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Adrenocortical carcinoma is a rare disease in childhood. Most of these carcinomas are functional, produc-
ing endocrine abnormalities such as Cushing syndrome, virilization, precocious puberty, hyperaldosteronism
or feminization.
We experienced a case of adrenocortical carcinoma in a 12 month old male infant who exhibited features
of Cushing syndrome, Virilization, precocious puberty and hyperaldosteronism, which were due to functional
adrenocortical carcinoma. Microscopic examination revealed cellular pleomorphism... |