribution of primary sites. In children, carcinomas are rare and few series have been published containing sufficient mumbers of cases to permit a reliable account of the incidence and survival of children with carcinoma. During a 10-year period, 1982-1991, we observed 40 patients less than 16...
A Clinical Study of Primay Gastrointestinal Lymphoma in Childhood
Hye Jung Joo, Chuhl-Joo Lyu, Byung Soo Kim, Euy Ho Hwang, Chang Ok Suh, Woo Ick Yang, Woo Hee Chung
Clin Exp Pediatr. 1992;35(9):1210-1219.   Published online September 15, 1992
The 18 cases of primary gastrointestinal lymphoma patients admitted to the Department of Pediatrics and Yonsei Cancer Center, College of Medicine, Yonsei University, during 15 years from January, 1975 to December, 1989 were reviewed on the bases of clinical characteristics, treatment, and survival rates. The results were summarized as follows; 1) The age of patients ranged from 3 years to 14 years,...
Statistical Study of Accidental Pediatric Patients in Emergency Room
Hyo Jeong Kim, Kwang Ik Song, Jin Bok Hwang, Chang Ho Han, Hye Li Chung, Young Dae Kwon
Clin Exp Pediatr. 1992;35(5):621-629.   Published online May 15, 1992
This study was designed to evaluate the prevalence and significant features of 3,234 pediatric accidental patients who visited emergency room during 6 years period from January 1982 to December 1987. 1) The accidental pediatric patients were 26.7% of total pediatric patients who visited emergency room The frequency of Childhood accidents was increased in later 2 years period(34.7%) compared with the early...
Case Report
A Case of Transient Erythroblastopenia of Childhood
Gi Hong Seo, Ae Young Kim, Kyeong Sook Cho, Jong Dae Cho
Clin Exp Pediatr. 1992;35(4):551-555.   Published online April 15, 1992
We have experienced a case of transient erythroblastopenia of childhood in a 7 years old male patient who was diagnosed by bone marrow aspiration. His hematologic improvement occurred spontaneously. A brief review of related literature was done.
Original Article
Incidence Estimation of Leukemia among Korean Children
Hong Hoe Koo, Hee Young Shin, Hyo Seop Ahn, Yoon-Ok Ahn
Clin Exp Pediatr. 1992;35(1):80-87.   Published online January 15, 1992
Leukemia is a neoplasm arising from the malignant transformation of hematopoietic cells. The incidence data of leukemia have not been available for Korean as a whole. The present study was therefore undertaken in order to estimate the incidence of childhood leukemia among Korean. The study population of this investigation was the beneficiaries of the Korea Medical Insurance Corporation(KMIC) during the period...
Re-evaluation of the indication for renal biopsy in childhood nephrotic syndrome.
Eun Kyoung Sohn, Byung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1991;34(6):805-811.   Published online June 30, 1991
Renal biopsy is indicated in nephrotic syndrome when histopathologic types other than minimal change pattern or the secondary nephrotic syndrome are suspected. But renal biopsy in children has some limitation because of the technical problem. In order to assess the clinicopathologic correlation and to re-evaluate the biopsy indication, the clinical manifestations and histopathologic types were analyzed statisically on the 86 cases of childhood nephrotic syndrome...
Malignant Schwannomas in children.
Joon Jai Kim, Dong Joo Shin, Dong Won Son, Hong Hoe Koo, In Sang Jeon, Hee Young Shin, Hyo Seop Ahn
Clin Exp Pediatr. 1991;34(4):525-531.   Published online April 30, 1991
Six pediatric patients who were diagnosed as malignant Schwannoma and treated at Seoul National University Children’s Hospital from Aug. 1981 to Jun. 1990 were reviewed. Mean age was 11 years and 1 month and all cases except one were over 10 years old. Of six cases, three (50%) were associated with von Recklinghausen’s disease. Overall male to female ratio was 1 : 2. In...
Endoscopic evaluation for gastrointestinal hemorrhage in childhood.
Cheol Ho Chang, Beom Soo Park, Jeong Kee Seo
Clin Exp Pediatr. 1991;34(4):515-524.   Published online April 30, 1991
The diagnosis and management of gastrointestinal tract hemorrhage in infants and children have been changed dramatically over the past decade. Although previous reviews of this subject have suggested that the cause of gastrointestinal tract bleeding may remain obscure in many patients, recent experience indicates that this is now uncommon. This advance is largely a result of the widespread and now routine application of fiberoptic...
A clinical observation on chylothorax in childhood.
Mi Jin Jung, Joon Jai Kim, Young Ah Lee, Chung Il Noh, Jung Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1991;34(4):497-506.   Published online April 30, 1991
Fourteen patients who had developed a chylothorax in childhood during a ten year period, from Jan. 1979 to July 1989, were reviewed by their hospital records. The chylothoraces occurred most frequently as complications of cardiothoracic surgeries in eight patients(57%). Four cases followed extrapericardial operations such as ligation of PDA and take-down of Blalock-Taussig shunt, and four cases followed intrapericardial operations such as corrective operations...
Molecular analysis of childhood acute lekemia.
