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Volume 34(11); Nov 1991
Original Articles
Clinical study on metabolic liver diseases in infancy and childhood.
Jeong Lim Kim, Ki Sup Chung
J Korean Pediatr Soc. 1991;34(11):1477-1493.   Published online November 30, 1991
The liver plays a central role in synthetic, degradative, and regulatory pathways involving the metabolism of carbohydrates, protein, lipid, mineral, and vitamins. There are many metabolic abnormalities or specific enzyme deficiencies that affect the liver. The clinical manifestations of metabolic diseases of the liver mimic infections, intoxications, and other systemic diseases. The comprehension of the pathogenesis on the inborn metabolic errors and early...
The effect of dietary fats of immune response in sublethally irradiated rats.
Soon Hwan Oh, Dong Soo Kim, Hae Won Nam, Juhn Kyu Loh
J Korean Pediatr Soc. 1991;34(11):1494-1504.   Published online November 30, 1991
To investigate the effect of dietary fats on cellular immune response in the immunosuppressed rats, different compositions in the quality and quantity of dietary fats were fed to sublethally irradiated male rats. The results are as follows; 1) After 2 weeks of irradiation, the mean body weight of the fat free dietary group was significant- ly lower than the com oil group. The organ weight, especially...
The effect of ultrasonic nebulized salbutamol in the first attacked wheezy infants.
Soo Young Kweon, Young Mi Hong, Gyung Hee Kim, Seung Joo Lee, Keun Lee
J Korean Pediatr Soc. 1991;34(11):1505-1511.   Published online November 30, 1991
Wheezing is one of the most common symptom in the first 2 year of life. Although the effect of bronchodilator in wheezy infants was still debating, various form of bronchodilator has been tried untill now. This study was done to estimate the value of ultrasonic nebulized salbutamol as a bronchodilator test and maintenance therapy compared to epinephrine and aminophylline in 44 wheezy infants below 24...
A comparison between remission and nonremission groups of hepatitis B virus-associated membranous nephropathy in children.
Kang Yong Park, Hye Won Park, Yon Ho Choe, Tae Sun Ha, Il Soo Ha, Yong Choi, Kwang Wook Ko, Hyun Soon Lee, Yong Il Kim
J Korean Pediatr Soc. 1991;34(11):1512-1518.   Published online November 30, 1991
We analyzed medical records of 35 patients with Hepatitis B virus-associated Membranous Nephropathy proven by kidney biopsy at SNUCH from Jan. 1975 to Jun. 1990. Clinical presentation, laboratory and pathologic findings were compared between remission group (who are free of proteinuria and edema in current status) and nonremission group (who have either proteinuria or edema). Age at onset was younger in remission group (4.51 ±2.93...
A measurement of measles antibody titer in pediatric age group.
Min Hyea Kim, Jee Eun Lee, Jung Weon Seo, Young Mee Hong, Kyung Hee Kim
J Korean Pediatr Soc. 1991;34(11):1519-1525.   Published online November 30, 1991
We measured the degree of immunity of 155 childrens with the age from birth to 12 years to measles antibody titer by enzyme-linked immunosorbent assay (ELIZA) for determine the proper age the Measles vaccination. The results were as follows; 1) By age group, 64% of the children was positive for Measles IgG antibody with the age between 1 and 2 months and 17% of the children with...
Mechanical ventilator care in the newborn infants.
Young Pyo Chang, Yong Won Park, Won Soon Park, Jung Hwan Choi, Chong Ku Yun
J Korean Pediatr Soc. 1991;34(11):1526-1533.   Published online November 30, 1991
The widespread introduction of mechanically assisted ventilation into the neonatal intensive care during the 1960s substantially improved the outcome of sick newborn infants, particularly those with respiratory disorders. We studied the clinical features of 82 neonates, who were treated with mechanically assisted ventilation in Neonatal Intensive Care Unit (NICU) at Seoul National Univer- sity Children’s Hospital from January 1986 to August 1989 (the second...
Clinical study on the factors used in the diagnosis of heart failure.
