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"Most downloaded" Articles are from the articles published in 2022 during the last six months.
- Review Article
- Infection
- Etiological and pathophysiological enigmas of severe coronavirus disease 2019, multisystem inflammatory syndrome in children, and Kawasaki disease (8 times)
- Jung-Woo Rhim, Jin-Han Kang, Kyung-Yil Lee
- Clin Exp Pediatr. 2022;65(4):153-166. Published online November 23, 2021
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· Severe cases of coronavirus disease, Kawasaki disease (KD), and multisystem inflammatory syndrome in children (MIS-C) share similar findings: a protracted clinical course, multiorgan involvement, and similar activated biomarkers.
· Here we propose etiological agents in KD and MIS-C as species in the microbiota and introduce a common pathogenesis through the protein-homeostasis-system hypothesis.
· Early proper dose of corticosteroids and/or intravenous immunoglobulin may help to reduce morbidity and mortality in these diseases.
- General Pediatrics
- A new perspective on cholesterol in pediatric health: association of vitamin D metabolism, respiratory diseases, and mental health problems (8 times)
- Jeana Hong
- Clin Exp Pediatr. 2022;65(2):65-72. Published online December 9, 2021
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∙ Pediatric dyslipidemia is associated with several health problems besides cardiovascular diseases.
∙ There is a direct association between pediatric dyslipidemia and low serum vitamin D levels, asthma, and mental health problems regardless of body mass index.
∙ More large-scale nationally representative studies are needed to establish the appropriate cutoff points for the definition of dyslipidemia that is a prerequisite for further epidemiological studies in the Korean pediatric population.
- Correspondence and Reply
- Neurobehavior
- Association between polycystic ovary syndrome and risk of attention-deficit/hyperactivity disorder in offspring: a meta-analysis (8 times)
- Hadith Rastad, Mahnaz Seifi Alan
- Clin Exp Pediatr. 2022;65(3):152-152. Published online February 17, 2022
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- Editorial
- Cardiology
- Early echocardiographic screening for subclinical myocardial dysfunction in children and adolescents with dyslipidemia: why and when? (8 times)
- Hyun Gyung Lee, Hwa Jin Cho
- Clin Exp Pediatr. 2022;65(8):398-400. Published online March 7, 2022
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Dyslipidemia contributes to early atherosclerosis, premature cardiovascular disease, and subclinical ventricular dysfunction in children. This paper highlights the need for echocardiographic evaluation for impaired diastolic function of both ventricles and narrowing of the aortic valve and sinus of Valsalva. Therefore, early echocardiographic screening of children with primary hyperlipidemia should be considered.
- Letter to the Editor
- Infection
- Changes in epidemiology of parainfluenza virus and respiratory syncytial virus infection during coronavirus disease 2019 pandemic in Korea (8 times)
- Kyung-Ran Kim, Hwanhee Park, Doo Ri Kim, Yae-Jean Kim
- Clin Exp Pediatr. 2022;65(6):320-321. Published online March 10, 2022
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Question: How the epidemiology of other childhood respiratory viruses has changed during coronavirus disease 2019 (COVID-19) in Korea?
Finding: Parainfluenza virus (PIV) typically circulated in the spring, and respiratory syncytial virus (RSV) epidemic started in autumn in Korea before COVID-19 pandemic. PIV and RSV seasons disappeared in 2020 and came back in 2021 with atypical seasonality. PIV season was changed from spring to autumn, and the beginning of RSV season was slightly delayed from autumn to early winter in 2021.
Meaning: Circulation of PIV and RSV was changed to unusual seasons and patterns during COVID-19 pandemic period.
- Original Article
- Neonatology (Perinatology)
- Mediation effect of cord blood cortisol levels between maternal prepregnancy body mass index and birth weight: a hospital-based cross-sectional study (8 times)
- Nisanth Selvam, Jayashree K, Prasanna Mithra
- Clin Exp Pediatr. 2022;65(10):500-506. Published online July 29, 2022
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Question: What is the association between cord blood cortisol and maternal weight, birth weight, and cord blood lipid profile?
Finding: Cord blood cortisol levels did not influence the relationship between maternal weight changes or birth weight. Maternal weight changes, birth weight, and cortisol levels altered the cord blood lipid profile.
Meaning: Our findings may aid United Nations Sustainable Development Goal 3 (Good Health and Well-Being) achievement by 2030.
