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Original Article
Neonatal risk factors associated with autism spectrum disorders: An umbrella review
Amir Mohammad Salehi, Erfan Ayubi, Salman Khazaei, Ensiyeh Jenabi, Saeid Bashirian, Zohreh Salimi
Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by severe social communication deficits and stereotypical repetitive behaviors.
Purpose: This umbrella review assessed neonatal risk factors associated with ASD using meta-analyses and systematic reviews. Methods: We conducted a systematic search of interna-tional databases including PubMed, Scopus, and Web of Science for studies published through April 2022 utilizing pertinent keywords. A random-effects...
Review Article
Other
Use of virtual reality in children in a broad range of medical settings: a systematic narrative review of recent meta-analyses
Emily Antonovics, Grammatina Boitsios, Thomas Saliba
Clin Exp Pediatr. 2024;67(6):274-282.   Published online May 21, 2024
· Virtual reality (VR) is becoming increasingly common for entertainment and in medical settings.
· VR is useful for treating children with cerebral palsy.
· VR can help with attention deficit/hyperactivity disorder symptoms.
· VR can decrease pain perception in children undergoing burn wound care.
· VR can reduce preoperative anxiety.
· VR can reduce fear and pain during needle-involving procedures.
Original Article
Developmental and Behavioral Medicine
Neonatal risk factors associated with attention-deficit/hyperactivity disorder: an umbrella review
Ensiyeh Jenabi, Erfan Ayubi, Sajjad Farashi, Saeid Bashirian, Fereshteh Mehri
Clin Exp Pediatr. 2023;66(10):441-446.   Published online July 14, 2023
Question: The risk factors for attention deficit hyperactivity disorder (ADHD), such as breastfeeding, congenital heart disease, and low birth weight, in neonates are not well understood.
Finding: This umbrella review obtained significant effect sizes for ADHD for congenital heart disease (odds ratio [OR], 3.04), low birth weight (OR, 2.25), never breastfed (OR, 1.55), and Apgar score (OR, 1.30).
Meaning: Congenital heart disease, low birth weight, lack of breastfeeding, and Apgar scores were significant factors for ADHD.
General Pediatrics
Virtual reality for pain reduction during intravenous injection in pediatrics: a systematic review and meta-analysis of controlled clinical trials
Ensiyeh Jenabi, Saeid Bashirian, Amir Mohammad Salehi, Masoud Rafiee, Mozhdeh Bashirian
Clin Exp Pediatr. 2023;66(12):533-537.   Published online June 14, 2023
Question: This is the first meta-analysis to examine published evidence of the effectiveness of virtual reality at reducing pain during pediatric intravenous injections.
Finding: Our results suggest that virtual reality effectively reduces pain associated with intravenous injections in pediatric patients.
Meaning: These findings suggest the importance of virtual reality in decreasing the pain of intravenous injections among children.
Review Article
Nephrology (Genitourinary)
Treatment of refractory IgA vasculitis with dapsone: a systematic review
Keum Hwa Lee, Sung Hwi Hong, Jinhae Jun, Youngheun Jo, Woogyeong Jo, Dayeon Choi, Jeongho Joo, Guhyun Jung, Sunghee Ahn, Andreas Kronbichler, Michael Eisenhut, Jae Il Shin
Clin Exp Pediatr. 2020;63(5):158-163.   Published online September 24, 2019
IgA vasculitis, formerly known as Henoch-Schönlein purpura, is a systemic IgA-mediated vasculitis of the small vessels commonly seen in children. The natural history of IgA vasculitis is generally self-limiting; however, one-third of patients experience symptom recurrence and a refractory course. This systematic review examined the use of dapsone in refractory IgA vasculitis cases. A literature search of PubMed databases retrieved...
Original Article
Intercontinental comparison of caustic ingestion in children
Mandana Rafeey, Morteza Ghojazadeh, Amir Mehdizadeh, Hakimeh Hazrati, Leila Vahedi
Clin Exp Pediatr. 2015;58(12):491-500.   Published online December 22, 2015
Purpose

To investigate the caustic ingestion in children among different continents according to demographic characteristics (core purpose), main symptoms, common caustic agents, signs and symptoms, management, treatment and complications.

