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Clinical Lecture
The Effects of Postpartum Depression on the Development of Children
Esook Oh
Clin Exp Pediatr. 2005;48(5):469-475.   Published online May 15, 2005
Mother-infant interaction is a crucial component of an infant's cognitive, emotional and behavioral development. Most people are preoccupied with fetal education, the physical conditions of the postpartum mother and baby, and emphasizing an early start in the child's education. However, the effects of a mother's postnatal emotional state on the development of the infant are often overlooked. Postpartum depression is...
Case Report
A Case of Multiple Giant Coronary Aneurysms with Large Mural Thrombus due to Kawasaki Disease in a Young Infant
Eun Na Choi, Jeoung Tae Kim, Yuria Kim, Byung Won Yoo, Deok Young Choi, Jae Young Choi, Jun Hee Sul, Sung Kye Lee, Dong Soo Kim, Young Hwan Park
Clin Exp Pediatr. 2005;48(3):321-326.   Published online March 15, 2005
Kawasaki disease is an acute systemic vasculitis of unknown origin. Giant coronary aneurysm is one of the most serious complications, although peripheral artery vasculitis can produce life-threatening events. Myocardial ischemia and infarction can be caused by coronary artery stenosis, aneurysm, and stagnation of blood flow in coronary arteries which triggers thromboembolism. Atypical presentation in young infants often interferes with prompt...
Clinical Lecture
Benign Arrhythmias in Infants and Children
Jae Kon Ko
Clin Exp Pediatr. 2005;48(1):1-5.   Published online January 15, 2005
Pediatricians often encounter some electrocardiographic abnormalities in infants and children. However, treatment or referral to pediatric cardiologist is not indicated for all arrhythmias. Many of them are benign in nature. Benign arrhythmias can be defined as the arrhythmias that no serious problem currently exists and no treatment is needed. The prognosis of benign arrhythmias is so good that the condition...
Original Article
High Frequency Oscillatory Ventilation with Inhaled Nitric Oxide Combined Therapy in The Intractable Respiratory Failure Neonates
Mi Hyun Lee, Ji Eun Han, Sang Geel Lee
Clin Exp Pediatr. 2004;47(11):1167-1172.   Published online November 15, 2004
Purpose : Inhaled nitric oxide(iNO) has been known to improve oxgenation in newborns with persistent pulmonary hypertension(PPHN), but it's not clear that iNo treatment is effective in cases of acute, hypoxic respiratory failure and premature infants. In our study, high frequency oscillatory ventilation(HFV) with iNO combined therapy was tried in intractable respiratory failure neonates who showed no response to conventional...
A Clinical Study of Sepsis with Thrombocytopenia in Premature Infants
Jae Hoon Sim, So Ick Jang, Yun Jung Sim, Do Jun Cho, Dug Ha Kim, Ki Sik Min, Ki Yang Yoo
Clin Exp Pediatr. 2004;47(10):1058-1064.   Published online October 15, 2004
Purpose : This study was performed to characterize sepsis with thrombocytopenia in premature infants to determine if thrombocytopenia is a prognostic factor in sepsis in premature infants. Methods : We retrospectively analyzed the medical records of sepsis in premature infants admitted to the neonatal intensive care unit(N=41) at the Hallym University Sacred Heart Hospital from January 1999 to December 2002. The...
Case Report
A Case of Subdural Abscess Caused by Morganella morganii
Eun Young Park, Su Jin Lee, Phil Soo Oh, Kwang Nam Kim, Seung Myung Moon
Clin Exp Pediatr. 2004;47(9):1024-1027.   Published online September 15, 2004
Morganella morganii, a gram-negative bacillus and part of normal faecal flora, is recognised as a common cause of urinary tract infection. We report a rare case of subdural abscess caused by M. morganii in an infant. It was secondary to purulent meningitis. The patient improved with treatment that consisted of surgical excision and systemic antibiotics.