- Letter to the Editor
- Infection
- Chest x-ray findings in children with COVID-19: lesson learned from referral hospitals in Medan, North Sumatera, Indonesia (8 times)
- Andrew Limavady, Eka Airlangga, Ririe Fachrina Malisie, Ayodhia Pitaloka Pasaribu
- Clin Exp Pediatr. 2023;66(7):317-319. Published online May 16, 2023
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- Editorial
- Emergency Medicine
- Current diagnosis and image-guided reduction for intussusception in children: teamwork approach (8 times)
- Ji-Hyun Seo
- Clin Exp Pediatr. 2023;66(2):66-67. Published online September 1, 2022
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· The successful and safe enema reduction of intussusception depends primarily on the experience and preference of the radiologists and the availability of resources.
· The establishment of a standardized manual or protocol for reduction and pre-reduction treatment of intussusception, along with the collaboration of pediatricians, radiologists, and surgeons, is expected to improve the treatment success rate.
- Review Article
- Allergy
- Management of patients with allergic diseases in the era of COVID-19 (8 times)
- Eun Lee
- Clin Exp Pediatr. 2022;65(11):529-535. Published online September 23, 2022
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In the early days of the coronavirus disease 2019 (COVID-19) pandemic, allergic diseases, especially asthma, were considered to be risk factors for severe COVID-19 infection, hospitalization, and death. These concerns stemmed from the idea that individuals with allergic diseases are generally more susceptible to respiratory virus infections, which are major causes of exacerbation of allergic diseases. However, epidemiologic data with...
- Editorial
- Neonatology (Perinatology)
- Does cord blood cortisol have a mediating effect on maternal prepregnancy body mass index and birth weight? (8 times)
- Gyu Hong Shim
- Clin Exp Pediatr. 2023;66(1):24-25. Published online November 30, 2022
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· A high prepregnancy body mass index (pre-BMI) is associated with large for gestational age (LGA) and macrosomia, whereas a low pre-BMI is associated with small for gestational age (SGA) and low birth weight (LBW).
· The identification of the role of the hypothalamus-pituitary-adrenal axis in the effect of pre-BMI and maternal gestational weight gain on birth weight could reduce the frequency of LGA, macrosomia, SGA, or LBW through maternal diet optimization.
- Gastroenterology
- Recent advances in epigenetic mechanisms, diagnosis, and treatment of pediatric gastrointestinal allergic disorders (8 times)
- Eell Ryoo
- Clin Exp Pediatr. 2023;66(6):250-251. Published online May 19, 2023
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· Epigenetic mechanisms are involved in rapidly increasing food allergy.
· There is still no definitive way to diagnose food allergy.
· Early introduction of peanuts, eggs, and cow’s milk reduces food allergy incidence.
· Administration of probiotics such as Lactobacillus rhamnosus GG, Bifidobacterium bifidum can partially reduce the occurrence of allergic symptoms.
- Clinical note
- General Pediatrics
- Diabetic ketoacidosis in children induced by coronavirus disease 2019 (COVID-19) diabetic ketoacidosis post-COVID-19 in children (7 times)
- Neha Thakur, Narendra Rai
- Clin Exp Pediatr. 2022;65(4):209-210. Published online November 30, 2021
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- Original Article
- Cardiology
- Early myocardial functional abnormalities in primary dyslipidemia: clinical and echocardiographic observations in young children from a highly consanguineous population (7 times)
- Nehal M. El-koofy, Aya M. Fattouh, Areef Ramadan, Mohamed A. Elmonem, Dina H. Hamed
- Clin Exp Pediatr. 2022;65(8):410-416. Published online December 8, 2021
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In children with primary dyslipidemia, functional myocardial abnormalities can occur at young age, including diastolic functional impairment of both ventricles and narrowing of the aortic valve and the sinus of Valsalva. Echocardiographic evaluations of high-risk children may be as important as biochemical evaluations.
- Editorial
- Neonatology (Perinatology)
- Factors to consider before implementing telemedicine protocols to manage neonatal jaundice (7 times)
- Heui Seung Jo
- Clin Exp Pediatr. 2022;65(8):403-404. Published online April 12, 2022
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In the rapidly changing environmental situation during the coronavirus disease 2019 outbreak, neonatal centers have developed telemedicine systems with extended coverage for neonatal monitoring and high-risk follow-up programs including neonatal hyperbilirubinemia. At this point, electronic health technology and noncontact medical system increase the effectiveness of rather than replacing the face-to-face visit and the opinions of experienced neonatologists.