Methods

This systematic review was performed by searching the databases Science Direct, ProQuest, Google Scholar, and PubMed, electronically and manually. We included studies that were published from 1980 to 2013, at University of Medical...

Dietary patterns and metabolic syndrome risk factors among adolescents
Hyojee Joung, Soyoung Hong, Yoonju Song, Byung Chul Ahn, Mi Jung Park
Clin Exp Pediatr. 2012;55(4):128-135.   Published online April 30, 2012
Purpose

Unbalanced diets and decreased physical activity have contributed to increased prevalence of obesity and metabolic syndrome in adolescents. We have performed a systematic review and data analysis to examine the association between dietary pattern and metabolic syndrome risk factors in adolescents.

Methods

We searched the PubMed and BioMedLib databases for appropriate articles published during the past 10 years and selected 6 articles....

Erratum
Ethical considerations for clinical trials performed in children
Myungho Oh
Clin Exp Pediatr. 2009;52(1):1-5.   Published online January 15, 2009
Children are not small adults and there is a need to carry out specific trials that cannot be performed in adults. In general, children (minors) are unable to consent but their assent should be obtained using age appropriate information. Institutional Review Board (IRB) need paediatric expertise to balance the benefits and risks of research in children. The lack of consent...
Review Article
Attention deficit hyperactivity disorder
So-Hee Eun, Baik-Lin Eun
Clin Exp Pediatr. 2008;51(9):935-943.   Published online September 15, 2008
Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral developmental disorder characterized by a persistent pattern of inattention and/or hyperactivity, as well as forgetfulness, poor impulse control or impulsivity, and distractibility. The recommended evaluation includes documenting the type and severity of ADHD symptoms, verifying the presence of normal vision and hearing, screening for comorbid psychological conditions, reviewing the child`s developmental history...
Original Article
Changes of Clinical Patterns of the Acute Rheumatic Fever in Korea(Compared report of 1973-1985 with that of 1986-1992)
Hye Sun Yoon, Min Young Park, Wan Young Shin, Byong Soo Sco, Sung Ho Cho
Clin Exp Pediatr. 1995;38(4):470-481.   Published online April 15, 1995
Purpose : The annual incidence of acute rheumatic fever in Korea was not changing during 1980 to 1989 from Nationwide survey in 1991 in spite of talking about scanty outbreak among doctors in recent year.The proportion of patients with acute rheumatic fever among the entire pediatirc inpatients each year was approximately 0.3% and did not change significantly throughout the...
Clinical Observation of Tricuspid Atresia.
Myung Hyun Lee, Yong Soo Yoon, Chang Yee Hong
Clin Exp Pediatr. 1983;26(8):751-759.   Published online August 31, 1983
Twenty one cases of triciispid atresia which were diagnosed at the department of Pediatrics, Seoul National University Hospital during past twelve years and eleven months were reviewed and analysed. The results were as follows. 1) There were 8 males and 13 females. According to anatomical classification, 15 cases were in type 1, 4 cases in type 표 and 2 cases in type...
A Clinical Review of Miliary Tuberculosis in Children.
You Nam Kim, Seung Joon Park, Heung Kyu Kim, Ki Bok Kim
Clin Exp Pediatr. 1982;25(4):363-372.   Published online April 30, 1982
A Clinical study was made of 88 pediatric patients with miliary tuberculosis, who were admitted to the Pediatric Department of Kwangju Christian Hospital during the period of January, 1971 through December, 1980. 1) The incidence of miliary tuberculosis in children was 0.6%(88 cases) of the total pediatric admission cases(13969), and 12.5% (88 cases) of the total pediatric tuberculous patiens(705). 2)...
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