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- Case Report
- Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-α2b treatment
- Sun Ju Park, Dong Kyun Han, Hee Jo Baek, Sang Young Chung, Jong Hee Nam, Hoon Kook, Tai Ju Hwang
- Clin Exp Pediatr. 2010;53(11):975-978. Published online November 30, 2010
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A 7-year-old boy presented with hematochezia and abdominal pain. A 3.7-cm-sized mass was identified in the ascending colon by abdominal computed tomography and colonoscopy. The patient underwent surgical resection. Pathological examination revealed a low-grade perivascular epithelioid cell tumor (PEComa). PEComa in the colon is very rare. Only a few cases have been reported so far. An effective treatment method for...
- Review Article
- Role of colonoscopy in the diagnosis and treatment of pediatric lower gastrointestinal disorders
- Jae Hong Park
- Clin Exp Pediatr. 2010;53(9):824-829. Published online September 13, 2010
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The safety and effectiveness of colonoscopy in the investigation of lower gastrointestinal tract pathology in children has been established for more than 2 decades in Korea. Skill and experience have since advanced to the point that both diagnostic and therapeutic colonoscopy are now routinely performed by most pediatric gastroenterologists. Pediatric colonoscopy differs significantly from its adult parallels in nearly every...
- Case Report
- Perianastomotic ulceration presenting with long-term iron deficiency anemia and growth failure: A case report and review of the literature
- Kyung Ji Kang, Eun Ha Kim, Eun Young Jung, Woo-Hyun Park, Yu-Na Kang, Ae Suk Kim, Jin-Bok Hwang
- Clin Exp Pediatr. 2010;53(1):89-92. Published online January 15, 2010
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Perianastomotic ulceration (PAU) rarely occurs after small bowel resection in infancy. Since the understanding of its pathogenesis is incomplete, an effective method of treatment has not yet been discovered. We report the first case in Korea of a 10-year-old girl with chronic iron deficiency anemia (IDA) and growth failure who was diagnosed with PAU at colonoscopy. Seven years were required... -
- Original Article
- Molecular-epidemiologic study on outbreak of colonization by extended spectrum β-lactamase producing Klebsiella pneumoniae in neonatal intensive care unit
- Nu-Lee Jun, Mi-Na Kim, Jae-Sim Jeong, Yang-Soo Kim, Ellen Ai-Rhan Kim, Ki-Soo Kim, Soo-Young Pi
- Clin Exp Pediatr. 2006;49(2):150-156. Published online February 15, 2006
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Purpose : The aims of this study included assessment of molecular-epidemiologic features during an outbreak of colonization of extended spectrum β-lactamase producing Klebsiella pneumoniae(ESBL- KPN) and re-evaluation of their colonized status one year later. Methods : Rectal swab cultures for ESBL-KPN from all hospitalized infants and newly admitted infants were obtained during the outbreak of colonization from July to December,... -
- Prevalence and Risk Factors of Vancomycin-Resistant Enterococci (VRE) Colonization in Neonates
- Hwa Yun Lee, Gi Hwan Kim, Jin Su Choi, Sun Hee Kim, Young Youn Choi, Tai Ju Hwang
- Clin Exp Pediatr. 2005;48(9):946-952. Published online September 15, 2005
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Purpose : Vancomycin-resistant enterococci(VRE) are now nosocomial pathogens in Korea. But little is known about the prevalence of stool colonization with VRE in neonates in Korea. So we studied the prevalence and risk factors of VRE colonization in the Neonatal Intensive Care Unit(NICU). Methods : From January 2000 to December 2004, the medical records of 294 neonates(127 cases of VRE group... -
- Ex vivo Expansion and Clonal Maintenance of CD34＋ Selected Cells from Cord Blood and Peripheral Blood
- Soon Ki Kim, Hye Yoon Ghil, Sun U. Song, Jong Weon Choi, Sang Kyu Park
- Clin Exp Pediatr. 2005;48(8):894-900. Published online August 15, 2005
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Purpose : Because of the unavailability of marrow transplantation, umbilical cord blood (CB) is increasingly being used. We evaluated the potential of ex vivo expansion and clonality in CD34＋ cells separated from cord blood source and mobilized peripheral blood (PB) in a serum-free media. Methods : The CD34＋ cells, selected from CB and mobilized PB, were expanded with hematopoietic growth... -