Dong Chul Park, Seok Min Choi, Jun Hee Sul, Sung Kyu Lee, Dong Shik Chin
J Korean Pediatr Soc. 1991;34(11):1534-1539.   Published online November 30, 1991
Heart failure is the state in which heart cannot produce the cardiac output required to sustain the metabolic needs of the body without evoking certain compensatory mechanisms. As these mecha- nisms become ineffective, increasingly severe clinical manifestations result. The diagnosis of conges- tive heart failure relies on several sources of clinical findings, including history, physical examination, and chest X-rays. For lack of uniform diagnostic...
A Clinical Observation of Kawasaki Disease at High Risk of Coronary Artery Aneurysm.
Y.T Chung, M.Y Yeo, J.O Lee, B.H Lim, I.J Kang
J Korean Pediatr Soc. 1991;34(11):1540-1546.   Published online November 30, 1991
Kawasaki disease is an acute febrile illness of unknown origin and its most serious complication is coronary aneurysms We compared the coronary arterial dilatated group with nondilatated group in clinical manifesta- tion laboratory test, electrocardiography in 90 children with Kawasaki disease, who were admitted to department of Pediatrics of Fatima Hospital from July 1985 to June 1990. The results were as follows. 1) Coronary arterial dilatation was...
A study on the immune reaction to the milk protein antigens in the postpartum mother, newborn baby, and children.
Soo chul Cho, Ju Hyung Kim, Hong Ro Lee, Jong San Lee, Pyoung Han Hwang, Jung Soo Kim
J Korean Pediatr Soc. 1991;34(11):1547-1558.   Published online November 30, 1991
There is continuing interest in the isotype response of human serum antibodies reactive with dietary proteins. This study was performed to clarify the humoral immune responses against cow’s milk proteins, 分-lactoglobulin and a-lactalbumin. Milk protein specific IgG, IgA, IgM, and IgG subclasses were measured using ELISA in the blood of various groups of age. The results were as follows: 1) Milk protein specific immunoglobulins were higher...
Clinical study on epileptiform discharge in children.
Wonil Park, Hong Jin Lee, Kung Ja Lee
J Korean Pediatr Soc. 1991;34(11):1559-1564.   Published online November 30, 1991
Seizures are the most common neurologic manifestation in childhood. The demonstration of epileptiform disshonge on EEG not only support clinical diagnosis but also aid the classification of epilepsy. 174 patients with recurrent seizure were taken EEG studies in Chuncheon Sacred Heart Hospital from Jan. 1985 to Dec. 1990. and 71 patients (40.8%) of them occured epilepiform discharge in inital EEG recording. The incidence of epilepiform pattern...
Epidemics of aseptic meningitis in Seoul area during 1989-90.
Eun young Cho, Mi Koo Kang, Soo Jong Hong, Ki Soo Kim, Young Seo Park, In Sook Park, Hyung Nam Moon, Chang Yee Hong
J Korean Pediatr Soc. 1991;34(11):1565-1572.   Published online November 30, 1991
We performed clinical and virological studies on 200 children with aseptic meningitis who had been admitted to the department of Pediatrics, Asan Medical Center from June, 1989 to August, 1990. The results were as follows; 1) There were total of 236 meningitis cases during this period, 13(5.5%) with bacterial meningitis, 3(1%) with tuberculous meningitis, 220(93.2%) with aseptic meningitis. Am이lg aseptic meningitis, 20(8.5%) were mumps meningitis. 2) Aseptic meningitis...
A case of primary hepatocellular carcinoma following vertical transmission of hepatitis B virus in a child.
Soo Kyoung Lee, Ki Sup Chung, Sun Won Hong, Chan Il Park
J Korean Pediatr Soc. 1991;34(11):1573-1580.   Published online November 30, 1991
Authors experienced a case of primary hepatocellular carcinoma in a 7 year 9 month old male patient, who was admitted to our hospital due to abdominal pain on right upper quadrant and anorexia during last two months. On family history, his mother was HBs Ag and HBe Ag carrier. On past history, he was admitted to a hospital due to persistant jaundice at...
