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- Original Article
- Adolescence Medicine
- Serum alanine aminotransferase levels are closely associated with metabolic disturbances in apparently healthy young adolescents independent of obesity
- Ki Eun Kim, Kyung Suk Baek, Sol Han, Jung Hyun Kim, Youn Ho Shin
- Clin Exp Pediatr. 2019;62(2):48-54. Published online November 23, 2018
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Purpose: Liver metabolism plays a pivotal role in the development of metabolic disorders. We aimed to investigate the clinical and laboratory risk factors associated with alanine aminotransferase (ALT) levels in young adolescents from an urban population in Korea. Methods: A population of 120 apparently healthy adolescents aged 12–13 years was included in the cross-sectional design study; 58 were overweight or obese...
- Endocrinology
- Final height of Korean patients with early treated congenital hypothyroidism
- Jiyun Lee, Jeongho Lee, Dong Hwan Lee
- Clin Exp Pediatr. 2018;61(7):221-225. Published online July 15, 2018
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Purpose: Congenital hypothyroidism (CH) is the most common endocrine disorder in children. Thyroid hormone deprivation results not only in mental retardation but also growth retardation. This study investigates the final height (FH) in Korean patients with CH detected by newborn screening and examines factors that may affect the FH. Methods: The medical records of Korean CH patients (n=45) were reviewed. The...
- Change in the height of Korean children and adolescents: analysis from the Korea National Health and Nutrition Survey II and V
- Na Yung Ryoo, Ha Young Shin, Jae Hyun Kim, Jin Soo Moon, Chong Guk Lee
- Clin Exp Pediatr. 2015;58(9):336-340. Published online September 21, 2015
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Purpose The mean adult height of Koreans has increased since nationwide anthropological measurements began in 1967. The objective of this study was to evaluate differences in heights of Korean late adolescents and young adults within and between the Second and Fifth Korea National Health and Nutrition Examination Surveys (KNHANES II and V).
Methods Koreans aged ≤22 years with available measurements of height were...
- The correlation of blood pressure with height and weight in Korean adolescents aged 10-19 years; The Korean National Health and Nutrition Examination Surveys (2009-2011)
- Young-Hwan Song
- Clin Exp Pediatr. 2014;57(1):35-40. Published online January 31, 2014
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Purpose Height-specific blood pressure (BP) is the standard parameter used to diagnose childhood hypertension. However, there has been some argument that weight may be a better variable than height in the reference BP standards. Therefore, before assessing the BP status using the reference BP standards, a basic understanding of the fundamental association of weight and height with BP is required.
Methods In the...
- Review Article
- Secular trends of body sizes in Korean children and adolescents: from 1965 to 2010
- Jin Soo Moon
- Clin Exp Pediatr. 2011;54(11):436-442. Published online November 30, 2011
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An anthropometric survey is one of the most important approaches to use when evaluating the health status of children. Secular trends in body sizes, such as height, weight, head circumference, chest circumference, and body mass index showed significant changes over 40 years in Korea. A series of periodic surveys were conducted in 1967, 1975, 1985, 1997, and 2005 by the...
- Original Article
- Final height of patients with congenital heart disease
- Soon Ju Lee, Young Kuk Cho, Jae Sook Ma
- Clin Exp Pediatr. 2010;53(2):203-209. Published online February 15, 2010
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Purpose : Growth impairment is usually observed in children with congenital heart disease (CHD). Studies on the final height and weight of this population are insufficient. Our aim was to evaluate the final height of children with CHD and to identify the relationship between CHD and growth. Methods : We recorded the values of final height and weights of 105 CHD... -
- Questionnaire-based analysis of growth-promoting attempts among children visiting a university growth clinic
- Kyoung Huh, Mi Jung Park
- Clin Exp Pediatr. 2009;52(5):576-580. Published online May 15, 2009
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Purpose : Growth-promoting attempts are widespread in Korea, but little is known about their prevalence or associated factors. This study was designed to assess the prevalence of growth-promoting attempts among children visiting a university growth clinic. Methods : A questionnaire-based survey was carried out with 823 children (416 boys, 407 girls) who visited the growth clinic at Paik Hospital. Results... -