Original Article
A Comparison of Clinical Manifestations in Neonates and Infants Infected by Respiratory Syncytial Virus
In Suk Lim, Min Joo Shim, Byung Eui Kim, Ju Young Chung, Chang Keun Kim, Myoung Jae Chey, Sang Woo Kim, Soung Hee Kim, Tae Hee Han
Clin Exp Pediatr. 2004;47(9):949-952.   Published online September 15, 2004
Purpose : This study was performed to evaluate of clinical manifestations of neonatal respiratory syncytial virus(RSV) infection, and to evaluate of differences of clinical manifestations between the neonates and infants who were infected by RSV. Methods : We reviewed the medical record of 75 children who were younger than 12 months of age and infected by RSV. We classified then into...
Clinical Study of Benign Convulsion with Acute Gastroenteritis
Jin Hyung Cho, Kim Eun Joo, Sung Koo Kim, Seon Hee Shin, Kon Hee Lee, Hae Sun Yoon
Clin Exp Pediatr. 2004;47(8):855-860.   Published online August 15, 2004
Purpose : This study was performed to characterize clinical features of benign convulsions with acute gastroenteritis(CwG) in infants. Methods : We reviewed 83 consecutive seizures in 42 patients with CwG between January 1995 and December 2003. CwG was defined as convulsions having the following two characteristics : (a) seizures accompanied with symptoms of gastroenteritis without clinical signs of dehydration or electrolyte...
Measles Antibodies Measured by Plaque Reduction Neutralization Test in Infants during the First Year of Life
Sung Hee Oh, Hak Won Kim, Younghee Lim, Hahng Lee
Clin Exp Pediatr. 2004;47(8):827-832.   Published online August 15, 2004
Purpose : The 2000-2001 measles epidemic resulted in more than 50,000 cases with the highest attack rate occuring in infants less than one year of age, indicating the necessity of measles immunization before 12 months of age when a measles outbreak occurs again. The study was conducted to measure maternal measles antibody in infants by plaque reduction neutralization test(PRN), for...
Antithrombin III in the Diagnosis and Treatment of Disseminated Intravascular Coagulation in Premature Infants
Su Jin Cho, Hye Ryung Choi, Young Mi Hong, Kyung Hee Kim, Keun Lee, Eun Ae Park
Clin Exp Pediatr. 2004;47(7):740-745.   Published online July 15, 2004
Purpose : We evaluated the diagnostic implications and therapeutic efficacy of antithrombin III(AT III) in the disseminated intravascular coagulation(DIC) of premature infants. Methods : Ninety-two premature infants diagnosed with DIC and treated with AT III from March, 2000 to May, 2003 were retrospectively reviewed. Clinical manifestations, complete blood counts, coagulation tests, and AT III levels were compared between the two groups...
Clinical Outcomes of Infants with Failure to Gain Weight among Out-patients
Byoung Cheol Lee, Hae Rim Kim, Chan Lack Sohn, Sin Kam, Jin-Bok Hwang
Clin Exp Pediatr. 2004;47(6):604-610.   Published online June 15, 2004
Purpose : The three categories of failure to thrive are based on anthropometric measurements of weight, length, and head circumference for age. Type 1 is a failure to gain weight(FGW) due mainly to malnutrition. This study was performed to observe the clinical outcomes of infants with FGW, Type 1, among out-patients. Methods : Between October 2002 and July 2003, data from...
Survival Rate in Very Low Birth Weight Infants
Jae Ju Cho, Soon Bum Lee, Woo Sung Park, Young Pyo Chang
Clin Exp Pediatr. 2004;47(5):505-509.   Published online May 15, 2004
Purpose : We observed changes in the outcome of very low birth weight infants(VLBWI) admitted to the neonatal intensive care unit(NICU) of Dankook University Hospital(DKUH) in the last six years. Methods : The distribution of birth weight and gestational age, survival rate, neonatal complications, and causes of death for 228 VLBWI who had been admitted to DKUH from 1st January...