A case of de Novo trisomy 12p syndrome.
Young Huuk Lee, Kir Young Kim
J Korean Pediatr Soc. 1991;34(11):1581-1586.   Published online November 30, 1991
A case of de novo trisomy 12p syndrome has deen experienced in newborn male child recently. This male child manifested normal birth weight, weak crying, poor sucking, generalized hypotonia, multiple congenital anomalies on face and digits, and progressive psychomotor retardation. The diagnosis was made on the basis of typical morphologic features and chromosomal study. As this is the first case in Korea, it is...
A case of 11q deletion syndrome.
Hye Kyeong Nam, Rhee Choi, Chang Hwi Kim, Sang Jhoo Lee
J Korean Pediatr Soc. 1991;34(11):1587-1592.   Published online November 30, 1991
11q-syndrome is a rare chromosomal anomaly. We experienced a case of llq deletion syndrome in a female infant. It was diagnosed by clinical features and chromosomal study. She had multiple anomalies such as flat occiput, hypertelorism, low set malformed ear, anteverted nostril, small carp-shaped mouth, micrognathia, hypertrophic pyloric stenosis and ventricular septal defect. Chromosomal study showed partial terminal deletion of the long arm of chromosome...
A case of cerebro-oculo-facio-skeletal syndrome.
Sung Shin Park, Ju Seok Maeng, Jae Ok Park, D. H Lee, S. J Lee
J Korean Pediatr Soc. 1991;34(11):1593-1597.   Published online November 30, 1991
COFS syndrome has been recognized as an autosomal recessive, apparently degenerative problem of the brian and spinal cord that usually manifest before birth. We experienced a female neonate of COFS syndrome, with multiple malformation wiich were, charaterized by low birth weight, microcephaly, microphthalmia, blepharophimosis, nystagmus, deep-set eyes, optic nerve hypoplsia, prominent nasal brideg, upper lip overlapping lower lip, micrognathia, retrognathia, widely set nipple, contracture of...
a case of type II lissencephaly; Walker-Earburg syndrome.
Ae Yong Kim, Jung Ho Lee, Yong Sub Kim, Kyeng Sook Cho, Jong Dai Jo
J Korean Pediatr Soc. 1991;34(11):1598-1604.   Published online November 30, 1991
Lissencephaly is a rare abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface. Three types of lissencephaly are recognized. Type I is characterized by microcephaly and dysmorphic facies. Type II usually lacks characteristic facies but exhibits macrocephaly from hydrocephalus, eye anomaly, and/or congenital muscular dystrophies. Type III is characterized by microcephaly without any characteristic dysmorphic facial features. We have experienced...
Two cases of thymolipoma.
Rhie Choi, Young Chang Kim, Hak Joo Cha, Sang Jhoo Lee, cheol Sae Lee, Jung Ki Ro, Seung Ha Yang, Chang Jin Kim
J Korean Pediatr Soc. 1991;34(11):1605-1611.   Published online November 30, 1991
Thymolipoma is a benign anterior mediastinal tumor composed of thymic tissue and mature adipose elements. The tumor is so rare that only 60 cases are reported in the world, and only 2 cases are reported in Korea. We have experienced two cases of thymolipoma in two thirteen-year-old boys. One had had chest pain and exertional dyspnea for 1 month but the other had no...
A case of xanthogranulomatous pyelonephritis misdiagnosed as Wilms' tumor.
Hyung Shim Chang, Hyung Doo Lee, Young Ho Lee, Woo Taek Kim, An Hong Choi, Jin Han Yoon, Jin Sook Jeong
J Korean Pediatr Soc. 1991;34(11):1612-1617.   Published online November 30, 1991
Xanthogranulomatous pyelonephritis is an uncommon form of pyelonephritis that is usually seen in middle-aged women and is much rarer in children. We report a case of focal xanthogranulomatous pyelonephritis in a 3-month-old boy, which misdiagnosed as Wilms’ tumor and successfully treated with total nephrectomy and long-term antibiotic therapy.
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