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Case Report
A family with Townes-Brocks syndrome with congenital hypothyroidism and a novel mutation of the SALL1 gene
Won Ik Choi, Ji Hye Kim, Han Wook Yoo, Sung Hee Oh
Clin Exp Pediatr. 2010;53(12):1018-1021.   Published online December 31, 2010

Townes-Brocks syndrome (TBS) is a rare autosomal dominant congenital disorder caused by mutations in the SALL1 gene. Its signs and symptoms overlap with other genetic syndromes, including VACTERL association, Pendred syndrome, Baller-Gerold syndrome, and cat eye syndrome. Structural vertebral abnormalities, hypoplasia of the thumb, and radial bone abnormalities, which are not usually associated with TBS, help in the differential diagnosis...

Postnatal cytomegalovirus infection in an extremely premature infant transmitted via breast milk: A case report
Ji Hye Kim, Eun-Jin Chung, Hyun Kyung Park, Soo Ji Moon, Su-Mi Choi, Sung Hee Oh
Clin Exp Pediatr. 2009;52(9):1053-1058.   Published online September 15, 2009
Cytomegalovirus (CMV) is one of the most commonly encountered viral pathogens in newborn infants and is found in 0.3-2.4% of all live births. It has been demonstrated that 40-96% of seropositive mothers shed the virus via their breast milk. Breast milk containing CMV can cause almost one-third of CMV infections occurring in infants. A case of postnatal CMV infection in...
Two adolescent cases of Fitz-Hugh-Curtis syndrome
Ji Hye Kim, Sung Hee Oh
Clin Exp Pediatr. 2009;52(9):1038-1043.   Published online September 15, 2009
Two adolescent cases of Fitz-Hugh-Curtis syndrome, which has not been previously reported in Korean girls, presenting with right upper-quadrant abdominal pain, nausea, vomiting, and fever are reported here. A careful and thorough inquiry into the sexual history of the first patient, which was not done upon admission, led to a careful reassessment of the dynamic abdominal computed tomography scan revealing...
Erratum
Provisional update on varicella vaccination in Korea, 2008
Eun Hwa Choi, Kyung Hyo Kim, Jong-Hyun Kim, Su Eun Park, Seon Hee Shin, Sung Hee Oh, Hoan Jong Lee, Dae Sun Jo, Jae Kyun Hur, Young Jin Hong
Clin Exp Pediatr. 2008;51(6):665-667.   Published online June 15, 2008
Human Papillomavirus Vaccine
Kyung Hyo Kim, Jong-Hyun Kim, Su Eun Park, Seon Hee Shin, Sung Hee Oh, Hoan Jong Lee, Dae Sun Jo, Eun Hwa Choi, Jae Kyun Hur, Young Jin Hong
Clin Exp Pediatr. 2007;50(8):811-819.   Published online August 15, 2007
Rotavirus Vaccine
Su Eun Park, Kyung Hyo Kim, Jong-Hyun Kim, Seon Hee Shin, Sung Hee Oh, Hoan Jong Lee, Dae Sun Jo, Eun Hwa Choi, Jae Kyun Hur, Young Jin Hong
Clin Exp Pediatr. 2007;50(8):803-810.   Published online August 15, 2007
Review Article
Update in varicella vaccination
Sung Hee Oh
Clin Exp Pediatr. 2006;49(3):229-234.   Published online March 15, 2006
Varicella, which is mostly a benign disease, but also can cause considerable health burden in the community, can be prevented by immunization with live attenuated varicella vaccine. Higher uptake of varicella vaccine by universal immunization in North America has apparently been associated with decline in the number of reported cases of varicella, varicella-related hospitalizations, and the number of deaths caused...
Original Article
Lymphadenitis following intradermal BCG vaccination
Hey Sung Baek, Ji Young Chang, Su Ji Moon, Sung Hee Oh
Clin Exp Pediatr. 2006;49(1):46-50.   Published online January 15, 2006
Purpose : Intradermal BCG vaccine has not well been accepted by pediatric practitioners due to BCG lymphadenitis. Therefore, this study was undertaken to find out the incidence of lymphadenitis following intradermal BCG vaccination and its clinical outcome. Methods : One thousand and fifty infants, who received intradermal BCG(French 1173 P2, Korea Tuberculosis Association) vaccination in the Well Baby Clinic of Hanyang...
