Varicella is usually considered to be a benign disease in healthy children; however, serious complications can occur such as necrotizing fasciitis and toxic shock syndrome. We describe a 38-month-old girl with necrotizing fasciitis and streptococcal toxic shock syndrome following varicella. She was previously healthy and vaccinated against varicella at 12 months of age. She had been diagnosed with varicella three... |
Renal size is an important indicator to determine adequate organ growth in children. The aim of this study was to estimate renal size with Technesium-99m dimercaptosuccinic acid (DMSA) scan and propose a simple formula for predicting renal length in normal Korean children. This study included 346 children (148 boys and 198 girls; age range, 1 month to 17 years) in whom... |
Somatic growth is an important indicator of health in children. Adequate organ growth is essential in growth and directly related to body growth. We consider renal length as a surrogate of organ growth in growing children. Measurement of weight, height, and many anthropometric indices, such as body surface area (BSA), body mass index (BMI), and Rohrer and Kaup indices, are... |
Microalbuminuria is defined as increased urinary albumin excretion (30-300 mg/day) or microalbumin/creatinine ratio (30-300 mg/g) in a spot urine sample. Although microalbuminuria is a predictor of clinical nephropathy and cardiomyopathy, few studies have investigated microalbuminuria in children with urinary tract infection (UTI). Therefore, we compared the spot urine microalbumin/creatinine ratio in pediatric UTI patients with that of control subjects. We investigated... |
Purpose : To evaluate the significance of clinical signs and laboratory findings as predictors of renal parenchymal lesions and vesicoureteral reflux (VUR) in childhood urinary tract infection (UTI). Methods : From July 2005 to July 2008, 180 patients admitted with a first febrile UTI at the Pediatric Department of Konkuk University Hospital were included in this study. The following were... |
Malaria caused by Plasmodium species is characterized by paroxysms of fever, chills, fatigue, anemia, and splenomegaly. Vivax malaria has lately re-emerged as an infectious disease and has exhibited high transmission rate in northern Gyeonggi-do province. We encountered a case of malaria in a child presenting with fever and thrombocytopenia who had recently made a school excursion to Pocheon-gun, Gyeonggi-do. The... |
Kikuchi-Fujimoto disease was initially described as a self-limiting histiocytic necrotizing lymphadenitis in Japan in 1972, and is predominantly observed in women under the age of 30 year and in Asian populations. The pathogenesis is still poorly understood but is thought to include infections, and autoimmune and neoplastic diseases. The most common clinical manifestations are fever and painless cervical lymphadenitis. Diagnosis... |
The Cerebro-oculo-facio-skeletal (COFS) syndrome is a rare autosomal recessive disorder characterized by multiple abnormalities that involve the brain, face, eyes, and extremities. COFS syndrome is regarded as a degenerative disorder of the brain and spinal cord caused by a mutation of the DNA repair genes. We report on an 8-month-old girl with COFS syndrome who exhibited growth and developmental delay,... |
Purpose : An outbreak of ESBL-producing Shigella sonnei enteritis was unprecedented not only in Korea but throughout the world in the past. We intended to devise a management guideline for ESBL-producing shigellosis based on analysis of clinical manifestations and response to therapy. Methods : We analyzed 103 patients who were admitted to the hospital with acute GI symptoms and were... |
Purpose : Rotavirus is a leading cause of severe gastroenteritis in infants and young children around the world. The aim of this study is to investigate the fat content in stools of patients with rotaviral enteritis compared to the stools of children who had no gastroenteritis. Methods : Seventy two patients who were admitted to Konkuk University Hospital, College of... |
Purpose : For the early diagnosis of Henoch-Schonlein purpura(HSP) presenting with acute abdominal pain preceding skin rash. Methods : The clinical, endoscopic and radiological records of 23 cases of HSP, presenting with gastrointestinal symptoms preceding skin rash were reviewed. Results : The intervals from the onset of abdominal pain to the development of the skin rash were one day to 30 days(median... |
Purpose : Steatorrhea tests have been developed using various methods. Acid steatocrit is a simple method to detect steatorrhea and has very high sensitivity and specificity. This present study was designed to establish the normal values of acid steatocrit in Korean infants and to find the difference according to the various feeding methods. Methods : Acid steatocrit tests were conducted on... |
Duplications of the stomach account for only 3.8% of gastrointestinal duplication, mainly discovered during first year of life. Etiopathogenesis is unknown. The most widely accepted theory is recannalization with fusion of longitudinal epithelial fold. The most frequent presented symptoms and signs include gastric outlet obstruction with vomiting, and palpable mass in the epigatric area. An upper gatrointestinal series usually reveals evidence of extrinsic mass... |
The aim of this study was to determine the applicability of reverse transcription and polymerase chain reaction(RT/PCR) for routine diagnostic use and for the detection of enteroviral mentigitis, Primers were selected in the highly conserved part of the 5'-non-coding region of the enteroviral genome. Enteroviral RNA was detected by the RT/PCR in routinely collected cerebrospinal fluids(CSF) of patients with aseptic... |
