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Original Article
A clinical study on influences of premature rupture of membranes in the newborn infant.
Ji Sun Cho, Young Sun Ko, Soon Ok Byun, Ji Sub Oh
Clin Exp Pediatr. 1991;34(2):180-189.   Published online February 28, 1991
A clinical study was made on 607 newborns of mothers with premature rupture of membrane (PROM group) and 5,775 newborns of mothers without ruptured membrane Baptist Hospital from January 1987 to December 1989. The results are summarized as follows: 1) The overall incidence of PROM was 9.5% with little yearly variations. 2) 11.9% of all babies with PROM were bom prematurely, significantly higher than the incidence of control...
A Case of Thanatophoric Dysplasia.
Eun Sil Kim, Hyun Joo Choi, Mi Ran Park, Jae Yun Kim, In Sang Jeon, Kwang Jeon Kim, Bum Woo Yum
Clin Exp Pediatr. 1990;33(11):1593-1597.   Published online November 30, 1990
Thanatophoric dysplasia is a short limb dwarf condition in which respiratory distress is responsible for death in the first hours or days after birth. We experienced a case of thanatophoric dysplasia who presented striking disproportion of trunk and extremities. The head was relatively large, the trunk was narrow and normal length, and the extremities were markedly shortened. The radiologic feature of this dysplasia was characteristic....
A Clinical Study on Neonatal Polycythemia.
Gyu Ja Jeong, Hye Jin Lee, Yaung Sook Choi, Son Sang Seo
Clin Exp Pediatr. 1990;33(11):1495-1502.   Published online November 30, 1990
We observed 34 cases of newborn, who were diagnosed as having polycythemia, out of 3,312 newborns who were admitted to our nursery between January 1, 1989 and December 31, 1987. The following results were obtained; 1) The incidence of neonatal polycythemia was 1% and male to female ratio was 1.8:1. The birth weight of 2000 g to 2500 g was the most common (35.3%). 2) Gestational age...
A Study of Clinical Observations in Neonatal Sepsis.
E S Kim, K H Kim
Clin Exp Pediatr. 1990;33(9):1180-1187.   Published online September 30, 1990
We have experienced 67 cases of neonatal sepsis confirmed by clinical symptoms and blood culture between July 1983 and June 1988 at Ewha university hospital. The results obtained were as follows: 1) The incidence of septicemia was 0.6%. The sex ratio of patients was 0.97:1 with 33 males and 34 females. 2) The incidence was higher in preterm babies than in full term babies and higher in...
Studies on the Change of Pulmonary Artery Pressure in Early Neonatal Period.
Jung Ae Kim, Yung Kyun Oh, Byung Kiu Park, Hee Shang Youn, Myung Kul Yum
Clin Exp Pediatr. 1990;33(8):1081-1086.   Published online August 31, 1990
The change of postnatal pulmonary artery pressure was studied with doppler echocardiography and phonocardiogram in 40 normal full term neonates before 6 hours, between 6 〜 24 hours, 24~48 hours, 48-72 hours, 72 hours 〜 7 days. The results of study were as follows: Pc-To interval (sec) decreased (0. 071 ±0.002, 0.062±0.003, 0.050±0.002, 0.037±0.007, 0.027±0.003) and AT/ET ratio increased (0. 24±0.01, 0.30±0.02, 0.40±0.03, 0.40±0.04,...
Seventeen Years Experience on Inborn Errors of Metabolism A Study for Future Development of Inborn Errors of Metabolism in Korea.
Hong Jin Lee, Hyung Ro Moon
Clin Exp Pediatr. 1990;33(8):1031-1036.   Published online August 31, 1990
In Korea, the study of inborn errors of metabolism is very primitive. Even the incidence and prevalence of the disease of inborn errors of metabolism are not known in Korea. We have done this study of inborn errors of metabolism in Korea and concluded that: 1) The varieties and incidences of inborn errors of metabolism in Korea might be relatively diverse and high. 2) Nation wide mandatory...
A study of neonatal cholestasis and cytomegalovirus infection.
Moon A Kim, Ki Sup Chung
Clin Exp Pediatr. 1989;32(11):1474-1481.   Published online November 30, 1989
A clinical assessment of 25 patients with neonatal cholestasis caused by cytomegalovirus infection who were admitted to the Department of Pediatrics, Yonsei University College of Medicine from January 1983 to July 1988 was performed. The results were as follows: 1) The patients with neonatal cholestasis caused by cytomegalovirus infection were 19% of the total patients with neonatal cholestasis from January 1983 to July 1988 and were...
Change of Auditory Brainstem Response(ABR) on Neonatal Asphyxia.
