Purpose : Henoch-Sch nlein purpura(HSP) is the most common and benign systemic vasculitis in children. Few reports have focused on worse outcomes of HSP in adults. The age of onset is suggested as a main risk factor. We assessed the characteristics of adolescent-onset HSP. Methods : We retrospectively analyzed 205 cases presented from Aug. 1993 to Oct. 2003. Patients were classified... |
Pediatric nephrotic syndrome is a well-known illness for its high relapsing rate. If we can predict the relapsing rate and the responses to the steroid therapy of individual patients with nephrotic syndrome, the predictability will be helpful in building a therapeutic plan. Here is my review of research articles on the risk factors for the prediction of relapsing nephrotic syndrome. |
Lymphoid interstitial pneumonia(LIP) is an uncommon process in childhood, and is characterized by interstitial accumulation of mature lymphocytes, plasma cells and reticuloendothelial cells. LIP is believed to have autoimmune or immunologic pathogenesis, because it is frequently associated with acquired immune deficiency syndrome, Epstein-Barr virus infection, common variable immunodeficiency. The patient described in this report had idiopathic thrombocytopenic purpura, Evans syndrome... |
Purpose : Most patients suffer from croup only once in a life time. However, a small group of patients suffer from it several times. A type of croup from which they suffer more than 3 times is called recurrent croup. The cause of recurrent croup has not been clearly described, but in recent years the allergic reaction is considered as a... |
Acyclovir is generally regarded as a safe and highly effective antiviral agent in normal, as well as in immunocompromised hosts. Major renal complication was unusual. However, reversible renal dysfunction has been reported. The impairment of renal nephropathy resulting from crystal formation in the renal tubules or the collecting ducts. But we experienced a case of immunocompetent patient who developed severe... |
We experienced a case of eisenmenger syndrome treated by simple surgical intervention. Eisenmenger syndrome refers to patients with congenital heart defects who have a systemic level of pulmonary arterial pressure and high pulmonary vascular resistance, with right-to-left or bidirectional shunting. Because a progressive rise in pulmonary vascular resistance may be better tolerated with an intracardiac communication, surgical repair in such patients... |
This study was taken to measure the serum aminotransferase level and it's correlation with clinical symptoms from Human Rotavirus gastroenteritis. This report is based on analysis of 434 patients who were admitted to the Pediatric department at Wonju Christian Hospital because of watery diarrhea and vomiting during 2-year period from July, 1991 to June 1993. The stool specimen on admission... |
Brachyecphaly is a kind of craniosynostosis. Because of premature closure of the coronal suture, the skull is shorter in the anteroposterior diameter but is widened with a high vault and the occiput and borehead are flattened. Diabetes insipidus had been reported in oxycephaly. We have experienced a case of central diabetes insipidus associated with brachcephaly. A brief review of related literatures... |
Eosinophilia is a common finding in premature babies during the neonatal period. Serial eosinophil counts were determined in 94 hospitalized, appropriately grown premature infants whose gestational ages ranged from 28 to 36 weeks. The incidence, sseverity and etiologic factors of eosinophila were retrospectively studied in premature infants, who were divided into three groups according to their gestational age. The results were... |
We experienced a case of nonbacterial thrombotic endocarditis in a 25-day-old male neonate, who was suffered from ASD, MR and congestive heart failure. He was died suddenly during recovery phase. The Post diagnosis was nonbacterial thrombotic endocarditis. We report with a brief review and its related literatures. |
Clinical observation was carried out for 147 patients with mucocutaneous lymph node syndrome(MCLS) who were admitted to the Department of Pediatrics, Wonju Cristian Hospital during the period from June, 1983 to June, 1992. A spinal tap was performed on 114 of these patients and the following results were obtained. 1) The incidence of aspetic meningitis in patients with MCLS was 52.6%.(60... |