Causative Organisms of Urinary Tract Infection in Children, and their Antibiotic Susceptibility
Yoon Duk Kang, Nam Su Kim, Sung Hee Oh
Clin Exp Pediatr. 2004;47(10):1065-1071.   Published online October 15, 2004
Purpose : In caring patients with urinary tract infection(UTI), it is prominent to know causative agents and their antimicrobial susceptibilities, of which domestic data appear somewhat different from those reported in the literature. The study was done to learn the distribution of pathogens causing UTI and their antimicrobial susceptibilities in Korean children. Methods : One hundred forty two inpatients diagnosed...
Measles Antibodies Measured by Plaque Reduction Neutralization Test in Infants during the First Year of Life
Sung Hee Oh, Hak Won Kim, Younghee Lim, Hahng Lee
Clin Exp Pediatr. 2004;47(8):827-832.   Published online August 15, 2004
Purpose : The 2000-2001 measles epidemic resulted in more than 50,000 cases with the highest attack rate occuring in infants less than one year of age, indicating the necessity of measles immunization before 12 months of age when a measles outbreak occurs again. The study was conducted to measure maternal measles antibody in infants by plaque reduction neutralization test(PRN), for...
Case Report
Two Pediatric Patients with Neutropenia and Thrombocytopenia Associated with Parvovirus B19 Infection
Dong Koo Kim, Young Dai Kim, Ho Jun Lim, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 2004;47(3):338-342.   Published online March 15, 2004
Parvovirus B19, a member of the Erythrovirus genus, is the only member of the Parvoviridae family known to be pathogenic in humans. Haematological consequences of B19 infection arise due to a direct cytotoxic effect on erythroid progenitors in bone marrow, resulting in interruption of erythrocyte production. The physiology of host haematopoiesis and competence of the immune response each determines clinical...
A Case of Scrotal Abscess Associated with Gastroenteritis and Sepsis due to Salmonella Group D in a One Month Old Infant
You Sun Choi, Yoon Suk Jung, Sun Il Kim, Sung Hee Oh
Clin Exp Pediatr. 2003;46(6):602-605.   Published online June 15, 2003
Acute gastroenteritis due to Salmonella species, which usually improves on conservative treatment, can progress to sepsis and extraintestinal focal infection in very young infants. Frequent sites for extraintestinal infections are meninges, bone, joints, spleen and intravascular sites but scrotal abscess due to salmonella in children has been very rare. Literature search revealed only one newborn case of scrotal abscess with...
A Case of Vascular Ring Associated with Tracheitis Due to Type b Haemophilus influenzae
Su Hyun Kim, Yoon Sook Chung, Sung Hee Oh, Nam Su Kim, Hyuck Kim
Clin Exp Pediatr. 2002;45(2):261-266.   Published online February 15, 2002
Vascular ring, originating from abnormal regression of the aortic arch during fetal life, can cause prolonged and recurrent respiratory symptoms and dysphagia when the diagnosis is delayed. We report a 4 month old girl with vascular ring, who had been treated for persistent respiratory symptoms including stridor, wheezing, and dyspnea soon after birth. Initially her respiratory symptoms were thought to...
Erratum
Distribution of Anti-Mumps IgM Antibody in Children Presumptively Diagnosed of Mumps
Sung Hee Oh, Do Hack Yum, Jin Han Kang, Young Mo Sohn, Hoan Jong Lee, Bok Yang Pyun, Young Jin Hong, Chang Hwi Kim
Clin Exp Pediatr. 2001;44(1):17-25.   Published online January 15, 2001
Purpose : Outbreaks of mumps continue to occur, even though the number of patients diagnosed of mumps has decreased considerably with the widespread use of vaccine. The accurate diagnosis of mumps is needed to understand the epidemiology of mumps and analyse the safety and effectiveness of vaccine. Therefore, we attempted to appraise the accuracy of provisional diagnosis of mumps in...
Original Article
Tuberculin Reactivity to 2 TU of PPD RT23 Following Intradermal BCG Vaccination in Neonates
Jong Hwa Lee, Sung Hee Oh
Clin Exp Pediatr. 2000;43(11):1418-1422.   Published online November 15, 2000
Purpose : 2 TU of PPD RT23 has been substituted for 5 TU of PPD RT23 since 1998 in Korea without adequate evaluation. This study was undertaken to evaluate the tuberculin reactivity to 2 TU of PPD RT23 following intradermal BCG vaccination in neonates. The results were compared with the previous report generated with 5 TU of PPD RT23 in...
