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Review Article
Neurology
Rotavirus infection-associated central nervous system complications: clinicoradiological features and potential mechanisms
Kyung Yeon Lee
Clin Exp Pediatr. 2022;65(10):483-493.   Published online February 7, 2022
∙ Rotavirus infection-associated central nervous system (CNS) complications are fairly common in children.
∙ Common clinicoradiological features include benign convulsions with mild gastroenteritis, acute encephalopathies/encephalitis, cerebellitis, and neonatal rotavirus-associated leukoencephalopathy.
∙ Possible mechanisms for CNS complications include direct viral invasion into the brain via several potential routes such as the blood-brain barrier and vagus nerve, and entry of various brain-damaging mediators and activated immune cells into the brain.
Original Article
Cardiology
Early myocardial functional abnormalities in primary dyslipidemia: clinical and echocardiographic observations in young children from a highly consanguineous population
Nehal M. El-koofy, Aya M. Fattouh, Areef Ramadan, Mohamed A. Elmonem, Dina H. Hamed
Clin Exp Pediatr. 2022;65(8):410-416.   Published online December 8, 2021
In children with primary dyslipidemia, functional myocardial abnormalities can occur at young age, including diastolic functional impairment of both ventricles and narrowing of the aortic valve and the sinus of Valsalva. Echocardiographic evaluations of high-risk children may be as important as biochemical evaluations.
Nutrition
Impact of preoperative nutritional status on surgical outcomes in patients with pediatric gastrointestinal surgery
Nehal El Koofy, Hadeer Mohamed Nasr Eldin, Wesam Mohamed, Mostafa Gad, Sara Tarek, Gamal El Tagy
Clin Exp Pediatr. 2021;64(9):473-479.   Published online November 16, 2020
Question: Is malnutrition a risk factor for postoperative complications in pediatric surgical patients?
Finding: There is a high incidence of malnutrition in pediatric surgical patients. Stunting increases the risks of postoperative complications and extended hospital stays, while underweight status contributes to extended hospital stays.
Meaning: Preoperative nutritional assessments are crucial to improving postoperative outcomes. Anemia increases the risk of postoperative complications and should be corrected preoperatively.
Case Report
Hepatic glycogenosis in type 1 diabetes mellitus mimicking Mauriac syndrome
In Ah Jung, Won Kyoung Cho, Yeon Jin Jeon, Shin Hee Kim, Kyoung Soon Cho, So Hyun Park, Min Ho Jung, Byung-Kyu Suh
Clin Exp Pediatr. 2015;58(6):234-237.   Published online June 22, 2015

Hepatic glycogenosis in type 1 diabetes mellitus (DM) can be caused by poor glycemic control due to insulin deficiency, excessive insulin treatment for diabetic ketoacidosis, or excessive glucose administration to control hypoglycemia. Mauriac syndrome, which is characterized by hepatomegaly due to hepatic glycogenosis, growth retardation, delayed puberty, and Cushingoid features, is a rare diabetic complication. We report a case of...

Lung torsion after tracheoesophageal fistula repair in an infant
Eun Mi Yang, Eun Song Song, Hae in Jang, In Seok Jeong, Young Youn Choi
Clin Exp Pediatr. 2013;56(4):186-190.   Published online April 22, 2013

Lung torsion is a very rare event that has been reported in only 9 cases in the pediatric literature but has not yet been reported in Korean infants. We present a case of lung torsion after tracheoesophageal fistula repair in an infant. Bloody secretion from the endotracheal tube and chest radiographs and computed tomographic scan results indicated lung torsion. Emergency...

Original Article
Clinical features and surgical outcomes of complete transposition of the great arteries
Suk Jin Hong, Hee Joung Choi, Yeo Hyang Kim, Myung Chul Hyun, Sang Bum Lee, Joon Yong Cho
Clin Exp Pediatr. 2012;55(10):377-382.   Published online October 29, 2012
Purpose

This single-center study aimed to assess the clinical features and surgical approaches and outcomes of complete transposition of the great arteries (TGA).

Methods

TGA patients who had undergone surgical correction at the Kyungpook National University Hospital from January 2000 to December 2010, were retrospectively evaluated for patient characteristics, clinical manifestation, preoperative management, intraoperative findings, postoperative progress, and follow-up status.

Results

Twenty-eight patients (17 boys...