- Colonic Polyps; Experience of 34 Cases in Two Hospitals
- Seoung Joon Kim, Sun Mi Kim, You Jeong Kim, Dae Chul Jeong, Won Bae Lee, Seung Yun Chung, Jin Han Kang
- Clin Exp Pediatr. 2004;47(7):756-761. Published online July 15, 2004
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Purpose : Colonic polyps are among the most common causes of rectal bleeding in children. We studied the clinical spectrum, histology, malignant potential and treatment of colonic polyps in our cases. Methods : We reviewed hospital charts of all patients with colonic polyps, seen over a 15-year period from January 1988 to November 2002. Colonoscopy and/or barium enema were done for... -
- A Clinical Study of Acute Colonic Diverticulitis in Children
- Jae Hoon Sim, Keum Ho Song, Yun Jung Sim, Do Jun Cho, Dug Ha Kim, Ki Sik Min, Ki Yang Yoo, Hae Ran Lee, Kwan Seop Lee
- Clin Exp Pediatr. 2003;46(11):1095-1100. Published online November 15, 2003
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Purpose : Children with acute colonic diverticulitis(ACD), can be misdiagnosed with acute appendicitis. Methods : We reviewed 15 cases of ACD during five years, from January 1998 to June 2002 retrospectively. Results : Most patients(80%) with ACD in children presented with right lower quadrant pain. The primary diagnosis on admission was mostly acute appendicitis(87%), and all ACD in children occurred in... -
- Plasma G-CSF and GM-CSF Concentration and Amount of Their Receptors on the Granulocyte in Kawasaki Disease
- Young-Kyoung Yoo, Gibum Lee, Hyun-Hee Kim, Soo-Young Kim, You-Jeong Kim, Wonbae Lee
- Clin Exp Pediatr. 2003;46(4):376-381. Published online April 15, 2003
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Purpose : This study aimed to demonstrate the possible pathogenesis of granulopoiesis in patients of Kawasaki disease(KD) using quantitative analysis of G-CSF, GM-CSF and their CSFr. Methods : The plasma levels of G-CSF, GM-CSF, G-CSFr and GM-CSFr were studied in 14 patients in the acute phase of KD; 13 children with normal peripheral white blood cell counts were used as the... -
- Plasma G-CSF and GM-CSF Concentrations and Expression of their Receptors on the Granulocyte in Children with Leukocytosis
- Won Seok Choi, Kyung Hwan Ryu, You Jeong Kim, So Young Kim, Hyun Hee Kim, Wonbae Lee
- Clin Exp Pediatr. 2003;46(3):271-276. Published online March 15, 2003
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Purpose : Granulocyte-colony stimulating factor(G-CSF) and granulocyte macrophage-colony stimulating factor(GM-CSF) are principal cytokines in granulopoiesis and their physiologic effects are mediated through binding to specific cell surface receptors. Although it is known that the level of serum G-CSF and GM-CSF, and presentation of the receptors are increased in infectious diseases, there have been no studies to find the correlation between... -
- Case Report
- A Case of Scoliosis Due to a Foreign Body(Pencil) in the Colon
- Jeong Sik Seo, Sun Mi Chung, Eun Jin Choi, Jin Kyung Kim, Un Seok Nho, Hai Lee Chung, Dae Hyun Joo, Woo Taek Kim
- Clin Exp Pediatr. 2002;45(11):1417-1421. Published online November 15, 2002
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Scoliosis describes a lateral curvature of the spine and is often associated with cosmetic and functional impairments due to severe deformity of the spine. The incidence of adolescent scoliosis is 2-4% of children between 10 and 16 years of age. Eighty five percent of them are idiopathic, in which the most common type of scoliosis is right side-bending. In addition,... -
- Original Article
- Therapeutic Effect of Different Doses of Recombinant Human Granulocyte Colony-Stimulating Factor(rhG-CSF) on Neonatal Sepsis Complicated by Neutropenia
- Moon Young Choi, Yeon Sook Jung, Dong Woo Son, Hyo Seop Ahn
- Clin Exp Pediatr. 2002;45(4):439-448. Published online April 15, 2002