- Other
- Three-dimensional printing technolgy in orthopedic oncology (7 times)
- Yongsung Kim
- Clin Exp Pediatr. 2022;65(10):496-497. Published online May 11, 2022
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Orthopedic oncology is one of the most active fields in applying 3-dimensional printing technology from preoperative planning to intraoperative procedures such as accurate resection of tumors and reconstruction of huge bone defects.
- Original Article
- Hematology
- Effect of cyclic pamidronate administration on osteoporosis in children with β-thalassemia major: a single-center study (7 times)
- Mahmoud A. El-Hawy, Nagwan Y. Saleh
- Clin Exp Pediatr. 2022;65(8):405-409. Published online June 7, 2022
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Question: What is the effect of cyclic pamidronate administration on osteoporosis in children with β-thalassemia major?
Finding: The dual-energy x-ray absorptiometry scan findings of children with β-thalassemia major and osteoporosis were improved after pamidronate administration.
Meaning: Cyclic pamidronate effectively treated osteoporosis in children with β-thalassemia major.
- Clinical Note
- Endocrinology
- Graves’ disease: an uncommon cause of late sequelae following DRESS (drug reaction with eosinophilia and systemic symptoms) (7 times)
- Therdpong Tempark, Amatanun Tangthanapalakul, Tawatchai Deekajorndech, Susheera Chatproedprai, Vichit Supornsilchai, Siriwan Wananukul
- Clin Exp Pediatr. 2022;65(12):602-604. Published online June 22, 2022
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- Review Article
- Infection
- Therapeutics for the treatment of coronavirus disease 2019 in children and adolescents (7 times)
- Soo-Han Choi, Jae Hong Choi, Ki Wook Yun
- Clin Exp Pediatr. 2022;65(8):377-386. Published online June 27, 2022
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· Children and adolescents with high risks for severe coronavirus disease 2019 (COVID-19) should be identified and proper treatment should be provided promptly according to the patient’s condition.
· Remdesivir can be considered for pediatric patients of all ages with COVID-19 who have an emergent or increase in supplemental oxygen.
· The use of corticosteroids is not recommended for patients with nonsevere COVID-19. Corticosteroids are recommended in children and adolescents with severe and critical COVID-19.
- Editorial
- Pulmonology
- Now lung ultrasound has been established as a fundamental examination in pediatric respiratory diseases (7 times)
- Kyunghoon Kim
- Clin Exp Pediatr. 2022;65(8):401-402. Published online July 13, 2022
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· Several studies demonstrated the usefulness of lung ultrasound in pediatric respiratory diseases including coronavirus disease 2019.
· Knowledge of lung ultrasound is increasing, and lung ultrasound has been established as a fundamental diagnostic examination for pediatric respiratory diseases.
- Original Article
- Neurobehavior
- Association between previous abortion history and risk of autism spectrum disorders among offspring: a meta-analysis (7 times)
- Ensiyeh Jenabi, Erfan Ayubi, Saeid Bashirian, Mahdieh Seyedi, Mohammad Rezaei
- Clin Exp Pediatr. 2023;66(2):70-75. Published online August 17, 2022
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Question: This study aimed to determine whether there is an association between previous abortion history and the risk of autism spectrum disorders (ASDs) among children.
Finding: We found that the risk of ASD associated with previous abortion history had an odds ratio of 1.64 (95% confidence interval, 1.28–2.0; I2=61.7%).
Meaning: These findings suggest a positive and significant association between history of previous abortion and risk of ASD in children.
- Clinical Note
- Other
- Novel PTRH2 gene variant causing IMNEPD (infantile-onset multisystem neurologic, endocrine, and pancreatic disease) in 2 Saudi siblings (7 times)
- Dalal K. Bubshait
- Clin Exp Pediatr. 2023;66(5):223-225. Published online March 23, 2023
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- Editorial
- Infection
- COVID-19 infection and vaccination among children (7 times)
- Amnuay Kleebayoon, Viroj Wiwanitkit
- Clin Exp Pediatr. 2023;66(12):531-532. Published online August 30, 2023
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· Coronavirus disease 2019 (OVID-19) infection and immunization have been linked with kidney problems; however, causality has not been proven.
· Concern about confounders is usually needed.
