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Case Report
A case of atypical hemolytic uremic syndrome as an early manifestation of acute lymphoblastic leukemia
Dong Kyun Han, Hee Jo Baek, Young Kuk Cho, Chan Jong Kim, Myung Geun Shin, Hoon Kook, Tai Ju Hwang
Clin Exp Pediatr. 2010;53(2):253-257.   Published online February 15, 2010
Hemolytic uremic syndrome (HUS) is the most common cause of acute renal failure in children younger than 4 years and is characterized by microangiopathic hemolytic anemia, acute renal failure, and thrombocytopenia. HUS associated with diarrheal prodrome is usually caused by Shiga toxin-producing Escherichia coli O157:H7 or by Shigella dysenteriae, which generally has a better outcome. However, atypical cases show a...
Review Article
Acute renal failure in pediatrics
Hyewon Hahn
Clin Exp Pediatr. 2007;50(10):948-953.   Published online October 15, 2007
Acute renal failure is the generic term for an abrupt and sustained decrease in renal function resulting in retention of nitrogenous and non nitrogenous waste product. This may results in life threatening consequences including volume overload, hyperkalemia, and metabolic acidosis. Acute renal failure is both common and carries high mortality rate, but as it is often preventable, identification of patients...
Renal replacement therapy in children with acute renal failure
Kyung Hoon Paik
Clin Exp Pediatr. 2007;50(10):938-947.   Published online October 15, 2007
Many dialysis modalities such as peritoneal dialysis (PD), hemodialysis (HD) and continuous hemofiltration or hemodialysis (CRRT) are available for the management of pediatric patients with acute renal failure (ARF). PD is a relatively simple, inexpensive modality and can be used in hemodynamically unstable patients. But, it may not be the optimal therapy for patients with severe volume overload or life...
Original Article
Clinical characteristics of acute renal failure of rhabdomyolysis in children
Jae Hui Kim, Min Ji Goo, Jung Sook Yeom, Eun Sil Park, Ji Hyun Seo, Jae Young Lim, Chan Hoo Park, Hyang Ok Woo, Hee Shang Youn
Clin Exp Pediatr. 2007;50(3):277-283.   Published online March 15, 2007
Purpose : Acute renal failure (ARF) is an important complication of rhabdomyolysis. The purpose of this study was to identify the major causes of rhabdomyolysis in children and to identify the factors associated with the developmet of ARF. Methods : A retrospective chart review between January 1997 to June 2005 was conducted of 60 patients with a diagnosis of rhabdomyolysis. Rhabdomyolysis...
Renal manifestations in tuberous sclerosis complex
Il Cheon Jeong, Ji Tae Kim, You Sik Hwang, Jung A Kim, Jae Seung Lee
Clin Exp Pediatr. 2007;50(2):178-181.   Published online February 15, 2007
Purpose : The renal manifestations of tuberous sclerosis complex (TSC) are remarkably diverse, including polycystic kidney disease, simple renal cysts, renal cell carcinomas, and angiomyolipomas. All of these occur in children as well as adults in TSC. Angiomyolipomas, which can cause spontaneous life-threatening hemorrhages, are by far the most prevalent and the greatest source of morbidity. Here, we will address...
Case Report
A Case of Acute Renal Failure Caused by Rhabdomyolysis due to Hyperosmolar Nonketotic Coma in Children
Jeong Won Kwak, Jae Min Oh, Su Yung Kim
Clin Exp Pediatr. 2005;48(5):565-568.   Published online May 15, 2005
Hyperosmolar nonketotic coma complicated in diabetes mellitus has been a rare cause of rhabdomyolysis, although increasingly reported recently. Acute renal failure can be complicated in 15 percent of rhabdomyolysis patients, but is rare in the case of rhabdomyolysis caused by diabetic hyperosomolar nonketotic coma. We report a 14 years-old boy with acute renal failure complicated by rhabdomyolysis caused by diabetic...
