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Original Article
Serum IgE Levels in Bronchiolitis Patients.
Seong Hee Choi, Keun Lee
Clin Exp Pediatr. 1989;32(6):749-755.   Published online June 30, 1989
Bronchiolitis is a virus.caused lower respiratory disease resulting from inflammatory obstruction of the small airways. The condition may develop to asthma anddifferential diagnosis is not clearcut between two diseases during infancy. Measurement of the serum IgE concentration has been used as an aid in the differential diagnosis. The purpose of this study is to compare the serum IgE levels between control groups and bronchiolitis patients,...
Psychosocial Screening of Childhood Asthmatic Parient by PSC(Pediatric Symptom Checklist).
Hye Hyun Kim, Keun Lee
Clin Exp Pediatr. 1989;32(5):670-677.   Published online May 31, 1989
It has been accepted that psychosocial difficuties are frequently associated with asthma of childhood, as etiologic factor and/or consequence of the disease. Management of these psychosocial problems has great impact on the course of asthma and early finding of the problems has been strongly advocated. The purpose of this study was to evaluate psychosocial functioning of asthmatic patients and compare them with other groups...
Predictive Capacity of Cord Serum IgE for Developement of Atopy.
Hye Ran Byun, Hye Won Lee, Keun Lee
Clin Exp Pediatr. 1989;32(3):390-395.   Published online March 31, 1989
The incidence of atopic disease has increased in recent years and its symptom begins early in life, in many cases during the first year. It is desirable, therefore, to predict the development of atopic disease early in infancy, preferably in neonatal period, so that it can be prevented or, at least, lessened in symptoms by proper management. One hundred and two fullterm newborn...
Urinary Tract Infection in Febrile Infants.
Jung Soon Whang, Seung Hee Choi, Seong Joo Lee, Keun Lee
Clin Exp Pediatr. 1989;32(1):45-51.   Published online January 31, 1989
Uninary tract infection as one of the common infectious disease all through the childhood and can be the cause of febrile illnesses. During infancy, the diagnosis of UTI is easily overooked because of relative lack of charateristic urinary symptoms. But UTI was found to cause longterm sequelae more often in infancy than later. We studied 258 cases of febrile infants and 345 cases of...
A Study on Coagulopathy in High-risk Neonates.
Chae Sup Yoo, H. W. Lee, Keun Lee, Moon Ja Kim
Clin Exp Pediatr. 1988;31(11):1445-1452.   Published online November 30, 1988
Life threatening neonatal hemorrhage is a common problem in Nursery Intensive Care Unit. It is associated with asphyxia, intracranial hemorrhage, and hyaline membrane disease, and develops to D.I.C., which attributes to neonatal mortality and morbidity. Clinical study was performed on 32 high-risk neonates and 20 mild illness cases, who had been admitted to Department of Pediatrics, Ewha University Hospital, during the period of 2.6...
A Study of Meconium Aspiration Syndrome.
Chae Sup Yoo, Mee Kyung Kim, Keun Lee, Jae Sun Jung
Clin Exp Pediatr. 1988;31(11):1425-1431.   Published online November 30, 1988
The authors observed 51 cases of meconium aspiration syndrome in newborns who were bom at Ewha Womans University Hospital during the period of January 1986 through May, 1987. The results are summarized as follows: 1) The incidence of meconium aspiration syndrome was 1.6% (51 cases). 2) There was a significantly greater incidence of developing meconium aspiration syndrome in meconium stained babies who had toxemia mothers and low...
A Case of Transient Neonatal Diabetes Mellitus.
Hye Hyun Kim, Kyung Ha Ryu, Keun Lee
Clin Exp Pediatr. 1988;31(10):1346-1349.   Published online October 31, 1988
Transient Neonatal D.M. is rare disease which is characterized by letharginess, dehydration and weight loss with severe hyperglycemia. It occurs frequently which small for data infant and recovers spontaneously if appropriate insulin treatment was taken. We had expirienced a case of Transient Neonatal D.M. in 15 days old female infant. The review of the literature was made briefly.
ABO Gene Frequency in ABO Hemolytic Disease of Newborn.
