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Original Article
A Clinical Study on Infants of Diabetic Mothers
Gyeong Choe, Young Kwon Choi, Young Youn Choi, Tai Ju Hwang
Clin Exp Pediatr. 1993;36(10):1407-1416.   Published online October 15, 1993
Thirty one infants of diabetic mothers(IDM) who had been admitted in Neonatal Intensive Care Unit at Chonnam University Hospital from January 1987 to July 1991 were studied for evaluation of their perinatal outcome and prognosis. The results were as follws; 1) The distribution of diabetic mothers according to modified White뭩 classification was GD & class A in 12 cases (38.7%), B in...
Comparison of Tuberculin Skin Test Results and Adberse Reactions Following BCG Vaccination In Various Infant Groups of Different Ages
In Seung Park, Dong Ki Han, Ho Joon Lim, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 1993;36(9):1300-1307.   Published online September 15, 1993
Most authorities including WHO recommended immununizing infants with BCG as early as possible in areas prevalent with tuberculosis, however the optimal time for immunization has not well been characterized. Therefore the investigation was undertaken by vaccinating various infant groups of different ages with BCG and subsequently evaluating for adverse effects and tuberculin reactions, in order to contribute to undestanding the...
Clinical Observation for Low Birth Weight Infants
Hye Jin Lee, Soon Wan Kwon, Soon Ok Byun, Ji Sub Oh
Clin Exp Pediatr. 1993;36(7):928-935.   Published online July 15, 1993
Clinical observations were made on 338 low birth weight infants, who were delivered at Pusan Wallace Memorial Baptist Hospital, during the 3 year periods from 1989 to 1991. The results were as follows; 1) The incidence of LBWI was 5.6% and sex ratio was 1:1.09. Among them AGA was 62.7%. 2) Of all infants, 47.3% were in the birth weight range of 2251-2500...
Clinical Study on Infants of Diabetic Mothers
Eun Eui Kim, Min Jeong Kim, Yang Sook Choi, Son Sang Seo
Clin Exp Pediatr. 1993;36(3):347-355.   Published online March 15, 1993
A clinical observation was performed on the 80 cases of neonates born from diabetic mothers among the total of 34,936 neonates delivered at Il Sin Christian Hospital from January 1985 to December 1989. The results were as follows : 1) The incidence of infants of diabetic mothers was 0.23%, among whom gestational diabetic mothers were 63 cases(78.7%) and overt diabetic mothers...
Neurosonographic Diagnosis of Periventricular-Intaventricular Hemorrhage in Low Birth Weiht Infants
Hee Seok Koh, Dong Kyun Ryu, Young Tack Jang, Oh Kyung Lee, Jin Ok Choi
Clin Exp Pediatr. 1993;36(1):57-66.   Published online January 15, 1993
Periventricular-intraventricular hemorrhage (PV-IVH) is one of the most important neurologic lesion of the low birth weight infants. Serial neurosonographic examinations were performed in 113 low birth weight infants who were admitted to the neonatal internsive care unit of Presbyterian Medical Center from November 1, 1990 to July 31, 1991. The results were summarized as follows: 1) The incidence of PV-IVH in he study...
Evaluation of the Development of High Risk Low Birth Weight Infants Using Bayley Developmental Test
Chul Lee, Yil Seob Lee, Hyung Rae Cho, Dong Kwan Han
Clin Exp Pediatr. 1993;36(1):38-48.   Published online January 15, 1993
Forty two high risk low birth weight infants who had been admitted in neonatal intensive care unit at Yongdong Severance Hospital from August 1987 to July 1990 and followed up in the high risk infants follow-up clinic were studied for evaluation of their development using the Bayley developmental test at the age of 9 month (corrected age). The results obtained were...
Statistical Study on the Incidence and Mortality Rate of Low Birth Weight Infant
Sun-ae Kang, Jae-Kag Choi, Yeon-Kyun Oh
Clin Exp Pediatr. 1992;35(12):1690-1695.   Published online December 15, 1992
A statistical study on the icidence and mortality rate of low birth weight infant (LBW) was done on 11,406 newborns delivered at Wonkwang University Hospital during 9 years from Jan. 1,983 to Dec. 1,991. The results were as follows, 1) The incidence of LBW was 10.2%. 2) The incidence of LBW was higher than that of other hospital delivery (p<0.005). 3) Mortality rate of...
The Relationship Between Neonatal Hypoglycemia and Newborn Iron Status in Hypoglycemic Large-for-Gestational Age Infants
Myung Ja Yun, In Ho Song, Hye Lim Jung, Dong Hyuck Kum
Clin Exp Pediatr. 1992;35(12):1667-1673.   Published online December 15, 1992
We assessed the relationship between neonatal hypoglycemia and newborn iron status in hypoglycemic large-for-gestational age, euglycemic large for gestational age and euglycemic appropriate for gestational age infants that were admitted to the department of Pediatrics, Koryo General Hospital from July 1989 to June 1990. The results are as follows; 1) The incidence of large for gestational age infants was 3.3% (32...
