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Original Article
Periventricular-Intraventricular Hemorrhage in the Full-term Infant
Hee Sup Kim, Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun, In One Kim
Clin Exp Pediatr. 1994;37(5):642-648.   Published online May 15, 1994
Intraventricular hemorrhage (IVH) is common in the premature infants and occurs mainly in subependymal germinal matrix. In contrast, IVH in the term infants is rare and different in pathogenesis and bleeding sites from those of the premature infants. Most studies of IVH in term infants have been studied by computerized tomography and postmortem examination. Brain ultrasonography which has become a...
Packed Red Cell Transfusion in Neonate : Effects of Age of Red Cells on Serum Laboratory Values and Readjustment of Hematocrit Values after Transfusion
Dong Ha Lee, Jin Kyung Kim, Heng Mi Kim
Clin Exp Pediatr. 1994;37(4):452-456.   Published online April 15, 1994
Sick neonates often require periodic small volume transfusion(10mg/kg) to replace blood draw for laboratory monitoring during their hospital stay. The effect of packed red cell transfusion on the hematocrit, potassium, ionized calcium, acid base status, glucose and indirect bilirubin was investigated in 25 transfusions. Analysis of transfused blood by the age of the red cells, older red cells (more than...
Hypercalciuria in High Risk Neonate
Eun Sun Kim, Seung Joo Lee
Clin Exp Pediatr. 1994;37(3):322-331.   Published online March 15, 1994
The incidence and risk factors for hypercalciuria were studied in 23 sick preterm (Group I), 36 well preterm (Group II), 16 sick term (Group III) and 41 well term (Group IV) neonates who were admitted to NICU and nursery of Whwa Woman's University Hospital from May 1988 to February 1992. The results were as follows: 1) The incidences of hypercalciuria were 73.9%...
Intravenous Immunoglobulin for Prophylaxis of Neoneatal Sepsis in the Premature Infants
K.H. Hur, S.H. Kim, H.S. Kim, M.J. Chey, K.H. Kim, H.S. Lee
Clin Exp Pediatr. 1993;36(11):1534-1541.   Published online November 15, 1993
Newborn premature babies have low levels of transplacentally acquired maternal immunoglobulin which is mostly transferred after 32∼34weeks gestation, therefore they may have IgG deficiencies that incerase their susceptibillity to bacterial infection. We preformed this study to determine whether intravenous immunoglobulin (IVIG) therapy improves mortality or infection occurrence rate. From 1 october 1991 to 31 july 1992, 73premature newborn iffants with gestational age≤34weeks...
The Significance of Nucleated Red Blood Cell Counts in Low Birth Weight Neonates
In Ho Song, Weon Kee Lee, Hye Lim Jung, Dong Hyuck Keum
Clin Exp Pediatr. 1993;36(11):1526-1533.   Published online November 15, 1993
We studied to assess the relationship between intrauterine growth retardation and the increased nucleated red blood cell counts (NRBC) in small for gestational age (SGA) and appropriate for gestational age (AGA) neonates with low birth weight. We also evaluated the nucleated red blood cell counts in low birth weight neonates who had either perinatal asphyxia or hyaline membrane disease (HMD)...
Indirect Measurement of Blood Pressure in Neonates Using an Automatic Noninvasive Oscillometric Monitor
Jung Hea Park, Hea Jin Choeh, Eun Sik Kang, Chong Sung Chung, Kyuchul Choeh
Clin Exp Pediatr. 1993;36(9):1211-1218.   Published online September 15, 1993
The measurement of blood pressure in neonates is an important diagnostic procedure. But the measurement of blood pressure has not been performed routinely because of difficulty in measuring blood pressure and varable normal range according to measuring apparatus. Recently some accurate and convenient apparatus of measuring blood pressure have been introduced in neonatal care, so the reference values...
Statistical Observation on Neonate
Dong Il Park, Chel Gi Kim, Jin Bok Hwang, Chang Ho Han, Hye Le Chung, Young Dae Kwon
Clin Exp Pediatr. 1993;36(8):1080-1093.   Published online August 15, 1993
A statistical obsevation was performed on 13,317 cases of neonates who had been delivered at Taegu Catholic Hospital during the past 3 years from Jan. 1 st 1988 to Dec. 31 st 1990. The results obtained were as follows: 1) Among 13,317 neonates, the male was 7,234 and the femlae 6,083, with the sex ratio of male to female being 1.19:1 2) Percentage...
