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Original Article
A Study for Causes of Death in Korean Children
Ha Baik Lee, Jun Hee Sul, Young Yull Koh, Jong Wan Kim, Young Jin Hong, Nam Su Kim, Myung Ik Lee
Clin Exp Pediatr. 1998;41(8):1047-1059.   Published online August 15, 1998
Purpose : Analyzing of the causes of childhood death will provide us with the basis to understand prevalent diseases and to make the best possible health plan according to the studies. The National Statistical Office(NSO) of Korea has released an annual report of nationwide death. However, it could have underestimated the death toll of children because of delayed or missing...
Expression of Tumor Suppression Gene in Childhood Cancer
Ji Eun Lee, Myung Ik Lee, Chang Soo Park
Clin Exp Pediatr. 1998;41(3):383-389.   Published online March 15, 1998
Purpose : Childhood cancer is closely related to the mutation of tumor suppressor gene. The mutant gene may evoke congenital anomaly and development of cancer. The common solid tumors in childhood are Wilms' tumor, retinoblastoma and neuroblastoma. The cytogenetic study has been performed. The cytogentic study revealed structural abnormality of chromosome in Wilms' tumor and retinoblastoma. The oncogene and mutation...
Observation of Social Background and Disease Patterns of Children in an Institute for Adoption (the 3rd report)
Jae Bong Kwon, Cheol Soon Park, Jae Wook Ko, Myung Ik Lee, Don Hee Ahn
Clin Exp Pediatr. 1995;38(1):81-90.   Published online January 15, 1995
Purpose : A Study was undertaken to assess the family background of abandonment and clinical and social aspects in an institute for foreign adoption. The results were compared to the previous two reports from the institute. Method : A sample of 1,728 children from 1987 to 1992 formed the subjects of the study by the medical records in the institution. Results :...
A Clinical and Pathological Study of Recurrent Hematuria in Childhood
Mi Jeong Kim, Jae Wook Ko, Young Jin Hong, Myung Ik Lee, Sun Wha Kim, Don Hee Ahn
Clin Exp Pediatr. 1994;37(8):1104-1110.   Published online August 15, 1994
The clinico-pathological observation was done on 28 children with recurrent hematuria, who had been admitted to the Pediatric ward of NMC from January 1981 to July 1991. The results were as follows; 1) Most of the children with recurrent hematuria were over 6 years of age (24 cases, 85.7%) and the sex ratio was about 2.5:1. 2) IgA nephropathy (17 cases, 60.7%) was...
Case Report
A Case of Subcutaneous Fat Necrosis Of the Newborn
Hong Shin Jeon, Myung Ik Lee, Don Hee Ahn, Hee Jun Yoo
Clin Exp Pediatr. 1994;37(3):405-409.   Published online March 15, 1994
A 7 day old female baby suffered from perinatal asphyxia and trauma at birth. Subsequently, she had a violeceous subcutaneous plaque on back. The clinical setting, the skin manifestation and the histologic findings of the lesion were diagnostic of subcutaneous fat necrosis of the newborn. Histologic findings revealed fat necrosis with infiltration of inflammatory cells, foreign body giant cells and...
Original Article
Clinical Studies of Salmonelosis in Childhood
Hong Shin Jeon, Young Jin Hong, Myung Ik Lee, Keun Chan Sohn
Clin Exp Pediatr. 1994;37(2):199-204.   Published online February 15, 1994
During The last 11 years from Jan. 1980 to Dec. 1990, 72 cases of salmonellosis has been admitted to the Department of Pediatrics of National Medical Center and evaluated clinical difference between typhoid fever and salmonella gastroenteritis. The result were as follows: 1) The annual incidence of salmonella gastroenteritis in salmonellosis was increased in the latter half of the eighties. 2) Both...
A Clinical Study on Prematurity Who received Blood Transfusion
Chul Soon Park, Myung Ik Lee, Soon Wha Kim, Don Hee Ahn
Clin Exp Pediatr. 1993;36(10):1389-1394.   Published online October 15, 1993
A clinical study was made on 85 cases of prematurity under 37 weeks of gestational age who had history of blood transfusion during their admission at the National Medical Center from January 1989 to June 1992. The results were as follows: 1) Among 339 prematurity patients, 85 patients (25.1%) received blood transfusion once at least. 2) Male to female ration was 1.13:1 and...
Cow Milk Allergy in Infant Who Neonatal Onset
Seung Hee Park, Myung Ik Lee, Don Hee Ahn, Seung Hee Park
Clin Exp Pediatr. 1993;36(10):1383-1388.   Published online October 15, 1993
Cow milk allergy can be defined as an adverse immunologic reactions to cow milk protein. The term is often mistakenly applied to other causes of milk intolerence, such as lactase deficiency and galactosemia, which must be differenciated and excluded. We have experienced 10 children of cow milk allergy at neonatal onset who had suffered from G-I symtons, such as diarrhea, irritability,...
