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Original Article
Limitations of 99mTc-DMSA scan in diagnosing acute pyelonephritis in children
Byung Gee Kim, Jae Ryoung Kwak, Ji Min Park, Ki Soo Pai
Clin Exp Pediatr. 2010;53(3):408-413.   Published online March 15, 2010
Purpose : We aimed to prove the relative limitation of 99mTc-DMSA scintigraphy (DMSA) compared to computed tomography (CT) in diagnosing acute pyelonephritis (APN) in children. Methods : Since September 2006, after a 64-channel CT was imported, 10 DMSA false-negative patients have been identified: these patients underwent a CT scan for acute abdomen or acute febrile symptoms and were diagnosed as...
Case Report
Acute hemorrhagic edema in an infant mimicking Henoch-Sch nlein purpura: a case study
Hyang Mo Lee, Eun Young Kang, Han Uk Kim, Pyoung Han Hwang
Clin Exp Pediatr. 2006;49(12):1354-1357.   Published online December 15, 2006
Acute hemorrhagic edema of infancy (AHEI) is an uncommon form of cutaneous leukocytoclastic vasculitis that occurs in infants and children younger than 2 years. AHEI is characterized clinically by marked peripheral edema and fever as well as large palpable purpuric and ecchymotic skin lesions in a target-like pattern, mainly on the face, ears and extremities, similar to the skin findings...
Review Article
Neonatal skin diseases
Kyu Han Kim
Clin Exp Pediatr. 2006;49(1):1-5.   Published online January 15, 2006
Several physiological skin changes such as vernix caseosa, cutis marmorata, physiologic desquamation, and sebaceous hyperplasia have been described in the neonatal period. There are also clinical characteristics of skin peculiar to neonate and infancy. Skin disorders observed during neonatal and infancy period can be divided into transient skin lesions, birth marks, and other diseases. Transient skin lesions include milia, sebaceous...
Case Report
Melanotic Neuroectodermal Tumor of Infancy in the Epididymis : A Case Report
Sang Bae Lee, Seong Hun Lee, Min Hyuk Ryu, Ji Seoung Park, Joo Heoun Yang, Sun Young Kim, Dong Jean Lee
Clin Exp Pediatr. 2004;47(12):1334-1337.   Published online December 15, 2004
Melanotic neuroectodermal tumor of infancy (MNTI) is a rare neoplasm known by a variety of names including melanotic progonoma and retinal anlage tumor, and currently thought to be neural crest derivation. The vast majority develop within the first year of life. The behavior is generally benign, but recurrent and metastatic cases have been documented. It arises in the head and...
Original Article
Sudden Unexpected Death in Infancy (Analysis of 34 Cases Including 13 Autopsies)
Yeo Ok Moon, Hee Kyoung Choi, Jeoung-A Her, Woo Jong Shin, Myoung-A Kim, Seong Yong Lee, Seong Hee Jang, Eun Sil Dong, Chong Jae Kim, Young Min Ahn, Je Geun Chi
Clin Exp Pediatr. 2002;45(9):1065-1074.   Published online September 15, 2002
Purpose : The purpose of this study is to analyze the epidemiologic characteristics of sudden unexpected death in infancy and to evaluate the importance of postmortem autopsy. Methods : We reviewed, retrospectively, medical records of 34 infants admitted to Kangnam General Hospital from January 1987 to December 2001 because of sudden unexpected death. We investigated the cause of death through medical...
Case Report
A Case of Chronic Pneumonitis of Infancy in Pediatric Interstitial Lung Disease
Hyun Oh Jang, Se Chang Ham, Young Kyoun Kim, Se Wook Oh, Yong Won Park
Clin Exp Pediatr. 2001;44(9):1085-1090.   Published online September 15, 2001
The interstitial lung diseases(ILD) comprises a large, heterogeneous group of disorders characterized by derangement of alveolar walls and alveolar capillary unit causing restrictive pulmonary dysfunction and disordered gas exchange. It is rare, especially in children, and the opinions on investigation and treatments are controversial. The classification of adult ILD is applied to that of children. But considering occurrence during the developing state of lung...
Original Article
Hemorrhagic Shock and Encephalopathy Syndrome as a Cause of Sudden Death in Infants
Jong Won Lee, Chang Han Lee, Ki Sup Chung
Clin Exp Pediatr. 2000;43(6):814-819.   Published online June 15, 2000
Purpose : To evaluate the clinical characteristics, treatments and outcome of patients with hemorrhagic shock and encephalopathy(HSE) syndrome. Methods : We performed a clinical study on 14 patients who were diagnosed as hemorrhagic shock and having encephalopathy syndrome in the Department of Pediatrics, from 1984 to 1998. Age, sex, clinical symptoms and physical findings at admission, the most deranged laboratory findings,...