Young Mi Hong, Keun Lee
Clin Exp Pediatr. 1988;31(9):1105-1113.   Published online September 30, 1988
ABO hemolytic disease in newborn due to ABO incompatibility between mother and infant is one of common cause of neonatal hyperbilirubinemia and early detection has been emphasized due to its possible neurologic sequelae. Many studies reported prevalence difference of ABO hemolytic disease in various races, which could be ascribed to different frequency of ABO genes in races. From Feb. 1986 to May 1987 full...
A Case of Acute Megakaryoblastic Leukemia in Infant with Down's Syndrome.
Jung Soon Whang, Soon hee Kim, Moon Ja Kim, Keun Lee, Je Geun Chi
Clin Exp Pediatr. 1988;31(8):1064-1070.   Published online August 31, 1988
Acute megakaryoblastic leukemia is an uncommonly recognized disorder that is characterized by rapidly progressive proliferation of atypical megakaryocytes and their precursor cells, and fatal course. Abnormalities in chromosome 21 may have a more than random relationship to acute megakaryoblastic leukemia. The authors reports a case of acute megakaryoblastic leukemia in a 2 month old female patient who was admitted for evaluation of hepatosplenomgaly. Multiple organ infiltration...
A Case of Pulmonary Candidiasis.
Hye Ran Byun, Kung Ha Ryu, Moon Ja Kim, Keun Lee, Yeon Lim Suh, Je Geun Chi
Clin Exp Pediatr. 1988;31(5):621-626.   Published online May 31, 1988
A case of fatal pulmonary candidiasis was diagnosed at autopsy of 5-month-old female infant. Patient had mild coughing, poor weight gain and marked hepatosplenomegaly. She had no sign of immune dysfunction but developed fever, wheezing and intermittent respiratory distress. Chest P-A showed infiltrations of multiple lobar pneumonia. Postmortem examination revealed the whitish necrotic mass like lesion with a feature of lobar pneumonic consolidation in...
Gastroesophageal Reflux in Ingants and Clinical Experience with 24-Hour Esophageal pH Monitoring.
Kum Ja Choi, Keun Lee
Clin Exp Pediatr. 1988;31(4):427-435.   Published online April 30, 1988
Gastroesophageal reflux defined as a dysfunction of the distal esophagus is a major cause of recurrent vomiting and failure to thrive in newborns and young infants. In infants, the differentiation between pathologic, pernicous vomiting and normal “burping” with regurgitation has been difficult until the far advanced complications of weight loss, failure to thrive, anemia from ulcerating esophagitis, or stricutre have been obvious. A number of...
Survey on Pediatrician's Reactions in Management of Terminal Patients.
Keun Lee
Clin Exp Pediatr. 1988;31(2):227-233.   Published online February 28, 1988
To evaluate the emothional reactions and problems of pediatricians who treat the terminally ill patients, the pediatric staffs and residents in 56 traning hospitals were surveyed with a questionnaire. Total of 331 responded and the results of data were analyzed: 1) There were more males (62.7%) than females (37.3%) and the majority was residents in training (76.6%). 2) 36.6% of respondents took care of one to 10...
Neonatal Hyperbilirubinemia due to ABO Incompatibility.
Kyung Ha Ryu, Hye Ran Byun, Soon Hee Kim, Keun Lee, Moon Ja Kim
Clin Exp Pediatr. 1988;31(2):196-201.   Published online February 28, 1988
Neonatal Hyperbilirubinemia due to ABO Incompatibility was contributed to Kemicterus in our country. We studied the difference between ABO compatible group and incompatible group, such as, day of appearance of Hyperbilirubinemia, tendency of bilirubin concentration change, reticulocyte, hemoglo- bin, and duration of Hyperbilirubinemia. As a result, clinical symptoms were more severe in incom- patible group rather than compatible group. And so, we stress to early diagnosis...
A Case Report of Isoimmune Neonatal Thrombocytopenie Purpura.