Decreased Nonlinear Coupling of Peripheral Blood Volume to Heart Rate in Preterm Infants
Eun-Young Park, Chang-Ryul Kim, Myung-Kul Yum
Clin Exp Pediatr. 2004;47(4):386-391.   Published online April 15, 2004
Purpose : We investigated the autonomic nervous and complex modulation of heart rate and peripheral blood volume, and linear and nonlinear coupling between heart rate and peripheral blood volume in full-term and preterm infants. Methods : In twenty healthy preterm infants and twenty full-term infants at postconceptional age of 30-37 and 38-41 weeks each, we recorded electrocardiogram and photoplethysmogram simultaneously during...
The Effect of Parenteral Nutrition and Respiratory Distress Syndrome in the Early Neonatal Period on Bone Mineralization at the Time of Reaching 2 kg Body Weight in Premature Infants
Yun-Jin Lee, Su-Eun Park, Jae-Hong Park
Clin Exp Pediatr. 2004;47(4):368-372.   Published online April 15, 2004
Purpose : To evaluate the effect of parenteral nutrition in early neonatal period on bone mineralization at the time of reaching 2 kg body weight in premature infants, bone mineral density(BMD) in infants who received long-term parenteral nutrition in the early neonatal period was measured and compared with infants who received enteral nutrition only. Methods : Twenty low birth weight infants(those...
Erratum
A Clinical Approach to Failure to Gain Weight in Infants
Jin-Bok Hwang
Clin Exp Pediatr. 2004;47(4):355-361.   Published online April 15, 2004
Failure to thrive is a term used to describe growth failure in infants and young children that may be accompanied by retarded social and motor achievements. The three categories of failure to thrive is based on anthropometric measurements of weight, length, and head circumference for age. Type 1 category, inadequate growth or loss of body weight with relatively normal height...
Case Report
Three Cases of Hypercalcemia Due to Vitamin D Intoxication in Infancy
Jin-Ho Choi, Mi-Sun Yum, Hyewon Hahn, Young Seo Park
Clin Exp Pediatr. 2004;47(3):332-337.   Published online March 15, 2004
Hypercalcemia in infancy is an uncommon disorder but has a potential of serious sequelae. Therefore, infants with hypercalcemia must be promptly investigated and need urgent management. We report three cases of infantile hypercalcemia caused by vitamin D intoxication, emphasizing diagnostic investigations and the course of treatment. The first and the second cases were thought to be vitamin D intoxication without...
Original Article
Risk Factors of Nephrocalcinosis in Very Low Birth Weight(VLBW) Infants
Gyu Hong Shim, Jin A Lee, Yun Jung Shin, Ee Kyung Kim, June Dong Park, Beyong Il Kim, Jung Hwan Choi
Clin Exp Pediatr. 2004;47(3):275-281.   Published online March 15, 2004
Purpose : Nephrocalcinosis in very low birth weight(VLBW) infants were known to be caused by a longer duration of furosemide use. However, etiologies, pathogenesis and risk factors remain unclear. Therefore, we examined the incidence and risk factors of nephrocalcinosis in VLBW infants retrospectively. Methods : Inborn babies of birth weights less than 1,500 gm were examined retrospectively. Data were reviewed on...
The Effect of Post-natal Weight Changes on the Development of Bronchopulmonary Dysplasia in Infants with Respiratory Distress Syndrome
Hye One Jhon, Young Min Kim, Hee Joo Hong, Chong Woo Bae
Clin Exp Pediatr. 2004;47(3):269-274.   Published online March 15, 2004
Purpose : The subjects were compared and measured for differences in the aspects of weight changes between the groups that developed bronchopulmonary dysplasia(BPD) after treatment and those that did not, to analyze the relations between the patterns of early weight change after birth and the development of BPD. Methods : Retrospective analysis of medical records were performed for birth weight and...