Medical Therapy in Children with Persistent Hyperinsulinemic Hypoglycemia of Infancy(PHHI)
Hyun-Jeong Kim, Mi-Jeong Kim, Hwa-Sook Shin, Jung-Sim Kim, Mie-Ryung Uhm, Si-Hwan Ko, Suk-Hyang Lee, Dong-Kyu Jin
Clin Exp Pediatr. 2000;43(2):253-259.   Published online February 15, 2000
Purpose : Persistent hyperinsulinemic hypoglycemia of infancy(PHHI), which is characterised by inappropriate insulin secretion in spite of hypoglycemia, needs urgent treatment to prevent cerebral hypoglycemic damage. Although pancreatectomy is the treatment of choice for PHHI, there are several complications which follow treatment. We suggest that aggressive medical therapy, when effective, is preferable to partial pancreatectomy. Methods : We evaluated 8 patients...
Clinical Studies of Intractable Diarrhea During Infancy
Jae Hong Park, Cheol Hong Kim, Eui Jun Yang, Sang Wook Park, Sang Wook Nam
Clin Exp Pediatr. 1998;41(7):923-930.   Published online July 15, 1998
Purpose : Intractable diarrhea during infancy is one of the major causes of infant mortality. But, its etiology, clinical courses, or methods of treatment are not well known. Therefore, we conducted a clinical approach to intractable diarrhea during infancy. Methods : We have retrospectively evaluated clinical characteristics, laboratory findings, methods of treatment, days required for recovery, in 23 infants who were...
Case Report
A Case of Tuberculous Pneumonia in Infancy
Joon-Sung Lee, Young-Yoo Kim, Jong-Wan Kim
Clin Exp Pediatr. 1997;40(4):559-566.   Published online April 15, 1997
A rare but serious complication of tuberculosis in a child occurs when the primary infection is progressively destructive. It is difiicult to differentiate from other bacterial pneumonias. We experienced a case of tuberculous pneumonia in a 73-days-old male who presented with cough, fever and progressive dyspnea. Chest X-ray shows diffuse pneumonic consolidation on right upper lung field, Mantoux test was positive...
Original Article
A Clinical Evaluation of the Esophagogastroduodenoscopy Studies in Infants and Early Children
Won Jung Shin, Jong Won Shin, Young Ho Ahn, Jin Bok Hwang, Chang Ho Han, Hai Lee Jung, Young Dae Kwon
Clin Exp Pediatr. 1996;39(9):1280-1287.   Published online September 15, 1996
Purpose : Even though the causes and appearance of upper gastrointestinal tract lesions vary with age, attention has seldomly been focused on the infancy and early childhood. This study aimed to provide, as basic material, the experience of esophagogastroduodenoscopy(EGD) in infants and early children. Methods : The objects were 66 patients(male 40, female 26) who underwent EGD examination in case of endoscopic indication at department...
A Follow-Up Study of Intractable Diarrhea in Early Infancy: Clinical Features of Cow's Milk Allergy and Cow Milk-Sensitive Enteropathy
Young Rak Kwon, Young Ho Ahn, Jin Bok Hwang, Chang Ho Han, Hai Lee Chung, Young Dae Kwon
Clin Exp Pediatr. 1995;38(11):1515-1524.   Published online November 15, 1995
Purpose : The multiplicity of poorly defined illnesses and the variability of clinical and laboratory features elicited by milk ingestion in sensitized infants has made it difficult to differentiate them from the more common forms of cow milk intolerance. Following up the cases of intractable diarrhea in early infancy(illI), We investigated the clinical features of cow's milk allergy(CMA) and cow...
Intractable Diarrhea in Early Infancy : Clinical Features on Admission and A Nutritional Management
Jong Won Shin, Kyung Won Hwang, Young Ho Ahn, Jin Bok Hwang, Chang Ho Han, Hai Lee Chung, Young Dae Kwon
Clin Exp Pediatr. 1995;38(7):936-945.   Published online July 15, 1995
Purpose : We studied to assess the value of clinical findings on admission in screening of intractable diarrhea in early infancy(IDI) and the efficiency of early trial of semi-elemental form-ula (protein hydrolysate) as a nutritional management in IDI. Methods : We carried out a retrospective review of medical records of twenty-eight early infants with diarrhea and malnutrition who were diagnosed as...