Coxiella burnetii(C. burneii) was first recognzed as the agent of Q fever in 1937. Q fever is an acute self-limited febrile illness. However, it manifests with several clinical symptoms depending upon the organs that are involved. The association of C. burnetii with human neoplasia has been rarely reported. We prospectively studied the 55 patients with fever of unknown origin, pneumonia, hepatos-plenomegaly,... |
A short umbilical cord is defined as 35 cm or less, whereas a long cord is 80 cm or more. Short umbilical cords have been associated with a delay in the second stage of labor, irregular fetal heart tones, placental abruption, rupture of the umbilical cord, inversion of the uterus, birth asphyxia, umbilical hernia and long umbilical cord have been associated more frequently... |
Almost of all patients with neurofibromatosis type I show caf6-au-lait macules on their skin. These macules are thought to be early sign of neurofibromatosis in childhood. We experienced a case of neurofibromatosis type I in a 10-year-old-boy who did not have caf6-au-lait macules, but progressive psychomotor retardation, short attention span, hyperactivity and megalencephaly. The brain C-T findings showed diffuse cerebromalacia and ventriculomegaly. We confirmed the... |
The mega cistema magna is a congenital developmental malformation. The size of the cistema magna and the criterion of the mega cistema is still debatable. A clinical study had been performed on 12 children with mega cistema magna diagnosed by computed tomography scan from January 1980 to December 1990. The results are summarized as follows: 1) Among 4900 consecutive unselected computed tomography scans, twelve cases with... |
Subcutaneous fat necrosis of the newborn is an uncommon inflammatory disorder of adipose tissue, which is characterzed by multiple erythematous subcutaneous nodular swellings appearing in the first week to a month of life with occasional diffuse calcification. The precipitating factors presumably concerned in the disease are asphyxia, birth trauma, irritation and cold exposure. We observed a case of subcutaneous fat... |
Hepatitis has rarely been recognized as a complication of acute measles infection. Recently, a 10 month old girl is reported in whom abnormal liver function was a prominent clinical feature during acute measles infection. Hepatitis may be a clinical manifestation of acute measles infection of infant. |
The following results were obtained through the clinical review of 24 cases with the intes- tinal tuberculosis under the age of 15 years which were treated at Seoul National University hospital and Kangnam General Hospital Public Corporation during the period of 6 years from January, 1977 to December, 1982. 1) The peak incidence was noted in the group aged 12 〜 15 years. The ratio... |
We have experienced a case of precocious psevdopuberty due to granulosa cell tumor in a female infant, aged 11 months. She had whitish vaginal discharge and two episcdes of vaginal bleedirg one month apart. The breasts were markedly enlarged for her age but pubic ard axillary hair were not noticed. Recto abdominal examination revealed a firm, adult wrist sized, globular mass,... |
Medullary sponge kidney is uncommon disease and rare in children. It is characterized by localized dilatation of collecting ducts in renal pyramids. The diagnosis of medullary sponge ki-dney depends mainly upon intravenous and retrograde pyelography. This paper presented a case of medullary sponge kidney found in a 9-year-old boy during the study about enuresis, and a brief review of literature... |
A clinical study was made on 58 cases of neonatal meningitis occuring under the age of 1 month in the department of Pediatrics at Severance Hospital, yonsei University College of Medicine, from Jan. 1, 1965 to Dec. 31, 1978. 1. The sex ratio of male and female was approximately 1.8:1. 2. Neonatal predisposing factors significantly associated with meningitis were omphalitis(14... |
Moyamoya disease is characterised by stenosis or occlusion in the distal portions of the internal carotid artery. There is the associated finding of a fine network of abnormal vessels ('moyamoya' vessels, that is 'puff of smoke' like appearance) in the region of the basal ganglia. We experienced two cases of moyamoya disease which was confirmed by carotid angiogram. Case 1... |
Serum immunoglobulin concenatrations were measured in 156 patients with various types of glomerulonephritis such as acute poststreptococcal glomerulonephritis, minimal lesion nephrotic syndrome and Henoch-Sch?lein purpura nephritis. 1) Serum IgG level was above normal mean in acute poststreptococcal glomerulonephritis, and normal range in Henoch-Scholein purpura nephritis. Serum IgG concentrations were significantly reduced in minimal lesion nephrotic syndrome. 2) Serum IgA concentrations... |
This paper presents a case of^recurrent Guillain-Barre syndrome in a 13 year-old boy. Recu-rrent rate is variable but almost all of the authors expressed it was very rare and some of them recurred more than two times and and its interval also variable from few months to 17 years. In our case, he developed a typical ascending, symmetric motor paralysis... |
Hepatorenal syndrome is generally urged, at least until specific interrelationships between the two organs are confirmed by experimental and clinical data. Case I was a 11 year old boy, who had been suffered from acute fulminant viral hepatitis, which had developed acute hepatic necrosis associated with acute renal failure. Cass H was a 10 year old girl, who was performed corrective... |
Two cases in which postoperative hepatic necrosis followed by halothane(fulthane) anesthesia are presented. Case 1 was 3 dar-old neonate who was performed corrective surgery for jejunal atresia under the halothane anesthesia. He was placed with hyperalimentation just after operation, and was relatively well. He died on postoperative 11 days. Necropsy matrial was obtained from liver. Histologic finding of liver disclosed... |
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