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Original Article
Immunocytochemical Study for Lactalbumin in Alveolar Macrophage of Human Milk Aspirated Mouse
Byoung Kil Han, Young Hun Chung
Clin Exp Pediatr. 2003;46(6):536-540.   Published online June 15, 2003
Purpose : Aspiration of foreign material into the lungs can cause acute or chronic pulmonary diseases. It is difficult to detect small amounts of aspiration due to the lack of safe, sensitive and specific diagnostic tests. Recently, in animal or human studies, it has been reported that immunochemistry for lactalbumin can be used to detect the minimal aspiration. So, the...
Selective Gamma Globulin Treatment in Kawasaki Disease : The Comparison between Single 1g/kg and 2g/kg
Su Mi Ihn, Ren Zhe Ann, Hong Ryang Kil, Young Hun Chung
Clin Exp Pediatr. 2000;43(7):920-925.   Published online July 15, 2000
Purpose : Treatment of Kawasaki disease with intravenous gamma globulin(IVGG), together with aspirin, has been demonstrated to be safe and effective in preventing coronary artery lesion and systemic inflammation, but optimal IVGG dosage and administration method are still controversial. We compared the therapeutic efficacy and clinical response of single IVGG 1g/kg to that of IVGG 2g/kg for comparable risk group of Kawasaki disease. Methods :...
A Study on Clinical Application of Harada's Scoring Method to Kawasaki Disease - Suggesting the revision of the criteria for IVGG treatment of KD in Korea -
Byoung Kil Han, Hyong Shin Lee, Hong Ryang Kil, Heon-Seok Han, Jae Ho Lee, Young Hun Chung
Clin Exp Pediatr. 1997;40(4):539-548.   Published online April 15, 1997
Purpose : We performed a study on clinical benefits of Harada's scoring method, problems of present criteria and requirement of the revision of that criteria for intrvenos γ-globulin(IVGG) treatment of Kawasaki disease(KD) in Korea. Methods : The patients of 104 cases who visited to Department of Pediatrics of Chungnam National University Hospital and diagnosed as KD were objective group. We classified the...
A Study on the Serum Triglyceride Values in Children
Sang Won Cha, Young Hun Chung
Clin Exp Pediatr. 1994;37(11):1519-1525.   Published online November 15, 1994
The concentration of serum triglyceride values were studied at department of pediatrics, Chungnam National University Hospital. With the total 742 cases, among them 462 boys and 280 girls who were at the age of 2 months through 15 years old. Serum triglyceride values were measured to determine the distribution of values and evaluated on the basis of sex, age, height...
Clinical Study of Febrile convulsion and Factors Related to Recurrence
Jong Gyun Kim, Keon Su Rhee, Young Hun Chung
Clin Exp Pediatr. 1994;37(1):1-8.   Published online January 15, 1994
We have reserched the relationship of their clinical pictures and factors related to the risk of recurrence of 75 patients with simple or complex febrile convulsions, who were admitted to the Department of Pediatrics, Chungnam National University Hospital from January 1987 to July 1991. The 75 patient were followed up and consisted of the 55 patients with initial or non-recurrent...
Comparison and diagnostic Accuracy of Stable Microbubble Rating Test and Shake Test for the Early Detection of Respiratory Distress Syndrome
Hyeon Gon Kim, Sang Hyun Byun, Young Hun Chung
Clin Exp Pediatr. 1993;36(7):913-918.   Published online July 15, 1993
Respiratory distress syndrome of preterm infants remains a significant cause of morbidity and mortality. Early, just after birth, prediction and recognition of RDS is so important. The precision and reliability of the stable microbuble test (SMR) and shake test as a predictor of respiratory distress syndrome were studied. A 11-=neonate who was born at Chungnam National University Hospital between November 1991...
The Normal Serum Total Cholesterol Level in Children
Gyu Eun Whoang, Keun Su Rhee, Young Hun Chung
Clin Exp Pediatr. 1992;35(11):1559-1565.   Published online November 15, 1992
The measurement of serum total cholesterol was made in 1 month to 16 years of age group (total 1505, male 700, female 805) to know the normal value on each age and sex group, and incidence of hypercholesterolemia in children. The results were as follows: 1) Serum total cholesterol levels were 163.12¡¾38.01 mg/dl in male, 165.69¡¾38.24 mg/dl in female, and 164.40¡¾38.12 mg/dl...
