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Original Article
Changes of neurodevelopmental outcomes and risk factors of very low birth weight infants below 1,500 g, in the last 10 years
Se Kyu Lee, Ji Hyun Lee, Sang Geel Lee
Clin Exp Pediatr. 2006;49(10):1050-1055.   Published online October 15, 2006
Purpose : As a result of advances in neonatal intensive care and perinatal care, neurodevelopmental outcomes of very low birth weight infant(VLBWIS) is expected to lead to improvement. The aim of this study was to report neurodevelopmental outcomes and risk factors of neurologic impairment of very low birth weight infants during the past 10 years. Method : We performed a retrospective...
Comparison of total parenteral nutrition-associated cholestasis according to amino acid mixtures in very low birth weight infants
Jin-Sung Choi, Yun-Jin Bae, Young Ah Lee
Clin Exp Pediatr. 2006;49(9):972-976.   Published online September 15, 2006
Purpose : The purpose of this study was to evaluate the effect of amino acid mixtures on incidence and severity of total parenteral nutrition associated-cholestasis(PNAC) in very low birth weight infants. Methods : Retrospective review of 63 very low birth weight infants(birth weight ≤1,500 g) who received total parenteral nutrition(TPN) in our neonatal intensive care unit from January 2000 to...
Immune responses of hepatitis B vaccination among very low birth weight infant
Young-Deuk Kim, Myung-Ki Han, Ai-Rhan E. Kim, Ki-Soo Kim, Soo-Young Pi
Clin Exp Pediatr. 2006;49(8):857-863.   Published online August 15, 2006
Purpose : To evaluate the immunogenicity of hepatitis B vaccine among very low birth weight infants(VLBWI) who were vaccinated at 0, 1, 6 months of chronological age and to determine the factors associated with antibody formations. Methods : A total of 243 VLBWI admitted to Seoul and Gangneung Asan Medical Center neonatal intensive care units from 1997 to 2004 were...
Catch-up growth and development of very low birth weight infants
Tae Ho Ma, Kyung Ah Kim, Sun Young Ko, Yeon Kyung Lee, Son Moon Shin
Clin Exp Pediatr. 2006;49(1):29-33.   Published online January 15, 2006
Purpose : The aim of this study was to analyze the results and contributing factors of catch-up growth in very low birth weight infants(VLBWI) at the corrected age of 2 years. In addition, we looked for a relationship between the catch-up growth and the development by the bayley scales of infant development II(BSID II). Methods : A retrospective analysis by...
Clinical Use and Complications of Percutaneous Central Venous Catheterization in Very Low Birth Weight Infants
Hyang Kim, Sun Hui Kim, Hyung Suck Byun, Young Youn Choi
Clin Exp Pediatr. 2005;48(9):953-959.   Published online September 15, 2005
Purpose : The administration of total parenteral nutrition(TPN) has become a standard procedure in the management of nutritionally deprived and critically low birth weight neonates. Sepsis remains the most frequent serious complication during TPN, resulting in increased morbidity, mortality and health care costs. This study was performed to evaluate the clinical efficacy and complications of percutaneous central venous catheterization(PCVC) in...
Survival Rate in Very Low Birth Weight Infants
Jae Ju Cho, Soon Bum Lee, Woo Sung Park, Young Pyo Chang
Clin Exp Pediatr. 2004;47(5):505-509.   Published online May 15, 2004
Purpose : We observed changes in the outcome of very low birth weight infants(VLBWI) admitted to the neonatal intensive care unit(NICU) of Dankook University Hospital(DKUH) in the last six years. Methods : The distribution of birth weight and gestational age, survival rate, neonatal complications, and causes of death for 228 VLBWI who had been admitted to DKUH from 1st January...
Risk Factors of Nephrocalcinosis in Very Low Birth Weight(VLBW) Infants
Gyu Hong Shim, Jin A Lee, Yun Jung Shin, Ee Kyung Kim, June Dong Park, Beyong Il Kim, Jung Hwan Choi
Clin Exp Pediatr. 2004;47(3):275-281.   Published online March 15, 2004
Purpose : Nephrocalcinosis in very low birth weight(VLBW) infants were known to be caused by a longer duration of furosemide use. However, etiologies, pathogenesis and risk factors remain unclear. Therefore, we examined the incidence and risk factors of nephrocalcinosis in VLBW infants retrospectively. Methods : Inborn babies of birth weights less than 1,500 gm were examined retrospectively. Data were reviewed on...
Changes in Incidence, Survival Rate and Morbidity of Very Low Birth Weight Infants
Young Ok Kim, Sun Hui Kim, Chang Yee Cho, Young Youn Choi, Jin Hwa Kook, Tae Ju Hwang
Clin Exp Pediatr. 2003;46(8):769-776.   Published online August 15, 2003
Purpose : The survival rate of very low birth weight infants(VLBWI) has improved by virtue of specialized neonatal care. This study was performed to analyze the changes in incidence, survival rate and morbidity of VLBWI who admitted to Chonnam National University Hospital from 1996 to 2001. Methods : We enrolled 565 VLBWI, and compared the incidence and the survival rate according...