Antibody Response and Adverse Reaction Following Immunization with MMR Vaccine Produced on Human Diploid Cells in Korean Children
Sung Hee Oh, Jin Han Kang, Young Mo Sohn, Hoan Jong Lee, Bok Yang Pyun, Chang Hwi Kim
Clin Exp Pediatr. 2000;43(4):489-495.   Published online April 15, 2000
Purpose : This prospective study was performed to evaluate the immunogenecity and safety of MMR vaccine(Triviraten Berna￠c) in Korea children. Methods : Seventy-three infants aged between 12 to 18 months were recruited from several university hospitals between December 1995 to June 1996. MMR vaccine(Triviraten Berna￠c) was administrered and blood was obtained before and 6-10 weeks after vaccination. IgG antibodies against measles,...
Clinical Lecture
Careful Choice of Antimicrobial Agents in Primary Pediatric Care
Sung Hee Oh
Clin Exp Pediatr. 2000;43(4):455-462.   Published online April 15, 2000
Original Article
The Effect of Measles Vaccination Before Turning 1 Year-old on the Measles Antibody Response to Immunization with MMR
Soo Jung Choi, Young Jae Koh, Young Mo Soh, Hoan Jong Lee, Sung Hee Oh
Clin Exp Pediatr. 1998;41(7):909-916.   Published online July 15, 1998
Purpose : With the implementation of measles vaccination programs, the number of patients with measles has decreased. However, epidemics still occur with high morbidity in infants less than 1 year of age. This fact calls for the establishment of optimal preventive measures against measles. The study was carried out to determine the effect of measles vaccination on an infant immunized...
Case Report
A Fatal Case of Systemic Juvenile Rheumatoid Arthritis with Disseminated Intravascular Coagulation
Eun Young Park, Sung Hee Oh
Clin Exp Pediatr. 1998;41(1):129-134.   Published online January 15, 1998
Disseminated intravascular coagulation(DIC) occurs rarely but can cause death in patients with juvenile rheumatoid arthritis(JRA), especially in the systemic type. The reports of DIC complicating JRA have increased recently. We experienced a 13 - year - old female patient with systemic JRA who died of DIC. The patient had been managed with aspirin, steroid, nonsteroidal anti-inflammatory drug for 7 years,...
Original Article
The Retrospective Study on Antibiotics Treatment in Acute Gastroenteritis
Ji Hye Kim, Sung Hee Oh
Clin Exp Pediatr. 1997;40(6):826-834.   Published online June 15, 1997
Purpose : Most of the gastroenteritis due to viruses and some bacteria can be successfully managed by oral and/or intravenous fluid-electrolyte replacement and antibiotic therapy is unnecessary and even harmful. It is, however, not uncommon practice to prescribe antibiotics when acute gastroentritis is suspected. Therefore authors analysed the clinical courses of the patients treated for acute non-bacterial gastroenteritis in a university hospital to assess...
Epidemiology of Varicella in Korea Based on Pediatrician's Office Practice
Dong Jun Kim, Hyeon Soo Park, Sang Yun Lee, Kee Surk Park, Taik Kill Kim, Young Hoon Song, Jin Choi, Jin Woo Han, Young Suk Song, Tae Jin Park, Hong Kun Kim, Soo Yup Lee, Sun Ho Lee, Hak Won Kim, Sung Hee Oh
Clin Exp Pediatr. 1997;40(5):620-628.   Published online May 15, 1997
Purpose : Although varicella outbreakes have frequently occured, the epidemiology of varicella in Korea has not well been delineated. Furthermore without enough investigation with regard to safety and efficacy of varicella vaccine in Korean population, thevaccine has begun to be used in healthy children. Therefore the authors analized the clinical features of patients diagnosed of varicella to aid in understanding...
Report of Nationwide Epidemiology of Aseptic Meningitis Outbreak in 1993 in Korea
Sung Hee Oh, Moo-Song Lee, Jin Han Kang, Chang Hwi Kim, Chong Young Park, Young Mo Sohn, Hoan Jong Lee, Chung Sik Chun, Sang Mann Shin
Clin Exp Pediatr. 1996;39(1):42-52.   Published online January 15, 1996
Purpose : There has been no nationwide report pertaining to the epidemiology of aseptic meningitis, although a great numer of patients have been diagnosed of the illness. Therefore, we report an explosive outbreak of aseptic meningitis occured in a nationwide scale in 1993. Methods : Aseptic meningitis epidemiology surveillence was performed retrospectively on the patients diagnosed of aseptic meinigitis from January...
