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Volume 41(4); Apr 1998
Clinical Lecture
Skin Rashes in Children
Jin Han Kang
J Korean Pediatr Soc. 1998;41(4):431-436.   Published online April 15, 1998
Original Articles
The Impact of Prolonged Breast Milk Feeding and Large Amount of Whole Cow's Milk Intake on Iron Status in Early Childhood
Pei Tai Wang, In-sang Jeon
J Korean Pediatr Soc. 1998;41(4):437-443.   Published online April 15, 1998
Purpose : The Large amounts of whole cow’s milk intake, just followed by prolonged breast milk feeding may induce a severe deficit of iron. We performed this study to investigate the severity of iron deficiency in these subjects. Methods : Seventy-one subjects(12 to 48 months of age) were classified according to history of prolonged breast milk feeding and intake of large amounts of whole...
A Survey of Breast-Feeding
Yun Ah Sung,, Ju Yong Ahn, Hwa Yeon Lee, Jae Yoon Kim, Don Hee Ahn, Yong Jin Hong
J Korean Pediatr Soc. 1998;41(4):444-450.   Published online April 15, 1998
Purpose : The superiority of breast-feeding to artificial feeding of infants aged 6 months or less has been well established. Due to the low rate of breast-feeding in our 1994 hospital survey we recommended and educated about breast-feeding to mothers who delivered in our hospital since January 1995. The purpose of this survey is to assess if the rate of breast-feeding increased in our...
Effect of Simultaneous Administration of Hepatitis B Vaccine with DPT and Oral Polio Vaccine
Hyo Geun Ju, Young Youn Choi, Jae Sook Ma, Tai Ju Hwang
J Korean Pediatr Soc. 1998;41(4):451-455.   Published online April 15, 1998
Purpose : The universal vaccination against hepatitis B during early infancy is the only effective way to control hepatitis B infection in highly endemic areas in Korea. The purpose of this study was to assess the effectiveness of simultaneous hepatitis B vaccination with DPT and oral polio at 2, 4, 6 months of age in babies of HBs antigen negative mothers. Methods : One...
High Frequency Oscillatory Ventilation as a Rescue Therapy of Severe Neonatal Respiratory Failure
Eun Kyung Lee, Yun Sil Chang, Won Soon Park
J Korean Pediatr Soc. 1998;41(4):456-465.   Published online April 15, 1998
Purpose : High frequency oscillatory ventilation(HFOV) using suprathysiologic ventilatory frequency is a new therapeutic technique, which has a improved survival and reduced complication of newborn infants suffering from severe respiratory failure. The aim of this study was to assess the efficacy of HFOV as a rescue therapy for infants with severe respiratory failure and to compare the treatment results...
Comparison of Continuous Versus Intermittent Infusion of Indomethacin in PDA of Preterm Infants
Yun Kyoung Lee, Hee Seok Kim, Kyoung Ran Park, Chan Hu Park, June Dong Park, Beyong Il Kim, Woong Heum Kim, Jung Hwan Choi, Chong Ku Yun
J Korean Pediatr Soc. 1998;41(4):464-470.   Published online April 15, 1998
Purpose : Patent ductus arteriosus(PDA) of prematurity is very important disease to study because it causes many cases of perinatal morbidity and its incidence is now increasing. Nowadays indomethacin is the drug of choice for PDA closure, but its use has been limited due to its side effects. Therefore, we compared the effect and side effects of indomethacin according to the infusion method, continuous...
Retrospective 3-year Clinical Study of Enterobacter Bacteremia in Neonatal Intensive Care Unit
Kwang Ok Chung, Chun Hyuk Chang, Sung Min Cho, Dong Seok Lee, Doo Kwun Kim, Sung Min Choi
J Korean Pediatr Soc. 1998;41(4):466-471.   Published online April 15, 1998
Purpose : Enterobacter is one of the important organisms in neonatal intensive care unit. We reviewed the clinical characteristics, underlying diseases, invasive procedures during admission, mortality and antibiotic sensitivity of Enterobacter infection in NICU. Methods : We retrospectively reviewed 21 neonatal patients whose blood cultures yielded Enterobacter between June 1994 and June 1997 at Dongguk University Hospital. Results : Blood cultures were positive in 62...
Preparation and in vitro Physical Activities of Crude Natural Surfactant and Artificial Pulmonary Surfactant Containing Synthetic Peptide and Phospholipid Mixtures
Joo Hyun Kang, Song Yub Shin, Cheol-Young Maeng, Kil Lyong Kim, Chong-Woo Bae, Kyung-Soo Hahm
J Korean Pediatr Soc. 1998;41(4):472-480.   Published online April 15, 1998
Purpose : In this study, natural pulmonary surfactant was extracted from bovine lung lavage and its surface activity was determined. To investigate the usefulness of synthetic peptides reconstituted with phospholipid as artificial surfactant, truncated peptides from surfactant protein (SP)-B were synthesized and restored the surface tension lowering activities when appropriately recombined with phospholipid. Methods : Crude natural surfactant(CNS) was isolated from lung lavage by centrifugation...