Comparison and diagnostic Accuracy of Stable Microbubble Rating Test and Shake Test for the Early Detection of Respiratory Distress Syndrome
Hyeon Gon Kim, Sang Hyun Byun, Young Hun Chung
Clin Exp Pediatr. 1993;36(7):913-918.   Published online July 15, 1993
Respiratory distress syndrome of preterm infants remains a significant cause of morbidity and mortality. Early, just after birth, prediction and recognition of RDS is so important. The precision and reliability of the stable microbuble test (SMR) and shake test as a predictor of respiratory distress syndrome were studied. A 11-=neonate who was born at Chungnam National University Hospital between November 1991...
Clinical Assessment of Neonatal Transient Tricuspid Insuffieciency - Doppler Echocardiographic Study-
Se Geun Park, Dong Gun Park, Ji Hee Park, Chang Sung Son, Joo Won Lee, Young Chang Tockgo
Clin Exp Pediatr. 1993;36(6):785-790.   Published online June 15, 1993
Eight neonates with transient tricuspid insufficiency are presented which was confirmed clinical and two dimensional echocardiographic assessment. We found that two dimensional Doppler echocardiography was very useful in the detection of transient tricuspid insufficiency during neonatal age as noninvasive method. Transient tricuspid insufficiency is a clinical disorder in the newborn period caused by myocardial dysfunction, secondary to asphyxia with or without...
Bilateral Torsion of the Testes in a Newborn Infant
Eun Sook Kim, Hang Mi Kim, Song Kwang Jung
Clin Exp Pediatr. 1993;36(5):721-724.   Published online May 15, 1993
We report one case of bilateral testicular torsion. A 4000 gm male infant, born by cesarean section due to induction failure at 42 weeks gestation, was hospitalized at 9 days of age secondary to bilateral testicular mass. Physical examination revealed an healthy baby with enlarged, firm, nontender mass on both sides of the scrotum. Transillumination of the mass shwed no transmission...
Clinical Observation of Neonatal Sepsis
Jin A Son, Soon Wha Kim, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1993;36(5):671-679.   Published online May 15, 1993
Ninety two cases of culture proved neonatal sepsis who had been admitted to pediatric department, National medical Center, during 7 years from Jan, 1984 to Dec, 1990 were reviewed clinically and the following results were obtained. 1) The frepuency of neonatal sepsis was 3.1% and male to female sex ratio was 1.9:1, Sepsis was more prevalent in prenature infants (9.9%) than...
Evaluation of the Serum Erythropoietin Levels in Neonates
Soo Young Kweon, Gyoung Hee Kim
Clin Exp Pediatr. 1993;36(1):67-72.   Published online January 15, 1993
Erythropoietin is the major hormonal regulator of erythropoiesis. It is controlled by many factors induct=ing hypoxia in tissue. The serum erythropoietin levels of neonates have shown gradual decrease untill 1 month of age. Which they are reactivated in the period of pysiologic anemia. This change is exaggerated if the neonates are born prematurely, and the levels of erythropoietin respond to...
Clinical analysis on newborn infants treated with mechanical ventilation.
Yeon Sim Kim, Dae Ho Choi, Cheol Woo Park, Yeon Kyun Oh
Clin Exp Pediatr. 1991;34(10):1346-1355.   Published online October 31, 1991
Clinical analysis of 48 neonates who treated with Mechanical ventilation in NICU at Won-Kwang University Hospital from February 1987 to July 1990 was performed. The results were as follows; 1) According to diagnostic categories, hyaline membrane disease was the most common in 26 cases (54.2%), and then postasphyxia syndrome 10cases (20.8%), apnea of prematurity 3cases (6.2%), sepsis 3 cases (6.2%)，in their order. 2) 29 cases (60.4%) were bom...
Clinical charateristics of pregnancy-induced hypertensive mothers and their neonates.
Soo Jeong Ryu, Jin Sook Kim, Kyong Hoon Choi, Myong Jin Kim, Mi Na Lee
Clin Exp Pediatr. 1991;34(7):929-933.   Published online July 31, 1991
The results were as follows; 1) The mean platelet count of peripheral blood in pergnancy-induced hypertensive mothers was 221, 733±17,357/mm3 which was than control Significant thrombocytopenia was encountered in 8 cases 2) Meanwhile their newborns showed neutropenia and prolongation of prothrombin time. 3) Intrauterine growth retardation could be assesed in 8 out of 30 newborns from these mothers.
A clinical study on neonatal bacterial meningitis.
Yong Won Park, Jung Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1991;34(6):763-770.   Published online June 30, 1991
Clinical courses of 12 neonates who were confirmed as neonatal bacterial meningitis by CSF culture or CSF latex agglutination test from January, 1986 to June, 1990, emphasizing on their complications and treatments, were evaluated. The results were summarized as follows; 1) The most common etiologic organism was E. coli (33.3%). 2) Two most common complications were ventriculitis (66.7%) and hydrocephalus (66.7%). 3) EVD with intraventricular antibiotics therapy was only...
