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Case Report
A Case of Eosinophilic Cystitis in Child
So Young Park, Seung Joo Lee
Clin Exp Pediatr. 1995;38(8):1155-1159.   Published online August 15, 1995
Since Brown first descirbed the eosinophilic granuloma in 1960, 45 cases of eosinophilic cystitis have been reported in the literature, including 10 pediatric cases. In Korea, only four adult cases were reported. Eosinophilic cystitis is characterized by severe infiltration o eosinophils into the mucosa, submucosa and muscularis of bladder wall which causes irritative voiding symptoms. This lesions have been frequently...
Original Article
A Survey on the Present Status of Infant Feeding
Seung Joo Lee, Jae Ok Park, Chang Sung Sohn, Hae Ran Lee, Jae Hoon Shin, Hae Il Chung, Seung Il Kim
Clin Exp Pediatr. 1994;37(12):1657-1668.   Published online December 15, 1994
A Survey on the Present Status of Weaning
Seung Joo Lee, Jae Ok Park, Chang Sung Sohn, Hae Ran Lee, Jae Hoon Shin, Hae Il Chung, Seung Il Kim
Clin Exp Pediatr. 1994;37(12):1643-1656.   Published online December 15, 1994
Purpose : To add proper solid food during the ideal weaning period is very important to supply adequate nutrition for the rapid growt and to achieve proper feeding habits in later infancy. We tried to survey the problems in weaning in Korea. Methods : The Present status of infant weaning was sutneyed 6 university hospital in Seoul and 4 rural goverment...
Effect of Perinatal Asphyxia and Gentamicin on Urinary β2-microglobulin Concentration and Renal Function in Fullterm Neonates
Hoo Jae Hann, Seung Joo Lee
Clin Exp Pediatr. 1994;37(7):976-985.   Published online July 15, 1994
Perinatal asphyxia can cause ischemic injury to immature kidney of neonates. Proximal renal tubule is the most sensitive area, showing various manifestations ranging from mild reversible injury to irreversible tubular necrosis. Aminoglycosides can be nephrotoxic in therapeutic range in immature or damaged kidney. These are the very important factors to be taken into corsideration on fluid therapy and nephrotoxic drugs...
Hypercalciuria in High Risk Neonate
Eun Sun Kim, Seung Joo Lee
Clin Exp Pediatr. 1994;37(3):322-331.   Published online March 15, 1994
The incidence and risk factors for hypercalciuria were studied in 23 sick preterm (Group I), 36 well preterm (Group II), 16 sick term (Group III) and 41 well term (Group IV) neonates who were admitted to NICU and nursery of Whwa Woman's University Hospital from May 1988 to February 1992. The results were as follows: 1) The incidences of hypercalciuria were 73.9%...
Case Report
Two Case of Psedohypoaldosteronism Type 1
Ji Eun Lee, Jung Wan Seo, Seung Joo Lee
Clin Exp Pediatr. 1994;37(1):122-128.   Published online January 15, 1994
Pseudohypoaldosteronism type 1 is a genetic renal tubular disease of salt wasting, presenting in young infants. Tubular unresponsiveness to elevated endogenous an exogenou aldosterone is the suggested pathogenetic mechanism. Oral sodium chloride supplementation relieve the clinical symptoms and electrolyte distrubances. We experienced 2 cases of PHA type 1 in 38-day and 450day old male infants who were presented with failure to...
Original Article
Screening of urinary Tract Infection in High-Risk Neonates
Hyeon Joo Choi, Seung Joo Lee
Clin Exp Pediatr. 1992;35(12):1683-1679.   Published online December 15, 1992
Since the urinary tract infection (UTI) in neonates is often associated with major urologic anomalies, early diagnosis is essential. In the screening of UTI by urine bag, contamination is a commonly encountered problem. Suprapubic bladder puncture has therefore been recommended as the best method to confirm UTI. The purpose of this study is to assess the frequency and characteristics of...
Urinary Tract Infection and Neonatal Circumcision
Seung Joo Lee
Clin Exp Pediatr. 1992;35(8):1035-1043.   Published online August 15, 1992
An association between urinary tract infection in male infants and uncircumcised status has been suggested recently. Male predominance of UTI in most reports in Korea may be related to this uncircumcised status. The present study was prospectively performed between Mar. 1989 and May. 1991 to investigate this relationship and the effect of neonatal circumcision on the intraurethral bacterial flora. 1) The...