Hye Ran Byun, Kyung Ha Ryu, Soon Hee Kim, Moon Ja Kim, Keun Lee
Clin Exp Pediatr. 1987;30(12):1452-1455.   Published online December 31, 1987
Isoimmune thrombocytopenic purpura is an uncommon cause of purpura in the newborn infant, caused by fetal-maternal platelet incompatibility. The maternal isoantibodies against fetal platelet antigens, which are lacked in mother’s platelets, cross placenta and cause destructions of baby’s platelet. A bady bom with IITP was diagnosed in the first day of life and treated successfully with platelet concentrate of mother’s blood.
PPD Conversion Rate and Complications According to the Different Time of BCG Vaccination.
Kyung Hyo Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(5):487-490.   Published online May 31, 1987
BCG vaccination shortly after birth has shown to protect against tuberculosis in some studies. PPD conversion rate and complications were compared between 174 neonates who received BCG vaccine within 1 week after birth and 330 infants who received BCG vaccine at the 1 month of age. The results were as follows: 1) The PPD conversion rate was 20.11% in the neonates who received vaccine within...
A Prospective Study ot Neonatal Acute Renal Failure: The Significance of Various Diagnostic Indices.
Kyung Hyo Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(4):378-384.   Published online April 30, 1987
Acute renal failure is defined as a sudden decrease in renal function resulting in progressive retention of nitrogenous waste products. Acute renal failure should be suspected in any infant who has a sustained decrease in urine output to less than 1 ml per kg per hour, a blood urea nitrogen level above 20 mg per dl, a serum creatinine level greater than 1.0...
The Study of Creatinine Clearance in Neonates.
Dong Sun Hong, Moon Ja Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(2):139-143.   Published online February 28, 1987
The creatinine clearance rate, an index of glomerular filtration rate, has been reported to develop according to gestational and postnatal age. The purpose of this study is to examine changes in creatinine clearance with gestational age and postnatal age in preterm and full term healthy neonates. The results were as follows: 1) The creatinine clearance rate increased according to gestational age. 2) The most in creament of creatinine...
Case Report
A Case of Iatrogenic Femoral Arteriovenous Fistula.
Kyung Hyo Kim, Moon Ja Kim, Kyung Hee Kim, Keun Lee
Clin Exp Pediatr. 1986;29(9):999-1001.   Published online September 30, 1986
Arteriovenous fistula is an abnormal vascular structure that establishes a communication between an artery and a vein without the interposition of the capillary bed. We experienced a case of iatrogenic femoral arteriovenous fistula in a six month-old girl. She was admitted with the chief complaint of different size of both lower leg which was first noted about l?/2 months PT A....
Original Article
Postnatal Changes of Serum Creatinine Levels in Neonates.
Jeong Wan Seo, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1986;29(9):948-953.   Published online September 30, 1986
The concentration of creatinine, one of the simple and commonly used indices of glomerular filtration rate in children and adults, has been reported to be appreciably raised and variable during the first month of life. This study examined the effect of gestational age(G.A.) on the postnatal changes of creatinine in preterm and full-term neonates. The results were as follows; 1) The mean...
Review
Psychosomatic Problems in Pediatrics.
Keun Lee
Clin Exp Pediatr. 1986;29(9):929-932.   Published online September 30, 1986
Original Article
The Effect of Intravenous Dextrose Water Given to Mother During Labor on Sodium Concentration of Maternal and Cord Serum.
Soo Kyung Chung, Dong Suk Suh, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1986;29(8):840-844.   Published online August 31, 1986
We studied the influence of intravenous electrolyte-free dextrose solution given to the mother during labor on the change of maternal and cord serum concentrations and the incidence of hyponatremia in 109 mothers and their newborns. 1) Na+ concentrations of maternal and cord serum in study group given intravenous electrolyte free dextrose solutions were 134.57土2.43 and 134.54±2.95, which was significantly lower,...
Clinical Status of Apnea in Prematurity.
Soon Hee Kim, Chang Soo Ra, Keun Lee
Clin Exp Pediatr. 1986;29(7):758-764.   Published online July 31, 1986
Apnea is defined as cessation of respiration for longer than 10 〜20sec with or without bradycardia or cyanosis. It is more frequent in premature than full-term infants. The medical records of 96 premature infants of gestational age below 36 weeks who were hospitalized at Nursery of Ewha University Hospital during the period from July, 1982 to July, 1984, were analyzed....
