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Distribution of Anti-Mumps IgM Antibody in Children Presumptively Diagnosed of Mumps
Sung Hee Oh, Do Hack Yum, Jin Han Kang, Young Mo Sohn, Hoan Jong Lee, Bok Yang Pyun, Young Jin Hong, Chang Hwi Kim
Clin Exp Pediatr. 2001;44(1):17-25.   Published online January 15, 2001
Purpose : Outbreaks of mumps continue to occur, even though the number of patients diagnosed of mumps has decreased considerably with the widespread use of vaccine. The accurate diagnosis of mumps is needed to understand the epidemiology of mumps and analyse the safety and effectiveness of vaccine. Therefore, we attempted to appraise the accuracy of provisional diagnosis of mumps in...
Original Article
Antibody Response and Adverse Reaction Following Immunization with MMR Vaccine Produced on Human Diploid Cells in Korean Children
Sung Hee Oh, Jin Han Kang, Young Mo Sohn, Hoan Jong Lee, Bok Yang Pyun, Chang Hwi Kim
Clin Exp Pediatr. 2000;43(4):489-495.   Published online April 15, 2000
Purpose : This prospective study was performed to evaluate the immunogenecity and safety of MMR vaccine(Triviraten Berna¢c) in Korea children. Methods : Seventy-three infants aged between 12 to 18 months were recruited from several university hospitals between December 1995 to June 1996. MMR vaccine(Triviraten Berna¢c) was administrered and blood was obtained before and 6-10 weeks after vaccination. IgG antibodies against measles,...
Immune Response to SA14-14-2 Live Attenuated Japanese Encephalitis Vaccine
Min Soo Park, Hye Ok Rho, Young Mo Sohn, Laura Chandler, Robert Shope, Theodore F. Tsai
Clin Exp Pediatr. 2000;43(3):351-359.   Published online March 15, 2000
Purpose : SA14-14-2 live attenuated Japanese encephalitis(JE) vaccine has been administered safely and effectively to more than 100 million children in China since 1988, and recently licensure of the vaccine in Korea has been sought. Immune response to the vaccine was investigated. Methods : In the first clinical evaluation of the vaccine outside of China, we monitored side effects in 93...
Humoral and Cell Mediated Immune Response After Immunization with Varicella Vaccine(Oka/LG)
Young Mo Sohn, Hye Ok Roh, Mi Lim Goo, Bok Ryeon Park, Joo Hong Park, Gook Jin Lim
Clin Exp Pediatr. 1998;41(2):170-178.   Published online February 15, 1998
Purpose : We evaluated the humoral and cellular immune response to varicella-zoster virus after vaccination with varicella vaccine(Oka/LG strain). Methods : The seroprevalence rate of fluorescent antibody to membrane antigen(FAMA) was evaluated among 178 children and 15 adults. After vaccination, seroconversion rate of FAMA, varicella-zoster virus(VZV) specific IgG and cell mediated immune response to glycoprotein Ⅰwas performed. Results : The seropositive rate...
Report of Nationwide Epidemiology of Aseptic Meningitis Outbreak in 1993 in Korea
Sung Hee Oh, Moo-Song Lee, Jin Han Kang, Chang Hwi Kim, Chong Young Park, Young Mo Sohn, Hoan Jong Lee, Chung Sik Chun, Sang Mann Shin
Clin Exp Pediatr. 1996;39(1):42-52.   Published online January 15, 1996
Purpose : There has been no nationwide report pertaining to the epidemiology of aseptic meningitis, although a great numer of patients have been diagnosed of the illness. Therefore, we report an explosive outbreak of aseptic meningitis occured in a nationwide scale in 1993. Methods : Aseptic meningitis epidemiology surveillence was performed retrospectively on the patients diagnosed of aseptic meinigitis from January...
Medical Lecture Course
HIV Infection in Children
Young Mo Sohn
Clin Exp Pediatr. 1995;38(8):1023-1035.   Published online August 15, 1995
Original Article
Immunogenicity and Safety of Live Attenuated Vaccine(MAV/06srtain) on Healthy Children and Immunocompromised Children
Young Mo Sohn, Chul Joo Yu, Pyung Kil Kim, Kir Young Kim, Chong Young Park, Mi Ran Kim, Woo Kap Jeung, Kyu Kye Hwang, Gyu Jin Woo, Song Yong Park
Clin Exp Pediatr. 1995;38(6):771-777.   Published online June 15, 1995
Purpose : To study the safety and immunogenicity of new live attenuated varicella vaccine (MAV/06strain) in normal healthy children and immunocompromized children in Korea. Methods : Blood samples for fluorescent antibody to membrane antigen(FAMA) assay were taken before the vaccination among seven hundred forth five healthy children and twenty two nine immunocompromised children. One hundred and seventy seven children and twenty...
