Purpose : Internal tibial torsion is prevalent in East Asian countries such as Korea and Japan, where sitting on the floor is common behavior. Internal tibial torsion or excessive lateral tibial torsion may cause esthetical, functional, or psychological problems and also may induce degenerative arthritis in older age. The purpose of this study is to measure the tibial torsion in... |
Purposes : A cross-sectional study on serum lipids in school children and adolescents was carried out in two different areas in 2002. We studied to determine of the difference in lipids level of children between urban and rural areas and changes of cholesterol levels compared to those of early- 1990 studies. Methods : A cross-sectional study on serum lipids in school... |
Purpose : Pharmacologic provocation test of growth hormone(GH) is a non-physiologic method and has several limitations for diagnosing growth hormone(GH) deficiency. Spontaneous GH release studies could be important in understanding the pathophysiology of children with poor growth but normal responses to GH provocation tests. Also, the relationship between nocturnal GH secretions and sleep patterns in short stature children is poorly... |
Purpose : This study was undertaken to investigate changes in cardiac performance in early neonatal life by observing the changes of left ventricular(LV) function and volume according to the size of ductus arteriosus. Methods : The study group consisted of 21 full-term Cesarean section neonates who were admitted to the nursery of Korea University Hospital. We serially investigated the... |
Kabuki make-up syndrome(KMS) is characterized by mental and developmental retardation and peculiar facial features including long palpebral fissures with eversion of the lateral portion of lower eyelid and arching of eyebrows, resembling the actors in Japanese Kabuki. In addition, dermatoglyphic and skeletal abnormalities are commonly associated. Although most karyotypes of KMS are shown to be normal, there have been some... |
Purpose : Menstrual disorders are very common problems in adolescence. Most of them are minor, including mild dysmenorrhea, premenstrual syndrome(PMS) and minor variations in cycle, length, or amount of flow. Dysmenorrhea is the most prevalent among them while PMS is a nebulous condition characterized by a broad spectrum of symptoms. The purpose of this study is to investigate the correlation... |
Purpose : Retinoic acid(RA) is well known as a potent teratogenic agent in both deficiency and excess. Cellular retinoic acid binding proteins(CRABPs) are involved in RA. We carried this study in order to determine the possible relations of CRABPs with RA-induced teratogenesis through observation of the expression patterns of CRABP Ⅰand Ⅱ in developing rats. Methods : 35S-labeled RNA probes were... |
Purpose : This study was performed to evaluate seropositivities in term pregnant women and their neonates, and the transplacental transfer rate of maternal mumps and rubella- specific IgG from term pregnant women to their neonates. Methods : During Jun. 1, 1994 to Mar. 31. 1995, we collected 44 pairs of sera from pregnant women and their neonates in Anam Hospital of Korea University Medical... |
Purpose : School-based violence among adolescents is a serious public health problem. Recently, it seems to spread and intensify. We were trying to investigate the information about adolescent' s experience, witness and perception in violence, thus to offer the data for appropriate violence prevention methods on our circumstance. Methods : During July, 1996, 3,794 middle or high school students in the metropolitan area of Korea... |
Familial Hypercholesterolemia is the most common hyperlipoproteinemia during the childhood, which occurs from the mutation of genes that regulates low-density lipoproteins(LDL), and is classified into two types, the homozygote presented abnormal genes from both parents and the heterozygote presented an abnormal gene from each parent. Type IIa familial hypercholesterolemia is characterized by, especially, increased level of LDL which is common type and normal level... |
Purpose : Menarche is an important life event, making the transition from childhood to early womanhood. It is a significant physical and physiological event that adolescent girls feel sexual identity and it affects on psychological development. The onset of menstruation is considered a practical indication of sexual maturity in girls. On a population level, mean menarcheal age is considered to... |
Purpose : Recently, smoking and alcohol use in adolesecnt have increased and it has been a social issue in Korea.This study was performed to understand the state of smoking and alcohol use in Korean adolescents, and to make abasic data for education of them. Methods : This study was carried in 1994.3,360 students in 13 schools aged from 13 to 18 were enrolled in this... |
Purpose : Despite appropriate preventive measures, measles outbreaks occurred in the year of 1989-1990 and 1994 in Korea. Especially, the ratio of young infantile patients below 15 months old was high in those outbreaks, and the reason was, we thought, low serum level of measles specific IgG antibody in pregnant women and low transplacental transfer rate of measles specific IgG antibody to neonate. This... |
Purpose : Despite preventive measures, measles outbreaks ocurred in 1989, 1990 and 1994 in Korea. Especially, the proportion of immunized school aged children and adolescents was increased, and the reason was, in our opinion, primary and secondary vaccine failure after measles immunization. In this context, we attempted to evaluate the changes of measles specific IgG levels in various age groups of... |
Purpose : After recent epidemics of measles in Korea, Korean Pediatric Society recommended 2 dose measles vaccination schedule instead of 1 dose since 1991. However, the studies that supported the modification of vaccination schedule were insufficient yet. This study was performed to evaluate the vaccination efficacy of 1 dose and 2 dose vaccination. Methods : One dose vaccination group consisted of 19 infants(mean:... |