Jeong Sam Jeon, Chong Woo Bae, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(10):1391-1396.   Published online October 31, 1989
Neonatal asphyxia is insult to the newborn due to lack of oxygen or perfusion to various organs. It is associated with tissue hypoxia, especially brain. So hypoxic-ischemic brain injury is the most important complication known as hypoxic-ischemic encephalopathy. The EEG as well as various evoked potentials (auditory, visual and somatosensory) may assist in evaluating the severity of the damage. This study was undertaken to...
The Effect of Oxytocin in Induced Labour on Neonatal Jaundice.
Seung Koog Kim, Chong Woo Bae, Young Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(10):1337-1344.   Published online October 31, 1989
This study was undertaken to evaluate the relationship between oxytocin which was administered to pregnant women during delivery or pregnancy and hyperbilirubinemia of newborn. Among new- borns who were delivered in KHUH from Feb. 1987 to Sep. 1987 and showed hyperbilirubinemia whithin 1 week after birth without definite etiologies of hyperbilirubinemia of newborn, 30 newborns delivered by induced labour and 30 newborns delivered by...
Clinical Observation and Electroencephalographic Findings relatee to Prognostic factor in Neonatal Seizure.
Soo Chun Kim, Jung Sam Jeon, Chong Woo Bae, Sa Joon Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(6):816-822.   Published online June 30, 1989
To study the clinical prognosis of the neonatal seizure, we carried out a retrospective review on medical records of 40 neonates who were admitted to the Dept. of Pediatrics, Kyung Hee University Hospital between January 1979 and December 1986. The results from the study are summarized as follows 1) Male to female ratio were 1.8:1. In 50.0%(20/40) of newborn infants, neonatal seizure was detected under...
Neonatal Necrotizing Enterocolitis.
Min Sook Um, Jae Won Huh, Yun Joo Chung
Clin Exp Pediatr. 1989;32(4):518-524.   Published online April 30, 1989
We made a review on the 12 cases of neonatal necrotizing enterocolitis admitted to the nursery of Gospel hospital of Kosin Medical College from September, 1984 to June, 1987 and reseults were; 1) Although there were more infants weighing more than 2500 gm with neonatal necrotizing enterocolitis, the prevalence rate of the disease was higher in low birth weight. 2) The half of term...
Sepsis Associated with Total Parenteral Nutrition in the Neonates.
Jae Won Huh, Jo Sam Koo, Yun Joo Cheung
Clin Exp Pediatr. 1989;32(4):495-499.   Published online April 30, 1989
The retrospective study was performed on the 33 neonates with TPN admitted to the nursery of Gospel Hospital of Kosin medical college between January 1985 and Jun 1987. 1) The incidence of sepsis during TPN was 27% and it was related only to the duration of TPN received for more than 7 days. 2) Major organisms were S. epidermids (30%), Enterobacter cloacae (20%). 3) Major...
Doppler Echocardiographic Studies on Hemodynamic Changes in Early Neonatal Period.
Myung Kul Yum
Clin Exp Pediatr. 1989;32(2):158-164.   Published online February 28, 1989
Postnatal circulatory changes were studied with doppler echocardiography in 40 normal full term neonate before 6 hours, between 6 and 24 hours, and after 24 hours of age. The results of study were as follows; 1) Pulmonary artery flow velocity integral per minute which means total systemic blood flow increased during those period (854±58, 1027±128, 1198±57 cm/min). 2) Flow velocity integral per minute in ascendiing...
Influences of Premature Rupture of Membranes on the Newborn Infant.
Kyoung Sim Kim, Young Ok Park, In Sung Lee, Ki Bok Kim
Clin Exp Pediatr. 1989;32(2):149-157.   Published online February 28, 1989
A comparative study on the frequencies of premature birth, neonatal sepsis, asphyxia, perinatal death and respiratory distress syndrome was carried out between 1309 newborns with premature rupture of membranes (PROM) and the normal group of 4636 newborns without PROM among all 5945 babies delivered at Kwangju Christian Hospital for the 2-year period starting from March 1985. The results are sumrnarized as follows: 1) The overall...
A Case of Transient Neonatal Diabetes Mellitus.
Hye Hyun Kim, Kyung Ha Ryu, Keun Lee
Clin Exp Pediatr. 1988;31(10):1346-1349.   Published online October 31, 1988
Transient Neonatal D.M. is rare disease which is characterized by letharginess, dehydration and weight loss with severe hyperglycemia. It occurs frequently which small for data infant and recovers spontaneously if appropriate insulin treatment was taken. We had expirienced a case of Transient Neonatal D.M. in 15 days old female infant. The review of the literature was made briefly.
A Case of Hemolytic Disease of Newborn due to Anti-E.