Acute pyogenic arthritis of hip in neonate and infant.
Mi Jung Kim, Young Ah Lee, Young Pyo Chang, Hoan Jong Lee, Jung Hwan Choi, Chong Ku Yun, Hak Jin Min, In Ho Choi
Clin Exp Pediatr. 1991;34(2):197-205.   Published online February 28, 1991
Acute pyogenic arthritis of hip is a serious infection that can lead to truly devastating complica- tions especially in neonatal period and infancy. Clinical survey on twelve neonates and infants (14 hip joints) with acute pyogenic arthritis of hip who were admitted to the Departments of Pediatrics and Orthopedic Surgery, Seoul National University Hospital from Jan. 1980 to Dec. 1989 were done. The results...
Clinical Obervation in 40 Cases with Neonatal Sepsis.
Jung Hee Lee, Jae Jin Park, In Kyung Sung, Byung Churl Lee
Clin Exp Pediatr. 1990;33(11):1489-1494.   Published online November 30, 1990
Sepsis is still one of major causes of mortality and morbidity in neonatal period and early diagnosis and appropriate treatment for neonatal sepsis is difficult due to its vague clinical manifestation and rapid progress. An analysis of 40 cases of neonatal sepsis confirmed by clinical manifestation and blood cultures from Jan. 1986 to Dec. 1989 at nursery of St. Mary’s Hospital of Catholic University...
Statistical Observation on Neonate.
Hong Ja Kang, Nam Hyuk Joo, Soon Ok Byun, Ji Sub Oh
Clin Exp Pediatr. 1990;33(8):1037-1047.   Published online August 31, 1990
Statistical observation was performed on 11,857 cases of neonates which were seen in the nursery, Pusan, Wallace Memorial Baptist Hospital, during the past 5 years from Jul. 1983 to Jun. 1988. The results were as follows: 1) Among 11,857 neonates, the percentage distribution by birth weight was 6.1% for 2,500 gm or less, 3.7% for 4,001 gm or more and the sex ratio of male...
Diaphragmatic Movements in Neonates.
Hee Shang Youn, Han Wook Yoo, Moon Hong Do, Jung Hyun Cho
Clin Exp Pediatr. 1990;33(7):901-906.   Published online July 31, 1990
Right diaphrgmatic movement was recorded in 25 neontes when asleeping or in quietly awake state. Using 5-MHz transducer of Aloka 860 color echocardiography we measured those in the supine flat, supine head up, supine head down and prone flat positions. Results were as follows: 1) Normative data of right hemidiaphragmatic movement of 25 neonates were obtained in the positions. 2) Deaphragmatic movement of posterior third was significantly greater...
Glucose Disappearance Rates in Neonates.
Won Mo Yang, Wea Kyung Shin, Whang Min Kim, Back Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1989;32(12):1637-1641.   Published online December 31, 1989
We measured the glucose diappearance rate(Kt) in 24 normal neonates and in 19 ill neonates by intravenous glucose tolerance test. The results were as follows: 1) The glucose disappearance rate of 2-day-old normal neonates was 1.59±0.8%/min. 2) The glucose disappearance rate of ill neonates who had negative culture studies was 2.08±l. 4%/min. 3) There was no significant difference in glucose disappearance rate between normal neonates and ill neonates who had...
Blood Level of Phenobarbital in Treatment of Seizure After Neonatal Asphyxia.
Ji Yean Lee, Heng Mi Kim, Doo Hong Ahn
Clin Exp Pediatr. 1989;32(9):1265-1272.   Published online September 30, 1989
In this study, we attempted to determine an optimal first dose of phenobarbital for the treatment of seizures in the asphyxiated full term neonates. Blood samples were obtained 2 to 48 hours after the administration of final effective loading dose and plasma levels were determined by the EMIT system. Four groups of neonates were studied. Six neonates (Group 1) received an intravenous loading dose of...
A Clinical Survey of Abdominal Masses in the Neonate.
Beyong Il Kim, Jung Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1989;32(7):926-932.   Published online July 31, 1989
We reviewed 22 newborn patients with palpable abdominal mass among 9, 834 newborn infants admitted to nursery and NICU of Seoul Natinal University Children’s Hospital from Jan. 1, 1983 to Dec. 31, 1987. The results were summarized as follows: 1) The incidence was 2.2/1,000 admission. The difference of incidence was not significant between preterm infants and term infants. 2) The most common etiology of neonatal abdominal masses is...
Pancreatic ISlet-cell Adenoma in a Neonate.