Case Report
2 Cases with Adult Respiratory Distress Syndrome in Infant and Young Child
Hye Jung Joo, Im Jae Park, Joon Soo Lee, Soo Young Lee, Byeung Ju Jeoung, Kyu Earn Kim, Ki Young Lee, Hyunee Yim, Soon Won Hong, Woo Hee Jung
Clin Exp Pediatr. 1992;35(8):1118-1126.   Published online August 15, 1992
Adult respiratory distress syndrome has been described as a clinical syndrome of respiratory distress and need for mechanical ventilation with positive end-expiratory pressure, diffuse pulmonary infiltration on thoracic roentgenogram, impaired pulmonary compliance, decreased lung volumes and capacities, increased alveoloarterial oxygen gradient and hyaline membrane formation. It is the clinical manifestation of injury to the terminal alveolocapillary unit as a result...
Original Article
Detection of antigen of RSV and clinical considerations on epinephrine response in wheezy infancy.
Gui Ran Kim, Seoung Tae Kim, Hyang Suk Hyun, Sang Geel Lee, Im Ju Kang, Sei Yun Jung
Clin Exp Pediatr. 1991;34(3):388-397.   Published online March 31, 1991
Clinical studies were made on 126 cases of wheezing infants, who had been admitted to the department of pediatrics, Fatima Hospital, from June 1988 to May 1989. The nasal discharge of patients were examined for detection of antigen of RSV by ELISA method and then we compared RSV antigen positive group with RSV antigen negative group on aspects of epinephrine response and atopic characteristics. The...
Acute pyogenic arthritis of hip in neonate and infant.
Mi Jung Kim, Young Ah Lee, Young Pyo Chang, Hoan Jong Lee, Jung Hwan Choi, Chong Ku Yun, Hak Jin Min, In Ho Choi
Clin Exp Pediatr. 1991;34(2):197-205.   Published online February 28, 1991
Acute pyogenic arthritis of hip is a serious infection that can lead to truly devastating complica- tions especially in neonatal period and infancy. Clinical survey on twelve neonates and infants (14 hip joints) with acute pyogenic arthritis of hip who were admitted to the Departments of Pediatrics and Orthopedic Surgery, Seoul National University Hospital from Jan. 1980 to Dec. 1989 were done. The results...
Preventive Effect of Single Dose Vitamin K for the Late Hemorrhagic Disease of Infancy.
Young Youn Choi, Hwa Il Kwag, Byung Hee Kim, Tai Ju Hwang
Clin Exp Pediatr. 1990;33(5):606-614.   Published online May 31, 1990
To evaluate the preventive effect of single dose vitamin K for the late hemorrhagic disease of infancy, hepaplastin test was carried out in 15 breast-fed and 12 formula-fed babies. Vitamin Ki lmg was injected immediately after the birth intramuscularly and the test was performed the 1st (before vitamin k administration), 3rd, 7th, 28th days of life and the end of the 2nd and...
Hematologic Reference Values of Peripheral Blood in Healthy Newborns and Infants.
Nam Hyuk Joo, Hong Ja Kang, Soon Ho Kim
Clin Exp Pediatr. 1990;33(4):481-490.   Published online April 30, 1990
To estimate hematologic reference values of the peripheral blood of newnboms and infants, the author examined the routine hematologic parameters by heel or finger puncture in 73 cases of first day newborn, 64 cases of 7 day newborns, 10 cases of 2 month infants, 14 cases of 3~6 month infants and 13 cases of 15~18 month children. The routine hematologic parameters including red cell...
2 Cases of Intracranial Hemorrhae due to Late Hemorrhagic Disease of Infancy due to Vitamin K Deficiency.
Bong Hyune Chung, Hee Jung Seo, Young Hee You, Hyung Sook Lee
Clin Exp Pediatr. 1989;32(12):1726-1731.   Published online December 31, 1989
A clinical study was done on 2 cases under the diagnosis of late hemorrhagic disease of infancy due to Vitamin K dependent factor deficiency. The following results were obtained. The disorder occured most frequently during early infancy (40 days of age & 2 months of age) with male predominance (2 cases all are male). G-I tract, skin, CNS were the most common site...
Three Cases of Late Hemorrhagic Disease of Ingancy.