Case Report
A Case of Early Infantile Epileptic Encephalopathy
Sang Mi Ha, Hee Jung Jung
Clin Exp Pediatr. 1992;35(11):1590-1596.   Published online November 15, 1992
Early infantile epileptic encephalopathy is characterized by its early onset (less than 3 months of age), frequent tonic spasms, suppression-burst on EEG, extremely poor response to treatment and grave outcome. The authors experienced a case of early infantile epileptic encephalopathy. The patient was a 1-month-old girl with a complaint of generalized tonic convulsion since 2 days of age, and her EEG...
Original Article
Children with Delayed Speech Development
Sang Kee Park, Ho Sung Yoo, Yeong Bong Park
Clin Exp Pediatr. 1992;35(9):1236-1242.   Published online September 15, 1992
The antioxidant enzymes superoxide dismutase, catalase and glutathione peroxidase and the lipid peroxidation were assayed in erythroctyes from the cord blood of 25 fullterm newborn infants and their maternal blood abtained immediatedly after normal delivery. Superoxide dismutase and catalase activites in cor blood erythroctytes were significantly lower when compared with their mothers, but glutathione peroxidase activities were not significantly lower....
Infantile Asthma and Egg Allergy
Sung Hee Lim, Hye Sun Lee, Young Min Ahn
Clin Exp Pediatr. 1992;35(9):1226-1235.   Published online September 15, 1992
Egg is known to be the most common food allergen, which induces various symptoms such as atopic dermatitis, bronchial asthma, urticaria, angioedema, gastrointestinal symproms & anaphylaxis, especially during infancy. To evaluate the clinical course & significance of egg allergy in infantile asthma, we performed diagnostic study on 44 patients who were diagnosed as infantile asthma in our hospital from 1988 to...
Case Report
Transfusion-Acquired Cytomegalovirus Infections in Two Premature Infants
Dong Wook Kim, Kyung Un No, Mi Jung Kim, Soon Mee Park, Hee Sup Kim, Young Pyo Chang, Hoan Jong Lee, Jung-Hwan Choi, Chong Ku Yun, Je Geun Chi
Clin Exp Pediatr. 1992;35(8):1141-1147.   Published online August 15, 1992
Transfusion-acquired perinatal cytomegalovirus (CMV) infection can cause significant morbidity and mortality, particularly in premature infants with a birth wight of less than 1,500 gm. This recognizable syndrome consisted of deterioration of respiratory function, hepatosplenogaly, unusual gray pallor with disturbing septic appearance, lymphocytosis, thrombocytopenia and hemolytic anemia. We experienced transfusion-acquired CMV infections in 2 premature infants with a birth weight of...
A Case of Necrotizing Enterocolitis Associated with Cow and Soy Milk Intolerance
Sang Soo Roh, Young Il Park, Sang Il Lee
Clin Exp Pediatr. 1992;35(6):862-866.   Published online June 15, 1992
A case of necrotizing enterocolitis was associated with cow and soy milk intolerance in a term infant. The infant developed symptoms and radiologic findings-pneumatosis intestinalis and portal vein gas-after ingestion of cow and soy milk. Vomiting and diarrhea recurred with reintroduction of either cow or soy milk several times. The infant remained asymptomatic with a good growth rate on breast...
An Autopsy Case of Infant of Diabetic Mother with d-Transposition of Great Arteries and Hypertrophic Cardiomyopathy
Kye Hwan Seol, Eui Kyeung Jung, Chang Sung Son, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 1992;35(4):545-550.   Published online April 15, 1992
Generally, infants of diabetic mother(IDM) have various diseases and complications affecting multisystems resulting in high perinatal morbidity and mortality. It is well known that IDM have especially higher incidence of congenital anomalies including congenital heart disease(CH D). dTransposition of great arteries(d-TGA), ventricular septal defect and hypertrophic cardiomyopathy(HCM) form most of CHD occurring in IDM. Of these, HCM appears as a...
Original Article
A Clinical Study on Infantile Spasms with ACTH Therapy
Se Hee Hwang, Yong Seung Hwang
Clin Exp Pediatr. 1992;35(4):459-469.   Published online April 15, 1992
Infantile spasms is a disease, causes or treatments of which are not clearly delineated. Pri-mary objectives of treatment are complete control of seizure attack and prevention of further brain damage. Forty-one patients were managed with ACTH, who were diagnosed as infantile spasms and admitted to the Department of Pediatrics, Seoul National University Hospital from July 1985 till June 1990. The results...