Changes in the Outcomes of Very Low Birth Weight Infants
Shung Shin Kim, Moon Hee Kim, Jae Won Shin, Sun Young Ko, Eun Kyung Lee, Yun Sil Chang, I Seok Kang, Won Soon Park, Mun Hyang Lee, Sang Il Lee, Heung Jae Lee
Clin Exp Pediatr. 2002;45(7):828-835.   Published online July 15, 2002
Purpose : The outcomes of infants weighing less than 1,500 gm(very low birth weight infant : VLBWI) reflect recent progress in neonatal intensive care. In this study, we analyzed changes over time in survival rate and morbidity of VLBWIs during the past seven years. Methods : A retrospective review of medical records was analyzed for VLBWIs admitted to the neonatal intensive...
Influence of Phototherapy on Incidence of Patent Ductus Arteriosus in Very Low Birth W eight Infants
Hee Seok Kim, Ee Kyung Kim, Yun Kyoung Lee, Hee Eun Lee, Chan Hwu Park, Kyung Ran Park, Jun Dong Park, Beyong Il Kim, Woong Heum Kim, Jung-Hwan Choi, Yong Su Yun, Chong Ku Yun, Jeong Mi Lee
Clin Exp Pediatr. 1997;40(10):1410-1418.   Published online October 15, 1997
Purpose : Patent ductus arteriosus(PDA) is a common disease in very low birth weight infants(VLBWI). Hemodynamically significant PDA increases the morbidity and mortality of premature infants. Based on experimental model, light inhibits the constriction of immature piglet' s ductal rings. No specific mechanism adequately explains the effect of light on the relaxation of PDA. Several hypotheses, including activation of photosensitive metabolites, alterations in receptors, or...
Impact of Perinatal Risk Factors on Mental or Psychomotor Developmental Outcome of Very Low Birth W eight Infants
Eun Kyung Jin, Jong Uk Kim, Do Whan Kil, Oh Kyung Lee
Clin Exp Pediatr. 1997;40(9):1202-1209.   Published online September 15, 1997
Purpose : To determine which perinatal risk factors influence neurodevelopmental outcome, we try to investigate which perinatal risk factors are correlated with Baley mental or psychomotor developmental index using BSID-Ⅱ test(Baley Scales of Infant Development, Ⅱ) in long term follow up of very low birth weight who received neonatal intensive care. Methods : This study was performed on 56 very low birth weight infants with...
Growth and Neurodevelopmental Outcome on Very Low Birth Weight Infants During 2 Years
Eun Suk Kim, Jong Uk Kim, Oh Kyung Lee, Wan Soeb Kim
Clin Exp Pediatr. 1996;39(5):641-651.   Published online May 15, 1996
Purpose : By rapid development of neonatal intensive care from 1960, we are able to expect the long survival of the very low birth weight infants. But, there were high risk of poor growth, neurodevelopmental delay, deafness, and blindness in very low birth weight infants. So, it is important to follow-up after discharge. We try to compare normal term infants with...
Effect of Intravenous Immunoglobulin(IVIG) on Renal Function in Very Low Birth Weight Infants
Hwa Young Jang, Haeng Mi Kim
Clin Exp Pediatr. 1996;39(4):475-481.   Published online April 15, 1996
Purpose : This study was conducted to evaluate the effect of IVIG infusion on renal function in VLBW infants. IVIG has been proved quite safe in neonates given prophylactic and therapeutic doses. But nephrotoxicity is not recognized as adverse in IVIG therapy, only several previous adult cases have been noted. Methods : For a total of ten VLBW infants who had...
Neurosonographic Abnormality; Periventricular echodensities and Intraventricular Hemorrhage: Usefulness in Predicting Neurodevelopmental Outcome in Very-Low-Birth-Weight, Preterm Infants
Dae Young Jang, Keun Wook Lee, Young Taek Jang, Oh Kyung Lee, Jin Ok Choi, Yeon Hi Kim
Clin Exp Pediatr. 1994;37(10):1376-1385.   Published online October 15, 1994
Serial neurosonographic examinations are routinely performed at frequent intervals during nursery couse of all preterm infants of very low-birth-weight who are admitted to the intensive care nursery of Presbyterian Medical Center from November 1,1900 to July 30, 1992. After discharge, the following survivors who had received periodic, serial scanning by means of cranial ultrasonography were longitudinally observed in an interdisciplinary neurodevelopmental...
