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Volume 46(4); Apr 2003
Clinical Lecture
Pulmonary Insufficiency after Repair of Tetralogy of Fallot : Prevention and Indications of Pulmonary Valve Replacement
Hyoung Doo Lee
J Korean Pediatr Soc. 2003;46(4):315-318.   Published online April 15, 2003
Premature Infants Follow-Up Program
Won Soon Park
J Korean Pediatr Soc. 2003;46(4):319-325.   Published online April 15, 2003
Original Articles
Relationship between Body Fat Distribution and Metabolic Risk Factors in Adolescents
Dal Hyun Kim, Tae Jung Seong, Young Jin Hong, Byong Kwan Son, Soon Ki Kim
J Korean Pediatr Soc. 2003;46(4):326-334.   Published online April 15, 2003
Purpose : The objectives of this study were to estimate the prevalence of obesity in adolescents; to study the association between obesity, blood pressure, and dyslipidemia; and to evaluate the superiority of waist circumference to waist/hip ratio(WHR) in central obesity. Methods : We selected 1382 adolescents(M : F=690 : 692) aged from 11 to 18 years(mean age; boys 15.0, girls 15.4)...
Differential Response of Surfactant Protein-A Genetic Variants to Dexamethasone Treatment
Eul Soon Kim, In Kyu Lee, Myung Ho Oh, Chong Woo Bae
J Korean Pediatr Soc. 2003;46(4):335-339.   Published online April 15, 2003
Purpose : Surfactant protein A(SP-A) is involved in surfactant physiology and structure, and plays a major role in innate host defense and inflammatory processes in the lung. Steroid therapy is widely used for mothers who threaten to deliver prematurely and also used commonly in the management of preterm infants with chronic lung disease. Two SP-A genes(SP-A1, SP-A2) and several alleles...
Allele Distribution and Frequency of Human Surfactant Protein-A2 in Korean Neonates
Nyeon Cheon Kim, Hee Chul Yoon, Jung Su Suk, Jung Ho Ko, Ook Joon Yoo, In Kyu Lee, Myung Ho Oh, Chong Woo Bae
J Korean Pediatr Soc. 2003;46(4):340-344.   Published online April 15, 2003
Purpose : We evaluated allele frequencies and distribution of surfactant protein A2(SP-A2) in Korean neonates in order to estimate the prevalence of RDS, to find out new SP-A alleles, and to establish new steroid therapy. Methods : Genomic DNA was extracted from 71 neonates and served as a template in PCR for genotype analysis. SP-A gene-specific amplications and gene-specific allele determinations...
Prognostic Value of Repeated Cerebrospinal Latex Agglutination Testing in Bacterial Meningitis
Soo Jeong Lee, So Hyun Ahn, Su Jin Cho, Hae Soon Kim, Seung Joo Lee
J Korean Pediatr Soc. 2003;46(4):345-350.   Published online April 15, 2003
Purpose : Bacterial meningitis is a serious infection of childhood associated with a significant morbidity and mortality. Repeated cerebrospinal fluid(CSF) examination is a useful prognostic indicator and a delayed sterilization is associated with a higher incidence of neurologic abnormalities. In this study we tried to determine the prognostic value of repeated CSF latex agglutination testing. Methods : We retrospectively evaluated 19...
A Clinical and Radiologic Study of Acute Focal Bacterial Nephritis in Children
Kum Ho Song, Kwon Hoe Huh, Ok Yeon Cho, Jae Hoon Sim, Do Jun Cho, Dug Ha Kim, Ki Sik Min, Ki Yang Yoo, Kwan Seop Lee
J Korean Pediatr Soc. 2003;46(4):351-357.   Published online April 15, 2003
Purpose : To raise awareness of the clinical importance of, and the need for proper management of acute focal bacterial nephritis(AFBN), we analyzed 22 AFBN patients and 22 other upper urinary tract infection patients by use of comparative studies. Methods : From January 2000 to May 2002, 22 AFBN patients aged from 1 month to 12 months were selected. As a...
Comparison of Effectiveness between Two Different Protocols of Treatment of IV γ-globulin in Idiopathic Thrombocytopenic Purpura
Jae Ho Jang, Moonsouk Lee, Mira Park, Kyuchul Choeh
J Korean Pediatr Soc. 2003;46(4):358-362.   Published online April 15, 2003
Purpose : Several methods of IV γ-globulin(IVG) infusion are effective in the treatment of autoimmune disease, including idiopathic thrombocytopenic purpura(ITP). But it is not known which method is more effective in the treatment of ITP. The effectiveness of these two methods of IVG infusion was studied in terms of platelet recovery rate, side effects and recurrence rate. Methods : Forty seven...
Overnight Growth Hormone Secretions and Sleep Patterns in Idiopathic Short Stature Children
Sang Young Seo, Kee Hyoung Lee, Baik Lin Eun, Chang Sung Sohn, Young Chang Tockgo, Chol Shin, Baek-Hyun Kim
J Korean Pediatr Soc. 2003;46(4):363-369.   Published online April 15, 2003
Purpose : Pharmacologic provocation test of growth hormone(GH) is a non-physiologic method and has several limitations for diagnosing growth hormone(GH) deficiency. Spontaneous GH release studies could be important in understanding the pathophysiology of children with poor growth but normal responses to GH provocation tests. Also, the relationship between nocturnal GH secretions and sleep patterns in short stature children is poorly...
The Relationship between House Dust Mite Sensitization and Month Birth Distribution in Children with Respiratory Allergy
Eun Kyeong Kang, Kyu Min Na, Hee Kang, Young Yoo, Young Yull Koh
J Korean Pediatr Soc. 2003;46(4):370-375.   Published online April 15, 2003
Purpose : It has been suggested that the exposure to aeroallergens during early infancy after birth is important in the subsequent development of sensitization and allergic diseases. In Korea, the level of house dust mites as one of the important aeroallergens is known to be the highest in autumn. The aim of this study was to test whether the distribution...