Original Article
Outcome of Continuous Renal Replacement Therapy in Children
Yeon Jung Lim, Hyun-seung Jin, Hyewon Hahn, Sei Ho Oh, Seong Jong Park, Young Seo Park
Clin Exp Pediatr. 2005;48(1):68-74.   Published online January 15, 2005
Purpose : There is growing use of continuous renal replacement therapy(CRRT) for pediatric patients, but reports about the use and outcome of CRRT in children is rare in Korea. We report our experiences of CRRT in critically ill pediatric patients. Methods : We reviewed the medical records of 23 pediatric patients who underwent CRRT at Asan Medical Center between May 2001...
Case Report
A Case of Infantile Spasm Associated with Acute Renal Failure and Kwashiorkor after Ketogenic Diet
Young-Myoung Kim, Tae-Hong Kim, Jin-A Jung, Kyu-Geun Hwang
Clin Exp Pediatr. 2003;46(11):1131-1134.   Published online November 15, 2003
The ketogenic diet is a high-fat, low-protein, low-carbohydrate diet developed in the 1920s for the treatment of difficult-to-control seizures. Despite advances in both the pharmacotherapy and the surgery of epilepsy, many children continue to have difficult-to-control seizures. In this situation, a ketogenic diet should be considered as an alternative therapy. However, less attention has been paid to associated adverse events...
A Case of Kawasaki Disease Associated with Acute Renal Failure and Necrotizing Myositis
So Hyun Ahn, So Yun Shim, Sejung Sohn, Seung Joo Lee, Un Seop Han
Clin Exp Pediatr. 2003;46(2):207-209.   Published online February 15, 2003
Kawasaki disease is an acute febrile vasculitis affecting primarily infants and young children. In addition to the cardiovascular involvement, it may cause inflammatory changes in various organs and body systems : digestive, respiratory, urinary, nervous and musculoskeletal. A case is reported of atypical Kawasaki disease associated with acute renal failure and necrotizing myositis in the right gastrocnemius in a 10-year-old...
A Case of Acute Renal Failure Associated with Tsutsugamushi Disease
Jin Hee Hong, Jin Hee Oho, Jong Hyun Kim, Dae Kyun Kho
Clin Exp Pediatr. 2001;44(4):464-468.   Published online April 15, 2001
Tsutsugamushi disease is acute febrile illness, transmitted by Rickettsia tsutsugamushi. R. tsutusgamushi invade and proliferate in the endothelial cells of small blood vessels. Destruction of endothelial cells occurs from the proliferation of the organism and eventual disruption, and thus vascular rich organs must be carefully examined such as the kidney, lung, heart, liver. Recently we experienced a case of acute...
A Case of Acute Renal Failure Following Intravenous Immunoglobulin Therapy in a Child
Sung-Wook Park, Kyung-Yil Lee, Kyung-Yil Lee, Kye-Nam Yoon, Sang-Won Cha, Dong-Jun Lee, Ji-Whan Han, Kyung-Tai Whang
Clin Exp Pediatr. 2000;43(5):720-724.   Published online May 15, 2000
Intravenous immunoglobulin(IVIG) therapy is associated with a number of complications, including rare acute renal failure(ARF). Although the cause of IVIG-associated ARF is unknown, it may be related to the stabilizing agent used in IVIG preparations. ARF following IVIG infusion has not been previously described in children. We report a 4-year-old girl with Kawasaki disease who suffered from ARF following IVIG...
Original Article
Clinicial Observations of Oliguric Acute Renal Failure in Children
Sung-Soo Lee, Young-Mi Choi, Chong-Woo Bae, Sung-Ho Cha, Byoung-Soo Cho
Clin Exp Pediatr. 1999;42(10):1419-1425.   Published online October 15, 1999
Purposes : We studied the clinicial findings of oliguric acute renal failure(ARF) developed on admission or during treatment of other diseases. Methods : We performed a retrospective analysis of medical records of 118 patients with oliguric ARF who had been admitted to Kyunghee University Hospital since January 1988 to December 1997. Diagnostic criteria of oliguric ARF are serum creatinine>1.0mg/dl and urine...
