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Original Article
Serum Albumin Concentrations and Clinical Disorders by Gestational Ages in Preterm Babies
Mia Lee, Soo Youn, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 2005;48(2):148-153.   Published online February 15, 2005
Purpose : The aim of this study was to determine the reference ranges of serum albumin levels depending on the gestational ages of preterm infants. We also intended to compare the mean serum albumin levels between groups of preterm infants that did not develop clinical disorders later, and groups that did develop clinical disorders such as respiratory distress syndrome, intraventricular...
Case Report
A Case of Vascular Leak Syndrome During Induction Chemotherapy of Acute Lymphoblastic Leukemia(T Cell Type)
Kye Wool Kang, Hwang Min Kim, Won Kyu Choi, Baek Keun Lim, Chang Hun Lee
Clin Exp Pediatr. 2001;44(9):1041-1046.   Published online September 15, 2001
Vascular leak syndrome(VLS) is characterized by endothelial damage, which causes extravasation of plasma proteins and fluid from capillaries into the extravascular space. It has been suggested that the increased vascular permeability is the result of an IL-2-induced suppression of endothelin- 1 secretion by endothelial cells, an IL-2-induced activation of the complement cascade or TNF-αrelease from IL-2-activated T-cells. A 13-year-old male patient visited our hospital...
Original Article
Mean Corpuscular Hemoglobin Concentration as a Discriminating Tool between Hereditary Spherocytosis and Intravascular Hemolysis
Hae Young Park, Hwang Min Kim, Kyoung Ah Lee, Dong Il Won, Sei Myeng Park, Seok Won Park, Baek Keun Lim, Kil Young Kim
Clin Exp Pediatr. 2001;44(6):664-668.   Published online June 15, 2001
Purpose : The purposes of this study were to elucidate the diagnostic significance of mean corpuscular hemoglobin concentration(MCHC) for various kinds of hemolytic anemia, the mechanism of elevated MCHC in hereditary spherocytosis(HS). Methods : The subjects consisted of 39 cases of HS(group 1), 31 cases of intravascular hemolysis (IH) such as DIC, snake bite or hemolytic uremic syndrome(group 3), and sex...
Case Report
A Case of Propionic Acidemia
Woo Seop Yeoum, Kwang Wook Lee, Byeong Ho Chae, Baek Keun Lim, Hong Jin Lee
Clin Exp Pediatr. 1999;42(8):1159-1164.   Published online August 15, 1999
Propionic acidemia is an autosomal-recessive inborn error of branched-chain amino acid metabolism. It is caused by deficient activity of propionyl-coenzyme A carboxylase and is characterized by a spectrum of clinical and biochemical findings. It usually manifests in the neonatal period or early infancy. Since Childs et al first described the propionic acidemia of infants in 1961, it has rarely been...
A Case of Idiopathic Hypoparathyroidism Associated with Graves' Disease
Eun Young Jang, Hwang Min Kim, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1999;42(5):716-721.   Published online May 15, 1999
Graves' disease is a relatively rare endocrinologic disorder in childhood age and often associated with other endocrinologic disorders such as type I diabetes mellitus and Addison's disease etc. Also, it is associtated with non-endocrinologic autoimmune diseases such as systemic lupus erythematosus, myasthenia gravis, idiopathic thrombocytopenic purpura, vitiligo and pernicious anemia. However, idiopathic hypoparathyroidism associated with Graves' disease is very...
Original Article
Diagnostic Value of Reticulated Platelet in Thrombocytopenia
Song Hee Park, Hwang Min Kim, Baek Keun Lim, Young Hak Shim, Chang Hoon Lee, Myung Seo Kang
Clin Exp Pediatr. 1997;40(6):850-856.   Published online June 15, 1997
Purpose : We performed this study to determine the diagnostic significance and useful cut-off value of reticulated platelet, which can be used for discriminating the destructive thrombocytopenia from underproductive thrombocytopenia. Methods : We evaluated 37 patients with thrombocytopenia who were admitted to the Wonju christian hospital from March to July, 1995. All patients were evaluated with bone marrow megakaryocyte count. We divided them into two...
Case Report
A Case of Multicystic Encephalomalacia in a Liveborn Twin with a Stillborn Co-twin
Mi Ya Park, Kyung Hee Kim, Jae Seung Yang, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1997;40(3):429-433.   Published online March 15, 1997
Multicystic encephalomalacia is the condition defined anatomically by the presence of multiple cavities in the great part of both cerebral hemispheres. The most common cause of the condition was regarded as the circulatory disturbance during the perinatal period. Also,neonatal asphyxia was the most important cause of the circulatory disturbance. But we experienced a case of multicystic encephalomalacia in a liveborn twin with a stillborn...