Purpose : Plasma fibronectin is thought to have important role in the inflammatory response and host defense. We performed this study to evaluate concentration in the full-term, healthy preterm, asphyxia and respiratory distress syndrome and how that correlated with gestational age and birth weight. Methods : We evaluate 51 neonates who were delivered at Korea University Hospital from Jan. 1992 to... |
Chronic pancreatitis is a rare problem in childhood and sometimes shows pancreatic calcif-ication. The most common symptom is chronic recurrent upper abdominal pain, with waves of crampy pain that increase in severity, with or without associated nausea or vomiting. Although the diagnosis is made or considered infrequently hereditary or other metabolic factors, the cau-se remains largely idiopathic. Endoscopic retrograde cholangiopancreatography(ERCP)... |
Purpose : Adrenocorticotropic Hormone(ACTH) therapy is useful in the treatment of patients with infantile spasm. However, serious side effects including Cushing syndrome, infections, hypertension, and electrolyte imbalance must be encountered. Moreover, hypertrophic cardiomyopathy in association with ACTH therapy has recently reported. We performed thiw study to evaluate the effect of ACTH on heart muscle. Methods : We administered ACTH subcutaneously to... |
Lipoprotein(a) [Lp(a)] is considered an additional, independent and largely genetically determined risk factor for the development of premature coronary heart disease. Furthermore abnormal plasma lipoprotein patterns have been associated with increased risk for developing coronary heart disease. Among these lipoproteins, an increased concentration of serum Apo B and decreased level of Apo A are considered as major risk factors, together... |
Iron deficient state occurs commonly in the athlets, and the cause may be cause may be inadequate iron intake, loss of iron from sweat, blood loss of gastrointestinal tract, and hematuria. The age of the athletes ranged from 11 to 17 years old. I messured red blood cell count, hemoglobin, hematocrit, and related hematologic factors in the 32 adolescent female... |
The long term administration of anti-convulsants on children with convulsive disorders may cause osteomalacia, depending on the dosage, duration, type and combination of anti-convulsants administred. Fifteen children, comprising 10 male and 5 female, dignosed with convulsive disorders and administered with phenobarbital for a long term period of more than 9 months but less than 84 months and 15 healthy children... |
We report a cases of solid and papillary neoplasm of the pancreas, which is a rare pancreatic tumor. We described clinical characteristics, sonographic, computed tomographic and pathologic finding. The tumors had a smooth, enhanced capsule and variable internal architecture. The tumor was distributed tail of pancreas without local invasion. The origin of the tumor is probably from a multipotential stem... |
Endotheline-1(ET-1) is a potent vasoconstrictor peptide with 21 amino acid residues. ET-1 is thought to have a key role in vasoconstriction, and cardiac, renal, and endocrine actions of the peptide. Creatine Kinase(CK), also referred to as ATP-creatine-N-phosphotransferase, consists of either the B or M type. CK is found almost exclusively in muscle (MM), myocardium (MB), and brain (BB). It is... |
The clinical symptom complex characterized by syncopal attacks and sudden death in patients with electrocardiographic anomalies, especially a prolonged Q-t interval is known as the Romano-Ward syndrome. When a similar syptom complex is accompanied by congenital deafness, it is called Jervell and Lange-Nieisen syndrome. This study was underataken to investigate the incidence of the latter syndrome in the... |
Fetal hydrops is often serious and associated with a high perinatal motality rate. Cardiac causes of fetal hydrops include congenital heart diseases and rhythm disturbances. An irregular fetal heart rate may indicate atrial fibrillation and atrial flutter with variable AV conduction. Fetal atrial flutter is characterized by the pressence of flutter waves which are regular sawtooth undulations in the baseline that... |
Dyke-Davidoff Masson syndrome is a rare disorder which developed hemiatrophy of brain, enlargement of ventricles and prominet pneumatrization of pertous pyramid of the temporal bone. It manifests hemiparesis, varying type seizure, and mental retardation. We experienced two cases of Dyke-Davidoff-Masson Syndrome, in a 6/12 year-old boy and a 1,10/12 year-old girl who were admitted to our department of pediatrics, because of... |
Eight neonates with transient tricuspid insufficiency are presented which was confirmed clinical and two dimensional echocardiographic assessment. We found that two dimensional Doppler echocardiography was very useful in the detection of transient tricuspid insufficiency during neonatal age as noninvasive method. Transient tricuspid insufficiency is a clinical disorder in the newborn period caused by myocardial dysfunction, secondary to asphyxia with or without... |
Obesity has been implicated as a significant risk factor for multiple medical condition including hypertention, glucose intolerance, hyperlipidemia, hyperisulinemia and fatty liver. Furthermore, obesity in childhood is believed to be a reliable predictor of a similar condition in adulthood. During the recent yars, there has been a rapid rise in the incidence of childhood obesity in Korea due to increased... |
Our study surveyed 418 obese first grade elementary school children (279 male and 139 female), in seoul, and measured levels of serum total cholesterol, HDL Cholesterol, LDL cholesterol, triglyceride were measured in addition to the measurement of body weight and height. The following results were obtained. 1) Obesity index was catergorized into mild, moderate, and severe, and the percentage of mild was... |
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