Factors Associated with Renal Failure in Children with Primary Vesicoureteral Reflux
Kyung Mi Park, Kyung Hoon Paek, Jae Hong Min, Jung Su Kim, Il Soo Ha, Kwang Myung Kim, Hae Il Cheong, Hwang Choi, Yong Choi
Clin Exp Pediatr. 1999;42(7):959-965.   Published online July 15, 1999
Purpose : The pathophysiologic mechanisms and risk factors of renal functional deterioration are still controversial. We analyzed the factors associated with renal failure in children with primary vesicoureteral reflux. Methods : The medical records of 166 children who were diagnosed with primary vesicoureteral reflux from Jan. 1985 to Dec. 1996 in the Department of Pediatrics, Seoul National University Children's Hospital...
Short Term Effect of Recombinant Human Growth Hormone Therapy in Children with Chronic Renal Failure
Si-Whan Ko, Dong-Kyu Ji
Clin Exp Pediatr. 1998;41(9):1256-1261.   Published online September 15, 1998
Purpose : Growth retardation is one of the major side effects of chronic renal failure. In this study, the short-term growth promoting effect, effect on the chemical parameters, and probable side effects of growth hormone treatment to child patients with chronic renal failure were examined. Methods : The research sample was 5 child patients diagnosed with chronic renal failure and receiving...
Case Report
Rhabdomyolysis-induced Acute Renal Failure in a Child
Weon Sang Yun, Keun Mo Ki, Byung Ju Kim, Jae Sook Ma
Clin Exp Pediatr. 1998;41(5):707-710.   Published online May 15, 1998
Rhabdomyolysis has been reported as a cause of acute renal failure(ARF), and it can arise from traumatic and variable non-traumatic events. Rhabdomyolysis-induced ARF is very rare in children. We experienced a case of rhabdomyolysis-induced ARF in a 14-year-old boy who presented with generalized edema and oliguria following trauma, a compressed thigh by a cultivator. Laboratory tests showed marked elevation of muscle...
Original Article
Acute Renal Failure in Children : Underlying Disease and Management according to Age
Eun Joung Park, Joung Sim Kim, Jai Bok Yoo, Joung Sook Sul, Si Whan Koh, Phil Soo Oh, I Suk Kang, Moon Soo Park, Heung Jae Lee, Dong Kyoo Jin
Clin Exp Pediatr. 1998;41(5):654-662.   Published online May 15, 1998
Purpose : It has been stressed that age itself as well as multiple organ failure are important prognostic factors in acute renal failure(ARF) in children. This study was performed to find out the significance of age factor and underlying disease of ARF in children. Methods : We tried to review 58 pediatric ARF cases, retrospectively, in the pediatric intensive care unit(excluding...
Case Report
Acute Renal Failure(ARF) Associated with Yersinia Pseudotuberculosis Infection Diagnosed by Polymerase Chain Reaction
Hyung Gyu Park, Byung Moon Ahn, Eun Ryoung Kim, Il Soo Kim, Jae Jong Kim, Sung Ok Kang, Han Ho Park, Ki Jeong Kim
Clin Exp Pediatr. 1997;40(8):1162-1168.   Published online August 15, 1997
The clinical significance of Yersinia pseudotuberculosis(Y. pseudotuberculosis) has recently recognized in various part of the world because it can cause a wide range of clinical problems such as mesenteric lymphadenitis, septicemia, reactive arthritis, terminal ileitis, erythema nodosum and acute renal failure. we experienced a case of acute renal failure associated with Y. pseudotuberculosis infection. We applied a nested polymerase chain reaction method for rapid diagnosis...
Original Article
Myocardial Functions Estimated by Pulsed Doppler Echocardiography in Patientswith Chronic Renal Failure
Hyun June Huh, Byung Ho Choi, Myung Chul Hyun, Sang Bum Lee
Clin Exp Pediatr. 1996;39(12):1712-1728.   Published online December 15, 1996
Purpose : The objectives of this study were to estimate myocardial functions in patients with chronic renal failure by pulsed Doppler echocardiography, and investigate correlation between Doppler and disease parameters. Methods : We studied 13 patients with chronic renal failure whose creatinine clearance rate less than 25ml/min. Using pulsed Doppler echocardiography with curve following method, we measured peak velocity, mean velocity, velocity-time integral and peak...