Effucact of Adenosine Triphosphate in Infants and Children with Supraventricular Tachycardia
Yae Kyung Suh, Chung Il Noh
Clin Exp Pediatr. 1992;35(3):355-363.   Published online March 15, 1992
Acute tachyarrhythmia in infancy and childhood may be life-threatening if it is not treated promptly and accurately. The selection of a safe and effective pharmacologic agent is work in hand. We tried ATP (adenosine triphosphate) to pediatric patients with acute epidsodes of supraventricular tachycardia for therapeutic or diagnostic purpose and determined the safety and effectiveness of the drug. ATP was given...
A Clinical Study of the Effect of Early(<12 Months) Versus Late(12-24 Months) Onset in Infantile Asthma
Jae Won OH, Ji Yeon Lim, Ha Baik Lee
Clin Exp Pediatr. 1992;35(2):201-210.   Published online February 15, 1992
Asthma in infancy can be confused with a variety of airway diseases, because not all that wheezes is asthma and controversy exists as to the role of age of asthma onset in childhood asthma. This study was designed to examine the role of age and predictive capacity of elevated serum IgE for early asthma doset. We compiled data of asthmatics (n=56)...
Clinical Observation on Very Low Birth Weight Infants
Jong Soo Lee, Mi Young Yeo, Byung Hak Lim, Sang Geel Lee
Clin Exp Pediatr. 1992;35(1):44-50.   Published online January 15, 1992
Charts of very low birth weight infants weighing less than 1500 gms at birth were revieved and the results were analyzed. Infants were 152 in numbers, admitted to nursery in Fatima Hospital from January 1986 to December 1989 including outborns. Results were as follow: 1) The incidence of very low birth weight was 5.78/1000 among 26270 newborn infants. 2) Maternal high...
Clinical and statistical observation for very low birth weight infants.
Sung Shin Park, Ji Hee Jung, Dong Hwan Lee, Sang Jhoo Lee
Clin Exp Pediatr. 1991;34(12):1629-1640.   Published online December 31, 1991
We made clinical and statistical observation of 90 very low birth weight infants who were admitted at Soonchunhyang university hospital during the 6 years period from January 1985 through December 1990. The result obtained were as follows: 1) The incidence of very low birth weight infant during 6 years period was 0.68%, and the mortality rate was 488/1000 very low birth weight infants. 2) There was no obvious...
The effect of ultrasonic nebulized salbutamol in the first attacked wheezy infants.
Soo Young Kweon, Young Mi Hong, Gyung Hee Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1991;34(11):1505-1511.   Published online November 30, 1991
Wheezing is one of the most common symptom in the first 2 year of life. Although the effect of bronchodilator in wheezy infants was still debating, various form of bronchodilator has been tried untill now. This study was done to estimate the value of ultrasonic nebulized salbutamol as a bronchodilator test and maintenance therapy compared to epinephrine and aminophylline in 44 wheezy infants below 24...
A case of lipodystrophia centrifugalis abdominalis infantilis.
Kyu Young Lee, Sung Ho Cha, Byoung Soo Cho, Chang Il Ahn, Woo Young Sim, Choong Rim Haw, Moon Ho Yang
Clin Exp Pediatr. 1991;34(10):1452-1457.   Published online October 31, 1991
We report a case of lipodystrophia centrifugalis abdominalis infantilis in 24 month male. At age 18 months, his mother noticed a fairly well-defined depression of skin in the both inguinal and axillary area, which gradually spread centrifugally to the lower portion of abdomen and total inguinal and axillary region. The laboratory findings were unremarkable. Biopsy showed absense of subcutaneous fat in the affected area.
Indomethacin therapy in premature infants with patent ductus arteriosus.
Dug Ha Kim, Jung Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1991;34(10):1381-1390.   Published online October 31, 1991
Patent ductus arteriosus (PDA) is a common disease that occurred in 20 〜 40 percent of premature infants. The incidence of PDA is inversely related to the gestational age and birth weight. Hemodynamically significant PDA increases the morbidity and mortality of premature infants. So, the management of PDA is one of the major problems in neonatal intensive care unit. Based on experimental animal studies,...
A case of neonatal systemic candidiasis.
Eun Ae Park, Gyoung Hee Kim
Clin Exp Pediatr. 1991;34(9):1286-1293.   Published online September 30, 1991
Systemic infection with Candida albicans in very premature infants is frequently fatal or associated with significant morbidity in survivors. Several common practices in newborn intensive care units, such as insertion of indwelling catheters, provision of parenteral nutrition, and prolonged administra- tion of broad-spectrum antibiotics or aminophylline, are associated with an increased risk of systemic disease. We have experienced a case of systemic candidiasis in 1/365...