Review Article
Complications of nephrotic syndrome
Se Jin Park, Jae Il Shin
Clin Exp Pediatr. 2011;54(8):322-328.   Published online August 31, 2011

Nephrotic syndrome (NS) is one of the most common glomerular diseases that affect children. Renal histology reveals the presence of minimal change nephrotic syndrome (MCNS) in more than 80% of these patients. Most patients with MCNS have favorable outcomes without complications. However, a few of these children have lesions of focal segmental glomerulosclerosis, suffer from severe and prolonged proteinuria, and...

Original Article
A case of meningoencephalitis caused by Listeria monocytogenes in a healthy child
Ji Eun Lee, Won Kyoung Cho, Chan Hee Nam, Min Ho Jung, Jin Han Kang, Byung Kyu Suh
Clin Exp Pediatr. 2010;53(5):653-656.   Published online May 31, 2010

Listeria monocytogenes is a facultative anaerobic, gram-positive bacillus that is isolated from the soil, vegetables, and wild or domestic animals. Listeria occurs predominantly in the elderly, immunocompromised patients, pregnant women and newborns. Infections by this microorganism are rare in healthy infants and children. L. monocytogenes may cause meningitis, meningoencephalitis, brain abscess, pyogenic arthritis, osteomyelitis, and liver abscesses in children. The...

