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Original Article
Protective Effect of Breast Feeding for Infection
Jin Kyung Jung, In Nam Kang, Dong Ju Sin, Doo Bong Lee
Clin Exp Pediatr. 1994;37(7):906-912.   Published online July 15, 1994
A Comparative study was retrospectively performed with 374 infants in order to find protective effect of breast feeding for infection. This study shows that breast feeding protect infant against gastrointestinal and respiratory infcttion. Breast feeding offers advantage by reducting gastraintestinal and respiratory infection when they should maintain breast feeding for at least three months. 1) First year morbidity increased with extent of artificial...
Occult Mediastinal Ganglioneuroblastoma Presenting with Myoclonic Encephalopathy as Paraneoplastic Syndrome
Hahng Lee, Dong Ki Han, Jae Won Oh, In Joon Seol, Eun Kyung Hong, Seok Chol Jeon
Clin Exp Pediatr. 1994;37(5):695-700.   Published online May 15, 1994
Ganglioneruroblastoma and neuroblastoma are among commonest types of childhood malignancy and a number of unique paraneoplastic syndromes have been associated with both localized and disseminated neuroblastoma. The coincidence of neuroblastoma and myoclonic encephalopathy or other paraneoplastic syndromes occurs relatively rare, and therefore, failure to recognize this association could result in delays in both diagnosis and treatment, and the result...
The Effect of Cranial Irradiation on Growth of Children with Lymphatic Origin Tumors
Jin Seoup Jung, Yon Sook Rho, Sang Woo Kim
Clin Exp Pediatr. 1994;37(5):666-671.   Published online May 15, 1994
A retrospective study was conducted to investigate the effects of CNS prophylaxis with 1,800cGy cranial irradiation on standing height growth of children with acute lymphoblastic leukemia(ALL). Seventeen longterm survivors (DFS over 5 years) of ALL and Non-Hodgkins Lymphoma who had been admitted at pediatric department of Inje University Seoul Paik Hospital from January 1982 to September 1988 were studied. The long term...
Primary Cutaneous Aspergillosis in Leukemic Children
Jin Young Park, Mee Ran Kim, Hee Young Shin, Hoan Jong Lee, Hyo Seop Ahn, Je Guen Chi
Clin Exp Pediatr. 1994;37(4):520-526.   Published online April 15, 1994
Primary cutaneous aspergillosis is rare. In this report we describe primary skin infection by Aspergillus in 9 children with leukemia. The skin lesion was characterized clinically by erythematous macule and papule associated with pain and itching, followed by a rapid progression to ulcer and central black eschars with raised erythematous border at the site of venipuncture, insertion of intravenous cannula,...
Mechanism of Impaired Growth Hormone Response in Children with Simple Obesity
Moon Sung Park, Mi Jung Park, Ho Seong Kim, Duk Hi Kim
Clin Exp Pediatr. 1994;37(4):457-463.   Published online April 15, 1994
Obesity is associated with an impairment of the hormone secretion elicited by all stimuli known to date, but the basic mechanism of this alteration is unknown, To determine whether obesity is associated with a chronic state of tonic somatostatin, several tests with growth hormone stimuli such as GHRH (1㎍/kg), clonidine (150㎍/m2) and Resular insulin (0.1U/kg, subcutaneously), to obese subjects and...
Case Report
Two Case of Psedohypoaldosteronism Type 1
Ji Eun Lee, Jung Wan Seo, Seung Joo Lee
Clin Exp Pediatr. 1994;37(1):122-128.   Published online January 15, 1994
Pseudohypoaldosteronism type 1 is a genetic renal tubular disease of salt wasting, presenting in young infants. Tubular unresponsiveness to elevated endogenous an exogenou aldosterone is the suggested pathogenetic mechanism. Oral sodium chloride supplementation relieve the clinical symptoms and electrolyte distrubances. We experienced 2 cases of PHA type 1 in 38-day and 450day old male infants who were presented with failure to...