Case Report
Adult Respiratory Distress Syndrome in Infancy
Hoo Jae Hann, Young Mi Hong, Seung Joo Lee
Clin Exp Pediatr. 1992;35(2):245-251.   Published online February 15, 1992
Adult Respiratory distress Syndrome (ARDS) is a clinical entity characterized by respiratory distress and diffuse pulmonary infiltrates due to increased permeability after various kinds of insult to alveolar-capillary membrane. We experienced a case of ARDS in a 3-1/2 month old girl after Pseudomonas pneumonia, cardiac arrest and generalized convulsion. This is the report on her clincal and autopsy findings with brief review...
Original Article
The effect of ultrasonic nebulized salbutamol in the first attacked wheezy infants.
Soo Young Kweon, Young Mi Hong, Gyung Hee Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1991;34(11):1505-1511.   Published online November 30, 1991
Wheezing is one of the most common symptom in the first 2 year of life. Although the effect of bronchodilator in wheezy infants was still debating, various form of bronchodilator has been tried untill now. This study was done to estimate the value of ultrasonic nebulized salbutamol as a bronchodilator test and maintenance therapy compared to epinephrine and aminophylline in 44 wheezy infants below 24...
Early detection of gentamicin nephrotoxicity using urinary beta2-microglobulin in neonates.
Mi Kyung Kim, Seung Joo Lee
Clin Exp Pediatr. 1991;34(7):940-948.   Published online July 31, 1991
Gentamicin, commonly used antibiotics in neonatal care, has a nephrotoxicity, but it is difficulto to assess renal function in early stage. This study evaluated the renal function and urinary β2-microglobulin excretion in 17 gentamicin treated and 11 control neonates. The results are as follows. 1) Urinary 02-M in gentamicin treated neonates were 0.84±0.17mg/L at postnatal day 1 and increased to 5.99±1.15mg/L at day 4, 14.17±2.39mg/L at day...
A Case of Acute Mixed Lineage Leukemia (ANLL with TII) with neutropenic Enterocolitis.
Hyeon Joo Choi, Young Suk Koh, Young Mee Hong, Seung Joo Lee, Kee Suk Hong, Keum Ja Choi
Clin Exp Pediatr. 1990;33(9):1281-1287.   Published online September 30, 1990
We report a case of acute mixed lineage leukemia with both lymphoid and myeloid lineage characteristics (ANLL with Til) in a twelve-year-old girl who presented with fever and multiple petechiae. Bone marrow remission was obtained by treatment with acute lymphoid leukemia regiman (CCSG 106A). During induction chemotherapy, the patient was complicated by intestinal perforation due to neutropenic enterocolitis but recovered by surgical intervention and...
The Change of Anti-HBs Titer after Hepatitis B Vaccination in Newborn.
Ji Hye Kang, Young Mi Hong, Seung Joo Lee
Clin Exp Pediatr. 1990;33(5):598-605.   Published online May 31, 1990
Hepatitis B vaccination is an accepted preventive measure for all newborn as well as the risk group. However, there is some uncertainty about the persistence of anti-HBs and the timing of booster vaccination. We studied anti-HBs titer, positive rate and minimum protective rate in relation to time interval after the third vaccination in 102 infants bom to HBsAg negative mother (Group I) and 52...
A Case of Transient Myeloproliferative Disorder in Down's Syndrome.
Ji Hye Kang, Young Mi Hong, Kyung Hee Kim, Seung Joo Lee, Ki Sook Hong, Ok Kyung Kim, Je Geun Chi
Clin Exp Pediatr. 1990;33(2):252-258.   Published online February 28, 1990
Transient myeloproliferative disorder has been reported in infant with Down's syndrome during neonatal period. This is clinically and hematologically indistinguishable from congenital acute leukemia. In contrast to congenital leukemia, complete clinical and hematological recovery occurs within weeks to months of diagnosis without antileukemic treatment. A neonate presented with jaundice, hepatosplenomegaly and mongoloid face was diagnosed as Transient myeloproliferative disorder. We report this case with a review of...