Acute disseminated encephalomyelitis(ADEM) is an acute inflammatory demyelinating disease of the central nervous system. It is thought to be an autoimmune mediated disorder which occurs usually after viral or bacterial infections, or after immunization. The clinical manifestations reflect sudden onset of the diffuse involvement of the brain, spinal cord and the meninges. We experienced two cases of acute disseminated encephalomyelitis. The... |
Takayasu arteritis is a chronic inflammatory arteriopathy of unknown etiology affecting large vessels, particulary the aorta and its main branches. We experienced a case of Takayasu arteritis type III in a 9 years old girl. The diagnosis was made by physical examinations and digital subtration aortography(DSA) which showed occulsion of left subclavian artery and left renal artery and stenosis of abdominal... |
This study was conducted to find out the significance of nucleated red blood cell (NRBC) in neonates, especially associated with acute or chronic perinatal asphyxia. So, we compared NRBC counts in various neonatal groups, such as normal newborn, small for gestational age (SGA), premature, acute perinatal asphyxia, & hyaline membrane disease (HMD). In the first day of life, we examined... |
Tuberculous meningitis is still relatively common infectious disease of central nervous system in korea. The prognosis of tuberculous meningitis is closely related to the state at which treatment if started. Adenosine deaminase (ADA) is an enzyme which irreversibly hydrolyzes adenosine into inosine and ammonia. Recent investigations have suggested that the measurement of ADA activities in cerebrospinal fluid is useful in the... |
L-asparaginase is known as an effective anticancer drug in the induction chemotherapy of acute lymphocytic leukemia. The side effects or toxicities of L-asparaginase and prednisolone are hypersen- sitivity reaction, hepatotoxicity, pancreatitis and transient diabetes mellitus, CNS toxicity, disorder of coagulation system and mild cytotoxicity. We experienced a case of transient diabetes mellitus and diabetic ketoacidosis induced by L- asparaginase, prednisolone, vincristine and MTX administration in... |
Infants & children with hypothyrodism usually manifest variable skeletal abnormality. These features are the delay in longitudinal bone growth, the delay in epiphyseal maturation (=delay in bone age), the disturbances in bone mineralization and charateristic multiple stippled epiphysis (cretenoid epiphyseal dysgenesis). But many pediatrician have only concerned about the delay in epiphyseal maturation. Epiphyseal dysgenesis can be used a marker to find out the begining... |
Glanzmann’s thrombasthenia is rare congenital bleeding disorder of autosomal recessive trait. We experienced two cases of Glanzmann’s thrombasthenia in brother. The mother and elder brother had no history of bleeding tendency. But 10 year-old and 7 year-old younger brothers had frequent epistaxis, gum bleeding and easy bruisability. On platelet aggregation test, mother and elder brother appeared normal responses, but the younger brothers appeared no responses... |
We measured optical density of aqueous extracts of meconium and meconium stained amniotic fluid at 390 nm, 405 nm, 420 nm, 435 nm, 450 nm by spectrophotometry. We also applied the spectrophotometric method to the urine from 25 infants with clinical sign of meconium aspiration and from normal infants. The absorption band at 450 nm observed on the spectra of urine was estimated as... |
We reviewed a case of autoimmune hemolytic anemia caused by warm antibody in 7years old male patient. Diagnosis was established by clinical features, physical findings, laboratory findings, such as, CBC, Coombs’ test, fragility test, and bone marrow aspiration. Literatures were briefly reviewed. |
Alpha-fetoprotein(aFP) levels were studied in 20 neonatally hyperbilirubinemic children and 20 controls matched for gestational age. The mean aFP value of cord blood (119+58.2산g/ml) with hyperbilirubinemic children was significantly greater than that(79.6±40.8/zg/ml) for the control infants(P<0.001). At the age of 3 and 5 days the mean serum aFP in hyperbilirubinemic children were higher compared with the control group, the difference... |
We experienced a case of eosinophilic granuloma with multiple lesions on skull, ribs, vertebrae, tibia and pelvic bone. In addition, recurent bacterial meningitis was associated with CSF rhinorrhea probably due to osteolytic lesion of eosinophilic granuloma in the same patient. A brief review of literature was made. |