Yang Su Kang, Ree Sa Lee, Sang Kyn Park, Ho Jin Park, Mi Ja Shin
Clin Exp Pediatr. 1989;32(7):1001-1006.   Published online July 31, 1989
The characteristic features of late hemorrhagic disease of infancy are noraml pregnancy and delivery, no vitamin K prophylaxis at birth, often breast feeding, normal development and good health until the acute bleeding with a high incidence of intracranial hemorrhage. We have experienced 2 cases of intracranial hemorrhage, 1 case of bleeding from injection site due to vitamin K deficiency.
Truncus Arteriosus Associated with Interrupted Aortic Arch.
Chang Hyun Yang, Jae Seung Yang, Jun Hee Sul, Dong Soo Kim, Sung Kyu Lee, Dong Shik Chin
Clin Exp Pediatr. 1988;31(6):779-783.   Published online June 30, 1988
We experienced a case of truncus arteriousus associated with interrupted aortic arch, ventricular septal defect and patent ductus arteriosus. A 5 month old boy had complained of rapid respiration and feeding difficulty since birth. There was no visible cyanosis or clubbing toes and nails. There was a grade 2 〜3 ejection systolic murmur with maximum intensity at the left lower sternal border. Diagnosis was...
6 Cases of Intracranial Hemorrhage due to late Late Hemorrhage Disease of Infancy.
Sang Ho Choi, Jae You Choi, Jee Sung Kim, Im Ju Kang
Clin Exp Pediatr. 1988;31(1):106-112.   Published online January 31, 1988
A bleeding syndrome in early infancy due to vitamin K deficiency has been reported sporadically from various parts of world. The syndrome has similarities to hemorrhagic disease of newborn. The main differences are that it is found in an older age group, the pathogenesis is unknown, and intracranial hemorrhage are frequent with a resultant high mortality rate. We have experienced 6 cases of spontaneous...
Late Hemorrhagic Disease of Infancy.
Kwang Wook Ahn, Chull Zoo Jung, Hyo Seop Ju, Seung Woo Moon
Clin Exp Pediatr. 1986;29(6):679-683.   Published online June 30, 1986
Late hemorrhagic disease of infant is a hemorrhagic disease due to prothrombin complex deficiency from 1 week to 1 year of age. It is hypothesized that the bleeding occurring may have resulted from the simultaneous occurrence of two or three of the following factors: (1) interference with the intestinal production of vit K as a result of Antibiotic Agents, (2)...
Congenital Heart Disease in Neonatal Period and Infancy .
Jung Yun Choi, Hey Sun Lee
Clin Exp Pediatr. 1984;27(6):570-582.   Published online June 30, 1984
From July 1980 to June 1983, total 468 cases of infants of congenital heart disease were studied, who needed intensive care in infancy at Seoul National University Hospital. 1)Among 468 cases, 285 cases were diagnosed by cardiac catheterization or cardiac surgery and the other 183 cases by only clinical base. 2)Relative frequencies of these individual anomalies were in order of...
A Study of the Liver Biopsies in Infancy and Childhood.
Mea Young Chung, Ki Sup Chung, Chan Il Park, Yoo Bock Lee
Clin Exp Pediatr. 1982;25(7):656-668.   Published online July 31, 1982
To investigate the liver diseases affecting infancy and Childhood and to make a clinicopathologic correlation, a total of 105 liver biopsies were examined and following results were obtained. 1. Of the 105 liver biopsies, 94 cases were available for the study, and the male to female ratio of liver biopsies in infancy and childhood was 1.8 : 1. 2. Of...
Case Report
Five Cases of Hemorrhagic Disease of Infancy.
Jung Sook Moon, Eun Hee Koh, Sang Man Shin, Sang Jhoo Lee
Clin Exp Pediatr. 1982;25(5):518-522.   Published online May 31, 1982
A hemorrhagic disease due to acquired prothrombin complex deficiency is presented in five infants from 3 weeks to 2 months of age. There are 2 cases of intracranial hemorrhage, 1 case of hemothorax, 2 cases of gastrointestinal bleeding, 1 case of epistaxis and 3 cases of petechia, purpura or bleeding from injection site. After the administration of vitamin K, bleeding...
Original Article
Late Hemorrhagic Disease of Infancy due to Vitamin K Dependent Factor Deficiency.
Kang Il Lee, Yong Soon Kim, Sang Bum Lee, Ja Hoon Koo
Clin Exp Pediatr. 1982;25(1):52-57.   Published online January 31, 1982
A clinical study was done on 9 children with 10 episodes, who were admitted to our pediatric ward under the diagnosis of late hemorrhagic disease of infancy due to vitamin K dependent factor deficiency. Study period was past 2 years, from September 1979 to May 1981. The following results were obtained. This disorder occurred most frequently during early infancy, with...