Hack Ki Kim, Kyong Su Lee, Sung Hoon Cho, Du Bong Lee
Clin Exp Pediatr. 1991;34(2):164-171.   Published online February 28, 1991
Immunoglobulin (Ig) and T cell receptor 0 chain (TcR分) gene rearrangements can be used as ”genetic marker” of lineage and clonality in the study of lymphoproliferative disease. We analyzed genomic DNA of the bone marrow mononuclear cells from twenty six patients with acute leukemia in children. The patients were seventeen cases of acute lymphocytic leukmia (ALL), seven cases of acute nonlymphocytic leukemia (ANL) and...
A clinical study on goiter in childhood.
Yeong Hee Chung, Byung Min Moon, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1991;34(1):83-94.   Published online January 31, 1991
A clinical study was done on 96 cases of goiter in children which were diagnosed at pediatric department of Kwangju Christian Hospital during the period form January 1985 to December 1988. The observed clinical data were summarized as follows: 1) Preponderately femalels were affected with the sex ratio of 1:6.7. The majority of cases (78.2%) were around puberty. 2) On physical examination, 59 cases (85.5%) were found...
HLA Typing, Islet Cell Antibody and C-Peptide of Insulin Dependent Diabetes Mellitus in Children.
Hyeong Rae Cho, Sei Joong Ko, Duk Hi Kim, Hyun Chul Lee, Kap Bum Huh
Clin Exp Pediatr. 1990;33(12):1705-1712.   Published online December 31, 1990
35 childhood insulin-dependent (Typel) diabetes mellitus were typed for HLA and examined for presence of islet cell antibody and level of C-peptide. The following results were obtained: 1) HLA types were present as follows; HLA A24 (9) in 58%, DR3 in 38% and DR4 in 62%. This was slightly higher than the Korean population of 38%, 7% and 48% but there was no significant difference. 2) When...
Clinical Analysis on Childhood Accidents.
Won Seop Kim, Youn Jin Hong, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1990;33(12):1631-1638.   Published online December 31, 1990
We carried out a stastical & clinical analysis on 2,593 cases of childhood accidents visiting emergancy room of National Medical Center during last 5 years, from Jan. 1, 1984 to Dec. 31, 1988. The results were as follows: 1) The total percent of accidents among EMR visitors showed 6% increase in 1988 compared to that of in 1984 2) The most common type of accidents was trauma...
Clinical and Epidemiologic Studies on Childhood Asthma.
Youn Mo Ahn, Sun Ho Lee, Ha Baik Lee, Hahng Lee
Clin Exp Pediatr. 1990;33(5):632-641.   Published online May 31, 1990
The one-hundred-twenty-seven asthmatic children who were diagnosed and treated either through admission or through clinic visits at the Department of Pediatrics, Hanyang University Hospital from July 1987 to March 1989, were investigated for clinical patterns and epidemiologic correlations. The diagnosis of asthma was made by typical clinical history, physical findings and laboratory examina- tion. The results were as follows: 1) Sixty-three percent of the total population at...
Radiologic Evaluation About Urinary Tract Infection In Children.
Soon Wha Kim, Byung Rai Cho, Don Hee Ahn, Keun Chan Sohn, Chong Hyun Yoon
Clin Exp Pediatr. 1989;32(6):797-803.   Published online June 30, 1989
There had been total 165 cases of urinary tract infection who had been admitted to the ward of pediatrics, National Medical Center from ]an. 1986 to Sept. 1987. Among these, 80 cases had indication of radiologic evaluation; they were the first-documented urinary tract infection in male patients, the first documented urinary tract infection in female patients younger than 6 years of age,...
A Case of Trichobezoar.
Ue Chong Yang, Bong Sik Kong, Sang kyu Park, Ho Jin Park, Mi Ja Shin, Seok Hwan Shin
Clin Exp Pediatr. 1989;32(5):700-704.   Published online May 31, 1989
Trichobezoar is one of the rare diseases, which usually occurs in teen.aged girl who has an emotional disturbance and history of trichophagia. We experienced a case of gastric trichobezoar in a 8 year old girl, who had colicky abdominal pain and movable epigastric mass with the history of trichophagia. Diagnosis was suspected by the history of trichophagia and movable epigastric mass and confirmed by...
Infections in Childhood Leukemia.
Choong Won Lee, Young Sik Kim, Byung Kyu Park, Soon Ki Kim, Il Soo Ha, Hoan Jong Lee, Hyo Seop Ahn
Clin Exp Pediatr. 1989;32(5):659-664.   Published online May 31, 1989
A retrospective study was performed on twenty-nine children, who had experienced infection one or more times, among the thirty-eight children diagnosed as leukemia at the Department of Pediatrics, Seoul National University Hospital, between January, 1984 and June, 1985, and followed up for more than three years. The results were as follows; 1) The age of patients ranged from I year 5 months to 14 years...
An Epidemiological Study of Bronchial Asthma in Children Who Visited the Emergency Room.
Ju Kwan park, En Jung Kim, Bok Yang Pyun, Sang Jhoo Lee
Clin Exp Pediatr. 1989;32(2):215-222.   Published online February 28, 1989
Presently, an increasing incidence of Bronchial asthma in children is of concern to medical professionals. Worldwide data from surveys indicate a wide range for the prevalence of childhood asthma, it has been estimated that 5-10% of the young population. An epidemiological approach was used to test the prevalence of bronchial asthma out of all pediatric cases referred to the emergency room. 248 cases were selected...