Original Article
Diagnostic Significance of Red Cell Indices in Non-anemic Iron Deficiency and Iron Deficiency Anemia: Reevaluation with ROC Curve
Hwang Min Kim, Won Kyu Choi, Jae Seung Yang, Jong Soo Kim
Clin Exp Pediatr. 1994;37(1):33-39.   Published online January 15, 1994
To validate the diagnostic significance of red cell indices in non-anemic iron deficiency and iron deficiency anemia, complete blood count, serum iron, total iron binding capacity, and serum ferritin were measured in 208 middle school girls between 13 and 15 years age. We used Reciever Operating Characteristic (ROC) curve to compare the diagnostic significances of various red cell indices (MCV,...
Case Report
A Case of Sacrococcygeal Teratoma with Spina Bifida Cystica in Newborn
Tae Woo Kim, Sung Ki Park, Young Soo Baik, Hee Sin Ko, Dong Uk Kim, Woo Taek Kim, Woong Hm Kim, Chang Yeun Lee, Young Bae Lee
Clin Exp Pediatr. 1993;36(12):1747-1751.   Published online December 15, 1993
Sacrococcygeal teratoma is a rare tumor, it occurs once in every 40,000 live births. Most of the reported cases appear in female infant (M:F=1:4). They deserve clinical attention because they are potenially malignant and are curable if diagnosed and treated early. The patients may have associated congenital anomalies. This patient has spina bifida cystica in lower sacrum. Brief review of related literature is included...
Original Article
Chronic Idiopathic Intestinal pseudo-obstrucion Syndrome in Childhood
Jae Geon Sim, Jeong Kee Seo, Kui Won Park, Je Geun Chi
Clin Exp Pediatr. 1993;36(11):1583-1595.   Published online November 15, 1993
Chronic idiopathic intestinal pseudo-obstruction syndrome is a clinical condition induced by an impaired function of intestinal motility. Although its clinical symptoms are those of intestinal obstruction, mechanical obstruction of the intestine cannot be found by vigorous studies, even by operative exploration. We have experienced nine cases of chronic idiopathic intestinal pseudo-obstruction syndrome. It will help in diagnosis and treatment of the...
A Clinical Study of Histiocytosis Syndrome
Hye Yong Lee, Chul Hee Chung, Won Suk Suh, Sang Mann Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1993;36(10):1417-1425.   Published online October 15, 1993
We made a clinical study on 10 cases of histiocytosis syndrome who had been admitted to the pediatric department of Soon Chun Hyang University Hospital from Jan 1982 to Dec. 1991. The results were obtained as follows 1) The sex incidence revealed male predominance with the ratio 4:1. 2) Among 10 cases, 4 cases were classified as eosinophilic granuloma, 1 case as Letterer-Siwe...
Statistical Observation on Neonate
Dong Il Park, Chel Gi Kim, Jin Bok Hwang, Chang Ho Han, Hye Le Chung, Young Dae Kwon
Clin Exp Pediatr. 1993;36(8):1080-1093.   Published online August 15, 1993
A statistical obsevation was performed on 13,317 cases of neonates who had been delivered at Taegu Catholic Hospital during the past 3 years from Jan. 1 st 1988 to Dec. 31 st 1990. The results obtained were as follows: 1) Among 13,317 neonates, the male was 7,234 and the femlae 6,083, with the sex ratio of male to female being 1.19:1 2) Percentage...
Treatment of Aplastic Anemia
Nak Gyun Chung, Kyu Jin Bhang, Woo Gun Choi, Hack Ki Kim, Kyong Su Lee, Man Kyu Yang
Clin Exp Pediatr. 1993;36(8):1059-1066.   Published online August 15, 1993
We performed this study to evaluate the therapeutic responses of bone marrow transplantation and immunosuppressive therapy for aplastic anemia in 103 cases(68 severe and 35 moderate). Among them, 15 cases with severe aplastic anemia having HLA-identical sibling donor underwent bone marrow transplantation, and cases (53 severe and 35 moderate cases) without available HLA-identical sibling donor had received immunosuppressive therapy using...
