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Original Article
The Clinical study of Acute Poisoning in Children.
Ji Ho Song, Sang Young Chung, Byoung Soo Cho, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(10):1331-1336.   Published online October 31, 1989
A clinical study was performed on 145 cases of acute poisoning who were admitted in pediatric department of Kyung Hee University Hospital during the past 15 years from Jan. 1973 to Dec. 1987. The results are as follows; 1) There was no significant annual differences in frequency of poisoning, and the peak incindence in a year was in April and July (12.4%). 2) The sex ratio of...
A Case of Early Infantile Epileptic Encephalopathy with Suppression-burst.
Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(9):1320-1323.   Published online September 30, 1989
The authors experienced a case of 45-day-old female newborn infant who showed the intractable tonic spasms with series formation and hypotonia. We diagnosed it through the evaluation of the clinical, radiological features including brain CT and electroencephalogram. The suppresion-burst pattern in EEG and clinical features aid to the confirmation of the diagnosis. A brief review of the related literature were made.
Two Case of Transient Bilirubin Encephalopathy in Newborn.
Eun Kyoung Sohn, Chong Woo Bae, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(9):1295-1299.   Published online September 30, 1989
More recently, several studies have been repotted about the abnormalities of auditory brainstem response (ABR) in hyperbilirubinemia of newborn. By using of ABR, visual evoked potenital and nuclear magnetic resonance techniques, some investigators suggested that transient alteration in ABR in severely jaundiced neonates indicated reversible transient subclinical or clinical bilirubin induced neurotoxicity. They thought it would be the early stage of kernicterus. We experienced two...
A Clinical Study of Kawasaki Disease Complicating Coronary Aneurysm.
Chong Sung Chung, Byung Yul Lim, Sung Ho Cha, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(9):1240-1247.   Published online September 30, 1989
Kawasaki disease is an acute febrile illness of unknown origin and most frequently affects infants and children younger than age 5 years. Coronary aneurysms are most serious complication in Kawasai diseas and are developed in 15〜20% of patients. We studied 15 children Kawaski disease complicating coronary aneurysms, who were admitted to the Kyung Hee University Hospital during the period of January 1984 through January...
A Study of Milk β-Glucuronidase Activity in Breast Milk Associating with Neonatal Jaundice.
Soo Chun Kim, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(9):1202-1209.   Published online September 30, 1989
Since the 1960s, several reports have been presented to explain how the ingestion of human milk is related to neonatal jaundice. Recently, the jaundiced neonates whose mother’s milk contain sub- stances (eg, pregnane 3a, 20β-diol, lipoprotein lipase, free fatty acid, β-glucuronidase etc) facilitating the reabsorption of unconjugated bilirubin in the neonatal intestine through the enhancement of the enterohepatic circulation, were called the breast milk...
Hypertrophic Cardiomyopathy in Infant of Diabetic Mother.
Jeong Sam Jeon, Soo Chun Kim, Chong Woo Bae, Sung Ho Cha, Chang Il Ahn
Clin Exp Pediatr. 1989;32(8):1138-1143.   Published online August 31, 1989
Generally, infant of diabetic mother (IDM) have complex multisystems disease resulting in a high incidence of perinatal morbidity and mortality. Hypertrophic cardiomyopathy (HCM)-IDM appears as the early onset, transient and non-familial cariomyopathy in neonatal period. The etiology of the left ventricular outflow obstruction in these neonates is not clear. But, it is possible that the asymmetrical septal hypertrophy was a manifestation of the generalized...
A Case of Doxorubicin-induced Dilated Cardiomyopathy.
Sang Young Jeong, Soo Chun Kim, Sung Ho Cha, Young Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(8):1132-1137.   Published online August 31, 1989
Doxorubicin is one of the most effective chemotherapeutic agents in the treatment of leukemia, lymphoma and various solid tumors. Because of dose-dependent degenerative cardiomyopathy, however, doxorubicin theraphy may be discontinued ineffectively early. Doxorubicin-induced conges- tive heart failure carries a very poor prognosis since it is lethal in 60% of patients. Various methods for evaluating the cardiotoxic effect have been employed such as EKG, systolic...