A Clinical Study of Bronchial Asthma in Children
Seung Hee Park, Myung Ik Lee, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1993;36(9):1291-1299.   Published online September 15, 1993
This report is a clinical analysis and comparative study with previous report of bronchial asthma at National Medical Center on bronchial asthma in children who were admitted to the MP dept. of national Medical Center from January 1987 to December 1990. The results of the study were as follows: 1) The out-break ratio of bronchial asthma is 3.7% of hopitalized children which...
Case Report
A Case of Kugelberg-Welander Syndrome
Sun Young Lee, Myung Ik Lee, Soon Wha Kim, Don Hee Ahn, Je Geun Chi
Clin Exp Pediatr. 1992;35(9):1263-1266.   Published online September 15, 1992
We have experienced a 6 year-old female patient who had suffered from progressive muscular atrophy with weakness and loss of voluntary motor action since 3 years of age. She was diagnosed as Kugelberg-Welander syndrome by EMG and muscle bio. Multiple polyphasic motor unit potentials were revealed on EMG and grouped muscle atrophy without fibrosis or degenerative change was found on...
Seven Cases of Immotile Cilia Syndrome
Sun Young Lee, Myung Ik Lee, Don Hee Ahn, Keun Chan Sohn, Je Geun Chi
Clin Exp Pediatr. 1992;35(8):1127-1134.   Published online August 15, 1992
Immotile cilia syndrome is a disease caused by congenital abnormality of the cilia and symptom complex composed by chronic rhinitis, sinusitis, otitis, male infertility etc. We have experienced 7 cases of immotile cilia syndrome diagnosed by electron microscopic finding of nasal or bronchial mucosal biopsies since 1984. Six cases were girls and type Id was most common (4 cases) on...
Original Article
Clinical Observation on Reye syndrome According to the Onset of Age in Children
Kyung Hee Kim, Baik Hee Lee, Myung Ik Lee, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1992;35(6):788-794.   Published online June 15, 1992
A clinical observation according to the age of onset was made on 40 children with Reye syndrome who had been admitted to pediatric department of National Medical Center during 11 year period from January 1979 to December 1989. 1) Annual distribution showed the largest number in 1982. There was no significant difference in seasonal distribution. 2) Cases of infant comprised 22 (55.0%)...
Polymicrobial Bacteremia in Children
Hyun Seung Park, Myung Ik Lee, Soon Wha Kim, Don Hee Ahn
Clin Exp Pediatr. 1992;35(4):499-507.   Published online April 15, 1992
A clinical observation was made on 212 cases of bacteremia in children, who were hospitalized at department of pediatrics, National Medical Center from Jan. 1981 to Dec.1988 The results were as follows; 1) Blood culture proven bacteremia were 212 cases in children. Among them polymicrobial bacteremia were 22 cases(10.4%) and monomicrobial bacteremia were 190 cases(89.6%). The same species of bacteria was cultured...
Clinical Observation on Newborn using Artificial Ventilator
Hyun Seung Park, Myung Ik Lee, Soon Wha Kim, Don Hee Ahn
Clin Exp Pediatr. 1992;35(3):322-329.   Published online March 15, 1992
Retrospective clinical analysis of 5 and a half yeas experience with artificial ventilaion on 187 neonas in NICU of National Medical Center, from Jan. 1985 to Dec. 1990, was done. The results were as follows; 1) Number of patients, who required respiratory therapy with aritificial ventilation, was 187 and the percentage of these patients to all hospitalized neonates was 11.4%. 2) Number...
Prevalence of hepatitis B surface antigen in pediatric in patients.
Kyung Hee Kim, Myung Ik Lee, Young Jin Hong, Keun Chan Sohn
Clin Exp Pediatr. 1991;34(3):355-362.   Published online March 31, 1991
Thirty three from 689 children (4.79%) who were screened among hospitalized patients from July, 1986 to June, 1988, were positive for hepatitis B surface antigen in their serum sample tested by radioimmunoassay. The positive rate of hepatitis B surface antigen was 3.04% when the hepatitis patients were excluded. The incidence of hepatitis B surface antigen was higher (5.18%) in male than in famale (4.17%)...
Role of aldosterone on the minimal change nephrotic syndrome in children.
Soon Wha Kim, Myung Ik Lee, Don Hee Ahn
Clin Exp Pediatr. 1989;32(11):1526-1532.   Published online November 30, 1989
We studied 11 cases of minimal change nephrotic syndrome randomly selected among 16 cases of minimal change nephrotic syndrome who were proved by kidney biopsy at department of pediatrics, National Medical Center during the period of January 1985 through December 1987. These patients were studied serially at 3 different stages in their clinical course. These were stages of edema formation, diuresis and remission, respectively. The...