Safety and Immunogenicity of Live Attenuated Varicella Virus Vaccine(MAV/06 strain)
Young Mo Sohn, Chong Young Park, Kyu Kye Hwang, Gyu Jin Woo, Song Yong Park
Clin Exp Pediatr. 1994;37(10):1405-1413.   Published online October 15, 1994
Detection of Cytomegalovirus DNA in Urine Culture Using Polymerase Chain Reaction
Young Mo Sohn, Won Young Lee
Clin Exp Pediatr. 1993;36(5):626-633.   Published online May 15, 1993
Polymerase chain reaction(PCR) amplication was used to detect cytomegalovirus (CMV) in tissue culture from the ruine of newborns and patients who was suspected CMV infection. Synthetic oligonucleotide primer pairs were used to amplify DNA from the magor immediate-early and the phosphoprotein 150 genes of CMV AD 169. Amplified products were detected by gel electrophoresis and by dot-blot hybridization with oligonucleotide...
Measles in Previously Vaccinated Children -Rapid Changes in Measles Vaccine Potency by Storage Temperature-
Young Mo Sohn, Seung Kyu Lee, Kyu Hyun Park, Won Young Lee
Clin Exp Pediatr. 1992;35(12):1639-1645.   Published online December 15, 1992
Clinical Features of Twelve Coxiellemia Pediatric Patients in Korea
Chuhl-Joo Lyu, Dong Soo Kim, Young Mo Sohn, Ki Sup Chung, Kir-Young Kim, Won Young Lee
Clin Exp Pediatr. 1992;35(9):1220-1225.   Published online September 15, 1992
Coxiella burnetii is a rickettsial organism and extremely infectious for humans animals. The infection caused by this organism is endemic throughout the world. Although it has not been reported in Korea because of the nonspecific clinical manifestations, the difficulties in diagnosis, and the underestimate of this disease. Update this infection has been misdiagnosed as other disease. We experienced twelve cases of...
Statistical Observation for the Pediatric Patients in ICU
Ki Hun Eum, Chang Ho Hong, Young Mo Sohn, Chul Lee, Pyung Kil Kim
Clin Exp Pediatr. 1992;35(6):762-768.   Published online June 15, 1992
A statistical study was performed on 221 ICU cared pediatric patients who were admitted to the department of pediatrics, Yonsei university college of medicine, Seoul, Korea from Apr. 1983 to Mar. 1991. The results were as follows : 1) Total number of subject were 221, it was 7.5% of total ICU patients and 1.3% fo total admitted pediatric patients. The male to...
Congenital cytomegalovirus infection: incidence and clinical outcome.
Young Mo Sohn, Kook In Park, Chul Lee, Dong Kwan Han, Won Young Lee
Clin Exp Pediatr. 1991;34(10):1365-1372.   Published online October 31, 1991
In order to assess the rate of congenital cytomegalovirus (CMV) infection in newborns, CMV IgG antibody was studies at about 37.5 weeks gestation in 309 mothers and a positive rate of 96.4% was obtained. Virus culture for CMV from urine of 514 neonates less than 1 week after birth resulted in CMV growth in 6 neonates showing a 1.2% congenital infection rate. In...
A case of neonatal herpes simplex virus encephalitis.
Kook In Park, Young Mo Sohn, Dong Soo Kim, Ran Namgung, Chul Lee, Dong Gwan Han, Won Young Lee, Ki Keun Oh, Myung Joon Kim
Clin Exp Pediatr. 1991;34(9):1276-1285.   Published online September 30, 1991
Neonatal herpes simplex virus infection still remains a life-threatening infection for the newborn. With an increasing incidence of genital herpes and an increase in the incidence of neonatal herpes simplex virus infections, it is important that pediatricians and neonatologists continue to maintain a high index of suspicion in infants whose symptoms may be compatible with herpes simplex virus infections so that early identification leads...
Immunogenecity of Low-Dose Administration of Hepatitis B Virus Vaccine in School Aged Group.