Phenotypic and Functional Differentiation of Promyelocytic Cell Line HL-60 by N-N-dimethylformamide
Kyung Hyo Kim, Ju Young Seoh
J Korean Pediatr Soc. 1998;41(4):481-488.   Published online April 15, 1998
Purpose : HL-60 is a promyelocytic cell line. Fcγ receptors and complement receptor 3(CR3) play important role in the protective response of granulocytes and monocytes against microbial infection. We quantified the expression of FcγI, FcγII, FcγIII, and CD11b/CD18 during differentiation using HL-60 cells by N-N-dimethylformamide(DMF). Functional studies, such as phagocytic activity, respiratory burst and ADCC, were also performed. Methods : HL-60 cells were induced to...
Study of Seroprevalence of Antimycoplasma Antibody in Healthy Children and its Diagnostic Value
Soo Kyung Choi, Ji Ah Jung, Kyung Hyo Kim, Gyoung Hee Kim
J Korean Pediatr Soc. 1998;41(4):489-497.   Published online April 15, 1998
Purpose : To evaluate the diagnostic reliability of the single serum titers of the specific serum antibody determiantion method, we compared antimycoplasma antibody titers of 177 healthy children with 353 children who had respiratory symptoms indicative of Mycoplasma pneumoniae infection. Methods : We used Serodia-Myco II particle agglutination test and the titers of ≥1:40 were regarded as positive. Results : Age distribution of 177 healthy...
A Clinical Study of Single Umbilical Artery
Mi Yeon Choi, Young Jun Kim, Young Ah Lee, Ha Joo Choi, Woo Kap Chung, Keun Young Lee
J Korean Pediatr Soc. 1998;41(4):498-504.   Published online April 15, 1998
Purpose : Single umbilical artery(SUA), the most common malformation of the umbilical cord, has long been of interest because of its association with congenital malformations. This retrospective study was aimed to evaluate the incidence of SUA and its associated malformations. Method : The study population was inborn neonates of Kang-Nam Sacred Heart Hospital of Hallym University. We reviewed retrospectively the medical records of 15...
Clinical and MRI Findings of Acute Disseminated Encephalomyelitis Associated with Preceding Infections Confirmed Serologically
Jung-Yeon Shim, Tae-Sung Ko, Hyung-Nam Moon, Chang-Yee Hong, Choong-Gon Choi,, Shi-Joon Yoo, Dae-Chul Suh
J Korean Pediatr Soc. 1998;41(4):505-513.   Published online April 15, 1998
Purpose : Acute disseminated encephalomyelitis(ADEM) is an inflammatory demyelinating disease of the central nervous system. The pathogenesis is not well known, but it is thought to be an immune-mediated disease and may follow a viral infection or vaccinations. MRI demonstrates decreased signal on T1 weighting and increased signal on T2-weighted image. We report clinical features and characteristic MRI findings in seven patients with ADEM...
Milk Feeding Methods and the Changes of Serum Lactate Level in Infants with Iron Deficiency Anemia
Du Young Choi, Jong Duck Kim
J Korean Pediatr Soc. 1998;41(4):514-520.   Published online April 15, 1998
Purpose : Infants undergo critical and rapid stages of growth. Optimal nutrition during this period is therefore essential. Iron deficiency is especially impotant and common. The aim of this study was to determine the present status and problems of milk feeding methods in infants with iron deficiency anemia and, futhermore, to develop appropriate feeding guidelines for adequate iron nutrition. Latate is the end product...
A Clinical and Histological Study of Allergic Colitis in Infant
Jae Bok Kim, Kyung Mo Kim, Ki Soo Kim, Soo Young Pi, Yang Soon Park
J Korean Pediatr Soc. 1998;41(4):521-528.   Published online April 15, 1998
Purpose : This study was done to evaluate the clinical and pathologic aspects of allergic colitis. Methods : This study evaluated 19 infants who presented with fresh blood mixed stools. Limited colonoscopy and biopsy were performed. Among the 19 infants, 13 infants were diagnosed as allergic colitis by histological findings. We analyzed the clinical and histological characteristics of 13 infants. Results : Male and female...
Case Reports
Two Cases of Wolman's in Siblings
Joon Sung Kim, Tai Huyng Cho, Hoon Kook, Seung Hee Choi, Young Youn Choi, Chang Soo Park, Heoung Keun Kang, Dong Kyu Jin, Tai Ju Hwang
J Korean Pediatr Soc. 1998;41(4):529-537.   Published online April 15, 1998
Wolman' disease is a rare autosomal recessive disorder in which a deficiency of lysosomal acid lipase leads to the accumulation of cholesteryl esters and trigycerides in most of the body tissues. Clinically, it is characterized by abdominal distention, hepatosplenomegaly, vomiting, intractable diarrgeam steatorrhea, malabsorption, inanitionm failure to thrive, and bilateral enlargement and calcification of the adrenal glands demonstrated by roentgenographic...