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Purpose : The aim of this study is to determine and compare the effects of adjunctive therapy with different doses of recombinant human granulocyte-colony stimulating factor(rhG-CSF) on reversing sepsis-associated neonatal neutropenia, and their survival rate in a group I/II-type trial. Methods : RhG-CSF was injected subcutaneously to 10 septic-neutropenic neonates with doses of 10 μg/kg from Oct. 1995 to Sep. 1996,... -
- Serogroup and Antimicrobial Resistance of Streptococcus pneumoniae Isolated from Oropharynx in Children Attending Day Care Center
- Kyung Hyo Kim, Jong Eun Lee, Il Tae Whang, Kyung Ha Ryu, Young Mi Hong, Gyoung Hee Kim, Keun Lee, Eun-Suk Kang, Ki-Sook Hong
- Clin Exp Pediatr. 2002;45(3):346-353. Published online March 15, 2002
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Purpose : Penicillin- and multidrug-resistant S. pneumoniae poses a serious threat to clinicians because the rate of resistance of S. pneumoniae to penicillin in Korea has surged up to the world's highest level. This study was performed to assess the carriage rate, serogroups and antimicrobial susceptibility of S. pneumoniae isolated from oropharynx in children. Methods : From March to July 1998,... -
- Colonic Transit Time in Chronic Constipated Patients
- Je Eun Choi, Im Jeong Choi, Jung A Lee, Sung Mi Kim, Jin Hwa Jeong, Jeong Ho Lee
- Clin Exp Pediatr. 2001;44(7):752-757. Published online July 15, 2001
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Purpose : In most instances, constipation is considered as idiopathic or functional. The total colonic transit time, traced by radio-opaque markers, makes possible the identification of the colon segment that has the motility alteration that causes constipation. We measured the total and segmental colonic transit time in children with chronic idiopathic constipation and compared the results with those without constipation... -
- Effect of Granulocyte-macrophage Colony-stimulating Factor in Neonatal Infection
- Il-Young Jo, Sang-Hyun Byun
- Clin Exp Pediatr. 2000;43(12):1552-1557. Published online December 15, 2000
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Purpose : Neutrophils are central to the defences against bacterial infection, and in neonates the number of neutrophils are decreased due to inhibited production and phagocytic function. This induces high mortality rates in infants suffering from neonatal sepsis. Exogenous GM-CSF can increase the number of neutrophils and improve the phagocytic function. To establish the most cost effective dose of exogenous... -
- Case Report
- A Case of Megacystis Microcolon Intestinal Hypoperistalsis Syndrome
- Jae Woo Lim, Jong Su Shin, Kyuchul Choeh, Chang Su Na, Tae Il Han
- Clin Exp Pediatr. 2000;43(2):278-282. Published online February 15, 2000
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Megacystis Microcolon Intestinal Hypoperistalsis(MMIH) Syndrome is a rare cause of functional neonatal bowel obstruction, characterized by hypoperistalsis, narrow distal ileum and colon, and bladder distension. We report a case of MMIH syndrome and review the literature. The patient was born after 34 weeks of gestation with marked abdominal distension. Her birth weight was 2,830g with 276ml of urine drained by... -
- Original Article
- A Clinical and Histological Study of Allergic Colitis in Infant
- Jae Bok Kim, Kyung Mo Kim, Ki Soo Kim, Soo Young Pi, Yang Soon Park
- Clin Exp Pediatr. 1998;41(4):521-528. Published online April 15, 1998
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Purpose : This study was done to evaluate the clinical and pathologic aspects of allergic colitis. Methods : This study evaluated 19 infants who presented with fresh blood mixed stools. Limited colonoscopy and biopsy were performed. Among the 19 infants, 13 infants were diagnosed as allergic colitis by histological findings. We analyzed the clinical and histological characteristics of 13 infants. Results : Male and female... -
- Colonic Transit Time in Children with Recurrent Abdominal Pain
- Je Woo Kim, Ki Sup Chung
- Clin Exp Pediatr. 1997;40(11):1544-1551. Published online November 15, 1997
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Purpose : Recurrent abdominal pain is defined as the presence of at least three discrete episodes of pain occurring over a period of 3 or more months. The reported prevalence is high up to 15% of school aged children. Mostly the pain results from functional dysmotility of the intestine but not much studies has been done. Thus we studied segmental colonic transit time(CTT)... -