Clinical Study of Interrelationship Between Cold Agglutinin Titers and Indirect Hemagglutination Titers in Children with Mycoplasma Pneumoniae Pneumonia During Recent 3 Years.
Jong Chan Shin, Jae Youn Kim, Myung Ik Lee, Soon Wha Kim, Keun Chan Sohn, Kyeung Eun Jung
Clin Exp Pediatr. 1989;32(7):915-925.   Published online July 31, 1989
A clinical study was made on 103 cases of Mycoplasma pneumoniae pneumonia patients during the period of 3 years from July ’84 to June '87. Indirect hemagglutination test (IHA) and/or cold agglutinin test (CAT) were measured and follow-up studies were done until the 50th day of the illness. Each titer was compared for analysis of interrelationship between them. And we obtained following results: 1) The highest...
Study on the Clinical Aspect of Failure to Thrive.
Hyung Keun Nam, Myung Ik Lee, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1989;32(3):303-310.   Published online March 31, 1989
Failure to thrive means infants and children whose growth and often development are significantly below expected stanards, usually below the third percentile. It is relatively apt to develop during the first 2 years of life. The clinical observations were made on 79 patients of failure to thrive who were diagnosed at pediatric dept., National Medical Center from January, 1981 to June, 1986. The results were...
Clinical Observations of Meningitis.
Byoung Hoon Lee, Hyung Keun Nam, Myung Ik Lee, Keun Chan Sohn
Clin Exp Pediatr. 1989;32(2):180-190.   Published online February 28, 1989
The 267 cases of meningitis were observed at National Medical Center between Jan. 1st 1979 and May 31, 1986. The results were as follow; 1) In BM and TM sexual difference was not notice, but male was more in AM. 2) In BM infancy was the most common, but school age was common was AM. 3) Most cases developed during spring in BM and TM...
Observation of Socail Background and Diesase Petterns of Children in an Institute for Adoption (the 2nd report).
Hong Hoon Lee, Myung Ik Lee, Soon Wha Kim, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1988;31(9):1171-1182.   Published online September 30, 1988
A study was made to see the family background of abandonment and clinical and laboratory findings in an institute for foreign adoption. The results were compared to the previous report from the same institute. The results were as follows. 1) Girls were much more than boys in number with male to female ratio of 1:2.1 2) Concerning age distribution, the infant under one month of age was...
A Clinical and Allergological Study on Sinusitis in Children.
Jung Kyung Kim, Myung Ik Lee, Soon Wha Kim, Keun Chan Sohn
Clin Exp Pediatr. 1987;30(11):1236-1242.   Published online November 30, 1987
Sinusitis, despite of common in childhood, is still somewhat difficult proiblem to pediatrician in diagnosis and its complication, and plays a role of known one of trigerring factors in asthma. A clinical and allergological evaluation was performed on 235 cases, who were taken paranasal sinus X-ray at N.M.C. Pediatric OPD and in the ward from January 1985 to May 1986. The results were as...
A Survey of the Outcome of Childhood Asthma.
Hyung Ja Park, Myung Ik Lee, Sun Wha Kim, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1987;30(1):55-63.   Published online January 31, 1987
An outcome of 416 children who was diagnosed and treated for bronchial asthma at pediatric department of National Medical Center from 1965 to 1984 was surveyed using return postcard. The following results were obtained. 1) We mailed 416 cards and 74 cards (17.8%) were returned. 2) 37.8% of the patients had been entirely asymptomatic for a year or more and 32.5% improved. 22.9% of the patients...
A Comparative Study on Serum Ferritin Concentrations in Anemic Patients Various Diseases.
Sei Woo Chung, Myung Ik Lee, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1986;29(7):730-739.   Published online July 31, 1986
Ferritin is a high-molecular weight iron compound consisting of a protein shell, which has normally been considered as a storage compound from which iron is readily mobilized either into the transferrin-bound plasma pool or for intracellular heme synthesis. For comparison of serum ferritin concentrations in anemic patients of various diseases, we measured serum ferritin concentrations, serum iron concentrations, total iron...
Case Report
A case of Congenital Factor X III Deficiency.
Sei Woo Chung, Myung Ik Lee, Don Hee Ahn, Keun Chan Sohn, Jin Sook Hong, Dong Hun Yoon
Clin Exp Pediatr. 1986;29(5):553-559.   Published online May 31, 1986
A 4 year and 7 month old male patient was admitted with the chief complaint of subgaleal hematoma and recurrent bleeding episodes. The first episode was umbilical cord bleeding on the third day of life. Routine coagulation study including factor assay at that time was within normal limit. The bleeding cleared after whole blood transfusion. He had been admitted...