Magnetic Resonance Angiography in One Case of Hydraencephaly
Eun Kyung Hwang, Kang Ho Cho, Gwang Hoon Lee, Gil Hyun Kim, Hak Soo Lee, Ji Hye Kim, Young Seok Lee
J Korean Pediatr Soc. 1998;41(4):538-542.   Published online April 15, 1998
In hydranencephaly, the cerebral hemispheres are absent or represented by membranous sacs with remnants of frontal, temporal or occipital cortex dispersed over the membrane. The brain stem is relatively intact. The cause of hydranencephaly is unknown, but bilateral occlusion of the internal carotid arteries during early fetal development can explain most of the pathologic abnormalities. We evaluated a case of hydranencephaly by magnetic resonance(MR)...
A Case of Berry Syndrome associated with Syndactyly
Sang Chun Jung, Kyoung Sim Kim, Yong Wook Kim, Ki Bok Kim
J Korean Pediatr Soc. 1998;41(4):543-547.   Published online April 15, 1998
Berry syndrome is a rare association of congenital heart anomalies which consists of a distal aortopulmonary window with aortic origin of the right pulmonary artery and hypoplasia or interruption of the aortic arch. This defect can be corrected only by immediate surgical intervention, so accurate preoperative diagnosis and detailed anatomic depiction of this syndrome are important in prognosis. We experienced a case of Berry...
Fatal Doudenal Ulcer Bleeding in Status Asthmaticus Treated with Theophylline and Steroids
Sang Woo Lee, Chang Keun Kim, Churl Young Chung, Young Doug Kim
J Korean Pediatr Soc. 1998;41(4):548-552.   Published online April 15, 1998
It is generally agreed that theophylline preparations and steroids should be given intravenously for status asthmaticus. Theophylline can potentially have adverse gastrointestinal effects including abdominal pain, nausea, vomiting, and hematemesis. Upper gastrointestinal bleeding in patients treated with corticosteroids without a past history of upper gastrointestinal bleeding has been reported rarely. But the etiologic significance of the stress of status asthmaticus, administration of theophylline or corticosteroids...
A Case of Unilateral Diaphragmatic Paralysis with Brachial Plexus Palsy in the Neonate
Hae Joong Yoon, Kyeung Ho Park, Sang Hee Kim, Kye Whan Seul, Gil Hyun Kim, Hak Soo Lee, Chang Young Lim
J Korean Pediatr Soc. 1998;41(4):553-557.   Published online April 15, 1998
The diaphragm is especially important in sustaining minute ventilation in the neonate. Consequently, diaphragmatic paralysis is not tolerated well by the neonate and often results in prolonged respiratory failure. We experienced a case of unilateral diaphragmatic paralysis with the brachial plexus palsy in a male newborn infant who presented with apnea and cyanosis due to birth asphyxia. After endotracheal intubation, mechanical ventilaton was started....
A Case of Bilateral Vocal Cord Paralysis in Neonate
Young Kyoun Kim, Seung Cheol Lee, Se Wook Oh, Sang Woo Kim, Jae Hyung Park
J Korean Pediatr Soc. 1998;41(4):558-561.   Published online April 15, 1998
Neonatal vocal cord paralysis is the second most common laryngeal anomaly, which accounts for approximately 10% of all congenital laryngeal lesions. Neonate with bilateral vocal cord paralysis are charactenzed with a glottic obstruction which usually shows dyspnea and inspiratory stridor. Treatment of bilateral vocal cord paralysis in neonate have two major goals : restore proper breathing and retain the voice. Tracheostomy is the best...
A Case of Crohn's Disease Diagnosed After Appendectomy
Hee Yeoun Kim, Hae Jin Lee, Hae Sun Kim, Jeong Wan Seo, Woon Sup Han, Sun Wha Lee
J Korean Pediatr Soc. 1998;41(4):562-567.   Published online April 15, 1998
Crohn’s disease is a chronic inflammatory disease that may affect any part of the gastrointestinal system and multiple extraintestinal organs. Right lower quadrant abdominal pain with fever may be mistaken as a acute appendicitis. Pancreatitis has rarely been reported as a complication of Crohn’s disease. However, we experienced one case of Crohn’s disease with pancreatitis : the histologic examination after appendectomy of a 12-year-old...
Two Childhood Cases of Heat Stroke with Rhabdomyolysis and Multiorgan Failure
Yang-Suk Jung, Jae-Young Lim, Yun-Kyeong Cho, Gye-Woo Yi, Chan-Hoo Park, Hyang-Ok Woo, Hee-Shang Youn
J Korean Pediatr Soc. 1998;41(4):568-573.   Published online April 15, 1998
Heat stroke occurs when body thermal regulation is upset and unable to dissipate adequate amounts of heat with rise in body temperature. Thus heat stroke may result in rhabdomyolysis and multiorgan failure. We observed two childhood cases of heat stroke with rhabdomyolysis and multiorgan failure. One case was caused by accidentally being left in a car trunk for 3 hours on a sunny afternoon...