Kyu Bum Cho, Yang Bin Im, Dong Hwan Lee, Sang Jhoo Lee, Tae Jeong Kwon, Dong Hwa Lee
Clin Exp Pediatr. 1988;31(12):1650-1656.   Published online December 31, 1988
Islet cell adenoma is a rare cause of severe neonatal hypoglycemia. A newborn infant with severe symptomatic hypoglycemia had persistent hypoglycemia in spite of therapy with parenteral glucose solution. Islet-cell adenoma of mixed islet-acinar type was found when subtotal pancreatectomy was performed at 42 days of age. Following surgery she had a transient hyperglycemia and required isulin for 40 days. She has remained normoglycemic but...
A Clinical Study of Hospitalized Neonates with Fever.
Youn Mo Ahn, Chang Ryul Kim, Woo Gill Lee, Soo Jee Moon
Clin Exp Pediatr. 1988;31(11):1437-1444.   Published online November 30, 1988
Life-threatening bacterial infections such as meningitis, septicemia, and pneumonia in the neonates are more common than at any other time in life and signs of these infections are often subtle and non-specific. Because of these factors, the patient who has persistent fever will almost always be started on parenteral antibiotics immediately following evaluation. On the other hand there is also evidence that the hospital...
A Clinical Ovservation of Tetanus Neonatorum.
Gyeong Hye Jung, Hyo Sin Kim, Ock Seung jeong, Son Sang Seo
Clin Exp Pediatr. 1988;31(8):992-998.   Published online August 31, 1988
A clinical study in 75 cases who were hospitalized and diagnosed as neonatal tetanus at II Sin Christian Hospital during the last 10 years (1976-1985) is reported. The results were as follows; 1) The mean annual incidence was 0.29% and the overall mortality rate was 29.4%. 2) Sex ratio of male to female was 1.6:1. 3) Home delivery without sanitory facilities was the most common problem (86.5%). 4) Most of...
The Relationship of Specific Gravity by Refractometer and Osmolality in the Urine of Neonates.
Hae Young Lee, In Soon Ahn, Jae Seung Yang, Beak Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1988;31(5):555-558.   Published online May 31, 1988
Comparison of urinary specific gravity by refractometer and osmolality in 238 neonates demonstrated as followings; 1) The regression line is represented by the equation: Y = 107+14.2 (X-1000) while Y = osmolality in mosm/kg X = Specific gravity by refractometer r=0.8545 2) Osmolality is the only accurate measure of urine concentration in newborn infants. If the specific gravity by refractometer is used to screen for urine concentration, an elevated level...
A Case Report of Isoimmune Neonatal Thrombocytopenie Purpura.
Hye Ran Byun, Kyung Ha Ryu, Soon Hee Kim, Moon Ja Kim, Keun Lee
Clin Exp Pediatr. 1987;30(12):1452-1455.   Published online December 31, 1987
Isoimmune thrombocytopenic purpura is an uncommon cause of purpura in the newborn infant, caused by fetal-maternal platelet incompatibility. The maternal isoantibodies against fetal platelet antigens, which are lacked in mother’s platelets, cross placenta and cause destructions of baby’s platelet. A bady bom with IITP was diagnosed in the first day of life and treated successfully with platelet concentrate of mother’s blood.
A Case of Pyeloplasty in Neonatal Bilateral U-P-J Obstruction.
In Soon Ahn, Jung Sik Rhim, Baek Keun Lee, Jae Mann Song
Clin Exp Pediatr. 1987;30(11):1294-1298.   Published online November 30, 1987
Ureteropelvic junction obstruction has been discussed extensively in literature, but most reports refer to adults or young children. Neonatal bilateral U-P-J obstruction has not been reported in Korea. Herein we present with bilateral ureteropelvic junction obstruction in neonate. Repair was achieved successfully using a non-intubated, nonstented, dismembered pyeloplasty. Renal function shows normal during the follow-up periods.
PPD Conversion Rate and Complications According to the Different Time of BCG Vaccination.
Kyung Hyo Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(5):487-490.   Published online May 31, 1987
BCG vaccination shortly after birth has shown to protect against tuberculosis in some studies. PPD conversion rate and complications were compared between 174 neonates who received BCG vaccine within 1 week after birth and 330 infants who received BCG vaccine at the 1 month of age. The results were as follows: 1) The PPD conversion rate was 20.11% in the neonates who received vaccine within...
A Prospective Study ot Neonatal Acute Renal Failure: The Significance of Various Diagnostic Indices.
Kyung Hyo Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(4):378-384.   Published online April 30, 1987
Acute renal failure is defined as a sudden decrease in renal function resulting in progressive retention of nitrogenous waste products. Acute renal failure should be suspected in any infant who has a sustained decrease in urine output to less than 1 ml per kg per hour, a blood urea nitrogen level above 20 mg per dl, a serum creatinine level greater than 1.0...