The Effect of Recombinant Human Growth Hormone on the Growth in the Children with Chronic Renal Failure
Sei Won Yang, Young Choi
Clin Exp Pediatr. 1996;39(7):997-1004.   Published online July 15, 1996
Purpose : We observed the effect of three year-administration of recombinant human growth hormone(rhGH) on the growth in the children with chronic renal failure(CRF). Methods : Five prepubertal children(three boys and two girls) with CRF, who had been managed by conservative methods, were given rhGH(1 U/kg/week) for three years. Growth parameters, such as growth velocity, height standard deviation score(SDS), and predicted final adult height, obtained...
A Study of Radiocontrast Media Induced Nephrotoxicit
Chong Guk Lee, Jae Ho Cho, Se Wook Oh, Yong Won Park
Clin Exp Pediatr. 1996;39(4):503-511.   Published online April 15, 1996
Purpose : This study was aimed at determining whether tri-iodinated compounds with greater solubility and low osmolality, Na or meglumine ioxaglate(Hexabrix 320, Guerbet Lab., France) had deleterious effects on renal function after cardiac angiography for the evaluation of congenital heart disease(CHD) and determining whether correction of dehydration using iv hydration given before cardiac angiography were effective in prventing renal dysfunction. Methods...
Effect of Different Levels of the Dietary Protein on Long Term Prognosis of Experimental Renal Damage
Choon Haeng Lee, Sang Joo Han, Hong Jin Lee, Won Il Park, Kyung Ja Lee, Young Eui Park, Min Chul Lee, Tae Heon Yoon
Clin Exp Pediatr. 1993;36(6):820-829.   Published online June 15, 1993
We examined the effect of various levels of dietary protein on long term prognosis of Adriamycinephropathy of S-D rat, fed with high protein(30%), intermediately low(10%), and strictly low(5%) protein diet for 15 weeks 1) In rats fed with strictly low protein diets(5%), proteinuria and serum creatinine decreased and creatinine clearance and histological changes were relatively well preserved. But hypoproteinmia and weight...
Growth Promoting Effect of Recombinant methionyl-Growth Hormone in Children with Chronic Renal Failure
Heon Seok Han, Yong Choi, Hyung Ro Moon
Clin Exp Pediatr. 1992;35(10):1355-1360.   Published online October 15, 1992
The authors studied the growth-promoting effect of yeast-derived methionyl-hGH in short statured children with uremic chronic renal failure. The subjects were prepubertal chronic renal insufficient patients whose height standard deviation scores were below -2.0. Two boys and two girls participated in this study. Chronic renal insufficiency was the only cause for the short stature. HGH was given to the subjects in dose...
Acute Renal Failure Following Cardiac Surgery
Kang Yong Park, Yeon Ho Choi, Tae Sun Ha, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Joon Ryang Rho
Clin Exp Pediatr. 1992;35(9):1198-1209.   Published online September 15, 1992
A retrospective study of 452 patients who undertook cardiac surgery was performed to determine the pevalence, etiology, and clinical features of postoperative acute renal failure(ARF). The overall incidence of ARF following cardiac surgery was 4.65%(21/452). The incidence of ARF following open heart surgery(OHS) was 5.11%, and that following closed heart surgery was 2.50%. Preoperactive risk factors noted in the development...
Acquired Renal Cystic Disease in Childhood Chronic Renal Failure
Tae Sun Ha, Seong Hoon Ha, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Woo Sun Kim, Kim In One
Clin Exp Pediatr. 1992;35(8):1044-1050.   Published online August 15, 1992
The authors evaluated 19 childrenwith chronic renal failure patients diagnosed and followed up at the Department of Pediatrics, Seoul National University Hospital for the detection of acquired renal cystic disease (ARCD) with two radiologists by the means of ultrasonography. The results were as follows: 1) Of the 19 patients, male to femals ratio was 14:5 and of them, hemodialysis and peritoneal dialysis...