· Correspondence about a published article on the COVID-19 vaccine
- Correspondence
- General Pediatrics
- Letter to the editor: Age-, sex-, and height-based blood pressure reference charts, Yazd children 6-18 years, Iran (6 times)
- Amar Taksande
- Clin Exp Pediatr. 2023;66(9):412-413. Published online October 27, 2021
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- Original Article
- Developmental and Behavioral Medicine
- Effectiveness of obesity interventions among South Korean children and adolescents and importance of the type of intervention component: a meta-analysis (6 times)
- Siyoung Choe, Jaesin Sa, Jean-Philippe Chaput, Deokjin Kim
- Clin Exp Pediatr. 2022;65(2):98-107. Published online November 23, 2021
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Question: What is the overall effect of obesity interventions among Korean children and what affects their effectiveness?
Finding: Interventions were strongly favored over controls. Interventions including at least one physical activity component were significantly better than those that did not. Sex, age, baseline weight category, intervention duration, and the number of intervention components were not significant.
Meaning: Future obesity interventions for Korean children must seek to include physical activity components.
- Editorial
- Infection
- Importance of maintaining a high childhood vaccination rate and surveillance program against Japanese encephalitis in Korea (6 times)
- Su Eun Park
- Clin Exp Pediatr. 2022;65(3):127-128. Published online February 16, 2022
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∙ Recent epidemiologic changes of Japanese encephalitis (JE) in Korea are area (rural to urban or suburban) and age shift (children to adult).
∙ Although the main factors contributing to recent epidemiologic changes of JE are not well identified, maintaining high vaccination rates of JE appear to be important in preventing of JE in all age groups.
∙ Continuous surveillance for epidemiology and seroprevalence should be carried out.
- Correspondence and Reply
- Neurobehavior
- Association between polycystic ovary syndrome and risk of attention-deficit/hyperactivity disorder in offspring: a meta-analysis (6 times)
- Ensiyeh Jenabi
- Clin Exp Pediatr. 2022;65(3):152-152. Published online February 17, 2022
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- Editorial
- Nutrition
- Human milk oligosaccharides as immunonutrition key in early life (6 times)
- Jung Ok Shim
- Clin Exp Pediatr. 2022;65(7):344-345. Published online May 3, 2022
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· Human milk is a major source of immunonutrients for neonates and infants. Human milk oligosaccharides (HMOs) act as prebiotics and promote the growth of commensal bacteria.
· HMOs inhibit microorganism adhesion to the gut mucosa through interactions with the commensal microbiome and improve gut barrier function by increasing short-chain fatty acid mediated by bifidobacteria and immunomodulation.
· Several randomized controlled trials recently reported on HMOs.
- Review Article
- Neurobehavior
- Jeopardized mental health of children and adolescents in coronavirus disease 2019 pandemic (6 times)
- Bohyun Jin, Sohee Lee, Un Sun Chung
- Clin Exp Pediatr. 2022;65(7):322-329. Published online June 3, 2022
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∙ The coronavirus disease 2019 (COVID-19) pandemic has required preventive measures like self-quarantine, school closures, and lockdown, which ultimately make youth directly and indirectly vulnerable to depression, anxiety, posttraumatic stress disorder, and somatization.
∙ Child abuse is more common in the COVID-19 era than previously.
∙ Pediatricians should carefully examine parental and child mental health to directly and indirectly aid their physical and mental health.
- Editorial
- Nephrology (Genitourinary)
- Hypertension in adulthood is programmed during the perinatal period (6 times)
- Min Hyun Cho
- Clin Exp Pediatr. 2022;65(10):494-495. Published online August 12, 2022
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∙ Intrauterine growth restriction (IUGR) and preterm birth can be significant risk factors for the development of adult hypertension.
∙ Several perinatal factors of hypertension are related to IUGR, including renal, vascular, and rapid catch-up growth.
- Gastroenterology
- Is there a link between social media usage and functional gastrointestinal disorders in children? (6 times)
- Hae Jeong Lee
- Clin Exp Pediatr. 2023;66(4):169-170. Published online March 23, 2023
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Social media use has potential benefits and risks, including links to adverse health problems in children such as functional gastrointestinal disorders (FGIDs). Screen time control, emotional support, and parental guidance can help children navigate social media safely and reduce the risk of developing FGIDs.
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Impact Factor3.2
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8.02023CiteScore94nd percentilePowered by
