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Original Article
Serial M-mode Echocardiographic Assessment of Left Ventricular Function in Kawasaki Disease
Byung Ho Choi, Jin Kyung Kim, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1994;37(6):759-766.   Published online June 15, 1994
To investigate the effect of kawasaki disease on left ventricular function, we studied 92 patients with Kawasaki disease at initial visit, after 3 months (78 patients) and after 1 year (9 patients). Using serial M-mode echocardiogram, we obtained LVD(d) (left ventricular internal dimension at end diastole), LVD(s)(left ventricular internal dimension at end systole), FS(fractional shortening), ET(ejection time), VmCF(mean velocity of circumferential...
The Clinical Observation in Kawasaki Disease
Min-Young Park, Gye-Sik Shim, Sung-Ho Cha, Chang-Il Ahn
Clin Exp Pediatr. 1994;37(2):167-174.   Published online February 15, 1994
One-hundred ninty five cases with Kawasaki disease who diagnosed and treated at the Department of Pediatrics, Kyung Hee University Hospital from January 1985 to June 1993, were investigated for their clinical manifestations and laboratory findings, and cardiac complications. The results are as follows: 1) Most patients (92.8%) were under 5 years of the age. 2) Boys were more prevalent than girls, as a...
Changes of IgG Subclasses in the Sera of the Children with Kawasaki Disease
Seog Beom Cho, Sun Kyu Park, Pyoung Han Hwang, Jung Soo Kim, Sa Hyoung Choi
Clin Exp Pediatr. 1993;36(9):1197-1202.   Published online September 15, 1993
Kawasaki disease is an acute vasculitis of infancy and early childhood characterized by high fever, rash, mucositis, lymphadenopathy and coronary artery damage. The failure to indentify a causative organism using convetional culture and serological techniques, and the lack of response to antibiotics indicate that the disorder is probably not due to any known bacterial or viral pathogens. During...
The Soluble Interleukin 2 Receptor Levels in Kawasaki Disease
Keum Chun Kim, Dong Soo Kim
Clin Exp Pediatr. 1992;35(12):1657-1666.   Published online December 15, 1992
Kawasaki disease has been known as an acute febrile mucocutaneous lymph node syndrome since 1967. But its definite pathophysiology still remains unclear. In order to study the immunologic basis for immunologic abnormalities in this disease, we studied the level of soluble interleukin-2 receptor (sIL-2R), interleukin-6 (IL-6) and C-reactive protein (CRP) at the acute and convalescent phases of the disease, comparing...
The Factors on the Development of Coronary Arterial Involvement in Kawasaki Disease
Sang Yen Kim, Jong Hyun Kim, Jong In Byun, Won Bae Lee, Byung Churl Lee, Kyung Tai Whang, Kyong Su Lee, Sung Hoon Cho
Clin Exp Pediatr. 1992;35(10):1328-1335.   Published online October 15, 1992
In Kawasaki disease, coronary arterial involvement is an important prognostic factor. Many studies have reported about risk factors of coronary artery disease in Kawasaki disease. This study was designed to evaluate factors influencing coronary arterial involvement and to evaluate the effect of intravenous gammaglobulin (IVG) when admitted on the widely used criteria in Korea. Fiftyfour patients meeting the CDC criteria...
The Comparison of Coronary Arterial Dimensions Measured by Cross-sectional Echocardiography with Values Obtained by Coronary Angiography in Kawasaki Disease
Mi Jin Jung, Jung Yun Choi, Shung Il Noh, Yong Soo Yun, I Seok Kang
Clin Exp Pediatr. 1992;35(8):1102-1106.   Published online August 15, 1992
In order to assess accuracy of cross-sectional echocardiographic measurements of coronary arterial dimension, measured values of coronary arterial dimensions by cross-sectional echocardiography were compared with the angiographic results. Twenty eight patients with Kawasaki diseas (male: female= 3:1, age range, 7 months-8 years) were studied by both coronary arteriography and crossleft anterior descending coronary artery, and left circumflex coronary artery) were...