A Case of Early Onset Cerebellar Ataxia with Retained Tendon Reflexes
Jong Bum Lee, Hae Yong Lee, Jae Seung Yang, Baek Keun Lim
Clin Exp Pediatr. 1997;40(1):129-133.   Published online January 15, 1997
A Case of Acyclovir Induced Acute Tubular Necrosis
Mi Ya Park, Mee Kyung Namgoong, Hwang Min Kim, Baek Keun Lim, Sun Hee Jung
Clin Exp Pediatr. 1995;38(9):1283-1287.   Published online September 15, 1995
Acyclovir is generally regarded as a safe and highly effective antiviral agent in normal, as well as in immunocompromised hosts. Major renal complication was unusual. However, reversible renal dysfunction has been reported. The impairment of renal nephropathy resulting from crystal formation in the renal tubules or the collecting ducts. But we experienced a case of immunocompetent patient who developed severe...
Three Cases of Pneumoperitoneum in Ventilated Newborns
Chun Ok Yang, Ho Young Lee, Won Kju Choe, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1995;38(7):1006-1011.   Published online July 15, 1995
Pneumoperitoneum in the newborn is usually a surgical emergency resulting from gastroint-estinal perforation. However, pneumoperitoneum can occur secondary to a pulmonary air leak which progresses from the mediastinum to the retroperitoneum by way of perivascular spaces and then to the peritoneum following rupture. We have observed this phenomenon in three ventilated newborn. A brief review of the related literatures was...
A Case of Congenital Dyserythropoietic anemia Type IV
Hwa Young Jeon, Hwang Min Kim, Baek Keun Lim, Duk Woo Park, Myung Seo Kang, Young Kun Deung
Clin Exp Pediatr. 1995;38(5):702-706.   Published online May 15, 1995
Congenital dyserythropoietic anemia(CDA) is characterized by ineffective erythropoiesis an d increased numbers of multinucleated red cell precursors in the marrow. This syndrome has b een subdassified on the basis of morphologic and serologic differences in the red cell pecursors. There are some patients with congenital dyserythropoietic anemia who do not fit into the conventional classification of type I, II, or...
Original Article
Relationship of Echocardiographic, Shunt Flow, and Angiographic Size to the Operation Diameter of the Atrial Septal Defect
Dae Kwon Hong, Hae Yong Lee, Baek Keun Lim
Clin Exp Pediatr. 1995;38(2):232-239.   Published online February 15, 1995
This report is based on analysis of admissions to the department of pediatric at the Wonju Christian Hospital during the 3 3/4-year period from January 1989 to September 1993 with an Isolated ostium secundum ASD. Several methods of assessment of ASD size, namely, echographic, pulmonary-to-systemic flow ratio(Qp:Qs), and angiographic measures, were undertaken in a group of 37 patients, who were being...
Case Report
A case of Central Diabetes Insipidus Associated with Brachycephaly
Woo Sik Kang, Mee Kyung Namgoong, Jae Seung Yang, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1994;37(2):282-287.   Published online February 15, 1994
Brachyecphaly is a kind of craniosynostosis. Because of premature closure of the coronal suture, the skull is shorter in the anteroposterior diameter but is widened with a high vault and the occiput and borehead are flattened. Diabetes insipidus had been reported in oxycephaly. We have experienced a case of central diabetes insipidus associated with brachcephaly. A brief review of related literatures...
Original Article
Analysis on the Cause of Eosinophilia in Premature Infants
Woo Sik Kang, Suck Kyu Hur, Mee Kyung Namgoong, Hwang Min Kim, Baek Keun Lim
Clin Exp Pediatr. 1994;37(1):47-53.   Published online January 15, 1994
Eosinophilia is a common finding in premature babies during the neonatal period. Serial eosinophil counts were determined in 94 hospitalized, appropriately grown premature infants whose gestational ages ranged from 28 to 36 weeks. The incidence, sseverity and etiologic factors of eosinophila were retrospectively studied in premature infants, who were divided into three groups according to their gestational age. The results were...
Clinical Characteristics of Inborn and Outborn Infants Admitted to the NICU
Hyun Cheol Lee, Jin Young Choi, Hwang Min Kim, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1993;36(12):1647-1655.   Published online December 15, 1993
Regionalization of high-risk perinatal care has been advocated because intensive care of small and ill newborn infants lowers mortality and morbidity. This report is based on analysis of admissions to the Neonatal Intensive Care Unit (NICU) at the Wonju Christian Hospital during the 4-year period from January, 1988 to December, 1991. There were 786 inborn infants and 1155 outborn...