The Effect of Histologic Chorioamnionitis on the Development of Respiratory Distress Syndrome and Chronic Lung Disease in Preterm Infants
Heui seung Jo, Beyong Il Kim, Chang Won Choi, Jun Dong Park, Chong Jai Kim, Jung-Hwan Choi
Clin Exp Pediatr. 2004;47(2):150-156.   Published online February 15, 2004

Purpose: Histologic chorioamnionitis may play a role in the development of respiratory distress syndrome(RDS) and chronic lung disease(CLD) independently or through its association with preterm birth. We investigated the relationship between histologic chorioamnionitis and clinical complications including, RDS and CLD, of preterm infants. Methods: Clinical data were collected retrospectively from 478 preterm infants(gestational period≤34 weeks) who were admitted to the neonatal...
Ultrasonographic Bladder Parameters for Successful Suprapubic Bladder Aspiration
Sung Chul Baek, Hoe Kyoung Koo, Cheol Hong Kim, Kyung Bum Kim, Hyun Hee Lee, Byung Min Choi, Kee Hwan Yoo, Young Suk Hong, Dong Gwan Han
Clin Exp Pediatr. 2004;47(2):187-192.   Published online February 15, 2004
Purpose : Suprapubic bladder aspiration(SBA) is a widely accepted method of obtaining sterile urine for culture in neonates but has a relatively low success rate and a few serious complications during SBA procedure. To improve the chance of obtaining urine, we determined the ultrasonographic bladder parameters(diameters and volume) to confirm that the bladder is adequately distended for successful aspiration of...
Change in the Limit of Viability of Fetal Infants
Chang Won Choi, Jong Hee Hwang, Jae Won Shim, Sung Sin Kim, Sun Young Ko, Eun Kyung Lee, Yun Sil Chang, Won Soon Park
Clin Exp Pediatr. 2003;46(12):1194-1199.   Published online December 15, 2003
Purpose : To determine the change in the limit of viability in fetal infants and the incidence of major complications in neonatal intensive care unit(NICU) at Samsung Medical Center(SMC). Methods : Sevety-three infants weighing less than 800 g at birth and 117 infants born earlier than 27 weeks gestational age, who were admitted to NICU at SMC between November 1994...
Case Report
A Case of Rickets Developed after Feeding on Sunsik for Seven Months
Jeong-A Yang, Kyung-A Jang, Hye-Won Park, Wook Jang, Man-Yong Han, Young-A Cho, Eun Lee
Clin Exp Pediatr. 2003;46(11):1143-1146.   Published online November 15, 2003
Rickets is a nutritional disorder which is caused either by deficiency of vitamin D or by a defective activation of vitamin D. In these days, even though the incidence of rickets has decreased through adequate nutritional support, we sometimes experience rickets in babies receiving a prolonged special diet as therapy for chronic diarrhea, or those subject to a in receiving...
Original Article
Comparison of Clinical Courses According to the Existence of Patent Ductus Arteriosus in Respiratory Distress Syndrome
Ju Hee Seong, Hyeon Joo Lee, Hyun Kee Hong, Chong-Woo Bae, Yong-Mook Choi
Clin Exp Pediatr. 2003;46(11):1080-1084.   Published online November 15, 2003
Purpose : To compare perinatal characteristics, clinical courses, and overall morbidity between respiratory distress syndrome(RDS) with patent ductus arteriosus(PDA) and RDS without PDA in neonates. Methods : Eighty-three neonates who were diagnosed and treated for RDS in the neonatal intensive care unit(NICU) from Jan. 2000 to Dec. 2002 were included in this study. RDS was complicated with PDA(group A) in...
A Study on the Changes in Ventilator Care Rate and Outcome of Very Low Birth Weight Infants During Last Four Years
Byun Kyung Jung, Yeoung Ju Kim, Sang Geel Lee
Clin Exp Pediatr. 2003;46(11):1073-1079.   Published online November 15, 2003
Purpose : Recently there has been a decrease in ventilator care rate and duration of very low birth weight infants(VLBWI) in Fatima Hospital. The aims of this study were to survey the frequency and duration of ventilation in VLBWI and to develop a non-invasive neonatal intensive care unit (NICU) policy. Methods : We performed a retrospective study of 284 newborn of...
