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Original Article
Effects of Growth Hormone Therapy in Children with Idiopathic Short Stature
Kyong A Lee, Heon Seok Han
Clin Exp Pediatr. 2005;48(8):865-870.   Published online August 15, 2005
Purpose : The use of growth hormone(GH) to promote growth in normal short children without classical GH deficiency is controversial. Numerous foreign studies have shown the effects of GH therapy in children with idiopathic short stature(ISS) whereas few has been interested in Korea. Therefore, this study is designed to investigate the effects of GH therapy on ISS by observing correlations...
Case Report
A Case of Tuberous Sclerosis with Hydrocephalus and Multiple Cardiac Tumors in Neonatal Period
Young Jun Song, Won Seop Kim, Beom Soo Park, Heon Seok Han
Clin Exp Pediatr. 2000;43(2):294-299.   Published online February 15, 2000
Several different tumors in different tissues(including the central nervous system, heart, kidney, liver, bone, and soft tissues) are found to be associated with tuberous sclerosis. In the brain, this tumor characteristically arises from the floor of the lateral ventricle and often occluded the foramen of Monro. Cardiac tumor is among the earliest signs of tuberous sclerosis and occurs in over...
A Case of Spontaneously Remitted Congenital Minimal Change Nephrotic Syndrome
Tae Sun Ha, Kyung Hee Lee, Beom Soo Park, Heon Seok Han
Clin Exp Pediatr. 1995;38(9):1288-1292.   Published online September 15, 1995
Nephrotic syndrome is a condition with severe proteinuria, hypoalbuminemia, and edema. When the syndrome develops within the first 3 months of life, it is generally considered as congenital and the overall outcome in this group seems to be worse than in miniaml change lesion that occurs at an older age regardless of the pathologic findings. A female infant with congenital nephrotic...
Three Cases of Necrotizing Lymphadenitis in Childhood
Seong Hoon Hah, Dong Woon Shin, Kyung Hee Lee, Tae Sun Ha, Beom Soo Park, Heon Seok Han, Sang-Hoon Cha, Geon Kook Lee
Accepted January 1, 1970  
Necrotizing lymphadenitis(named as "Kikuchi disease"), initially described by a Japanese pathologist as "a histiocytic necrotizing lymphadenitis with paracortical necrosis, plasmacytoid monocytes infiltration and prominent phagocytic appearance" has been found worldwide. Be-cause of its self-limited course, it has been well known that what should be considered as more important issues are its deatiled pathologic criteria for confirmation and thorough concern about...
Original Article
Growth Promoting Effect of Recombinant methionyl-Growth Hormone in Children with Chronic Renal Failure
Heon Seok Han, Yong Choi, Hyung Ro Moon
Clin Exp Pediatr. 1992;35(10):1355-1360.   Published online October 15, 1992
The authors studied the growth-promoting effect of yeast-derived methionyl-hGH in short statured children with uremic chronic renal failure. The subjects were prepubertal chronic renal insufficient patients whose height standard deviation scores were below -2.0. Two boys and two girls participated in this study. Chronic renal insufficiency was the only cause for the short stature. HGH was given to the subjects in dose...
Standard of Ear Size in Korean Children
Heon Seok Han, Hyung Ro Moon
Clin Exp Pediatr. 1992;35(8):1089-1095.   Published online August 15, 1992
Measurement of 1298 Korean Children in Seoul (male 661; female 637) resulted in normal standard data for ear length and width by their age and sex. 1) Ear length and width were as follows respectively : 36.0¡¾2.5mm 21.5¡¾2.5mm in male neonate, 56.3¡¾3.1mm 30.6¡¾3.2mm at 6yr boy, 63.2¡¾3.5mm 33.4¡¾3.2mm in 14 yr adolescent male, 35.5¡¾2.0mm 21.2¡¾2.1mm in female neonate, 54.6¡¾3.1mm 28.7¡¾2.4mm in...
Clinical study on lipoid pneumonia caused by aspiration of squalene.
Dong Joo Shin, Beom Soo Park, Moon Sun Yang, Heon Seok Han, Young Yull Koh, Hyung Ro Moon, Chang Yeon Lee
Clin Exp Pediatr. 1991;34(5):654-661.   Published online May 31, 1991
A clinical observation was made on 14 cases of lipoid pneumonia, who visited department of pediatrics, Seoul National University Children’s Hospital from August, 1988 to June, 1990. The results were as follows; The ratio of male to female was 10 : 4. Age at diagnosis was 1.1±1. 3 years, and ranged from 3 months to 4.9 years. The age at taking Squalene ranged...