The Interleukin-6 Level in Kawasak Disease
Moon Kyu Kim, Dong Soo Kim
Clin Exp Pediatr. 1992;35(4):515-526.   Published online April 15, 1992
Kawasaki disease is an acute multisystemic disease affecting infants and children with prominent vasculitic features. Although there has been considerable progress in understanding the pathogenesis of this disease, the inciting cause remains unclear. It has been noticed that there were many immunologic abnormalities during the acute stage of Kawasaki disease. In the pres-ent study, we studied serum interleukin-6(IL-6), C-reactive protein(CRP),...
Treatment of Kawasaki Disease with Single High-dose Intravenous Gammaglobulin
Mi Koo Kang, Eun Young Cho, Young Hwue Kim, Ki Soo Kim, Young Seo Park, In Sook Park, Hyung Nam Moon, Chang Yee Hong
Clin Exp Pediatr. 1992;35(3):342-348.   Published online March 15, 1992
Kawasaki disease is an acute febrile illness of unknown origin and most frequently affects infants and children under 5 years of age. Coronary aneurysms are the most serious complications and 15-20% of patient develop coronary aneurysm. We studied 50 children who wre diagnosed as Kawasaki disease and treated simultaneously with single high-dose gammaglobulin (2 gm/kg/day) and aspirin at Asan Medical Canter...
The Clinical Observation in Kawasaki Disease
Young Jin Jang, Joong Gon Kim, Yong Soo Yun
Clin Exp Pediatr. 1992;35(3):330-341.   Published online March 15, 1992
The one-hundred thirty five cases with Kawasaki disease who wre diagnosed and treated at the department of pediatrics, Seoul National University Children뭩 Hospital from September 1984 to December 1990, were investigated for clinical pattrns and laboratory correlations. The results were as follows; 1) Most patients (86%) were under 4 years of the age. 2) boys wee more prevalent than girls, as a ratio...
A comparative study of therapeutic effect of combined treatment with aspirin and intravenous gammaglobulin versus aspirin alone in Kawasaki disease.
Sang Bong Lee, Eui Tak Oh, Kang Youl Bae, Hong Ja Kang, Woo Sik Chung, Kil Soo Kim
Clin Exp Pediatr. 1991;34(12):1664-1670.   Published online December 31, 1991
We compared the therapeutic effect of intravenous gamma globulin plus aspirin with that of aspirin alone in reducing the coronary aneurysms and changes of clinical courses in 57 children with Kawasaki disease who were admitted in Dae Dong hospital from Jul. 1987 to Jun. 1990 These 57 cases were divided into two groups: Group A:High dose aspirin (100 mg/kg/day) during febrile stage and then...
A Clinical Observation of Kawasaki Disease at High Risk of Coronary Artery Aneurysm.
Y.T Chung, M.Y Yeo, J.O Lee, B.H Lim, I.J Kang
Clin Exp Pediatr. 1991;34(11):1540-1546.   Published online November 30, 1991
Kawasaki disease is an acute febrile illness of unknown origin and its most serious complication is coronary aneurysms We compared the coronary arterial dilatated group with nondilatated group in clinical manifesta- tion laboratory test, electrocardiography in 90 children with Kawasaki disease, who were admitted to department of Pediatrics of Fatima Hospital from July 1985 to June 1990. The results were as follows. 1) Coronary arterial dilatation was...
Effect of immune globulin on the prevention of coronary artery aneurysm in Kawasaki disease.
Mi Jin Jung, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1991;34(5):668-676.   Published online May 31, 1991
We compared the efficacy of each modality of treatment group in reducing the frequency of coronary artery aneurysm in children with Kawasaki syndrome. Group 1 (26 cases)-aspirin alone: Group 2 (26 cases)-intravenous gamma globulin, 400 mg per kilogram of body weight per day for five consecutive days, plus aspirin; Group 3 (21 cases)-intravenous gamma globulin, single dose of 2.0 g per kilogram of body...
Comparison between Treatment with Aspirin Alone and the Combined Treatment with Aspirin and Intravenous gamma-Globulin in Kawasaki Disease.
