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Volume 34(8); Aug 1991
Original Articles
Morphological study on the development of human fetal kidney.
Hee Young Shin, Kwang Wook Ko, Je Geun Chi
J Korean Pediatr Soc. 1991;34(8):1045-1056.   Published online August 31, 1991
A total of 293 human fetal kidneys, including those of 42 embryos are studied for the elucidation of temporal development of the kidney. These specimens were interpreted as normal by thorough postmortem examinations. The age of the specimens was determined by developmental horizon criteria in embryos and by correlating crown-rump length in fetuses. Embryos were embedded in toto, cut in various planes and reconstructed...
Weight and morphologic development of prenatal human thymus.
Il Soo Ha, Kwang Wook Ko, Je Geun Chi
J Korean Pediatr Soc. 1991;34(8):1057-1069.   Published online August 31, 1991
Thymus is a primary lymphoid organ which has an important role in maturation of immune competence. This organ matures earlier than the other organs, and the informations about its prenatal development are essential to understand the maturation of human immunity. To delineate the weight and morphologic development of prenatal thymus, the authors measured the weight of 221, and observed gross and histologic features of...
Production and characterization of monoclonal antibodies against human albumin.
Ja Wook Koo, Dong Kyu Jin, Yong Choi, Kwang Wook Ko, Suhnggwon Kim, Jung Sang Lee, Chung Gyu Park, Chang Yong Cha
J Korean Pediatr Soc. 1991;34(8):1070-1079.   Published online August 31, 1991
Hybridoma technology를 이용하여 human albumin에 선택적으로 반응하는 4 종류의 단세포군 항 처 1(HSA-1，HSA-2, HSA-3, HSA-4) 를 개발하였다. 단세포군의 isotype 및 subclass를 효소 결합 면역 측정법으로 검색한 결과 IgGi 이었다. 단세포군 항체 HSA-1 을 제외한 HSA-2, HSA-3, HSA-4 모두 human albumin에 선택적으로 반 응함을 효소 결합면역 측정 법과 Western blot immunoassay로 알아내 었다. HSA-1, HSA-2, HSA-3는 albumin의 reduction 여부와 관계 없이 albumin molecule과 반응하였 으나，HSA-4는 albumin을 reduction하지...
Seroconversion rate of measles specific IgG antibody in previously vaccinated children.
Kyeoing Hun Cha, Eun Kyeong Jung, Kyung Rae Moon, Kap Seung Kim, Sang Kee Park, Yeong Bong Park
J Korean Pediatr Soc. 1991;34(8):1080-1085.   Published online August 31, 1991
This study was performed to evaluate the changes of measles specific IgG antibody titer using enzyme linked immunosorbent assay (ELISA) on the sera of various groups of age. We obtained the following result: 1) Out of 118cases, 99cases (83.9%) were vaccinated children and 19cases (16.1%) were unvac- cinated children. Among them, the number of cases who had been infected with measles were 17 cases (17.2%) in...
The relationship between diuresis and pulmonary function in respira- tory distress syndrome of the newborn.
Eun Ae Park, Yung Sook Ko, Gyoung Hee Kim
J Korean Pediatr Soc. 1991;34(8):1086-1092.   Published online August 31, 1991
The purpose of this study was to determine the relationship between improvement of pulmonary, function and diuresis in respiratory distress syndrome. This study was based on 24 cases of RDS infants admitted in NICU of Ewha Womans University from January 1988 to December 1990. The results were as follows. 1) Mean birth weight of study cases was 2.11 kg with gestational age between 29〜39 weeks. 2) Maximum...
A clinical study of pneumonia presented with positive cold agglutin- in test.
Il Jung Joo, Jin Seop Juong, Sang Woo Kim
J Korean Pediatr Soc. 1991;34(8):1093-1101.   Published online August 31, 1991
A clinical study was performed on 65 patients with Mycoplasma pneumoniae pneumonia who were admitted to the Department of Pediatrics of Seoul Paik hospital from September 1,1989 to August 31, 1990. The results were as follows; 1) Seasonal distribution showed a high frequency in summer (33 cases; 50.8%). 2) The peak incidence was 5 to 9 years of age (32cases;49.2%). 3) Male to female ratio was 1:1.17(30:35). 4) On the chest...
The diagnosis of mycoplasma pneumoniae pneumonia by high density composite particles agglutinin test.
Hae Jin Choeh, Jung Hae Park, Chong Sung Chung, Kyu Chul Choeh
J Korean Pediatr Soc. 1991;34(8):1102-1109.   Published online August 31, 1991
In a prospective investigation of 21 chi Idem 3 years of age or more with Mycoplasma pneumoniae pneumonia, we analyzed the diagnostic efficacy of High Density Composite Particles Agglutinin(HDDA) test comparing with cold agglutinin tests and clinical findings. The results obtained were as followed. 1) Among 24 total cases, the number of cases showing positive reaction to HDPA and to cold agglutination test were 17 and...
Clinical effects of recombinant Korean growth hormone (LBD-003).
Duk Hi Kim
J Korean Pediatr Soc. 1991;34(8):1110-1115.   Published online August 31, 1991
LBD-003, methionyl GH, has been produced recently in the yeast by the use of recombinant method. The clinical efficacy and immunogenecity of LBD-003 were studied in 20 patients with naive GH deficiency. The subjects of this study were aged 5.1—13.9 years and received GH 1.5IU/kg thrice weekly for 1 year. During treatment, height, body weight & bone age were checked. Blood count, chemistry amd thyroid...
A clinical study on the thyroid nodule in childhood.