Clinical Study on Very Low Birth Weight Infants
Sha Young Choi, Dae Young Jang, Oh Kyung Lee, Wan Seob Kim
Clin Exp Pediatr. 1994;37(5):628-635.   Published online May 15, 1994
Medical records of very low birth weight infants weighing less than 1500 grams at birth were reviewed and analyzed. One hundred and forty three infants who were admitted to neonatal intensive care unit of Presbyterian Medical Center, including those who were born and transferred from other hospitals, from January 1987 to December 1991 were examined and the following results were obtained; 1)...
Case Report
Furosemide-Induced Nephrocalcinosis in Very Low Birth Weight Infants
Clin Exp Pediatr. 1994;37(4):553-559.   Published online April 15, 1994
Renal calcifications are a recognized complication of furosemide therapy in premature infants. Particularly in infants with chronic lung disease, the use of this potent diuretic is associated with hypercalciuria, which may predispose the infant to medullary nephrocalcinosis and renal calculi. We experienced two cases of nephrocalcinosis in very low birth weight infants. One had bronchopulmonary dysplasia, pneumonia, patent ductus arteriosus,...
Original Article
Clinical Observation on Very Low Birth Weight Infants
Jong Soo Lee, Mi Young Yeo, Byung Hak Lim, Sang Geel Lee
Clin Exp Pediatr. 1992;35(1):44-50.   Published online January 15, 1992
Charts of very low birth weight infants weighing less than 1500 gms at birth were revieved and the results were analyzed. Infants were 152 in numbers, admitted to nursery in Fatima Hospital from January 1986 to December 1989 including outborns. Results were as follow: 1) The incidence of very low birth weight was 5.78/1000 among 26270 newborn infants. 2) Maternal high...
Clinical and statistical observation for very low birth weight infants.
Sung Shin Park, Ji Hee Jung, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1991;34(12):1629-1640.   Published online December 31, 1991
We made clinical and statistical observation of 90 very low birth weight infants who were admitted at Soonchunhyang university hospital during the 6 years period from January 1985 through December 1990. The result obtained were as follows: 1) The incidence of very low birth weight infant during 6 years period was 0.68%, and the mortality rate was 488/1000 very low birth weight infants. 2) There was no obvious...
Effect of fluid restriction on postnatal weight and outcome in very low birth weight infants.
Chul Lee, Hyeon Soo Lee, Ran Namgung, Dong Gwan Han
Clin Exp Pediatr. 1991;34(3):348-354.   Published online March 31, 1991
We studied 45 very low birth weight infants for change in birth weight, urine output, serum Na level, ventilatory support and outcome between two groups after fluid restriction therapy. Group 1 (n=17) were infants whose weight loss were more than 5% of birth weight. Group 2 (n=17) were infants whose weight loss were more than 5% of birth weight. 1) Group 1 had more fluid...
Clinical Survey of Very low Birth Weight Infant.
Seong Sook Jeon, Wha Mo Lee, Yang Sook Choi, Son Sang Seo
Clin Exp Pediatr. 1988;31(9):1120-1125.   Published online September 30, 1988
A clinical survey of Very Low Brith Weight Infant was done on 27,170 infants bom at II Sin Christian Hospital between Jan. 1 1983 and Dec. 31 1986. The results were as follows; 1) The incidence of VLBWI in the 27,170 births was 1.0%, and there was no annual variation. 2) Among 10,749 multiparaty there was a higher incidence of VLBWI (1.4%) compared to that in primiparity...
The Result of Intensive Care on the very Low Birth Weight Infants(1001~1500gm).
Seo Jeong Kim, Ran Namgung, Chul Lee, Dong Gwan Han
Clin Exp Pediatr. 1988;31(1):29-39.   Published online January 31, 1988
The clinical study on the results of intensive care was performed on the 137 very low birth weight infants with birth weight of 1001-1500 gram who were admitted to the neonatal intensive care unit of Severance hospital from 1981 to 1986. The results were as follows. 1) The range of gestational age of very low birth weight infants was from 22 to 40 weeks, most predominantly...
Clinical Observation on Very Low Birth Weight Infants.
Ran Ah Kim, Yeong Jee Kim, Kyung Hee KIm, Keun Lee
Clin Exp Pediatr. 1986;29(1):26-31.   Published online January 31, 1986
Charts of very low birth weight infants weighing less than 1,500 grams at birth were reviewed and the results analyzed. Infants were 107 in numbers, admitted to NICU, Ewha Womans University Hospital for the period of 4 years from July 1980 to June 1984 including outborns. Results were as follows: 1) Incidence of very low birth weight infant was 1....
Follow Up Study of the Low Birth Weight Infants Less than Birth Weight 1,500 grams.
Hyun Sook Yoon
Clin Exp Pediatr. 1984;27(7):648-657.   Published online July 31, 1984
The growth and development of very low birth weight infants was evaluated in 92 of 114 survivors out of 384 babies weighing less than 1,500 grams who were born from January 1976 to December 1979 in Il-Sin Hospital. The mean birth weight and gestional age were 1,378±15.2 grams and 31±0.6 wks. Apgar score 5 or more at five minutes were...
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