Clinical Observation of Aseptic Meningitis Associated with Mucocutaneous Lymph Node Syndrome
Jae Hee Han, Seon Jin Ji, Mee Kyung Namgoong, Hae Yong Lee, Jae Seung Yang, Baek Keun Lim
Clin Exp Pediatr. 1993;36(6):805-809.   Published online June 15, 1993
Clinical observation was carried out for 147 patients with mucocutaneous lymph node syndrome(MCLS) who were admitted to the Department of Pediatrics, Wonju Cristian Hospital during the period from June, 1983 to June, 1992. A spinal tap was performed on 114 of these patients and the following results were obtained. 1) The incidence of aspetic meningitis in patients with MCLS was 52.6%.(60...
Case Report
Three Cases of Purpura Fulminans
Sun Hee Suh, Hwang Min Kim, Jae Seung Yang, Baek Keun Lim
Clin Exp Pediatr. 1993;36(5):725-732.   Published online May 15, 1993
Purpura fulminans is one of rare consumptive coagulopathy in children. The most common prediasposing conditions of purpura fulminans are infectious disease like streptococcal infection and chickenpox. This disease is characterized by ecchymotic lesions that are usually distributed symmetrically on the lower extremities and buttocks. These ecchymotic lesions undergo necrosis, unless there is effective treatment. We experienced 3 cases of purpura fulminans...
Original Article
The Significance of Nucleated Red Blood Cell Counts in Various Conditions Associated with Acute or Chronic Perinatal Asphyxia
Suck Kyu Hur, Moon Sang Park, Mee Kyung Namgoong, Hwang Min Kim, Jae Seung Yang, Baek Keun Lim, Jong Soo Kim, Myung Seo Kang
Clin Exp Pediatr. 1992;35(11):1514-1519.   Published online November 15, 1992
This study was conducted to find out the significance of nucleated red blood cell (NRBC) in neonates, especially associated with acute or chronic perinatal asphyxia. So, we compared NRBC counts in various neonatal groups, such as normal newborn, small for gestational age (SGA), premature, acute perinatal asphyxia, & hyaline membrane disease (HMD). In the first day of life, we examined...
Case Report
A Case of Poststeroid Panniculitis
Moon Sang Park, Mee Kyung Nam, Hae Yong Lee, Baek Keun Lim, Jong Soo Kim, Sun Won Hong
Clin Exp Pediatr. 1992;35(3):406-410.   Published online March 15, 1992
Poststeroid panniculitis occuring after steroid treatment is an extremely rare entity. Multiple subcutaneous, firm, pruritic, tender nodules occur chiefly over the cheeks, arms, and trunk in young children following sudden discontinuation of large dose of steroids. We experiened a case of poststeroid panniculitis in a 2day-old female infant with complaints of multiple subcutaneous nodules on cheeks and neck...
Erratum
Effect of Intralipid infusion on the Metabolism
Baek Keun Lim
Clin Exp Pediatr. 1992;35(3):289-295.   Published online March 15, 1992
Original Article
The Comparision of Brain Computed Tomography and Isotope Cisternography in Communicating Hydrocephalus
Jong Chan Kim, Hwang Min Kim, Jae Seung Yang, Baek Keun Lim, Chul Hu, Soon Ki Hong, Young Hyuk Lee
Clin Exp Pediatr. 1992;35(1):9-16.   Published online January 15, 1992
Brain computed tomograpy is particularly accurate in defining cerebrospinal fluid (CSF) space because of the relatively great density difference between CSF and brain parenchyma. This noninvasive procedure has very quickly become definitive in the diagnosis of hydrocephalus. However, while the typical clinical and radiological picture of a hydrocephalic patient leaves no doubt as to the need for adequate surgical treatment....
A case of myelofibrosis with juvenile xanthogranuloma.
Jong Chan Kim, Hae Yong Lee, Hwang Min Kim, Baek Keun Lim, Jong Soo Kim, Young Hyuk Lee
Clin Exp Pediatr. 1991;34(6):869-876.   Published online June 30, 1991
Myelofibrrosis is characterized by anemia, leukoerythroblastosis, extramedullary hematopoiesis, hepatosplenomegaly, osteosclerosis and fibrosis of bone marrow. Idiopathc myelofibrosis is usually a disease of the adult and is rare in the pediatric age group. Juvenile xanthogranuloma is characterized by multiple papules on forehead and scalp. Lipid laden histiocytes and Touton giant cell are found in skin biopsy. We experienced a case of myelofibrosis with juvenile xanthogranuloma....
Two cases of ectopic sublingual thyroid with hypothyroidism to be appeared in fetal life.
Dong Sik Kim, Mee Kyung Namgoong, Hae Yong Lee, Hwang Min Kim, Baek Keun Lim
Clin Exp Pediatr. 1991;34(3):426-434.   Published online March 31, 1991
Infants & children with hypothyrodism usually manifest variable skeletal abnormality. These features are the delay in longitudinal bone growth, the delay in epiphyseal maturation (=delay in bone age), the disturbances in bone mineralization and charateristic multiple stippled epiphysis (cretenoid epiphyseal dysgenesis). But many pediatrician have only concerned about the delay in epiphyseal maturation. Epiphyseal dysgenesis can be used a marker to find out the begining...
