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Volume 56(4); Apr 2013
Review Article
Endoscopic treatment of vesicoureteral reflux in pediatric patients
Jong Wook Kim, Mi Mi Oh
Korean J Pediatr. 2013;56(4):145-150.   Published online April 22, 2013

Endoscopic treatment is a minimally invasive treatment for managing patients with vesicoureteral reflux (VUR). Although several bulking agents have been used for endoscopic treatment, dextranomer/hyaluronic acid is the only bulking agent currently approved by the U.S. Food and Drug Administration for treating VUR. Endoscopic treatment of VUR has gained great popularity owing to several obvious benefits, including short operative time,...

Original Articles
Expression of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ in the lung tissue of obese mice and the effect of rosiglitazone on proinflammatory cytokine expressions in the lung tissue
Seung Lok Ryu, Jae Won Shim, Duk Soo Kim, Hye Lim Jung, Moon Soo Park, Soo-Hee Park, Jinmi Lee, Won-Young Lee, Jung Yeon Shim
Korean J Pediatr. 2013;56(4):151-158.   Published online April 22, 2013
Purpose

We investigated the mRNA levels of peroxisome proliferator-activated receptor (PPAR)-α, PPAR-γ, adipokines, and cytokines in the lung tissue of lean and obese mice with and without ovalbumin (OVA) challenge, and the effect of rosiglitazone, a PPAR-γ agonist.

Methods

We developed 6 mice models: OVA-challenged lean mice with and without rosiglitazone; obese mice with and without rosiglitazone; and OVA-challenged obese mice with and...

p-Cresyl sulfate and indoxyl sulfate in pediatric patients on chronic dialysis
Hye Sun Hyun, Kyung Hoon Paik, Hee Yeon Cho
Korean J Pediatr. 2013;56(4):159-164.   Published online April 22, 2013
Purpose

Indoxyl sulfate and p-cresyl sulfate are important protein-bound uremic retention solutes whose levels can be partially reduced by renal replacement therapy. These solutes originate from intestinal bacterial protein fermentation and are associated with cardiovascular outcomes and chronic kidney disease progression. The aims of this study were to investigate the levels of indoxyl sulfate and p-cresyl sulfate as well as the...

Occurrence and characterization of oseltamivir-resistant influenza virus in children between 2007-2008 and 2008-2009 seasons
Seoung Geun Kim, Yoon Ha Hwang, Yung Hae Shin, Sung Won Kim, Woo Sik Jung, Sung Mi Kim, Jae Min Oh, Na Young Lee, Mun Ju Kim, Kyung Soon Cho, Yeon Gyeong Park, Sang Kee Min, Chang Kyu Lee, Jun Sub Kim, Chun Kang, Joo Yeon Lee, Man Kyu Huh, Chang Hoon Kim
Korean J Pediatr. 2013;56(4):165-175.   Published online April 22, 2013
Purpose

There was a global increase in the prevalence of oseltamivir-resistant influenza viruses during the 2007-2008 influenza season. This study was conducted to investigate the occurrence and characteristics of oseltamivir-resistant influenza viruses during the 2007-2008 and 2008-2009 influenza seasons among patients who were treated with oseltamivir (group A) and those that did not receive oseltamivir (group B).

Methods

A prospective study was conducted...

The hybrid perventricular closure of apical muscular ventricular septal defect with Amplatzer duct occluder
Soo Jin Kim, June Huh, Jin Young Song, Ji-Hyuk Yang, Tae-Gook Jun, I-Seok Kang
Korean J Pediatr. 2013;56(4):176-181.   Published online April 22, 2013
Purpose

Apical muscular ventricular septal defects (MVSDs), especially in small infants, can be difficult to manage using surgical and percutaneous closure. An intraoperative perventricular procedure is a good option for closing apical MVSDs in small children with or without associated cardiac anomalies. We evaluated the results of hybrid perventricular closure of apical MVSDs performed using an Amplatzer duct occluder (ADO).

Methods

We retrospectively...

Case Reports
An unusual cause of duodenal perforation due to a lollipop stick
Mi Jin Kim, Jeong Meen Seo, Yoon Lee, Yoo Min Lee, Yon Ho Choe
Korean J Pediatr. 2013;56(4):182-185.   Published online April 22, 2013

Children have a natural tendency to explore objects with their mouths; this can result in the swallowing of foreign objects. Most ingested foreign bodies pass uneventfully through the gastrointestinal tract. However, some foreign bodies cause obstruction or perforation of the gastrointestinal tract, requiring surgical intervention. Perforation of the gastrointestinal tract may be associated with considerable morbidity and mortality. The most...

Lung torsion after tracheoesophageal fistula repair in an infant
Eun Mi Yang, Eun Song Song, Hae in Jang, In Seok Jeong, Young Youn Choi
Korean J Pediatr. 2013;56(4):186-190.   Published online April 22, 2013

Lung torsion is a very rare event that has been reported in only 9 cases in the pediatric literature but has not yet been reported in Korean infants. We present a case of lung torsion after tracheoesophageal fistula repair in an infant. Bloody secretion from the endotracheal tube and chest radiographs and computed tomographic scan results indicated lung torsion. Emergency...