- Comparison of predicted adult heights measured by Bayley-Pinneau and Tanner-Whitehouse 3 methods in normal children, those with precocious puberty and with constitutional growth delay
- Yeon Joung Oh, Byung Keun Yu, Jung Yeon Shin, Kee-Hyoung Lee, Kwang Chul Lee, Chang Sung Son
- Clin Exp Pediatr. 2009;52(3):351-355. Published online March 15, 2009
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Purpose : This study compared bone ages measured by the Greulich-Pyle (GP) and Tanner-Whitehouse 3 (TW3) methods and investigated the differences in predicted adult heights measured by Bayley-Pinneau (BP) and TW3 methods. Methods : Bone ages were assessed from left-wrist radiographs by two investigators, one for each GP and TW3 methods in 85 normal children, 30 precocious puberty girls, and... -
- The long-term follow-up of height in children with epilepsy
- Ju Hee We, Sang Ook Nam
- Clin Exp Pediatr. 2008;51(10):1090-1095. Published online October 15, 2008
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Purpose : To assess the height growth of children with epilepsy receiving antiepileptic drugs (AEDs) and the related factors. Methods : The subjects were 148 children diagnosed with epilepsy at Pusan National University Hospital between January 1996 and December 2003, who received AEDs for more than 3 y. We measured height at the initiation of AED medication and at the... -
- A study on the attitudes of middle school students concerning height
- Won Derk Lee, Jae Wook Lieu, Jun Wha Lee, Joo Seok Lee, Kyung Lae Cho
- Clin Exp Pediatr. 2008;51(3):248-255. Published online March 15, 2008
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Purpose : The purpose of this study was to evaluate the attitudes of middle-school students about height and their behaviors related to height gain. Methods : One thousand four hundred twenty two middle-school students were included. We requested that the students complete a battery of questionnaires asking about problems associated with height. Results : There was a clear difference between... -
- Review Article
- 2007 Korean National Growth Charts: review of developmental process and an outlook
- Jin Soo Moon, Soon Young Lee, Chung Mo Nam, Joong-Myung Choi, Bong-Keun Choe, Jeong-Wan Seo, Kyungwon Oh, Myoung-Jin Jang, Seung-Sik Hwang, Myung Hwan Yoo, Young Taek Kim, Chong Guk Lee
- Clin Exp Pediatr. 2008;51(1):1-25. Published online January 15, 2008
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Purpose : Since 1967, The Korean Pediatric Society and Korean Government have developed Korean Growth Standards every 10 years. Last version was published in 1998. During past 40 years, Korean Growth Standards were mainly descriptive charts without any systematic nor statistical standardization. With the global epidemic of obesity, many authorities such as World Health Organization (WHO) and United States' Centers... -
- Original Article
- Growth promoting effect of short-term gonadotropin releasing hormone agonist with or without growth hormone in girls with early puberty
- Eun-Ju Lee, Heon-Seok Han
- Clin Exp Pediatr. 2007;50(2):198-204. Published online February 15, 2007
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Purpose : The hope that arresting pubertal developement might increase final adult height has led to an attempt to use GnRH agonist (GnRHa) in children with early puberty and poor growth prognosis. We investigated the growth-promoting effect of GnRH agonists with or without growth hormone (GH) in girls with early puberty and decreased predicted adult height (PAH). Methods : Thirty five... -
- A study and the growth and the development of microvascular complications in patients with type 1 diabetes mellitus
- Young Ah Lee, Kyong-Ah Yun, Choong Ho Shin, Sei Won Yang
- Clin Exp Pediatr. 2007;50(2):190-197. Published online February 15, 2007
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Purpose : Reduced growth and microvascular complications have been recognized as consequences of type 1 diabetes mellitus (T1DM). We assessed the effect of T1DM on growth and factors associated with the development of microvascular complications. Methods : We conducted a retrospective longitudinal evaluation of 154 patients above 16 years of age. We analyzed factors which affect final height standard deviation scores... -
- Factors affecting the final adult height in survivors of childhood brain tumors
- Kyong-Ah Yun, Young Ah Lee, Choong Ho Shin, Sei Won Yang, Hee Young Shin, Hyo Seop Ahn, Il Han Kim
- Clin Exp Pediatr. 2007;50(1):65-73. Published online January 15, 2007
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Purpose : Short stature is an important complication that impairs the quality of life in survivors of childhood brain tumors. We studied their final adult height (FAH) to evaluate risk factors for short stature. Methods : We reviewed the medical data of 95 survivors of childhood brain tumors (64 males and 31 females) who had been followed up from 1982 to... -