Changes of Neutrophil Count in Peripheral Blood of the Neonate with Periventricular Leukomalacia
Hwan Seok Lee, Kyung Pil Park, Heng Mi Kim
Clin Exp Pediatr. 2003;46(10):966-971.   Published online October 15, 2003
Purpose : It is now well established that infection and inflammation play an important role in the pathogenesis of ischemic brain damage. The loss of neutrophils from systemic circulation is an associated finding in injury mediated by granulocyte. Periventricular leukomalacia(PVL) caused by ischemia is the principal form of brain injury in premature infants. This study was conducted to evaluate whether...
Case Report
A Case of Recurrent Herpes Simplex Virus Disease of a Preterm Infant, Who Needed Continuous Oral Acyclovir Suppressive Therapy
Sung Seok Kim, Ki Woong Hong, Eun Ryoung Kim, Young-Don Kim, Kyoo Man Lee
Clin Exp Pediatr. 2003;46(9):939-949.   Published online September 15, 2003
Neonatal herpes simplex virus(HSV) infections result in significant morbidity and mortality. Although acyclovir treatment has improved survival, severe neurological sequelae can occur in the majority of survivors. HSV infections limited to the skin, eyes and mouth(SEM) can cause neurologic impairment. A direct correlation exists between the development of neurologic deficits and the frequency of cutaneous HSV recurrences. National Institutes of...
Original Article
Changes in Incidence, Survival Rate and Morbidity of Very Low Birth Weight Infants
Young Ok Kim, Sun Hui Kim, Chang Yee Cho, Young Youn Choi, Jin Hwa Kook, Tae Ju Hwang
Clin Exp Pediatr. 2003;46(8):769-776.   Published online August 15, 2003
Purpose : The survival rate of very low birth weight infants(VLBWI) has improved by virtue of specialized neonatal care. This study was performed to analyze the changes in incidence, survival rate and morbidity of VLBWI who admitted to Chonnam National University Hospital from 1996 to 2001. Methods : We enrolled 565 VLBWI, and compared the incidence and the survival rate according...
Case Report
A Case of Scrotal Abscess Associated with Gastroenteritis and Sepsis due to Salmonella Group D in a One Month Old Infant
You Sun Choi, Yoon Suk Jung, Sun Il Kim, Sung Hee Oh
Clin Exp Pediatr. 2003;46(6):602-605.   Published online June 15, 2003
Acute gastroenteritis due to Salmonella species, which usually improves on conservative treatment, can progress to sepsis and extraintestinal focal infection in very young infants. Frequent sites for extraintestinal infections are meninges, bone, joints, spleen and intravascular sites but scrotal abscess due to salmonella in children has been very rare. Literature search revealed only one newborn case of scrotal abscess with...
Original Article
Clinical Characteristics of Kawasaki Disease in Infants Younger than 3 Months of Age
Soo Jeong Lee, So Jung Kim, Hae Soon Kim, Sejung Sohn
Clin Exp Pediatr. 2003;46(6):591-596.   Published online June 15, 2003
Purpose : Kawasaki disease(KD) is rare in infants <3 months of age. In this younger group, the diagnosis may be delayed due to lack of most of the clinical criteria, resulting in a high risk of cardiac complications. We examined clinical characteristics in these patients for early recognition and treatment. Methods : We conducted a retrospective study on the infants...
Complications and Perinatal Factors According to the Birth Weight Groups in the Infants of Diabetic Mothers
Kyung-Ran Son, Hee-Jo Back, Chang-Yee Cho, Young-Youn Choi, Tae-Bok Song, Chun-Hak Park
Clin Exp Pediatr. 2003;46(5):447-453.   Published online May 15, 2003
Purpose : This study was performed to compare complications and perinatal factors according to the birth weight groups in the infants of diabetic mothers(IDM). Methods : Three hundred and one singleton diabetic mothers and their babies of more than 30 weeks' gestational age admitted in the department of Pediatrics, Chonnam University Hospital from January 1996 to March 2002 were enrolled....
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