3 Cases of Prune Belly syndrome.
Chong Sung Chung, Chong Woo Bae, Byung Soo Cho, Chang Il Ahn, Ju Hie Lee, Moon Ho Yang
Clin Exp Pediatr. 1989;32(6):845-851.   Published online June 30, 1989
The prune belly syndrome is a rare congenital anomaly characterized by laxed, wrinkled abdominal wall, cryptorchidism and urinary tract anomalies. But it has wide spectrum of clinical severity, clinical presentation and other anomalies such as pulmonary and skeletal anomalies. We suggested that we should examine the abdominal wall carefully in order to detect mild form (class III) of prune belly syndrome when we...
Clinical Observation and Electroencephalographic Findings relatee to Prognostic factor in Neonatal Seizure.
Soo Chun Kim, Jung Sam Jeon, Chong Woo Bae, Sa Joon Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(6):816-822.   Published online June 30, 1989
To study the clinical prognosis of the neonatal seizure, we carried out a retrospective review on medical records of 40 neonates who were admitted to the Dept. of Pediatrics, Kyung Hee University Hospital between January 1979 and December 1986. The results from the study are summarized as follows 1) Male to female ratio were 1.8:1. In 50.0%(20/40) of newborn infants, neonatal seizure was detected under...
Spinal Muscular Atrophy Type 2 in Siblings.
Jeong Sam Jeon, Dong Hub Lee, Byung Soo Cho, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(5):718-723.   Published online May 31, 1989
We experienced two cases of spinal muscular atrophy, type 2 in 1 year 11 months old boy and 4 year 1 month old girl with the complaint of progressive muscular weakness on both lower extremities (frog leg position). Their development had been almost normal since birth and they could stand alone briefly at 12 months of age, but progressive muscular weakness had been apparent...
A Case of Mycoplasmal Meningitis Associated with Mycoplasma Pneumoniae Pneumonia.
Sang Young Jeong, Seung Koog Kim, Sung Ho Cha, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(4):556-560.   Published online April 30, 1989
Mycoplasmas have been recognized as pathogens of respiratory tract in children and adolescence, but clinically apparent pneumonia develops in only 3 to 10% of infected persons. Central nervous system complication, such as aseptic meningitis, meningoencephalitis. transverse myelitis, hemiplegia, cerebellar ataxia and psychosis, associated with Mycoplasma pneumoniae infection were developed in .0.1 % of all Mycoplasmal infection. We experienced a case of Mycoplasma pneumoniae pneumonia and...
Clinical Study of Encephalitis and Encephalopathy in Children.
Dong Hunb Lee, Soo Chun Kim, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(4):500-510.   Published online April 30, 1989
This study was undertaken to evaluate the electronencephalographic and clinical findings in 132 cases of encephalitis and encephalopathy in the Department of Pediatrics, Kyung Hee University Hospital for 9 years from Jan. 1979 to Dec. 1987. The results were summerized as follows; 1) The incidence of ecephalitis was 0.46%{86 cases) and the incidence of encephalopathy was 0.25 % (46 cases) among total in-patient (18,671). 2) Male...
Clinical Study of Patients with Benign Rolandic Epilepsy(BRE).
Seung Koog Kim, Sung Ho Cha, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(1):62-66.   Published online January 31, 1989
BRE, probably the commonest varierity of partial epilepsy in childhood has 6 characteristics; it occurs in children, without neuropsychiatric antecidents, never related to progressive cerebral lesion, interictal EEG shows Rolandic spikes, the seizure are varied and there is always recovery in puberty at the latest. We reviewed 70 patients with BRE to observe the age and sex distribution, EEG findings, clinical sign and symptoms, treatment...
A Case of Kartagener's Syndrome.
Young Jin Min, Chang Il Ahn, Kyung Sook Cho, Jong Dae Cho
Clin Exp Pediatr. 1988;31(11):1522-1526.   Published online November 30, 1988
We experienced a case of Kartagener’s syndrome in a 15 year-old male patient who showed bronchiectasis, sinusitis, and situs inversus by X-ray and physical examination. We report a case of Kartagener's syndrome and a brief review of literliture was done.
Studies in Anemia of Infancy and Children During Hospitalization.
Tae Kyu Hame, Jeong Sam Jeon, Kyu Chul Choi, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1988;31(10):1338-1345.   Published online October 31, 1988
This investigational work-ups were studied in 303 cases of anemia including 45 cases of severe degree anemia retrospectively among total inpatients of 3387 in the Department of Pediatrics, Kyung Hee University Hospital for recent two years form Mar. 1985 to Feb. 1987. The results were obtained as follows; 1) The orerall incidence of anemia among total inpatients(3387) was 8.9%(303 case). The incidence of severe anemia was...