Young Mo Sohn, Pyung Kin Kim, Kyung Soon Song
Clin Exp Pediatr. 1987;30(11):1221-1227.   Published online November 30, 1987
For evaluation of immunogenecity of low-dose of hepatitis vaccine-prepared by Korea Green Cross Corporation 74 school aged children were given routine schedule (0, 1, 6 months). A dose of 5 microgram was administered intramuscullary in the cases of age under 10 yrs of age and 10 microgram was administered in the cases over 11 yrs of age. An adequate follow-up observation of antibody titer...
A Case of Cloverleaf Skull; Kleeblattschael Syndrome.
Chang Hyon Yang, Kyu Earn Kim, Chang Ho Hong, Young Mo Sohn, Don Gyu Yang, Kee Keun Oh
Clin Exp Pediatr. 1987;30(4):456-460.   Published online April 30, 1987
A case of Cloverleaf skull; Kleeblattschadel syndrome in a 70-day old male infant with facial deformity since birth was seen. The diagnosis was made on the basis of typical morphologic clinical features an radiologic findings. A brief review of the related literature was given.
The Response of Leukocytes in the Peripheral Blood Following Exchange Transfusion in the Newborn.
Young Mo Sohn, Yu Young Chang, Young Ho Kim, Kir Young Kim
Clin Exp Pediatr. 1983;26(11):1049-1054.   Published online November 30, 1983
We have studied the hemoglobin level and. leukocyte count of 23 fullterm and 1 premature jaundiced babies soon after exchange transfusion and daily thereafter until 7 days. The resixlts are: 1) One exchange transfusion was enough in 16 patients but 8 were required more than 2times of exchange transfusion. The maximum is 6 times. 2) The postnatal age was...
Case Report
Congenital Hiatal Hernia Associated with Anemia.
Young Sook Hong, Young Mo Sohn, Pyung Kil Kim
Clin Exp Pediatr. 1982;25(5):523-527.   Published online May 31, 1982
Surgically corrected congenital hiatal hernia associated with anemia has been presented. A 1 year old boy has been complained of severe pallor and fever on admission. Reentgenologic examination revealed thoracic stomach and then the hernia was repaired by transabdominal approach. It was found to be a paraesophageal type hiatal hernia. Pathogenesis and complications of congenital histal hernia were discussed and...
Original Article
Clinical Observation of Hemolytic Anemia in Children Except Isoimmunization.
Hak Yong Kim, Young Mo Sohn, Kwan Sub Chung, Kir Young Kim, Duk Jin Yun
Clin Exp Pediatr. 1981;24(12):1149-1156.   Published online December 15, 1981
Hemolytic anemia is caused by early destruction of red cells and there are many etiologies,ecently, prosthetic devices are used frequently to correct cardiac diseases and they also cause hemolytic anemia. We performed clinical analysis of 74 patients with hemolytie anemia who had been diagnosed at Severance hospital in recent 10 years. Results were as follows: 1)In 74 cases, male were 46...
Cluster of Guillain-Barre Syndrome.
Young Mo Sohn, Sung Sik Lee, Kwan Sub Chung, Ki Sub Chung, Seung Kyu Lee, Pyung Kil Kim, Kir Young Kim, Duk Jin Yun, Kyoung Ja Cho
Clin Exp Pediatr. 1981;24(9):820-825.   Published online September 15, 1981
Of 7 cases of Guillain-Barre syndrome reviewed, which was admitted to the Department of Pediatrics Yonsei University, College of Medicine during 3 months period from July through September 1980, serologic surveys for an infectious agent were found to be without demonstrable causes such as cytomegalovirus and measles virus. We reviewed 87 acses of Guillain-Barre syndrome, which was admitted to our...
Case Report
Recovery of Bilateral Renal Vein Thrombosis after Peritoneal Dialyis in a Newborn Neonate.
Young Mo Sohn, Nan Ae Kim, Sang Hak Park, Ki Young Lee, Pyung Kil Kim
Clin Exp Pediatr. 1981;24(8):772-776.   Published online August 15, 1981
A 4 day old male neonate with severe dehydration, uremia, and hyperbilirubinemia presented with bilateral renal vein thrombosis. Following exchange transfusion and peritoneal dialysis renal function returned to normal without nephrectomy. The importance of adequate and prompt management of renal failure to expect the spontaneous recanalization is stressed. Because of the high mortality rate associated with the nephrectomy in neonates,...
Original Article
Percutaneous Needle Liver Biopsy in Infancy and Childhood.