- Constipation in Children-Colonic Transit Time and the Barr-Score
- Nam-Seon Beck, I Sok Kang, Dong Kyu Jin, Munhyang Lee, Sang Il Lee, Heung Jae Lee, Bokyung Kim, Tae Sung Park
- Clin Exp Pediatr. 1997;40(10):1427-1434. Published online October 15, 1997
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Purpose : We have assessed the clinical usefulness of solid maker transit technique and Barr-score in 31 patients with idiopathic constipation (male:female; 17:14, mean age; 6.7 years, range 1.4-12 years). Methods : All patients underwent full history taking and physical examination including rectal examination. On first visit to gastroenterology clinic a plain abdominal film was taken for Barr-score which evaluated by two observers without the... -
- Case Report
- Two Cases of Congenital Atrichia Associated with the Gastrointestinal Anomaly in Siblings
- Jin Kyung Jung, Sang Ho Baik, Sa Young Kim, Eui Tak Oh, Hong Ja Kang, Kil Seo Kim
- Clin Exp Pediatr. 1996;39(9):1315-1320. Published online September 15, 1996
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Congenital atrichia is an anomaly characterized by congenital absence of hair in varying degrees as well as the hypopigmentation & poor development of the abnormal residual hair on the scalp, eyebrows, eyelashes & body. Two cases of congenital atrichia in siblings were reviewed. The first case was associated with congenital megacolon and skin biopsy of scalp (esp. parietal region) was non-specific. The... -
- Angiodysplasia Involving the Sigmoid Colon in Children
- Jae Young Kim, Kyung Won Hwang, Young Ho Ahn, Jin Bok Hwang, Chang Ho Han, Hae Lee Chung, Young Dae Kwon, Yong Jin Kim
- Clin Exp Pediatr. 1995;38(7):993-999. Published online July 15, 1995
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Angiodysplasia(AD) of the gastrointestinal(GI) tract in children is a very rare cause of bleeding and thought to be a distinct clinicopathologic entity distingishing from the classic adult-type AD by its different clinical settings and diverse histology. We report two cases of AD involving the sigmoid colon in children. The cases, 6-year-old girl and 11-year-old boy, were preoperatively suspected by colonoscopy and... -
- Two Cases of Total Colon Aganglionosis Involving Small Bowel in Triplet
- Won A Park, Hyun Joo Kim, Kyung Dug Moon, Hea Kyoung Lee, Young Hee Yu, Hyun Suk Lee
- Clin Exp Pediatr. 1994;37(10):1463-1469. Published online October 15, 1994
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Total or mostly total intestinal aganglionosis is rare and invariably fatal. All patients with aganglionosis involving more than half of the small bowel have died with persistent intestinal obstruction and secondary maluntrition and infection. Recently, we experienced two cases of total colon aganglionosis extending to the middle of the jejunum in triplet. We report the cases with brief review of literatures. -
- A Case of Syndrome Associated with Colonic Atresia
- Si Whan Koh, Joon Soo Park, Kyung Hwan Oh, Dong Hwan Lee, Sang Jhoo Lee, Chul Moon
- Clin Exp Pediatr. 1993;36(7):1030-1033. Published online July 15, 1993
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The association of colonic atresia in patients with Down syndrome is a rare anomaly. The incidence of congenital atresia of the gastrointestinal tract has been estimated to be about one in 1500 births. Colonic atresia is rarer still, and is throut to comprise about 5% to 10% of this group. This intestinal atresia occurs in about 30% to 50% of... -
- Original Article
- Urinary Tract Infection and Neonatal Circumcision
- Seung Joo Lee
- Clin Exp Pediatr. 1992;35(8):1035-1043. Published online August 15, 1992
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An association between urinary tract infection in male infants and uncircumcised status has been suggested recently. Male predominance of UTI in most reports in Korea may be related to this uncircumcised status. The present study was prospectively performed between Mar. 1989 and May. 1991 to investigate this relationship and the effect of neonatal circumcision on the intraurethral bacterial flora. 1) The... -
- The clinical review of congenital magacolon.