Yong Ju Kim, Ki Young Cheong, Jong Jin Seo, Young Hun Chung
J Korean Pediatr Soc. 1991;34(8):1116-1122.   Published online August 31, 1991
A clinical study was carried out in 27 children with thyroid nodule who visited the Dept, of pediatrics, Chungnam National University Hospital during the 4 year period from March 1986 to February 1990. The results are as follows; 1) The most frequent age group was between 10 to 15 year, and the mean age was 10.65 ±3.19 year. The male to female ratio was 1:4.4 2) All patients...
Clinical observation on juvenile theumatoid arthritis.
Sung Sub Shim, Chan Yung Kim
J Korean Pediatr Soc. 1991;34(8):1123-1131.   Published online August 31, 1991
The authors analyzed the clinical features, and the therapeutic responses in 29 patients with juvenile rheumatoid arthritis who were diagnosed and followed at Department of Pediatrics, Pusan National University Hospital from 1980. 1 to 1990. 6. The following results were obtained 1) Of the total 29 patients, 12cases (41.4%) were pauciarticular type II and 7cases (24.2%) were polyarticular RF(—) type. Seventeen cases (58.7%) were 8-11 yrs...
A case of idiopathic precocious puberty treated with a luteinizing hormone relaeasing hormone analog.
Keun Hee Chung, Yoo Mi Kim, Mi Won Kim, Soon Ki Kim, Moon Soo Park, Jin Keun Chang
J Korean Pediatr Soc. 1991;34(8):1132-1138.   Published online August 31, 1991
We experienced a 4 year girl with idiopathic precocious puberty treated with a long acting LHRH analog (Buserelin). As an indction therapy she received LHRH analog for 6 months in subcutaneous route. After then she was maintained by intranasal therapy for 6 months. One month after the induction therapy began, we observed prepunbertal pattern of LHRH stimulation test and significant suppression of 17B-estradiol level....
Tricuspid atresia associated with double orifice mitral valve and coronary sinus septal defect.
In Sook Park, Ki Soo Kim, Young Seo Park, Chang Yee Hong, Shi Joon Yoo, Meong Gun Song
J Korean Pediatr Soc. 1991;34(8):1139-1145.   Published online August 31, 1991
Clinical, echocardiographic and angiographic findings of a very rare case of cardiac malformation is presented. The main features were tricuspid atresia, coronary sinus septal defect, and double orifice mitral valve. These defects were correctly diagnosed by echocardiography and were confirmed by angiocardiography. This patient was palliated successfully with blade balloon atrial septostomy and bidirectional cavopulmonary shunt. To the best of our knowledge, this is the...
A case of Rubinstein-Taybi syndrome.
Cheol Hee Hwang, Dong Gue Lee, Myung Sug Nam, Moon Kee Cho
J Korean Pediatr Soc. 1991;34(8):1146-1150.   Published online August 31, 1991
Rubinstein-taybi syndrome is characterized by typical skeletal abnormalities such as broad thumb and large first toe, mental and motor retardation, and facial abnormalities. In addition, defects of the cardiovascular system and the urinary tract may be present. We have experienced a case of Rubinstein-Taybi syndrome which a five-year-old boy had broad thumb and large first toe, mental and motor retardation, and facial abnormaiities (palpebral...
Two cases of Gaucher disease in brother and sister.
Yong Ju Kim, Ki Young Cheong, Jong Jin Seo, Keon Su Rhee, Young Hun Chung, Seon Hoe Koo
J Korean Pediatr Soc. 1991;34(8):1151-1156.   Published online August 31, 1991
We experienced two cases of Gaucher disease in brother and sister. The first case of 6 year old female showed hepatosplenomegaly with thrombocytopenia and characteristic Gaucher cells in bone marrow aspiration and biopsy. She is alive without complaints except abdominal distension. The second case of 3 year ~ 7 month old male showed hepatosplenomegaly with anemia and throm- bocytopenia. There were characteristic Gaucher cells...
A case of Weber-Christian disease.
Doo Kweon Kim, Sang Jo Park, Tae Gyu Whang, Soon Yong Lee
J Korean Pediatr Soc. 1991;34(8):1157-1162.   Published online August 31, 1991
Weber-Christian disease is a relapsing febrile nodular nonsuppurative inflammation of the subcuta- neous fat tissue. We experianced a case of Weber-Christian disease. The patient was a 10-year-old girl with the complaints of fever, malaise and erythematous painful nodules on extremities, trunk and back. The diagnosis was based on the clinical pictures and the histologic findings. Oral prednisolone therapy was tried and the response occurred...
A case of bone marrow necrosis in acute lymphoblastic leukemia.
Mee Ran Kim, Hye Lim Jung, Hong Hoe Koo, Hee Young Shin, Hyo Seop Ahn
J Korean Pediatr Soc. 1991;34(8):1163-1168.   Published online August 31, 1991
Bone marrow necrosis is a rare complication most commonly encountered in patients with leuke- mia, metastatic tumor in marrow, sickle cell disease, DIC and severe infections. Recently it is regarded as a more common finding frequently overlooked and carrying not so poor prognosis. We reported here a boy with ALL who showed marrow necrosis on biopsy at the time of diagnosis and achieved complete...
A case of Addison's disease.
Cheol Hee Hwang, Dong Kui Lee, Myung Sug Nam, Mun Ki Cho
J Korean Pediatr Soc. 1991;34(8):1169-1174.   Published online August 31, 1991
Addison’s disease is a rare disorder resulting from progressive adrenocortical destruction regardless of the nature of underlying process. A 5-year-old boy with Addison’s disease without other endocrine disorder presented with a brief review of the literature. The patient was admitted to out hospital because of poor appetite and generalized darkish brown pigmentation of skin and mucous membrane. On physical examination, skin and mucous membrane were...