- Effect of GnRH analogue on predicted adult height in girls with early puberty
- Byung-Hoon Ahn, Heon-Seok Han
- Clin Exp Pediatr. 2006;49(5):552-557. Published online May 15, 2006
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Purpose : The recent results observed in precocious puberty and the hope that interrupting puberty might increase adult height have led to an attempt to use GnRH agonist(GnRHa) in children with premature puberty and a poor growth prognosis. We aimed to analyze the growth promoting effect of GnRHa in girls with early puberty and low predicted adult height(PAH). Methods : Thirty... -
- Effects of Growth Hormone Therapy in Children with Idiopathic Short Stature
- Kyong A Lee, Heon Seok Han
- Clin Exp Pediatr. 2005;48(8):865-870. Published online August 15, 2005
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Purpose : The use of growth hormone(GH) to promote growth in normal short children without classical GH deficiency is controversial. Numerous foreign studies have shown the effects of GH therapy in children with idiopathic short stature(ISS) whereas few has been interested in Korea. Therefore, this study is designed to investigate the effects of GH therapy on ISS by observing correlations... -
- Factors Affecting Final Adult Height in Patients with Turner Syndrome
- Jae Hyun Kim, Sung Soo Lee, Su Young Hong, Hye Rim Chung, Choong Ho Shin, Sei Won Yang
- Clin Exp Pediatr. 2005;48(2):191-196. Published online February 15, 2005
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Purpose : Short stature is one of the characteristic features of Turner syndrome. We investigated the factors affecting final adult height(FAH) in patients with Turner syndrome. Methods : The study group was comprised of 60 patients who were diagnosed with Turner syndrome by chromosomal study and clinical phenotypes and attained FAH. Data were obtained from retrospective review of the medical records.... -
- The Effects of Gonadotropin-Releasing Hormone Agonists on Final Height and its Related Factors in Patients with True Precocious Puberty
- Sung Yeon Ahn, Jae Ho Yoo, Choong Ho Shin, Sei Won Yang
- Clin Exp Pediatr. 2004;47(6):647-655. Published online June 15, 2004
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Purpose : The aim of this study was to evaluate the effects of treatment with GnRH agonists on final height(FH) and the influencing factors on height gains. Methods : Twenty-five girls and five boys with true precocious puberty, who were treated with GnRH agonists for more than one year and had attained final height, were evaluated retrospectively. We analysed auxological parameters... -
- The Effect of Growth Hormone on Patients with Growth Hormone Deficiency and Idiopathic Short Stature
- Jeong Cheol Kang, Yoon Suk Choi, In Kyong Choi, Ho Sung Kim, Duk Hee Kim
- Clin Exp Pediatr. 2004;47(3):310-318. Published online March 15, 2004
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Purpose : This study was designed to evaluate the effect of growth hormones on children with growth hormone deficiency(GHD) or idiopathic short stature(ISS). Methods : Between January 1988 to July 2003, 45 patients(M26, F19) with GHD and 24 patients (M13, F11) with ISS were enrolled in this study. Height standard deviation score(Ht SDS) for chronological age(CA) and Ht SDS for bone... -
- The Relationship between the Perception of Height and Self-Esteem in Children
- Mi Jin Kim, Young Il Rho, Eun Seok Yang, Kyung Rye Moon, Sang Kee Park, Yeong Bong Park, Eun Young Kim
- Clin Exp Pediatr. 2004;47(3):258-263. Published online March 15, 2004
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Purpose : The aim of this study was to evaluate the behavioral and affective characteristics of children who thought they were short. Methods : Fifteen hundred and twenty-two students of four elementary and middle schools in Gwangju City completed a battery of questionnaires asking about stature-related stress, self-esteem, and personality characteristics. The children were divided into three groups and compared according... -
- Factors Affecting on Final Adult Height and Total Height Gain in Children with Idiopathic and Organic Growth Hormone Deficiency after Growth Hormone Treatment
- Im Jeong Choi, Jin Soon Hwang, Choong Ho Shin, Sei Won Yang
- Clin Exp Pediatr. 2003;46(8):803-810. Published online August 15, 2003
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Purpose : The purpose of this study was to evaluate the factors affecting the final adult height and total height gain in idiopathic and organic growth hormone deficient(GHD) children after growth hormone(GH) treatment. Methods : Thirteen patients with idiopathic GHD and 22 patients with organic GHD who had been treated with GH and attained adult final height were included in this... -