Sang Keun Oh, Youn O Park, hyun Sook Seo, Mi Sook Park, Young Chul Lee, Hee Dae Park, Hee Joo Lee
Clin Exp Pediatr. 1988;31(8):1059-1063.   Published online August 31, 1988
A 2-day-old male infant was admitted to the Incheon Christian Hospital due to severe jaundice. He was a third baby and his Rh phenotype was CcDEe. The direct antiglobulin test of the infant was strong positive. Eluates that were made from the infanfs elder brother and sister were both CDe. Her two previous infants showed no evidence of erythroblastosis. She had a past...
Normal TSH Levels in Neonates by TSH Screening test.
Jae Won Song, Jong Lin Rhi, Sei Won Yang, Jung Hwan Choi, Chong Ku Yun, Hyung Ro Moon, Bo Youn Cho, Chang Soon Koh
Clin Exp Pediatr. 1988;31(6):754-761.   Published online June 30, 1988
In 110 term neonates without perinatal problems who were bom in SNUH, blood TSH levels were measured by TSH screening test for congenital hypothyroidism. The results are as follows 1) Normal TSH level was 14.8±7.8 µU/ml, 8.8±4.7 µU/ml, and 6.5±2.7 µU/ml in neonates of age 0 〜24 hours, 24—48 hours, and 48〜72 hours respectively, and all TSH values in neonates of age 48〜72 hours were...
Analysis for Causative Agents in Neonatal Sepsis.
Jung Sook Hong, Ki Ji Lee, Shul Hoe Koo, Yun Joo Cheung
Clin Exp Pediatr. 1988;31(1):22-28.   Published online January 31, 1988
To determine causative organisms and their antibitotics sensitivities in neonatal sepsis, we made a review on the 26 cases of neonatal sepsis. Patients were admitted to the special care nursery of Gospel hospital of Kosin Medical College during the period of 2 years from January 1985 to December 1986 and the results were: 1) The most frequently growing organism was Staphylococcus epidermidis (34.6%) and drugs...
The Effect of Hepatitis B Vaccination on Newborns of Hepatitis B Carrier Mothers.
Ho Taek Kom, Pyung Kil Kim, Chang Ho Hong, Chul Lee
Clin Exp Pediatr. 1987;30(11):1228-1235.   Published online November 30, 1987
The transmission of hepatitis B virus (HBV) from carrier mothers to their infants is a serious problem in many countries and the transmission rate is reported to be as high as 60%. The best preventive method of perinatal transmission is hepatitis B immune globulin (HBIG) which confers a passive immunity and HB vaccine which confers an active immunity. However, the exact dosage and the...
Case Report
Neonatal Tetanus Treated with Intermittent Positive-Pressure Ventilation.
Ran Namgung, Chuhl Joo Lyu, Chul Lee, Youn Ha Kang, Dong Gwan Han
Clin Exp Pediatr. 1987;30(6):671-676.   Published online June 30, 1987
We report our experience with Neonatal Tetanus treated with Intermittent Positive-Pressure Ventilation combined with Neuromuscular blockade and high dose diazepam. Duration of mechanical ventilation was ranged from 15 days in case 1 to 36 days in case 2. Pneumonia with atelectasis and sepsis due to pseudomonas cepacia was complicated in case 2, but cleared up with sensitive antibiotics and vigorous physiotherapy. Muscle relaxation and sedation...
Original Article
Clinico-Hematologic Observation of Neonatal Hemolytic Disease due to Minor Blood Group Isoimmunization.
Chong Woo Bae, Yong Mook Choi, Chang Il Ahn, Hyun sok Chi
Clin Exp Pediatr. 1987;30(5):504-510.   Published online May 31, 1987
The isoimmune hemolytic diseases of the newborn due to minor blood group are characterized by the abnormal titer of minor group antibody in mother’s serum and neonatal progressive jaundice caused by isoimmune hemolytic anemia. This report present the clinico-hematologic features of six cases of hemolytic diseases of newborn due to minor blood group isoimmunization who were admitted to the Kyung Hee university Hospital and presented...
Three Cases of Spontaneous Neonatal Gastric Perforation.
Wha Mo Lee, Hye Jin Lim, Son Sang Seo, Jung Woo Yang
Clin Exp Pediatr. 1987;30(4):450-455.   Published online April 30, 1987
Three cases of spontaneous neonatal gastric perforation seen at II Sin Christian Hosp, between 1981 and 1985 were seen in all reported with brief literature review. Of the three cases, two occurred in males and one in female. One case was prematurity and other two cases were small for gestational age. All perforations occurred within first five days. Respiratory difficulty and abdominal distension with radiographic...
Clinical Observations on Neonatal Sepsis.