A Significance of the Sinusitis in Asthma of Chileren
Kyong Og Ko, Young Hun Chung
Clin Exp Pediatr. 1992;35(11):1537-1545.   Published online November 15, 1992
It has long been recognized that sinusitis are commonly associated with asthma. Studies have observe a high coincidence of asthma and sinusitis. Despite observations of thease findings, a direct cause and effect relationship remains to be estabilished. So this study was undertaken to evaluate the relationship of bronchial asthma and sinusitis. 96 asthmatics and 127 non-asthmatic controls in children were taken...
Case Report
A Familial Case of Tricho-Rhino-Phalangeal Syndrome
Kyong Ok Ko, Sang Hyun Byun, Jong Jin Seo, Kun Su Rhee, Young Hun Chung, Yong Bae Sin
Clin Exp Pediatr. 1992;35(8):1135-1140.   Published online August 15, 1992
We experienced a familial case of Tricho-Rhino-Phalangeal syndrome in a 12-year-6-month-old girl, her younger sister and father. The diagnosis was made by family history history, characteristic morphologic clinical features of bulbous nose, sparse thin hair and deformity of hand and radiologic findings of cone shape epiphyses and Legg-perthes like change of right femoral capital epiphysis. A brief review of the...
Non-Hodgkin's Lymphoma of Bone with Multiple Punched-out Lesion on Simple Radiologic Examination
Gye Eun Whoang, Sang Hyun Byun, Jong Jin Seo, Keon Su Rhee, Young Hun Chung, Kwang Seon Seo, Cheol Woo Kim, Seong Hoae Kim
Clin Exp Pediatr. 1992;35(2):269-274.   Published online February 15, 1992
NHL is a malignant tumor that invade in abdominal cavity, mediastinum, cervical lymph node, rarely in peripheral lymph node, skin, and bone. Primary malignant lymphoma of bone with multiple punched-out lesion on simple radiologic examination was not reproted yet. We experienced a case of primary NHL of bone with multiple punched-out lesion on simple radiologic examination, in a 3-year 7-month old boy...
Original Article
Two cases of Gaucher disease in brother and sister.
Yong Ju Kim, Ki Young Cheong, Jong Jin Seo, Keon Su Rhee, Young Hun Chung, Seon Hoe Koo
Clin Exp Pediatr. 1991;34(8):1151-1156.   Published online August 31, 1991
We experienced two cases of Gaucher disease in brother and sister. The first case of 6 year old female showed hepatosplenomegaly with thrombocytopenia and characteristic Gaucher cells in bone marrow aspiration and biopsy. She is alive without complaints except abdominal distension. The second case of 3 year ~ 7 month old male showed hepatosplenomegaly with anemia and throm- bocytopenia. There were characteristic Gaucher cells...
A clinical study on the thyroid nodule in childhood.
Yong Ju Kim, Ki Young Cheong, Jong Jin Seo, Young Hun Chung
Clin Exp Pediatr. 1991;34(8):1116-1122.   Published online August 31, 1991
A clinical study was carried out in 27 children with thyroid nodule who visited the Dept, of pediatrics, Chungnam National University Hospital during the 4 year period from March 1986 to February 1990. The results are as follows; 1) The most frequent age group was between 10 to 15 year, and the mean age was 10.65 ±3.19 year. The male to female ratio was 1:4.4 2) All patients...
A clinical study of Graves' disease in children.
Kee Young Park, Ho Kyung Choi, Jong Jin Seo, Young Hun Chung
Clin Exp Pediatr. 1991;34(6):812-819.   Published online June 30, 1991
The authors analyzed the clinical manifestations, laboratory results, and relationship between the presence of antithyroid autoantibodies and response of short-term antithyroid medication in 20 children with Graves* disease who were diagosed at the Department of Pediatarics, Chungnam National Universtiy Hospital from March 1985 to February 1990. The results were as follows; 1) The ratio of male to female was 1:9. 2) The age distribution of patients ranged from...
A Case of Acute Rhenmatic Fever Associated with Acute Poststreptococcal Glomerulonepheitis.
Ho Kyung Choi, Dong Seok Choi, Jae Ho Lee, Young Hun Chung, Hyon Soon Lee
Clin Exp Pediatr. 1989;32(12):1744-1748.   Published online December 31, 1989
A case of acute glomerulonephritis in association with acute rheumatic fever was presented. The patient rheumatic arthritis and carditis with mitral insufficiency, who had been diagnosed as acute poststreptococcal glomeruoonephritis with non-oliguric renal failure with renal biopsy and laboratory findings. The patient was treated, and symptom and sign were improved.
A Trend of Serum C3 and C4 levels in Acute Poststreptococcal Glomerulonephirtis.