- Factors Affecting the Presence of Menarche and Final Adult Height in Adult Female Patients with Congenital Adrenal Hyperplasia of 21-Hydroxylase Deficiency
- Seong Yong Lee, Chae Kyoung Song, Min Ho Jung, Jin Soon Hwang, Sei Won Yang
- Clin Exp Pediatr. 2001;44(1):75-82. Published online January 15, 2001
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Purpose : Amenorrhea and short stature are serious complications in patients with congenital adrenal hyperplasia of 21-hydroxylase deficiency(CAH). We analysed several factors influencing the presence of menarche and final adult height in these patients. Methods : We retrospectively reviewed medical records of 24 female patients with CAH. We analysed possible factors affecting the menarche and final adult height, such as clinical... -
- Final Height in Idiopathic Growth Hormone(GH) Deficient Children Treated with GH
- Byung Churl Lee
- Clin Exp Pediatr. 1999;42(6):852-857. Published online June 15, 1999
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Purpose : Improved adult height is a major goal in the treatment of children with short stature due to GH deficiency(GHD). The purpose of this study was to evaluate final height in idiopathic GH deficient children after long-term GH treatment Methods : GHD was diagnosed in 9 male patients by at least two stimulation tests(maximum GH level≤5ng/ml). Other pituitary functions were... -
- The Effect of Long-Acting Gonadotropin-Releasing Hormone (GnRH) Analog on the Growth Velocity and Final Adult Height in the Children with True Precocious Puberty
- Sei Won Yang, Hyung Ro Moon
- Clin Exp Pediatr. 1994;37(3):309-316. Published online March 15, 1994
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The final adult height in the children with true precocious puberty are destined to be short due to excessive bone maturation, compared to the growth velocity, regardless of its etiologies. To improve this final shortness, long-acting GnRH analog have been tried to the children with true precocious puberty. We evaluated the parameters of the growth, including the growth velocity, height... -
- The Correlation between the Bone Age and Predicted Adult height, Final Adult Height in the Children with Congenital Adrenal Hyperplasia, Especially 21-Hydroxylase Deficiency
- Sei Won Yang, Hyung Ro Moon
- Clin Exp Pediatr. 1994;37(3):300-308. Published online March 15, 1994
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We studied the correlation between the bone age and the predicted adult height, final adult height in the 69 children (30 salt losing form and 39 non-salt losing form) diagnosed as 21-hydroxylase deficiency, retrospectively. The results were as belows; 1) The bone age was similar to the chronological age in the children with salt-losing form (5.3±3.5 years, respectively), but the bone age... -
- Growth Pattern and Final Height in Congeital Adrenal Hyperplasia
- Ho Seong Kim, Duk Hi Kim
- Clin Exp Pediatr. 1993;36(10):1359-1365. Published online October 15, 1993
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Clinical characteristics and growth pattern were evaluated in 42 patients with classical congenital adrenal hyperplasia treated since diagnosis. And final height was evaluated in 16 patients who had reached final adult height with regard to clinical form, degree of hormonal control, and age of initial treatment. The results were as follows; 1) Among 42 patients with classical congenital adrenal hyperplasia, the male... -
- The Effect of Long-Term Corticosteroid Treatment on Height Velocity in Childhood
- Byung Mun Lee, Chan Yung Kim
- Clin Exp Pediatr. 1993;36(2):185-194. Published online February 15, 1993
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The auther analysed 29 patients who were treated with prednisolone, including nephrotic syndrome(13 cases). Acute leukemia (10 cases), bronchial asthma(2 cases), juvenile rheumatoid arthritis(2 cases) and ulcerative colitis(1 cases) patients in childhood, after remission induction, prolonged alternate or interrupted treatment was used. The auther observed patterns of height velocity of these patients from 1.6 to 10.3 years. The results were as... -
- Estimation of Glomerular Filtration Rate from Plasma Creatinine and Height in Premature and Fullterm Neonates.
- Yeong Jee Kim, Keun Lee
- Clin Exp Pediatr. 1986;29(7):723-729. Published online July 31, 1986
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In clinical practice, creatinine clearance(Ccr) remains the most commonly used laboratory assessment of glomerular function despite methodological and technical problems of urine collection. Schwartz et al. in 1976，reported that an accurate estimate of glomerular filtration rate (GFR) could be obtained from the simple determinations of plasma creatinine (Per) and body length(L):GFR(ml/min/1.73cm2)=k• L(cm)/Pcr(mg/100ml), (k=constant). The purpose of this investigation is to compare... -
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