Beyong Il Kim, Hae Lim Chung, Yoon Deok Kim, Weon Soon Park, Son Moon Shin, Hoan Jong Lee, Jung Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1987;30(2):130-138.   Published online February 28, 1987
We studied the 73 cases of proven neonatal sepsis among 11,102 newborn infant under 1 month of age, admitted to the pediatric ward, the nursery and the NICU of Seoul National University Hospital from Jan. 1, 1980, to Dec. 31, 1985. The results were as follows: 1) The incidence was 6.6/1000 live births. Incidence of male babies was 8.3/1000 live births. The morbidity rate of...
Clinical observation in 72 Cases with Neonatal Sepsis.
Jae Seung Yang, Ran Namgung, Chul Lee, Dong Gwan Han
Clin Exp Pediatr. 1986;29(12):1309-1313.   Published online December 31, 1986
Since the clinical features of neonatal sepsis were first reported by Dunham in 1933, there have been many studies. But because of the uncertain early symptoms and it’s rapid progression, the mortality rate of neonatal sepsis runs still high. We are reporting 72 cases of neonatal sepsis confirmed by clinical symptoms and blood culture studies over 3 years and 5 months between...
Early neonatal Mortality Rate in Newborn Nursery.
Woo Sup Shim, Yoon Taik Kim
Clin Exp Pediatr. 1986;29(10):1087-1094.   Published online October 31, 1986
In 5,162 newborns who were born in National Medical Center during the period from January 1980 to December 1984, the authors investigated the early neonatal mortality within 7 days after birth and some factors associated with it. 1) The early neonatal mortailty rate within 7 days after birth was in average 17.4 and. there was no significant difference between male...
Clinical Studies on Neonatal Jaundice and Exchange Transfusion.
Byoung Hun Kim, Soo Yup Lee, Jeh Hoon Shin, Kyu Hwan Lee, Soo Jee Moon, Chong Moo Park
Clin Exp Pediatr. 1986;29(5):535-542.   Published online May 31, 1986
Jaundice occurs rather frequently in neonatal period, and yet the irreversible complication, kernicterus, may occur in severe cases with pathologic jaundice, from which the patients are at high risk for mental retardation, cerebral palsy, and even death. To prevent this complication, aggressive measures have been used for the neonatal janudice, such as phototherapy and exchange transfusion. Exchange transfusion has been...
Clinical Study on Anemia in Neonatal Period.
Jin Young Lee, Hong Kun Kim, Woo Gil Lee, Soo Jee Moon, Hahng Lee, Keun Soo Lee
Clin Exp Pediatr. 1986;29(5):525-534.   Published online May 31, 1986
Neonatal period is marked with constantly changing hematologic process due to a number of physiologic and pathologic factors, and with risk of underdiagnosis or misdiagnosis of anemia of various causes. Therefore, prompt diagnosis of anemia and accurate identification of its underlying causes would be essential to arrive at the appropriate management and to avoid occasional serious complications. 104 full term...
Progostic Factors in Neonatal Asphyxia.
Hye Li Chung, Wan Sup Kwak, Haeng Mi Kim, Doo Hong Ahn
Clin Exp Pediatr. 1986;29(4):420-425.   Published online April 30, 1986
A clinical study was conducted on 30 term babies with neonatal asphyxia, who were admitted to Pediatric Department of Kyungpook National University Hospital during 2years period from May 1983 to April 1985. Of the 20 cases returned to follow up, 15 cases were neurodevelopmentally normal but 5 cases were retarded with neurologic disability. Retarded case revealed higher incidence of severe asphyxia...
Case Report
2 Cases of Herpes Simplex Virus Infection in the neonates.
Kyung Hyo Kim, Jeong Wan Seo, Kyung Hee Kim, Keun Lee, Ki Sook Hong, Mi Ae Lee, Woon Sup Han, Ok Kyung Kim, Yung Oh Shin, Sung Bok Paik
Clin Exp Pediatr. 1986;29(1):101-107.   Published online January 31, 1986
Herpes simplex virus infection in the newborn is generally thought to be associated with a grave prognosis in terms of mortality and severe neurologic sequelae among survivors. Most neonatal herpes infection are due to type 2 herpes virus hominis, acquired either by ascending infection from the mother’s genital area to the intrauterine infant after premature rupture of membrame, or by...
Original Article
A Study on Calcium Metabolism in Newborn Infants.
Jin Heon Kim, Chang Soo Ra
Clin Exp Pediatr. 1985;28(10):967-976.   Published online October 31, 1985
A thorough understanding of calcium homeostasis and metabolism in newborn infants is necessary in the evaluation of any newborn infant with hypocalcemia. Author studied the levels of urinary calcium and phosphorus during the 48 hours after birth, and also studied before and after feeding during the 24 hours after birth in 19 normal term infants. And serum calcium, phosphorus, parathormone,...
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