Acute renal failure with back pain after exercise.
Hae Jung Park, Mi Jung Kim, Dong Kyu Jin, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Jung Mi Park, Kyung Mo Yeun
Clin Exp Pediatr. 1991;34(6):863-868.   Published online June 30, 1991
We have experienced one case of acute renal failure without clinical rhabdomyolysis characterized by preceding exercise and back pain. This patient showed patch renal increased uptakes in bone scan with 99mTechnetium-methylene diphosphonate, and delayed wedge-shaped contrast enhancements in renal computed tomography. These findings can be explained by focal renal vasoconstriction of interlobar arteries or arcuate arteries, which may be considered as one of the...
Mannitol induced acute oliguric renal failure.
Young Mi Chung, Jae Seung Lee, Chang Jun Coe
Clin Exp Pediatr. 1991;34(6):857-862.   Published online June 30, 1991
Mannitol known as non-electrolytic, osmotic diuretic agent is widely used in clinic for the purpose of diagnosis and prevention of acute oliguric renal failure, cerebral edema as well as glaucoma and dialysis-disequilibrium syndrome. That mannitol may cause serious life-threatening situation if administered in a patient with renal problem has been well known. Recently, it has been published that mannitol may be nephrotoxic in patient...
A Case of Acute Interstitial Nephritis Associated with Yersinia Pseudotuberculosis Infection.
Keun Hee Chung, Yoo Mee Kim, Mee Won Kim, Soon Gi Kim, Moon Soo Park, Jin Keun Chang
Clin Exp Pediatr. 1990;33(8):1123-1128.   Published online August 31, 1990
Authors recently experienced a case of acute interstitial nephritis associated with Yersinia pseudotuberculosis infection in 10-8/12 year old boy, who was admitted to prolonged high fever. On 3rd hospital day, puffy face and oliguria were noted. BUN and serum creatinine rose to peak level, 94.1 mg/dl and 10.1 mg/dl, respectively on 7th hospital day. After then renal functions were normal- ized gradually without specific...
Recombinant Human Erythropoietin Therapy in Anemia Accompanied by Chronic Renal Failure.
Dong Kyu Jin, Hae Il Cheong, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1990;33(7):970-976.   Published online July 31, 1990
A clinical study was carried out to evaluate the efficacies of rHuEPO (recombinant human erythropoietin) in anemia of 7 chronic renal failure patients under dialysis at Seoul National University Children's Hospital from Feb. 1989 to Nov. 1989. The results were as follows; - 1) There was progressive increase of hematocrit levels in all 6 hemodialysis patients and mainte- nance dosage of rHuEPO to sustain hemoglobin...
Juvenile Nephronophyjisis in An Infant.
Young Seo Park, Chang Youn Lee, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Je Geun Chi, Chang Bin Im
Clin Exp Pediatr. 1989;32(8):1155-1160.   Published online August 31, 1989
Juvenile nephronophthisis is a chronic tubulo-interstitial renal disease characterized by an early onset of polyuria and polydipsia, decreased urinary concentrating ability, anemia, growth retardation and progressive renal disease. It is recognized as an important cause of chronic renal failure in the childhood. However only one case was reported in the Korean literatures. In this paper we have reported the second documented case of juvenile...
Continuous Arteriovenous Hemofiltration in Children.
Hae Il Cheong, Dong Kyu Jin, Young Seo park, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1989;32(2):230-238.   Published online February 28, 1989
Among those who were admitted to the Pediatric Intensive Care Unit (PICU), Seoul National University Children’s Hospital and developed acute renal failure (ARF) during the disease course, 11 children received continuous arteriovenous hemofiltration (CAVH) by pediatricians during a 3-year- period from Nov. 85 to Oct. 88. Their clinical findings were analyzed retrospectively, and the results were as follows; 1) They were 5 boys and 6...