A study for mass screening of galactosemia using galactitol level by spot urine method among Korean infants.
Jin Tae Kim, Chong Won Bae, Sa Jun Chung, Chang Il Ahn, Suyama I , Isshiki G
Clin Exp Pediatr. 1991;34(7):949-958.   Published online July 31, 1991
For mass screening of the galactosemia, we used spot urine method using filter paper which was newly developed by Department of Pediatrics, Kyung Hee University Hospital and Department of Pediatrics, Osaka City University in Japan. We used control groups as followed, 7 of normal adults,- one patient of I, II, III types of galactosemia, respectively. The experimental groups were 62 infants of 0 to...
Clinical review of abdominal masses in infants and children.
Dong A Lee, Woo Ryoung Lee, Jae Ock Park, Chang Hwi Kim, Sang Jhoo Lee
Clin Exp Pediatr. 1991;34(3):380-387.   Published online March 31, 1991
We reviewed 34 patients with palpable abdominal mass among 5,920 infants and children who admitted to the department of pediatrics of Soon Chun Hyang University from Jun. 1, 1986 to Aug. 31，1989. The results were as follows: 1) The incidence was 0.57% and the male: female ratio was 1:1.3. The mass was noted before 1 year of age in 23.5% of cases and under 5 years...
Clinical studies of meningitis cases in children.
Chun Oh Lee, Song Nyeon Choi, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1991;34(2):206-216.   Published online February 28, 1991
A clinical studies were carried out on 442 cases who were admitted to the Department of Pediatrics, Kwangju Christian Hospital under impression of meningitis during a 7 year period form January, 1982 to December, 1989. The results are summerized; 1) No yearly fluctuation in incidence for both purulent and aseptic meningitis was noted, but decreasing tendency was clearly seen for tuberculous meningitis. 2) Purulent meningitis affected mostly babies...
A Clinical Study of Periventricular-Intraventricular Hemorrhage in Very Low Birth Weight Infants.
Myoung Jae Chey, Young Pyo Chang, Jung Hwan Choi, Yong Seung Hwang, Chong Ku Yun, In One Kim, Kyung Mo Yeon
Clin Exp Pediatr. 1990;33(10):1341-1352.   Published online October 31, 1990
34 very low birth weight infants weighing 1,500 gms or less, who were admitted to the neonatal intensive care unit of Seoul National University Children’s Hospital, were routinely studied with serial real-time brain ultrasonography from August 1, 1986 to July 31, 1988. Their medical records and the results of brain ultrasonography were analyzed to evaluate propor- tion, severity, timing, clinical findings, outcome, associated periventricular...
Changein Regional Cerebral Blood Flow Velocity in Premature Infant.
Young Kyoo Shin, Chang Sung Son, Joo Won Lee, Young Chang Tockgo
Clin Exp Pediatr. 1990;33(10):1333-1340.   Published online October 31, 1990
In order to estimate the influence of systemic hemodynamic change in cerebral blood flow before and after closure of ductus arteriosus in premature mewborn infants, blood flow velocities of internal carotid artery (ICA), anterior cerebral artery (ACA) and middle cerebral artery (MCA) were measured in 17 premature newborn infants by pulsed Doppler ultrasonography. The data was compared with those of normal full-term infants by...
Exogenous Surfactant Replacement Therapy of Hyaline Membrane Disease: A controlled clinical trial.
Ran Namgung, Chul Lee, Kook In Park, Dong Gwan Han
Clin Exp Pediatr. 1990;33(1):22-34.   Published online January 31, 1990
We conducted a clinical controlled trial of exogenous surfactant replacement therapy in premature infants with hyaline membrane disease at the neonatal intensive care unit of Yonsei University Medical Center form Nov. 1987 to May 1988. Sixteen premature infants with severe HMD were randomly assigned to control group or surfactant-treated group. Eight infants (mean gestational age 29.9±2.8 week, mean birth weight 1, 425±308.9 gm) were given...
Study on the Temperature Measurement in the Newborn Infants.
Eun Saing Jee, Young Pyo Chang, Jung Hwan Choi, Chong Ku Yun, Yong Ran Kim, Myoung Sook Lee
Clin Exp Pediatr. 1989;32(12):1632-1636.   Published online December 31, 1989
We measured body temperatures and stabilization times of 100 term and 52 preterm infants at four sites. The sites were core, aural, rectal and axilla in order of degree of temperature. There was significant difference between term and preterm infants (term infant higher, p<0.001). Mean difference between axillary and rectal temperatures was 0.501C(rectal higher). Mean difference between rectal and core temperatures was 0.10lC(core higher)....
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