Sang Yoon Ahn, Sun Yang Hong, Nam Soo Kim, Ha Baik Lee, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1990;33(10):1380-1387.   Published online October 31, 1990
Out of a total of 140 children hospitalized with the diagnosis of Kawasaki disease at the Depart- ment of Pediatrics, Hanyang University Hospital during the period of 9 years from July 1980 to July 1989, 68 cases were subjected to echcocardiographic examination at 10 to 15 days after the onset of illness, and these 68 cases were divided into two groups according the...
Three Cases of Kawasaki Disease Accompanied with Rare Clinical Menifestation.
Min Yong Oum, Sang Eun Lee, Jae Ock Park, Chang Hwi Kim, Sang Jhoo Lee
Clin Exp Pediatr. 1989;32(9):1300-1308.   Published online September 30, 1989
We experience 3 cases of Kawasaki disease accompanied with rare clinical manifestations. The first case was 6 year old boy who accompanied with hydrops of gallbladder and facial palsy. The second case was 7 month old boy who developed vesicles, crust, and desquamation of the BCG inoculation site. The third case was 18 month old boy who developed transverse groove (Bow’s line) of the...
A Clinical Study of Kawasaki Disease Complicating Coronary Aneurysm.
Chong Sung Chung, Byung Yul Lim, Sung Ho Cha, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(9):1240-1247.   Published online September 30, 1989
Kawasaki disease is an acute febrile illness of unknown origin and most frequently affects infants and children younger than age 5 years. Coronary aneurysms are most serious complication in Kawasai diseas and are developed in 15〜20% of patients. We studied 15 children Kawaski disease complicating coronary aneurysms, who were admitted to the Kyung Hee University Hospital during the period of January 1984 through January...
Abdominal Ultrasonographic Findings in Patients with Kawasaki Disease.
Ho Taek Kim, Chang Ho Hong, Chul Lee, Sung Kyu Lee, Pyung Kil Kim, Ki Kun Oh
Clin Exp Pediatr. 1988;31(3):348-354.   Published online March 31, 1988
Kawasaki disease, first reported in Korea in 1973, is now one of the disease commonly encountered in pediatric age group. It presents systemic symptoms including abdominal ones such as pain, nausea and vomiting, etc. There have been several case reports of hydrops of the gallbladder occuring concurrently with Kawasaki disease, and the abdominal symptoms of the disease are known to correlate with hydrops of...
A Case of Kawasaki Disease Compicated by Hydrops of Gallbladder.
Jung Sik Rhim, Chul Joo Lyu, Ki Sup Chung
Clin Exp Pediatr. 1988;31(1):124-127.   Published online January 31, 1988
The authors experienced a case of Kawasaki disease complicated by hydrops of the gallbladder in a 3-year old male patient. The main clinical features were colicky abdominal pain, vomiting, jaundice, fever and a palpable tender mass in RUQ in conjunction with the characteristic clinical manifestation of Kawasaki disease. The clinical diagnosis was confirmed by ultrasonography, and the patient was recovered by conserva- tive management without...
Clinical Observation of 44 Cases of Kawasaki Disease.
K H Chang, B H Lim, H J Suh, I J Kang
Clin Exp Pediatr. 1985;28(11):1097-1103.   Published online November 30, 1985
44 Cases of Kawasaki Disease in children who were admitted to department of pediatrics of Fatima Hospital, Daegu, Kore, from January 1980 to June 1984 were analysed and following results were obtained. 1)Most cases (79.5%) were under the 2 years of age. 2)The sex ratio of male to female was 2.5:1. 3)The main clinical symptoms observed were fever over 5...
Clinical Obseervation of 12 cases of Kawasaki Disease.
Bok Yang Pyun, Chang Woo Koh, Dong Whan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1981;24(3):245-256.   Published online March 15, 1981
Kawasaki Disease of Mucocutaneous Lymph Node Syndrome, first described by Kawasaki in 1967, is an acute febrile disease of unknown etiology. Until recently, more than 17,000 cases of this disease have been listed in the survey of a special study group supported by the Japanese Ministry of Health and Welfare. And a number of cases have been reported even outside...