Review Article
Cardiovascular complications after Kawasaki disease and its management
Gi Young Jang
Clin Exp Pediatr. 2008;51(5):462-467.   Published online May 15, 2008
Kawasaki disease is a systemic vasculitis of unknown etiology, usually occurring in infants and young children. Although the etiology of Kawasaki disease remains uncertain, its serious complicationssuch as giant aneurysm formation, coronary arterial stenotic lesions, and thrombotic occlusionhave been proven to cause myocardial ischemia or infarction in patients with Kawasaki disease. To prevent and treat these complications, several modes of...
Original Article
Complications of transcatheter closure of atrial septal defects using the amplatzer septal occluder
Seo Jin Jea, Hyo Jin Kwon, Gi Young Jang, Jae Young Lee, Soo Jin Kim, Chang Sung Son, Joo Won Lee
Clin Exp Pediatr. 2008;51(4):401-408.   Published online April 15, 2008
Purpose : Transcatheter closure of atrial septal defects (ASD) is currently established therapy as an alternative to surgery. But rarely, complications are reported in some studies. We report early and intermediate term complications associated with transcatheter closure of atrial septal defects using the Amplatzer septal occluder (ASO). Methods : From June 2003 to May 2006, 64 patients underwent transcatheter closure of...
Review Article
Characteristics of allergic pollens and the recent increase of sensitization rate to weed pollen in childhood in Korea
Jae-Won Oh
Clin Exp Pediatr. 2008;51(4):355-361.   Published online April 15, 2008
Pollen is very important causing factor for allergy such as allergic rhinitis, allergic conjunctivitis, and asthma, and pollen allergy has a remarkable clinical impact all over Korea. The main pollination period covers about half the year, from spring to autumn, and the distribution of airborne pollen taxa of allergological interest is related to pollen season dynamics. Korean academy of pediatric...
Case Report
Two cases of postoperative chylothorax treated with parenteral octreotide and conservative therapy
Eun Jin Choi, Sub Lee
Clin Exp Pediatr. 2007;50(3):298-301.   Published online March 15, 2007
Chylothorax is a rare complication following cardiac surgery for congenital heart diseases. Although conservative management is successful in the majority of cases, surgical intervention is required in a refractory one. Recently, subcutaneous or intravenous infusion of octreotide has been used as a safe treatment that helps avoiding surgical intervention. Herein, we report two cases of postoperative chylothorax treated with parenteral...
Original Article
A study and the growth and the development of microvascular complications in patients with type 1 diabetes mellitus
Young Ah Lee, Kyong-Ah Yun, Choong Ho Shin, Sei Won Yang
Clin Exp Pediatr. 2007;50(2):190-197.   Published online February 15, 2007
Purpose : Reduced growth and microvascular complications have been recognized as consequences of type 1 diabetes mellitus (T1DM). We assessed the effect of T1DM on growth and factors associated with the development of microvascular complications. Methods : We conducted a retrospective longitudinal evaluation of 154 patients above 16 years of age. We analyzed factors which affect final height standard deviation scores...
Clinical Significance of C-reactive Protein in Measles
Sang-Lim Choi, Kyung-Yil Lee, Hyung-Shin Lee, Ja-Hyun Hong, Kyung-Tai Whang
Clin Exp Pediatr. 2003;46(5):480-483.   Published online May 15, 2003
Purpose : We evaluated clinical manifestations and laboratory findings in patients with measles according to C-reactive protein(CRP) concentration. Methods : A retrospective analysis was performed using the medical records of patients with measles at The Catholic University of Korea, Daejeon St. Mary's Hospital from October 1999 to May 2000. We divided the patients with measles into four groups according to CRP...
Case Report
A Case of Polio-like Encephalomyelitis Associated with Enterovirus 71 Infection
Hyun Kyung Roh, Hee Jung Chung, Young Mee Jee, Doo Sung Cheon
Clin Exp Pediatr. 2001;44(11):1305-1310.   Published online November 15, 2001
Enterovirus 71(EV71), like polioviruses, invades the central nervous system to give rise to aseptic meningitis, encephalitis or myelitis. EV71 was first isolated in California in 1969 from a 9-month- old infant with encephalitis. Since then it has been isolated from the brain of children who died of encephalitis and from feces of patients with meningitis, encephalitis or paralysis. Related strains...
Original Article
Factors Related to the Development of Microalbuminuria in Children and Adolescents with Type 1 Diabetes Mellitus
Min Ho Jung, Pei Tai Wan, Choong Ho Shin, Sei Won Yang
Clin Exp Pediatr. 2001;44(5):577-586.   Published online May 15, 2001
Purpose : We observed the prevalence rate of microalbuminuria(MA) and its relationship with the various clinical factors in children and adolescents with type 1 diabetes mellitus(DM). Methods : Seventy two children and adolescents(26 males and 46 females, 17.1±3.0 years) were included. MA was defined as 24 hour urine microalbumin >30mg/day(20μg/min). Subjects were classified into three groups(normoalbuminuria, transient MA, or persistent MA)....
The Perinatal Complications in Infants of Mothers with Gestational Diabetes Mellitus
Ju Yeon Yeo, Seong Won Yang, Hye Kyung Han, Mi Ryung Um, Woo Gill Lee, Mi Na Lee, Hak Chul Jang, Ho Yeon Jung, Eun Sung Kim, Kyu Byung Jung
Clin Exp Pediatr. 1997;40(6):809-917.   Published online June 15, 1997
Purpose : This study was performed to examine the impact of gestational diabetes mellitus (GDM) on perinatal outcomes, especially macrosomia and metabolic complications in Korean women. Methods : We studied perinatal outcomes of 65 women with GDM who delivered a singleton infant and were not complicated by medical disease that might effect the fetal growth, 65 women with normal glucose tolerance were selected to match subject...
Clinical Study of Hickman Catheters in Pediatric Oncologic Patient
Young-Ho Lee
Clin Exp Pediatr. 1996;39(5):682-690.   Published online May 15, 1996
Purpose : We performed a retrospective study to evaluate the complications from Hickman catheters in pediatric oncologic patients. Methods : Between October 1992 and July 1995, 27 Hickman catheters placed in 25 patients who were chemotherapy candidates were evaluated. The frequency and etiologic organisms of catheter infections, mechanical complications, and any problems that might have been related to catheter use were determined. Results : 1) The...
Incidence and Complications of Obesity in Pubescent School Children
Boo Hyun Han, Duk Hi Kim, Yoo Kyung Park, Jong Ho Lee, Ho Seong Kim
Clin Exp Pediatr. 1995;38(4):520-528.   Published online April 15, 1995
Purpose : In recent years, obesity in children has become one of the major nutritional problems, and the trend is that number of obese children is increasing. The purpose of this research is to examine the incidence of obesity in pubescent school children in Seoul and Cheju, and to analyze body fat component, complications and eating habits of those obese...
Neurologic Complications after Open-Heart Surgery in Children
Tae Sung Ko, Ki Joong Kim, Dong Wook Kim, Yong Seung Hwang, Yong Jin Kim, Joon Ryang Rho
Clin Exp Pediatr. 1993;36(9):1245-1257.   Published online September 15, 1993
Neurologic complications after open-heart surgery are not only relatively common but also often fatal. In order to know the clinical characteristics and carsative risk factors, we carried out the retrospective study on 655 patients who had been admitted and undergone OHS at Seoul National University Children's Hospital during 2-year period from July 1990 to June 1992. The results...