A Study on Anemia of Acute Infectious Disease in Children.
Hae Won Lee, Young Mi Hong, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1990;33(1):75-80.   Published online January 31, 1990
The anemia of acute infectious disease has come to attention recently, since iron deficiency anemia has decreased. We screened for anemia in children admitted to Ewha Womans University Hospital due to acute infectious disease between January 1, 1986 and July 31, 1988, and studied the incidence and characteristics of anemia in acute infectious diseases. The result were as follows: 1) The incidence of anemia in acute...
Clinical Strudy of chlamydial Pneumonia in Early Infants.
Mi Kyung Kim, Young Mi Hong, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1990;33(1):51-58.   Published online January 31, 1990
We studied Chlamydiazyme test in 55 infants below 6 months of age with lower respiratory tract infection, admitted to the Pediatric ward of Ewha Womans University Hospital, between October 1, 1987 and February 28, 1989. The results were as follows. 1. The overall incidence of Chlamydial pneumonia was 14,5% (8/55). All of them were below 2 months of age, so the incidence in infants below...
A case of Guillain-Barré syndrome in a child treated with plasmapheresis.
Hae Won Lee, Hoo Jae Han, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1989;32(11):1592-1597.   Published online November 30, 1989
We experienced a case of Guillain -Barré syndrome in a 12-year-old female patient who had progressive motor weakness and showed rapid recovery with plasmapheresis and supportive therapy in acute stage. A brief review of the related literature was added.
A case of Idiopathic Crescentic Glomerulonephritis.
Mi Kyung Kim, Hyun Joo Choi, Seung Joo Lee, Ok Kyung Kim
Clin Exp Pediatr. 1989;32(10):1435-1441.   Published online October 31, 1989
Idiopathic crescentic glomerulonephritis is a very rare disease especially in children with poor prognosis. We experienced a case of idiopathic crescentic glomerulonephritis in a 4-year-old male patient who presented initially with a nephrotic syndrome and progressed to a rapidly progressive glomerulonephritis. We review literatures briefly.
Idiopathic Hypercalciuria in Children.
Kyung Ha Ryu, Seung Joo Lee, Keun Lee, Jae Sun Jung
Clin Exp Pediatr. 1989;32(6):809-815.   Published online June 30, 1989
Idiopathic hypercalciuria is defined as increased urinary excretion of calcium in normocalcemia without primary cause. It is associated with urinary symptoms, such as hematuria but it occurs without any symptoms too. If left untreated, it may cause kidney stone, dimineralization of bone, or other problem. The incidence of idiopathic hypercalciuria was 3.9% in asymptomatic group compared to 5% in unselected populations in this study....
Primary Vesicourteral Reflux in Children.
Seong Hee Choi, Seung Joo Lee
Clin Exp Pediatr. 1989;32(4):542-549.   Published online April 30, 1989
The primary vesicourteral reflux is the reflux of urine from the bladder to ureter and renal pelvis due to congenital incompetence of valvular mechanism at the ureterovesical junction. It can result in the development of renal scars(reflux nephropathy), particularly in association with urinary tract infection and intrarenal reflux. The authors studied 21 patients with primary vesicourteral reflux who were admitted to department of...
PPD Conversion Rate and Complications According to the Different Time of BCG Vaccination.
Kyung Hyo Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(5):487-490.   Published online May 31, 1987
BCG vaccination shortly after birth has shown to protect against tuberculosis in some studies. PPD conversion rate and complications were compared between 174 neonates who received BCG vaccine within 1 week after birth and 330 infants who received BCG vaccine at the 1 month of age. The results were as follows: 1) The PPD conversion rate was 20.11% in the neonates who received vaccine within...
A Prospective Study ot Neonatal Acute Renal Failure: The Significance of Various Diagnostic Indices.
Kyung Hyo Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(4):378-384.   Published online April 30, 1987
Acute renal failure is defined as a sudden decrease in renal function resulting in progressive retention of nitrogenous waste products. Acute renal failure should be suspected in any infant who has a sustained decrease in urine output to less than 1 ml per kg per hour, a blood urea nitrogen level above 20 mg per dl, a serum creatinine level greater than 1.0...