Diagnostic Value of the Lung Perfusion Scan in Foreign body Aspiration.
Ki Hong Park, Chong Woo Bae, Byoung Soo Cho, Sa Joon Chung, Yong Mook Choi, Chang Il Ahn, Sun Wha Lee, Chang Il Cha
Clin Exp Pediatr. 1988;31(10):1301-1307.   Published online October 31, 1988
Lung perfusion scan was performed on 5 young children suspected as foreign body aspiration who had been admitted on the Department of Pediatrics, Kyung Hee University Hospital from May 1986 to January 1988. The results were as follows: 1) All children had been showed perfusion defect as compatible as acute obstructive lung disease by lung perfusion scan and foreign bodies in bronchial tree were proved on...
Lipoproteinelectropheresis pattern in Nephrotic Syndrome.
Soon Don Hong, Byung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1988;31(9):1163-1170.   Published online September 30, 1988
This study was undertaken to eluidate lipoprotein patterns in patients with childhood nephrotic syndrome by response to initial steroid therapy, serum albumin level in MCNS and other histologic classifications. The result were summerized as follows. 1) There were 19 cases (52.8%) of abnormal lipoprotein patterns by Fredrickson classifications, type Ila were 6 cases (16.7%), type lib were 1 cases (2.8%) and type IV were 12 cases...
A Case of Tsutsugamushi Disease.
Tae Kyu Hame, Soo Chun Kim, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1988;31(8):1048-1053.   Published online August 31, 1988
Rickettsial infection has not been identified in Korea since about 20-30 years before in Korea. However, there has been an increasing incidence of Tsutsugamushi disease in recent years. Tsutsugamushi disease is a variety of rickettsial infection to human causing abrupt onset of fever, headadie, vomiting, myalgia, and abdominal pain. In severe case, causing D.I.C., pulmonary edema, hypoalbuminemia and generalized edema. We reported a case of...
A Study of Maternal IgG Anti-A, B in ABO Hemolytic Disease of Newborn: Relation between Antibody titer in Mother and Clinical Severity in Neonate.
Chong Woo Bae, yong Mook Choi, Chang Il Ahn, Hyun Sook Chi
Clin Exp Pediatr. 1988;31(8):999-1006.   Published online August 31, 1988
Only IgG anti-A, or Anti-B cross the placenta and are responsible for the occurrence of ABO hemolytic disease of newbom(HDN). We have conducted the role of IgG anti-A or anti-B in mothers to occurrence and severity of the disease with were related to the level of antibodies in pathogenesis of ABO-HDN. This report presents the relation between the degree of bilirubin, hemoglobin concentration in ABO-HDN...
Changes in Auditory Brainstem Resposes in Hyperbilirubinemic Neonates Before and after Exchange Transfussion and Phototherapy.
Chong Woo Bae, Young Ho Ra, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1988;31(5):547-554.   Published online May 31, 1988
More recently, several studies of newborns involving ABR testing have demonstrated abnormalities following an exposure to moderate or severe hyperbilirubinemia. Jaundice in the early neonatal period is associated with significant transient aberrations of ABR, which suggested transient brain- stem encephalopathy. So, many authors mentioned that ABR may be a useful tool for the monitoring of early biliubin toxicity in infants who were at risk...
A Case of Myositis Ossificans Progressiva.
Yoeng Ho Ra, Sung Ho Cha, Byoung Soo Cho, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1988;31(2):271-275.   Published online February 28, 1988
A cases of Myositis ossificans progressiva in a 3 year-old girl who presented with hard mass in her right buttock and progressive hardening of muscles of her back and neck. The diagnosis was made on the basis of typical clinical features and characeristic radiologic findings. In addition to the cases report, a review of related literatures were discussed.
A Case of Reflux Nephropathy Associated with Cardiomyopathy.
Soon Hee Eom, Sung Ho Cha, Byung soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1988;31(2):258-262.   Published online February 28, 1988
Vesicoureteral reflux is the regurgitation of bladder urine into the upper urinary tract regardless of urinary tract infection. The results of vesicoureteral reflux are renal scarring, hypertension and proteinuria etc. We experienced a case of vesicoureteral reflux associated with cardiomyopathy in a 10 year old female patient who had dyspnea and orthopnea and treated with surgical and medical therapy. A brief review of the related...