Plasma Norepinephrine Levels in Infants and Children with Congestive Heart Failure
Sang Woog Lee, Myung Sung Kim, Sang Lak Lee, Tae Chan Kwon, Chin Moo Kang
Clin Exp Pediatr. 1993;36(7):982-986.   Published online July 15, 1993
To characterize the sympathetic nervous system response to congestive heart failure in infants and children, plasma norepinephrine levels were measured in 29 patients aged 4 months to 15 years undergoing routine cardiac catheterization at Dong San Hospital, Keimyung University during the period of 4 months from November 1990 to February 1991. Plasma norepinephrine levels were significantly higher in patients with heart...
A Clinical Review of Congenital Gastrointestinal Anomalies
Dong Hak Shin, Woo Hyun Park, Chul Young Bae
Clin Exp Pediatr. 1993;36(7):944-950.   Published online July 15, 1993
A clinical review was done on 343 infants and children diagnosed and operated at the Department of Pediatric Surgery in Keimyung University, Dong San Medical Center for congenital gastrointestinal anomalies from January, 1988 to December, 1991. The results are summarized as follows; 1) The most prevalent age group of congenital gastrointestinal anomaly was within first week after birth, and infants within 3months...
Bilateral Torsion of the Testes in a Newborn Infant
Eun Sook Kim, Hang Mi Kim, Song Kwang Jung
Clin Exp Pediatr. 1993;36(5):721-724.   Published online May 15, 1993
We report one case of bilateral testicular torsion. A 4000 gm male infant, born by cesarean section due to induction failure at 42 weeks gestation, was hospitalized at 9 days of age secondary to bilateral testicular mass. Physical examination revealed an healthy baby with enlarged, firm, nontender mass on both sides of the scrotum. Transillumination of the mass shwed no transmission...
A Clinical Study of Testicular Relapse in Childhood Acute Lymphocytic Leukemia
Hye Ok Roh, Chuhl Joo Lyu, Seung Hwan Oh, Chang Hyun Yang, Kir Young Kim, Byung Soo Kim
Clin Exp Pediatr. 1993;36(5):680-686.   Published online May 15, 1993
From January 1984 to June 1991, we studied testicular relapsed patients among 105 cases of acute lymphocytic leukemia in children who were admitted to the Department of Pediatrics and Yonse Cancer Center, Yonsei University Severance Hospital. The results were as follows: 1) 15 out of 105(14.4%) cases of acute lymphocytic leukemia were diagnosed as testicular relapse. According to the prevalence by the...
The Statistical Observations for Pediatric Inpatients (1971-1990)
Hwa Ja Kim, Yong Min Jung, Sang Kyu Park, Ho Jin Park, Mi Ja Shin, Suk Chul Kang
Clin Exp Pediatr. 1993;36(5):615-625.   Published online May 15, 1993
We observed the patients admitted to the department of pediatrics Seoul Red Cross Hospital during the past twenty years from Jan. 1971 to Dec. 1990 The results were as follows: 1) The total number of pediatric inpatients during 20 years was 15,800, of which 9,683 were male, 6,117 were female and male to female ratio was 1.58:1 2) On age distribution, neonates and...
A Clinical Study of Myelodysplastic Syndrome in Children
Seong Hoon Hah, Hyo Seop Ahn
Clin Exp Pediatr. 1993;36(4):556-567.   Published online April 15, 1993
Myelodysplastic syndrome is a heterogeneous disease complex which is basically a clonal disorder and has characteristics of cytopenia of one or more cell series in peripheral blood and of dyspoiesis of precurosirs in bone marrow. Since the nature of this disease in childhooh is very different from that in adults, retrospective clinical study was performed with 17 confirmed patients who...
Case Report
A Case of Cavernous Lymphangioma in Mediastinum
Jin Kee Jung, Sang Du Lee, Kee Yong Park, Dock Yong Chung, Mi Sun Lee, Jong Gun Kim
Clin Exp Pediatr. 1993;36(3):417-422.   Published online March 15, 1993
Cavernous lymphangioma in mediastinum is a rare congenital malformation of lymphatic system and is caused by lack of adequate drainage from the sequestrated lymphatic vessels to the venous system due to insufficiency or atresia of the efferent lymphatic channels The authors experienced 10 month-old male patient with cavernous lymphangioma in mediastinum documented by chest CT and open biopsy. The review of the...