The etiologies and the clinical manifestations of hypoglycemia in infancy and childhood.
Nam Seon Beck, Dong Joo Shin, Heon Seok Han, Sei Won Yang, Hyung Ro Moon
Clin Exp Pediatr. 1991;34(4):480-486.   Published online April 30, 1991
To analysis age at onset, clinical manifestations, etiologies, complication and management of hypoglycemia, the authors reviewed seventeen cases of hypoglycemia who were admitted to Seoul National University Children’s Hospital because of hypoglycemic symtoms from March, 1982 to February, 1990. In neonate group, which included five patients, their initial symtoms were apnea, cyanosis, sweating and hand rigidity, with the causes of two hyperinsulinemic hypoglycemias, one...
A case of hypomelanosis of Ito accompanying ureteral duplication and hypomelanotic scalp hair.
Dong Woo Son, Beom Soo Park, Heon Seok Han, Hae Il Jung, Yong Choi, Hyung Ro Moon, Seon Hoon Kim, Hwang Choi
Clin Exp Pediatr. 1991;34(2):281-286.   Published online February 28, 1991
Hypomelanosis of Ito (incontinentia pigmenti achromians) is a cutaneous abnormality consisting of bizarre, whorly, linear, or patchy hypopigmentation over variable portion of body surface. Multiple assocaited defects in other systems occur in three quarters of the affected individuals. Most common- ly, the central nervous system, eye, and musculoskeletal structures are involved. It is suggested that the cutaneous abnormality, which is often detectable at birth...
Clinical Observation on isolated TRH deficient Congenital Hypothyroidism.
Heon Seok Han, Hyung Ro Moon
Clin Exp Pediatr. 1990;33(10):1388-1393.   Published online October 31, 1990
Clinical features and endocrine function of 3 children with isolated TRH deficient congenital hypothyroidism followed at Seoul National University Children’s Hospital from Aug, 1986 to Aug. 1990 were reviewed. During above period 262 congenital hypothyroid patients were followed at endocrine clinic, number of congenital primary hypothyroidism was 218 cases (83.2%), and that of congenital secondary hypothyroidism was 44 cases (16.8%). Of the congenital primary hypothyroidism,...
Whole Cow's milk Related iron Deficiency Anemia in Early Childhood.
In Sang Jeon, Heon Seok Han, Hyo Seop Ahn, Jin Q Kim
Clin Exp Pediatr. 1990;33(10):1374-1379.   Published online October 31, 1990
To study the relationship between large amount of whole cow’s milk (WCM) intake and iron deficiency anemia (IDA) in early childhood, we carried out the study on 9 children with IDA, who were fed WCM, about 1,000 ml over 3 months, experienced at the department of Pediatrics, Seoul National University Hospital, during 5 months from March 1989 to July 1989. The results were as...
Case Report
Two Case of Infantile Cortical Hyperostosis.
Hae Lim Chung, Heon Seok Han, Young Yull Koh, Yong Seung Hwang, kyung Mo Yeon
Clin Exp Pediatr. 1986;29(4):441-445.   Published online April 30, 1986
We experienced 2 cases of Infantile Cortical Hyperostosis. Case I was 2V2 month old male who complained of irritability and tender swelling on extremities. Case I was 3 month old male who complained of deformities in both legs and irritability on handling above lesions. The diagnosis was established by typical clinical findings and radiological evidence A brief review of...
Two Case of Watson-Alagille Syndrome.
Heon Seok Han, Soo Heum Lim, Young Sun Kim, Jeong Kee Seo, Hyung Ro Moon
Clin Exp Pediatr. 1985;28(10):1047-1051.   Published online October 31, 1985
Watson-Alagille syndrome (Arteriohepatic dysplasia, Syndromatic paucity of interlobular bile duct), a disease characterized by chronic liver disease, characteristic facies, cardiova scular abnormalities, and vertebral arch abnormalities has paucity of interlobular bile ducts on histologic examination of liver. We experienced two cases of Watson-Alagille syndrome in a 7-month-old male infant and a 12-month-old male infant who had the chief complaint of...
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