Ki Sup Chung, Young Mo Sohn, Duk Jin Yun, Chan Il Park
Clin Exp Pediatr. 1981;24(7):609-619.   Published online July 15, 1981
Thirty percutaneous liver biopsy and one liver necropsy were reviewed in Severance Hospital, Yonsei University from June 1979 to September 1980. This procedure is the safe and accurate means of diagnosing and studying liver diseases in the pediatric patients especially persistent conjugated hyperbilirubinemia, chronic liver disease, and some rare diseases (eg. Histiocytosis-X, Storage disease disease, Gilbert syndrome), The significance of...
Case Report
Hepatorenal Syndrome.
Kyo Sun Kim, Young Mo Sohn, Jung Soo Kim, Jae Seung Lee, Pyung Kil Kim, Tae Jung Kwon, In Jun Choi
Clin Exp Pediatr. 1981;24(3):257-270.   Published online March 15, 1981
Hepatorenal syndrome is generally urged, at least until specific interrelationships between the two organs are confirmed by experimental and clinical data. Case I was a 11 year old boy, who had been suffered from acute fulminant viral hepatitis, which had developed acute hepatic necrosis associated with acute renal failure. Cass H was a 10 year old girl, who was performed corrective...
Original Article
Clinical Obseervation and Changing Patterns of Resistance to Antibiotics in Childhood Shigellosis.
Young Mo Sohn, Kwand Ho Kim, Chang Jun Coe, Pyung Kil Kim, Duk Jin Yun
Clin Exp Pediatr. 1981;24(3):229-234.   Published online March 15, 1981
This paper presents 97 patients of childhood shigellosis which was proved by stool cultures. 44.3% of all patients was accompanied with convulsion. All convulsions were developed under the 6 years of age and associated with high fever. The prognosis was poor in convulsive 容roup. Spinal tapping was performed in 30 patients, in which 3 cases of meningitic type were found....
Case Report
A cases of Congenital Nephrogenic Diabetes Insipidus with Bilateral Hydronprosis.
Young Mo Sohn, Chul Lee, Pyung Kil Kim, Duk Jin Yun
Clin Exp Pediatr. 1980;23(5):417-422.   Published online May 15, 1980
A 13 year old boy was diagnosed as primary nephrotic diabetesinsipidus, whose symptom has been devloped from 3 years of age, subsequetly he developed bilateral hydronephrosis and neurogenic bladder. His pedigree could be explored 5 generations and represented inheritace as X-linked recesslive transmission, He was treated with indomethacin 2mg/Kg/day plus chlorothiazid 500mg/dau and this new method shows markedly decreased urine...
A Case of Nephrotic Syndrome Associated with Distal Type Tubular Acidosis, Nephrocalcinosis and Renal Osteodystrophy.
Young Mo Sohn, Pyung Kil Kim, In Joon Choi, Chang Yun Park
Clin Exp Pediatr. 1980;23(4):321-325.   Published online April 15, 1980
A non-familial type nephrotic syndrome associated with distal renal tubual acidosis, nephrocalcinosis and renal osteodystropy is a very rare disease. A 4 year old boy was treated with prednisone under the impression of minimal lesion nephrotid syndrome but the response was not excellent along with persistant microhematuria in his serial urinalysis. Percutaneous renal biopsy speciman revealed microcalcification around afferent arteriols...
Lupus Nephritis: 2 cases report and literature review.
Hong Kyu Lee, Young Mo Sohn, Soo Hyung Kim, Ki Sub Chung, Phung Kil Kim, Duk Jin Yun, Tai Seung Kim, In Joon Choi
Clin Exp Pediatr. 1979;22(7):538-545.   Published online July 15, 1979
Lupus nephritis is one of complication of systemic lupus erythematous involving many organ systems. And the incidence of renal involvement is about 80%. Principal site of renal injury is glomerulus, and immune complex and complements are deposited in mesangium, basement membrane capillary loops of the glomerulus in lupus nephritis. Histopathologically, 4 distinct forms of renal injury may be seen such...
A Case of Fibrous Dysplasia.
Jung Soo Kim, Young Mo Sohn, Jae Song Kim, Duk Hi Kim, Kyoung Ja Cho
Clin Exp Pediatr. 1979;22(3):234-238.   Published online March 15, 1979
Fibrous dysplasia of bone is a relatively rare condition characterized by fibrous tissue replacement of skeleton, usually not disabling, of slow progress, and showing a tendency to become arrested. It may be monostotic (confined to one bone) or Polyostotic (situated in many bones). The etiology of fibrous dysplasia is unkown but it is now believed to be a developmental error...
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