The Study of Creatinine Clearance in Neonates.
Dong Sun Hong, Moon Ja Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(2):139-143.   Published online February 28, 1987
The creatinine clearance rate, an index of glomerular filtration rate, has been reported to develop according to gestational and postnatal age. The purpose of this study is to examine changes in creatinine clearance with gestational age and postnatal age in preterm and full term healthy neonates. The results were as follows: 1) The creatinine clearance rate increased according to gestational age. 2) The most in creament of creatinine...
Sodium Homeostasis by Neonatal Kidney.
Seung Joo Lee
Clin Exp Pediatr. 1987;30(1):17-25.   Published online January 31, 1987
Sodium homeostasis by neonatal kidney is important during the postnatal adaptation of body fluid. It is mainly dependent to renal function which was differently maturated by gestational and postnatal ages. I studied the postnatal changes of daily Na intake, urine Na, Na balance, FEN a and Serum Na concentration in neonates with different gestational age. In this study, I demonstrated that more increased urinary...
Postnatal Changes of Serum Creatinine Levels in Neonates.
Jeong Wan Seo, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1986;29(9):948-953.   Published online September 30, 1986
The concentration of creatinine, one of the simple and commonly used indices of glomerular filtration rate in children and adults, has been reported to be appreciably raised and variable during the first month of life. This study examined the effect of gestational age(G.A.) on the postnatal changes of creatinine in preterm and full-term neonates. The results were as follows; 1) The mean...
The Effect of Intravenous Dextrose Water Given to Mother During Labor on Sodium Concentration of Maternal and Cord Serum.
Soo Kyung Chung, Dong Suk Suh, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1986;29(8):840-844.   Published online August 31, 1986
We studied the influence of intravenous electrolyte-free dextrose solution given to the mother during labor on the change of maternal and cord serum concentrations and the incidence of hyponatremia in 109 mothers and their newborns. 1) Na+ concentrations of maternal and cord serum in study group given intravenous electrolyte free dextrose solutions were 134.57土2.43 and 134.54±2.95, which was significantly lower,...
Effects of Antenatal Indomethacin on Neonate.
Ja Ye Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1985;28(11):1066-1072.   Published online November 30, 1985
Prostaglandins play an important role in mediating uterine contractions and thus may also be involved in the triggering of premature labor and spontaneous abortion. Consequently inhibition of prostaglandin synthesis has been suggested as a potential means of inhibiting premature labor. There are many controlled studies which have described the use of indomethacin for inhibition of premature labor with success. But...
Serum IgE Levels and Incidence of Atopic Disease according to Infant Diet.
Jeong Wan Seo, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1985;28(8):751-755.   Published online August 31, 1985
The role of breast feeding and dietary elimination of cow's milk as a mean of preventing atopic disease in infants remains controversial. From May 1983 to August 1984，the relationships between the type of feeding in early infancy and incidence of atopic disease were studied in 238 babies of less than 3 years of age and their serum IgE levels were compared....
Case Report
A case of Idiopathic pulmonary hemosideroisis.
Yeong Hee Kim, Jeong Hee Lee, Seung Joo Lee, Keun Lee, Ok Kyung Kim, Doo Yeon Lee
Clin Exp Pediatr. 1985;28(2):182-186.   Published online February 28, 1985
Idiopathic Pulmonary Hemosiderosis is a rare disease characterized by recurrent attacks of hemoptysis, iron deficiency anemia and pulmonary infiltration on chest X-ray. We experienced a case of Idiopathic Pulmonary Hemosiderosis in a 3 year-old boy with recurrent attacks of dyspnea, pallor and chest infiltration on X-ray, without underlying pulmonary disease. Diagnosis was established by hemosiderin and hemosiderin-laden macrophage on lung...
A Case of Clinical Botulism.
Yuoug Suk Ko, Jung Hee Lee, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1984;27(12):1223-1226.   Published online December 31, 1984
A 5-year-old girl was admi竹ed to the department of Pediatrics, Ewha Womans University Hospital on October 21th, 1983 with weakness and lethargy of 5 days duration. Her younger brother expired on the same day aftsr 1 day illness of the same symptoms, and there was a other children who died following similar clinical course in the same area. Even though the diagnosis of botulism...