A case of citrobacter freundii osteomyelitis.
Hyung Goo Cho, Dong Sig Kim, Hwang Min Kim, Jae Seung Yang, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1991;34(3):408-412.   Published online March 31, 1991
Citrobacter although once regarded as nonpathogenic, has been responsible for many well- documented pathologic conditions, especially in compromised hosts. These include urinary tract, pulmonary and bone infections, gastroenteritis, gangrenous ulcer with septicemia, meningitis, and brain abscess. Citrobacter organisms have a mosaic of 0, K and H antigens that are found in the Enterobacter- iaceae. Cross reactions with antisera of other members of the Enterobacteriaceae suggest...
The normal values of platelet count, mean platelet volume and platelet distribution width in the normal newborn, small for gestational age and premature neonates.
Eun Kyung Oh, Hae Yong Lee, Hwang Min Kim, Jae Seung Yang, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1991;34(3):340-347.   Published online March 31, 1991
The importance of establishing authentic normal platelet count, mean platelet volume and platelet distribution width in the newborn has been emphasized, but they have not been firmly established. We have presented values for platelet count, mean platelet volume and platelet distribution width in the venous blood of term, small for gestational age and premature neonates at postnatal day 1 and 7. The results were...
Three Cases of Transverse Myelopathy.
Hae Joung Joung, Hwang Min Kim, Jae Seung Yang, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1990;33(10):1418-1422.   Published online October 31, 1990
Transverse myelopathy is characterized by a sudden onset of motor weakness and sensory loss on the distribution under the affected spinal cord level. And slso, autonomic nerve functions may be disturbed at the same time. The etiology is still unknown. But it is thought that numerous conditions and diseases are associat- ed with it. We experienced 3 cases of transverse myelopathy preceded by Korean hemorrhagic...
A Case of Hypertrophic Cardiomyopathy in Identical Twin.
Wea Kyoung Shin, Hae Young Lee, Hwang Min Kim, Jae Seung Yang, Baek Keun Lim, Jone Soo Kim
Clin Exp Pediatr. 1990;33(10):1399-1405.   Published online October 31, 1990
Hypertrophic cardiomyopathy is a common genetically transmitted disorder characterized by asymmetric septal hypertrophy and systolic anterior motion of the mitral valve. We have recently experienced identical twin with the hypertrophic cardiomyopathy confirmed by M-mode and 2-D echocardiography. It is the first report of hypertrophic cardiomyopathy in identical twin in Korea. So presented this case with a review of referential literatures.
A Case of Esophageal Duplication.
Hyung Kuk Ham, Jeong Kyu Seoh, Jae Seung Yang, Baek Keun Lim, Jong Soo Kim, Hee Jae Joo
Clin Exp Pediatr. 1990;33(8):1134-1139.   Published online August 31, 1990
Esophageal duplication, a term used synonymously with enteric cyst, foregut cyst, gastroenteric cyst, enteric duplication, and etc, is a rare developmental anomaly which occures during differentia- tion of the larynx, trachea, and bronchi from the primitive foregut. They may cause dysphagia, regurgitation, pneumonia, hemoptysis, and occasionally produce alarming airway obstruction. We experienced a case with chief complaints of pale appearance and swallowing difficulty in...
Two cases of Glanzmann's thrombasthenia in brother.
Won Mo Yang, Hyung Kook Ham, Mee Kyung Namgoong, Baek Keun Lim, Hong Sup Yoon, Kab Joon Yoon
Clin Exp Pediatr. 1989;32(11):1574-1580.   Published online November 30, 1989
Glanzmann’s thrombasthenia is rare congenital bleeding disorder of autosomal recessive trait. We experienced two cases of Glanzmann’s thrombasthenia in brother. The mother and elder brother had no history of bleeding tendency. But 10 year-old and 7 year-old younger brothers had frequent epistaxis, gum bleeding and easy bruisability. On platelet aggregation test, mother and elder brother appeared normal responses, but the younger brothers appeared no responses...
A Case of Massive Thymic Hyperplasia.
Hye Kyung Bae, Jung Kyu Suh, Jae Seung Yang, Baek Keun Lim, Yeun Kee Kim, Chan Il Park
Clin Exp Pediatr. 1988;31(11):1516-1521.   Published online November 30, 1988
We have experienced a case of massive thymic hyperplasia in 2 months old female with about 1 month’s history of upper respiratory tract infection and inspiratory stridor. The chest X-ray and chest CAT scan examination revealed superior mediastinal huge mass and so surgical resection and pathologic examination were perfermed because of clinical suspicion of pathologic mass. The pathologic finding of mass showed massive thymic...