Plasma G-CSF and GM-CSF Concentration and Amount of Their Receptors on the Granulocyte in Kawasaki Disease
Young-Kyoung Yoo, Gibum Lee, Hyun-Hee Kim, Soo-Young Kim, You-Jeong Kim, Wonbae Lee
J Korean Pediatr Soc. 2003;46(4):376-381.   Published online April 15, 2003
Purpose : This study aimed to demonstrate the possible pathogenesis of granulopoiesis in patients of Kawasaki disease(KD) using quantitative analysis of G-CSF, GM-CSF and their CSFr. Methods : The plasma levels of G-CSF, GM-CSF, G-CSFr and GM-CSFr were studied in 14 patients in the acute phase of KD; 13 children with normal peripheral white blood cell counts were used as the...
Case Reports
A Case of Townes-Brocks Syndrome
Hong Seop So, Hyun Ju Choi, Hye Sun Yoon, Jin Soon Hwang, Keun Chan Sohn
J Korean Pediatr Soc. 2003;46(4):382-384.   Published online April 15, 2003
Townes-Brocks syndrome is an uncommon autosomal dominant condition first described by Townes and Brocks in 1972. We experienced a newborn female who presented with clinical findings of Townes-Brocks syndrome in an otherwise unaffected family. The patient showed the full spectrum of anomalies including anterior placed anus, triphalangeal thumb, preaxial polydactyly, pre-auricular tags, microtia without opening, sensorineural hearing loss and unilateral...
A Case of Coil Embolization in a 15-year-old Child with Pulmonary Sequestration
Hyo Bin Kim, Ja Hyung Kim, Jong Seung Lee, Soo-Jong Hong, Gyou Bo Sung
J Korean Pediatr Soc. 2003;46(4):385-388.   Published online April 15, 2003
Pulmonary sequestration is a rare congenital mass of nonfunctional pulmonary tissue that lacks a normal-connection with the bronchial tree or the pulmonary arteries. It is clinically asymptomatic but when it is complicated with recurrent infection, it needs to be treated. Conventionally, surgical removal was recommended, but these days we are trying new and less invasive techniques, such as arterial embolization....
A Case of Netherton's Syndrome in a Newborn
Eun-Hee Lee, Ellen Ai-Rhan Kim, Ki-Soo Kim, Beom-Jin Cho, Jai-Kyoung Koh, Soo-Young Pi
J Korean Pediatr Soc. 2003;46(4):389-392.   Published online April 15, 2003
Netherton's syndrome is an unusual disorder which consists of triad of ichtyosiform dermatosis, multiple defects of hair shaft and an atopic diathesis. The finding of bamboo hair is pathognomic in Netherton's syndrome and the ichthyosiform dermatosis may consist of either ichtyosis linearis circumflexa or congenital ichthyosiform erythroderma. Often, variability in the clinical features leads to a delay in diagnosis in...
A Case of Ileal Atresia with Hypertrophic Pyloric Stenosis
Byung Chan Lim, Jung Ha Lee, Kwang Sig Kim, Guk Myung Choi, Kyung Sue Shin, Jung Yun Hong, Youn Woo Kim
J Korean Pediatr Soc. 2003;46(4):393-396.   Published online April 15, 2003
Ileal atresia, a subtype of intestinal atresia, is one of the well-recognized causes of bowel obstruction in newborns. Prenatal diagnosis of intestinal atresia is very important in its management and outcome. Unfortunately, there are few cases of ileal atresia diagnosed prenatally, so more appropriate diagnoses and management plans are needed. As an associated gastrointestinal malformation with ileal atresia, hypertrophic pyloric...
Monosomy 21 Mosaicism in a Child with Dyserythropoiesis
Jae-Young Lim, Ji-Hyoun Seo, Myoung-Bum Choi, Chan-Hoo Park, Hyang-Ok Woo, Hee-Shang Youn
J Korean Pediatr Soc. 2003;46(4):397-399.   Published online April 15, 2003
All complete monosomy 21 appear to be lethal early in their development in humans and only survive in mosaic forms. Complete monosomy 21 is a very rare and usually debilitating genetic disorder. Partial monosomy 21 is also rare and is thought to constitute a clinical syndrome consisting of peculiar faces, hypertonia, psychomotor retardation, and slow growth. We experienced a case...
A Case of True Precocious Puberty Complicating Congenital Adrenal Hyperplasia
Su Jin Kim, Ju Suk Lee, Su Yung Kim
J Korean Pediatr Soc. 2003;46(4):400-403.   Published online April 15, 2003
Congenital adrenal hyperplasia(CAH) is a recognized cause of precocious pseudopuberty. Some children with CAH also develop true precocious puberty with early maturation of the hypothalamic-pituitary-gonadal axis. We review a case of CAH who eventually developed central precocious puberty nine months after initial treatment with corticosteroid. A 3-year-old boy visited complaining of rapid growth, a large penis and frequent penile erections....
Five Cases of Shaken Baby Syndrome
Ok Yeon Cho, Kwon Hoe Huh, Do Jun Cho, Dug Ha Kim, Ki Sik Min, Ki Yang Yoo, Yul Lee
J Korean Pediatr Soc. 2003;46(4):404-408.   Published online April 15, 2003
Shaken baby syndrome is a serious form of child abuse, mostly involving children younger than 2 years. It results from extreme rotational cranial acceleration induced by violent shaking. The characteristic injuries include subdural hemorrhage, retinal hemorrhage, and fracture of ribs or long bones. If physicians have no recognition of, or suspicion about, shaken baby syndrome, this syndome is difficult to...
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