Original Article
Foreign Body in the Upper Gastrointestinal Tract in Infants and Children
Sang Heui Song, Ki Sup Chung
Clin Exp Pediatr. 1993;36(1):17-24.   Published online January 15, 1993
The accidental swallowing of foreign bodies by infants and children is a common problem. The proper methods of therapy must be carefully selected according to the age of the patient, the type of foreign body, the location of impaction, the duration of ingestion, and the available medical resoruces and skills. This report reviews 41 cases of ingested foreign bodies in...
Acute Megakaryoblastic Leukemia in Children
Hong Hoe Koo, Sang Kyu Park, Eun Sil Dong, Hye Jung Park, Hee Young Shin, Hyo Seop Ahn
Clin Exp Pediatr. 1993;36(1):9-16.   Published online January 15, 1993
We analyzed the clinical and laboratory features of ten children with acute megakaryoblastic leukemia (M7) and compared the findings with those reported in the literature. The diagnosis was supported by ultrastructural examination of platelet peroxidase or immunophenotyping for glycoprotein Iib/IIIa. Of the ten children, five were girls and five were boys. The median age at diagnosis was 13 months. Two...
Case Report
A Case of Intestinal Lymphangiectasia
Yae Kyung Suh, Kyung Hee Park, Chul Ho Jang, Bum Soo Park, Jeong Kee Seo, Sung Hae Park, Je Geun Chi, Kyung Mo Yeon, Kwi Won Park
Clin Exp Pediatr. 1992;35(12):1737-1743.   Published online December 15, 1992
Intestinal lymphangiectasia is a primary or secondary disorder of the gastrointestinal tract, which is associated with lymphatic dysfuction and protein-losing enteropathy. It's clinical manifestations vary widely, but the main symptoms are abdominal distention, edema, abdominal pain and growth failure. We described a 15-yr-old boy, who suffered from above symptoms since third year of his age and diagnosed by duodenal endoscopy which...
Original Article
Clinical Study and Availability of Ultrasonography in Hemorrhagic Cystitis
Jin Park, Chi Hyung Park, Chong Woo Bae, Sung Ho Cha, Byoung Soo Cho, Chang Il Ahn, Young Tae Ko, Sun Wha Lee
Clin Exp Pediatr. 1992;35(12):1722-1727.   Published online December 15, 1992
Acute hemorrhagic cystitis characterized by gross hematuria and symptoms of bladder irritation occurs in children as a self-limited disease that must be differentiated from serious renal disease. We analyzed 22 cases of hemorrhagic cystitis which were managed in the Dept. of pediatrics, Kyung Hee university hospital and present the availability of bladder sonography for diagnosis of hemorrhagic cystitis and for follow-up. The...
Septicemia in Children with Neoplastic Disease
Bo Young Yun, Hoan Jong Lee
Clin Exp Pediatr. 1992;35(11):1481-1492.   Published online November 15, 1992
This study reviewed 66 episodes of septicemia occurring in 56 children with neoplastic disease at Seoul National University Children뭩 hospital over 31 month period. The most frequent organisms causing 45 episodes in neutropenic patient were Escherichia coli (28%), Klebsiella species (18%), Pseudomonas species (9%), polymicrobic (9%,), and Staphylococcus aureus (7%). The overal mortality was 13% (5/39). The most frequent organisms...
Case Report
A Case of Chronic Intestinal Pseudo-obstruction Syndrome
Hye Won Park, Chul Ho Chang, Bum Soo Park, Jeong Kee Seo, Sung Hye Park, Je Geun Chi, Kyung Mo Yeon, Kui Won Park
Clin Exp Pediatr. 1992;35(10):1427-1434.   Published online October 15, 1992
Chronic intestinal pseudo-obstruction is a clinical condition in which impaired intestinal propulsion causes recurrent symptoms of bowel obstruction in the absence of mechanical occlusion. In this paper a female neonate was presented with vomiting and abdominal distension in the first few days of life but passed normal meconium. Barium enema showed a microcolon and an abnormaly sited cecum. Malrotation of bowel...