- Myung Goo Min, Ki Sup Chung
- Clin Exp Pediatr. 1991;34(10):1373-1380. Published online October 31, 1991
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This clinical study presents an anlaysis of 102 patients who underwent definitive surgery for Hirschsprung’s disease from January 1979 to April 1990 at Department of Pediatrics, Yonsei Univer- sity College of Medicine. The results were summarized briefly as follows: 1) The sex ratio was 2.6:1, of male preponderence. 2) The first symptom appeared within 1 month after birth in majority of cases, in 82 cases (80.4%) and diagnosis... -
- Accuracy of anorectal manometry in the diagnosis of congenital megacolon.
- Jong Yul Jeon, Byeong Gie Yeo, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn, Young Woon Chang
- Clin Exp Pediatr. 1991;34(5):614-620. Published online May 31, 1991
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Thirty-seven patients with clinical impression of congenital megacolon were studied with anorectal manometry for the evaluation of its diagnostic accuracy. Including 12 neonates, their age ranged form 3 days to 8 years and barium enema was performed to all of them except one. The results of rectosphincteric reflex (RSR) of anorectal manometry was compared with the final diagnosis, which was obtained by clinical course,... -
- Colonization Factor Antigens of Heat-stable Enterotoxin-Producing (STf) E. Coli in Korean Children.
- Kon Hee Lee, Kyung Hee Kim, Yang Ja Cho
- Clin Exp Pediatr. 1989;32(9):1210-1215. Published online September 30, 1989
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Enterotoxigenic Escherichia coli (ETEC) cause an acute cholera-like diarrhea in both human and animals. The disease process involves colonization of the mucosal surfaces of the small intestine followed by elaboration of ST and/or heat-labile enterotoxin (LT). Intestinal colonization by ETEC is mediated by specific surface-associated fimbrial or fibrillar antigens including colonization factor antigens (CFA) I and II. Isolates of E. coli from 114 children with... -
- Case Report
- A Case of Primary Mucinous Adenocarcinoma of the Colon in Children.
- Chi Ho Yoon, Kyung Ae Lee, Jung Mo Ryu, Soon Hee Choi, Kyu Geun Cho
- Clin Exp Pediatr. 1985;28(11):1136-1140. Published online November 30, 1985
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Malignant diseases of tte colon are rare during childhood. The etiology of disesaes has not not been clearly defined, but diet, exposure to farm chemical, carcinogens, bile acid, clostria, and genetic factors are associated with large bowel cancer. 50% of the adenocarcinoma in children are of the mucin producing variety. The prognosis of childhood cancer of the colon is very poor,... -
- A Case of Primary Mucinous Adinocarcinoma (Colloid) of Colon in Children.
- Kyoung Nam Kim, Won Ik Lee, Sung Chul Son, Poong Man Lee
- Clin Exp Pediatr. 1983;26(4):397-401. Published online April 30, 1983
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Carcinoma of the colon in childhood has remained extremely rare, and especially, primary carcinoma of colon was often escapes early diagnosis because of a lack of awarenss of its occurrence in pediatric age group. Recently we experienced a case of mucinous adenocarcinoma (Colloid carcinoma) of descending colon without predisposing conditions which may increased the risk of development of colorectal cancer in 13... -
- One Case of Neonatal Peritonitis Complicated by Anal Stenosis.
- Byung Giu Kim, Su Yung Kim, Sook Hyeon Yoon, Jong Dae Jo
- Clin Exp Pediatr. 1981;24(7):671-676. Published online July 15, 1981
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The anorectal anomaly is not rarely seen in the neonatal period. But, If it is not accompanied with a fairly large fistula, it presents an urgent problem, so should be managed with perianal anoplasty or colostomy. Neonatal peritonitis is very grave and is caused by various conditions listed in Table 1. In Korea, no case of neonatal peritonitis caused by... -
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