Dong Seok Choi, Young Hun Chung
Clin Exp Pediatr. 1989;32(7):965-971.   Published online July 31, 1989
Acute poststreptococcal glomerulonephritis is generally stated to be the most common cause of acute nephritis in childhood and secondary to an immunologic mechanism. In acute poststreptococcal glomerulonephritis, there have been several reports on the change of serum complement levels in the course of disease. This paper reports on observation of change of serum C3 & C4 levels and its clinical significance in 41 cases of...
A case of Pachyonychia Congenita.
Dong Seok Choi, Ho Kyung Choi, Keun Su Rhee, Young Hun Chung
Clin Exp Pediatr. 1989;32(6):872-876.   Published online June 30, 1989
A case of pachyonychia congenita occuring in a 15-month-old girl was reported with brief review of the literatures_ Brownish disc orated and excessively thickened nails with onychogryphosis, hyperkeratosis of soles and knees, follicular lesions on elbow, knees and trunk, and leukoplakia of the tongue and oral mucous membrane were noted.
A Case of Intestinal Tuberculosis with Huge Retroperitoneal Tuberculous Lymphadenitis Simulating Neoplasm.
Yong Suk Kim, Dong Seok Choi, Keon Su Rhee, Young Hun Chung
Clin Exp Pediatr. 1988;31(10):1385-1389.   Published online October 31, 1988
Since the advent of effective antituberculous chomtherapy in the 1940s, the frequency and severity of intestinal tuberculosis have markedly decreased. But the incidence of tuberculous disease is still high in Korea. We have recently experienced a cases of intestinal tuberculosis with huge retroperitoneal tuberculous lymphadenitis simulating neoplasm in 2 year 3 month old female. The cases was reported with the brief review of literatures.
A Study on Red Cell Distribution Width of Iron Deficiency Anemia in Childhood.
Hong Ryang Kil, Young Hun Chung
Clin Exp Pediatr. 1988;31(10):1321-1327.   Published online October 31, 1988
A hematologic study was undertaken on 60 cases of control group and 53 cases of iron deficiency anemia group who visited the outpatient department of Pediatrics, Chungnam National University Hospital from January, 1984 to July, 1987 The results were as follows: 1) In 60 cases of control group between 1 to 15 year, hemoglobin was 12.5±1.7 gm/dl, MCV 82.4± 3.8 fl, and RDW 13.1 ±1.1% and...
A Case of Mediastinal Gastroenteric Cyst.
Hong Ryang kil, Hye Suk Hong, Yang Won Lee, Jong Jin Seo, Young hun Chung, Seung Pyung Lim
Clin Exp Pediatr. 1988;31(7):924-929.   Published online July 31, 1988
Among heterogenous group of developmental anomalies known as enteric duplication, mediastinal gastroenteric cysts are rare and of outstanding diagnostic importance, because without definitive treatment they can be fatal. Unlike other mediastinal cysts they are almost never asymtomatic. The authors experienced a case of mediastinal gastroenteric cyst in 1 year 7 month-old female patient with chief complaint of abnormal mass density in chest X-ray. The...
A Case of Congenital Hepatic Fibrosis with Hypersplenism.
Hye Suk Hong, Yang Won Lee, Keon su Rhee, Young Hun Chung
Clin Exp Pediatr. 1987;30(12):1456-1460.   Published online December 31, 1987
Congenital hepatic fibrosis is a relatively rare disease of liver in children and young adults, manifesting a heredofamilial tendency, that is characterized by hepatosplenomegaly, protal hypertension and frequent renal involvement. A generalized portal and interlobular fibrosis of liver are characteristic finding on microscopy, with relative preservation of hepatocyte and liver function. Recently, we have experienced a case of congenital hepatic fibrosis in a...
A Case of Systemic Lupus Erythematosus Accompanied with Nephritis and Arteritis.
Oh Kyun Kwon, Hong Yang Khil, Jae Ho Lee, Young Hun Chung
Clin Exp Pediatr. 1987;30(11):1311-1317.   Published online November 30, 1987
The systemic lupus erythematosus (SLE) is a chronic inflammatory disease involving skin, kidney, serous membrane, nervous system and other organs. We experienced a case of SLE accompanied with nephritis and arteritis on the region of the left thigh, diagnosed by clinical, serologic, immunologic, radiologic and pathologic evaluations. A 15 years old female patient was admitted to pediatric ward due to sustained pain on left...
Plasma Renin Acivity in Children with Acute Glomerulonephritis and Nephrotic Syndrome.
Oh Kyun Kwon, Young Hun Chung
Clin Exp Pediatr. 1987;30(11):1213-1220.   Published online November 30, 1987
This is a study on plasma renin acitivity (PRA) which was obtanined from the patients with acute glomerulonephritis or nephrotic syndrome and normotensive control group admitted in Chungnam National University Hospital from Oct. 1985 to Aug. 1986 to confirm any differences of PRA between groups and to establish their influencing factors. The results were as follows; 1) PRA of noimal children in preschool age (3.49 ±0.98...