A Case of Intestinal Necrosis Associated with Henoch-Schönlein Purpura
Soo Jung Lee, Young Yoo Kim, Sung Soo Whang, Kyung Yil Lee, Won Ik Lee, Jeong Soo Kim, Chang Joon Ahn, Mi Kyung Jee
Clin Exp Pediatr. 1992;35(9):1291-1297.   Published online September 15, 1992
Gastrointestinal symptoms of Henoch-Schönlein commonly present abdominal pain, nausea, nomitting, melena and hematemesis and resolve mostly without any complications. Some times life threatening gastrointestinal manifestations such as massive hemorrhage, intussusception, intestinal necrosis and perforation may develop We report a case of the Henoch-Schönlein purpura with intestinal lesion in 11 year female patient who presented with colicky abdominal pain and bloody stool...
Original Article
A Clinical Study of Primay Gastrointestinal Lymphoma in Childhood
Hye Jung Joo, Chuhl-Joo Lyu, Byung Soo Kim, Euy Ho Hwang, Chang Ok Suh, Woo Ick Yang, Woo Hee Chung
Clin Exp Pediatr. 1992;35(9):1210-1219.   Published online September 15, 1992
The 18 cases of primary gastrointestinal lymphoma patients admitted to the Department of Pediatrics and Yonsei Cancer Center, College of Medicine, Yonsei University, during 15 years from January, 1975 to December, 1989 were reviewed on the bases of clinical characteristics, treatment, and survival rates. The results were summarized as follows; 1) The age of patients ranged from 3 years to 14 years,...
Case Report
Four Cases of Massive Infiltrating Congenital Cystic Hygroma Managed by Bleomycin Sclerosing Therapy
Hyun Kwack, Dong Wook Kim, Kyung Woon No, Jun Heo, Sun Young Kim, Young Pyo Jang, Jung-Hwan Choi, Chong Ku Yun, Seong En Jung, Gui Won Park, Woo Gi Kim, In Won Kim, Kyung Mo Yeon
Clin Exp Pediatr. 1992;35(8):1148-1156.   Published online August 15, 1992
Cystic hygroma is a true, benign, congenital multi-cystic tumor. It is thought to be arised from failure of the lymphatic system to communicate with the venous system. Frequently it occurs at birth, and it is found most commonly in the neck as painless and fluctuant mass. For many years, surgical excision has been considered as the treatment of choice. However, excision...
Original Article
Acquired Renal Cystic Disease in Childhood Chronic Renal Failure
Tae Sun Ha, Seong Hoon Ha, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Woo Sun Kim, Kim In One
Clin Exp Pediatr. 1992;35(8):1044-1050.   Published online August 15, 1992
The authors evaluated 19 childrenwith chronic renal failure patients diagnosed and followed up at the Department of Pediatrics, Seoul National University Hospital for the detection of acquired renal cystic disease (ARCD) with two radiologists by the means of ultrasonography. The results were as follows: 1) Of the 19 patients, male to femals ratio was 14:5 and of them, hemodialysis and peritoneal dialysis...
Statistical Observation for the Pediatric Patients in ICU
Ki Hun Eum, Chang Ho Hong, Young Mo Sohn, Chul Lee, Pyung Kil Kim
Clin Exp Pediatr. 1992;35(6):762-768.   Published online June 15, 1992
A statistical study was performed on 221 ICU cared pediatric patients who were admitted to the department of pediatrics, Yonsei university college of medicine, Seoul, Korea from Apr. 1983 to Mar. 1991. The results were as follows : 1) Total number of subject were 221, it was 7.5% of total ICU patients and 1.3% fo total admitted pediatric patients. The male to...
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