Estimation of Glomerular Filtration Rate from Plasma Creatinine and Height in Premature and Fullterm Neonates.
Yeong Jee Kim, Keun Lee
Clin Exp Pediatr. 1986;29(7):723-729.   Published online July 31, 1986
In clinical practice, creatinine clearance(Ccr) remains the most commonly used laboratory assessment of glomerular function despite methodological and technical problems of urine collection. Schwartz et al. in 1976，reported that an accurate estimate of glomerular filtration rate (GFR) could be obtained from the simple determinations of plasma creatinine (Per) and body length(L):GFR(ml/min/1.73cm2)=k• L(cm)/Pcr(mg/100ml), (k=constant). The purpose of this investigation is to compare...
Effects of Phototherapy on Peripheral Blood Findings in Full Term Newborns.
Moon Ja Kim, Keun Lee
Clin Exp Pediatr. 1986;29(7):710-714.   Published online July 31, 1986
The effects of phototherapy used in treatment of neonatal hyperbilirubinemia on peripheral blood findings were studied in full term newborns. There was no significant difference between daily mean hematocrits and WBC counts of phototherapy group and control group. The mean platelet count was not decreased during phototherapy in treated group, but significantly increased after phototherapy was stopped. 、
Case Report
2 Cases of Herpes Simplex Virus Infection in the neonates.
Kyung Hyo Kim, Jeong Wan Seo, Kyung Hee Kim, Keun Lee, Ki Sook Hong, Mi Ae Lee, Woon Sup Han, Ok Kyung Kim, Yung Oh Shin, Sung Bok Paik
Clin Exp Pediatr. 1986;29(1):101-107.   Published online January 31, 1986
Herpes simplex virus infection in the newborn is generally thought to be associated with a grave prognosis in terms of mortality and severe neurologic sequelae among survivors. Most neonatal herpes infection are due to type 2 herpes virus hominis, acquired either by ascending infection from the mother’s genital area to the intrauterine infant after premature rupture of membrame, or by...
Original Article
Clinical Observation on Very Low Birth Weight Infants.
Ran Ah Kim, Yeong Jee Kim, Kyung Hee KIm, Keun Lee
Clin Exp Pediatr. 1986;29(1):26-31.   Published online January 31, 1986
Charts of very low birth weight infants weighing less than 1,500 grams at birth were reviewed and the results analyzed. Infants were 107 in numbers, admitted to NICU, Ewha Womans University Hospital for the period of 4 years from July 1980 to June 1984 including outborns. Results were as follows: 1) Incidence of very low birth weight infant was 1....
Effects of Antenatal Indomethacin on Neonate.
Ja Ye Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1985;28(11):1066-1072.   Published online November 30, 1985
Prostaglandins play an important role in mediating uterine contractions and thus may also be involved in the triggering of premature labor and spontaneous abortion. Consequently inhibition of prostaglandin synthesis has been suggested as a potential means of inhibiting premature labor. There are many controlled studies which have described the use of indomethacin for inhibition of premature labor with success. But...
The Present Status of Infants Feeding in Korea.
Gyoung Hee Kim, Keun Lee, Choong Hee Kim, Keun Soo Lee, Sang Man Shin, Dong Gawn Han, Soo Jee Moon
Clin Exp Pediatr. 1985;28(10):960-966.   Published online October 31, 1985
A Survey on the present status of infants feeding in Korea was carried out during the period form July to September of 1984.
Nutrition of Low Birth Weight Infants and Infant Formula for Low Weight Infants.
Gyoung Hee Kim, Choong Hee Kim, Soo Jee Moon, Sang Man Shin, Dong Gawn Han, Keun Lee, Keun Soo Lee
Clin Exp Pediatr. 1985;28(10):953-959.   Published online October 31, 1985
Serum IgE Levels and Incidence of Atopic Disease according to Infant Diet.
Jeong Wan Seo, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1985;28(8):751-755.   Published online August 31, 1985
The role of breast feeding and dietary elimination of cow's milk as a mean of preventing atopic disease in infants remains controversial. From May 1983 to August 1984，the relationships between the type of feeding in early infancy and incidence of atopic disease were studied in 238 babies of less than 3 years of age and their serum IgE levels were compared....