A Case of Caverneous Lymphangioma.
Yang Won Lee, Oh Kyun Kwon, Hye Suk Hong, YOung Hun Chung
Clin Exp Pediatr. 1987;30(2):229-233.   Published online February 28, 1987
caverneous lymphangioma in left neck and face, detected at birth and rapidly extended into adjacent tissues, such as infratemporal fossa, floor of mouth and anterior neck, which was confirmed surgically and pathologically and grave in prognosis.
A Study on Factor Influencing the Prognosis of Epidermic Encephalitis.
Sang Hyun Byun, Koe Jong Park, Jeong Soon Hwang, Young Hun Chung
Clin Exp Pediatr. 1983;26(10):978-985.   Published online October 31, 1983
The purpose Qf this study is to presume the severity of epidemic encephalitis. 36 cases were selected among 81 cases of epidemic encephalitis admitted to Chungnam National University Hospital during Jan. 1981 to Dec. 1982, and divided into clinically mild and severe group. Two groups were compared the differences of their demographic, clinical and laboratory findings. The parameters significantly more encountered in the severe...
Clinical Analysis on Accident of Children.
Kyung Sik Shin, Sang Hyun Byun, Kwang Joo Rhee, Suk Ja Kim, Young Hun Chung
Clin Exp Pediatr. 1982;25(8):829-838.   Published online August 31, 1982
There has been a significant decline of infectious disease in childhood due to an improvement of economy, living standard and medicine. But accidents in childhood is rather increased and encountered in major cause of death. The child is not so fully developed mentally and physically, that he is vulnerable to accident. Most accidents have been rocognized as being preventable with...
A Clinical Study on Predisposing Factors of Death on Neonatal Tetanus.
Keon Su Rhee, Young Hun Chung
Clin Exp Pediatr. 1982;25(7):699-707.   Published online July 31, 1982
Total 60 cases of the patients of neonatal tetanus were clinically evaluated who were admitted to the department of Pediatrics, Chungnam National University Hospital from Jan. 1976 to Dec. 1980 to identify the predisposing factors of death. The result were as follows; 1) The annual patients were encountered in 12 cases and the over all mortality was 42.9%. 2) Sex...
Clinical Review of Diabetes Insipidus in Children.
Chul Min Lee, Young Hun Chung
Clin Exp Pediatr. 1980;23(9):710-716.   Published online September 15, 1980
Clinical review of 5 pediatric diabetes insipidus, who have been admitted and treated at Dept. of Pediatric in Chungnam University Hospital from Aug. 1974 to May 1979, were summarized as follows: 1) The common complaints were polyuria and polydipsia, and anorexia, general weakness, poor visual acuity, vomiting, and headache were associated occasionally. 2) Male to female ratio was 3:2, the...
Observation on the Change of Body Weight and Calory Intake in Neonatal Period of Prematurity.
Sook Ja Kim, Young Hun Chung
Clin Exp Pediatr. 1980;23(3):210-219.   Published online March 15, 1980
Among 152 premature infants admitted to Nursery of Chung Nam National University Hospital between Jan, 1975 & December 1977. We selected 44 premature babies who were clinically normal, 30 to 37 weeks aged gestationally, 1000 to 2200 gm weighed at birth and admitted within 24hrs after birth & observed mainly on the change of their body weight & intake from...
Case Report
Hunter Syndrome.
Young You Kim, Chul Min Lee, Tae Woon Kim, Young Hun Chung
Clin Exp Pediatr. 1980;23(2):153-157.   Published online February 15, 1980
A 7-year and 5-month old boy with Hunter syndrome is presented. Progressive mental retardation with hearing loss, speech disturbance and growth retardation developed at 1 year of age. Physical findings included dull facial appearance, short stature, macrocephaly, short neck, non-tender scalp nodules, large tongue, thick lips with opened mouth, flat nasal bridge, hirsutism, hepatomegaly, umbilical hearnia, undescended testes, painful limitation...
Two Cases of Craniolacuna
Sang Man Kim, Kyoung Youl Oh, Hark Jin Chang, Tae Woon Kim, Young Hun Chung
Clin Exp Pediatr. 1975;18(12):953-957.   Published online December 31, 1975
Two cases of craniolacuna are reported. One is a four month-old male with a meningoencephalocele in the occiput. Skull X-ray films taken at age two days showed craniolacuna. It was not found on the films taken during admission at four months of age, and when hydrocephalus was evident. The other is a five month-old male with a meningocele in the posterior...