Clinical and Statistical Observations of Bleeding Disorders in Childhood.
Ha Young Lee, Chong Sung Chung, Kyu Chul Choi, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1988;31(2):186-195.   Published online February 28, 1988
Developmental Changes of Auditory Brainstem Responses in Children.
Jeong Sik Min, Yeong Ho Ra, Chong Woo Bae, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1987;30(12):1387-1400.   Published online December 31, 1987
Auditory Brainstem Response(ABR) has been found to be useful for evaluating objective assessment of hearing thresholds, maturation of the brainstem and neurological disorders in the brainstem. Therefore it is essential to define normal ranges and accurate changes in the wave form of the ABR in children. This study was undertaken with the analysis of 243 ABR in children with normal otological, developmental, neurological...
Upper Gastrointestinal Fiberoptic Endoscopy in Children.
Dong Hyup Lee, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn, Young Il Min
Clin Exp Pediatr. 1987;30(8):868-873.   Published online August 31, 1987
We observed 63 cases ranging in age from 3 years to 15 years seen by gastrofibroscopy in Dept, of Int. Med. and Dept, of Ped. of Kyung hee Univ. Hospital from January 1980 to December 1985 and following results were obtained 1) The male to female ratio was about 1:1.17. The frequency of the age distribution was 1.6% below 5 years, 25.4% in 6-10 years...
Clinico-Epidemiological Study on Leprosy Patients in Children.
Koo Jeoung Jung, Byoung Soo Cho, Sung Ho Cha, Sa Jun Chung, Chang Il Ahn, Do Seo Koo, Do Il Kim
Clin Exp Pediatr. 1987;30(7):769-776.   Published online July 31, 1987
Clinico-epidemiological study on 44 patients with leprosy in less than 20-year-old children visited to Institute for Leprosy Research, Korean Leprosy Control Association during past 9 years from January, 1978, to August, 1986 was carried out and the following results were obtained. 1) Age at time of visit was shown peak in the age group of 16-20 years (34 cases, 77%), but non in the age...
A Clinical Study on Patients with Mycoplasma Pneumoniae Pneumonia in Childhood.
Yeong Ho Ra, Sung Ho Cha, Sa Joon Chung, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1987;30(7):759-768.   Published online July 31, 1987
Clinical features of 96 cases (46 Mycoplasmal pneumonia: Group I, 50 Non-Mycoplasmal pneumo- nia: Group II) above 2 years of age were studied prospectively from December, 1985 to June, 1986 who were admitted to the Dept, of Pediatrics, Kyung Hee University Hospital. The summary of the study is as follows: 1) Among the total 96 cases with pneumonia above 2 years of age, the frequency...
Immunologic Function in Early Phase of Various Glomerulonephritis.
Soon Don Hong, Hyoung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1987;30(7):735-741.   Published online July 31, 1987
Abnormal lymphocyte function has been postulated to have a pathogenetic role in nephrotic syndrome. To assess immunologic parameters in the pathogenesis of various glomerulonephritis in early phase, in prdiatric department of Kyung Hee University Hospital from September 1985 to June 1986, serum immunoglobulin concentration and T cell subsets were measured in 32 children and compared with normal control group (n=30). Further studies are needed to...
Significance of Brain CT in Children with Meningitig.
Myeong Yeon Lee, Byoung Soo Cho, Sa Jun Chung, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1987;30(6):640-650.   Published online June 30, 1987
This study was undertaken to evaluate the significance of brain CT in children with meningitis. The findings of brain CT in 71 children with meningitis were evaluated in relation to the clinical outcome. We divided 71 cases into 5 groups according to clinical outcome on discharge, that is, Group I: Recovery. Group II: Discharge with improvement. Group III: Discharge with residual sequalae. Group IV:...
Cytogenetic Study on Chromosome Aberration in Children.
Chong Woo Bae, Chang Il Ahn, Bo Hoon Oh, Kap Soon Ju
Clin Exp Pediatr. 1987;30(6):633-639.   Published online June 30, 1987
We have conducted a retrospective study on chromosomal aberrations in children, aged under 15 years old, who had been refered to cytogenetic laboratory at Kyung Hee University Hospital from 1977 to 1986 Base upon the Karyotypes of lymphocytes and chart records, the following results were obtained; 1) Chromosomal aberrations of various types were found in 101 cases in children. 2) Age distribution revealed 65.3% were under the...