Case Report
Toxic Shock Syndrome in a 13 Year Old Boy
Ji Hye Kim, Sung Hee Oh
Clin Exp Pediatr. 1995;38(12):1706-1712.   Published online December 15, 1995
Toxic Shock Syndrome(TSS), known to be mediated by toxins produced by Staphy¡ⓒlococcus aureus, is a potentially fatal multisystemic illness unless treated properly. Although the reported cases of TSS were primarily among menstruating women, more cases of TSS among children, nonmenstruating women and male adults have been reported recently. In Korea, however, TSS has not drawn much attention yet, and no...
Original Article
Trend of Maternal Measles Antibody in Korean Infants before 10 Months of Age
Phil-Soo Oh, Sung Hee Oh
Clin Exp Pediatr. 1995;38(5):619-624.   Published online May 15, 1995
Purpose : The measles epidemic occurrence has not well been controlled in Korea. Vaccin- ation schedule for measles in Korea has been modified in several occasions with insufficient da ta base. The most recent recommendation is to immunize at 9 months of age with measles va-ccine(at 6 months of age during epidemics) and reimmunize at 15 months of age with...
A Study on Clinical Characteristics of Maxillary Sinusitis in Korean Children
Dong Nam Kim, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 1995;38(3):319-327.   Published online March 15, 1995
Purpose : Paranasal sinusitis, easily overlooked owing to it's benign symptomatology, should be considered when the upper respiratory tract infction persists longer than seven days. Without early recognition and appropriate management, the disease will take a chronic course and the incidence of complications will be increased. The significance of paranasal sinusitis among Korean children has not appropriately been appreciated; therefore,...
Comparison of Tuberculin Skin Test Results and Adberse Reactions Following BCG Vaccination In Various Infant Groups of Different Ages
In Seung Park, Dong Ki Han, Ho Joon Lim, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 1993;36(9):1300-1307.   Published online September 15, 1993
Most authorities including WHO recommended immununizing infants with BCG as early as possible in areas prevalent with tuberculosis, however the optimal time for immunization has not well been characterized. Therefore the investigation was undertaken by vaccinating various infant groups of different ages with BCG and subsequently evaluating for adverse effects and tuberculin reactions, in order to contribute to undestanding the...
Case Report
A Case of Chronic Granulomatous Disease
So Young Lee, Dae Chul Kim, Sung Hee Oh, Hahng Lee, Hyang Eun Sohn, Wha Soon Chung, Young Hyeh Ko, Moon Hyang Park
Clin Exp Pediatr. 1992;35(5):704-712.   Published online May 15, 1992
Chronic granulomatous disease (CGD) is a hereditary disorder of neutrophil with defective killing and digesting of ingested catalase-positive bacteria or fungi in spite of normal phagocytosis. Dissemination of ingested live organisms results in multiple granuloma in reticuloendothelial system and multiple abscesses manifested by recurrent pus-draining suppurative lymphadenopathy, subcutanous abscess, or impetiginous skin rahses, pheumonitis, and hepatosplenomegaly, ultimately resulting in death. Two...
Original Article
Clinical Study of Group B Streptococcal Infection in Infants Less Than Two Months of Age
Hee Jeong Ahn, Ji Yeon Lim, Sung Hee Oh, In Joon Seol, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1992;35(1):17-25.   Published online January 15, 1992
Since 1970, the group B streptococcus has become significant cause of neonatal septicemia and/or meningitis, in recent years the group B streptococcus and E.coli are most common etiologic agent of septicemia and/or meningitis in infants less than two months of age. We have analized 8 cases of group B streptococcal infection who admitted to the department of Pediatrics, Hanyang University...
An epidemiologic study of measles among hospitalized pediatric patients.
Sung Lae Park, Jae Won Oh, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 1991;34(10):1356-1364.   Published online October 31, 1991
A clinical study was performed on 197 cases of measles that were admitted to the department pediatrics of Hanyang University Hospital during the period of 5 years from Aug. 1985 to Jul. 1990. The patients with measles were classified as preventable or nonpreventable. We obtained the following results: 1) The incidence of measles was greater during the last study year than the previous years. 2) The age...
A clinical study on varicella zoster virus infection and treatment in children with malignant lymphoproliferative disease.
Hak Won Kim, Jae Won Oh, Sung Hee Oh, Ha Baik Lee, Hahng Lee
Clin Exp Pediatr. 1991;34(9):1246-1254.   Published online September 30, 1991
Vaircella Zoster Virus (VZV) infection is usually a benign disease in normal hosts, but it is known to result in high risk for visceral dissemination and mortality in immunocompromised hosts, as in the children with malignant diseases, especially with malignant lymphoproliferative diseases. Therefore, passive or active immunization and antiviral therapeutic modality have been tried to control visceral dissemination and thus to decrease mortality in...
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